List of works - BethAnn McLaughlin

Alteration of isocitrate dehydrogenase following acute ischemic injury as a means to improve cellular energetic status in neuroadaptation

scientific article published on September 2013

Alterations in the E3 ligases Parkin and CHIP result in unique metabolic signaling defects and mitochondrial quality control issues

scientific article published on 26 August 2017

Analysis of Protein Targets by Oxidative Stress Using the OxyBlot and Biotin–Avidin-Capture Methodology

Analysis of a Nitroreductase-Based Hypoxia Sensor in Primary Neuronal Cultures

scientific article (publication date: 21 September 2016)

Assembly Dynamics and Stoichiometry of the Apoptosis Signal-regulating Kinase (ASK) Signalosome in Response to Electrophile Stress

scientific article

Assessing neuronal bioenergetic status

scientific article published on January 2011

C-terminus of heat shock cognate 70 interacting protein increases following stroke and impairs survival against acute oxidative stress

scientific article

CHIP Is an Essential Determinant of Neuronal Mitochondrial Stress Signaling

scientific article published on 20 January 2015

Caspase 3 activation is essential for neuroprotection in preconditioning

scholarly article

Correction: Electrophilic cyclopentenone neuroprostanes are anti-inflammatory mediators formed from the peroxidation of the ω -3 polyunsaturated fatty acid docosahexaenoic acid

scientific article published in 2019

Cyclopentenone eicosanoids as mediators of neurodegeneration: a pathogenic mechanism of oxidative stress-mediated and cyclooxygenase-mediated neurotoxicity

scientific article

Cyclopentenone isoprostanes are novel bioactive products of lipid oxidation which enhance neurodegeneration

scientific article

Defending harassers harms victims

scientific article published on 01 January 2019

Dopamine Neurotoxicity and Neurodegeneration

scholarly article

Dynamic Phosphorylation of Apoptosis Signal Regulating Kinase 1 (ASK1) in Response to Oxidative and Electrophilic Stress

scientific article

Electrophilic cyclopentenone isoprostanes in neurodegeneration

scientific article published on September 2007

Electrophilic cyclopentenone neuroprostanes are anti-inflammatory mediators formed from the peroxidation of the omega-3 polyunsaturated fatty acid docosahexaenoic acid

scientific article

Enrichment of elevated plasma F2t-isoprostane levels in individuals with autism who are stratified by presence of gastrointestinal dysfunction

scientific article published on 03 July 2013

Essential role of the redox-sensitive kinase p66shc in determining energetic and oxidative status and cell fate in neuronal preconditioning

scientific journal article

Genetic Models of Parkinson’s Disease

scholarly article published 2015

Guidelines for the use and interpretation of assays for monitoring autophagy

scientific article

Guidelines on experimental methods to assess mitochondrial dysfunction in cellular models of neurodegenerative diseases.

scientific article

Haploinsufficiency of the E3 ubiquitin ligase C-terminus of heat shock cognate 70 interacting protein (CHIP) produces specific behavioral impairments

scientific article

In vitro neurotoxicity of methylisothiazolinone, a commonly used industrial and household biocide, proceeds via a zinc and extracellular signal-regulated kinase mitogen-activated protein kinase-dependent pathway.

scientific article published in September 2002

Increasing gender diversity in the STEM research workforce

scientific article published on 01 November 2019

Induction of Neuronal Apoptosis by Thiol Oxidation

scientific article published on 01 November 2000

Intraarterial administration of norcantharidin attenuates ischemic stroke damage in rodents when given at the time of reperfusion: novel uses of endovascular capabilities

scientific article

Killer proteases and little strokes--how the things that do not kill you make you stronger

scientific article

Manganese exposure is cytotoxic and alters dopaminergic and GABAergic neurons within the basal ganglia

scientific article published on 5 May 2009

Metabolic multianalyte microphysiometry reveals extracellular acidosis is an essential mediator of neuronal preconditioning

scientific article published on 22 April 2012

Methylmalonate toxicity in primary neuronal cultures ⬇️

scientific article published on September 1, 1998

Neuron specific metabolic adaptations following multi-day exposures to oxygen glucose deprivation

scientific article published on 23 July 2010

Neuronal Preconditioning Requires the Mitophagic Activity of C-terminus of HSC70-Interacting Protein

Neurotoxic lipid peroxidation species formed by ischemic stroke increase injury

scientific article published on 19 August 2009

Neurovascular unit on a chip: implications for translational applications.

scientific article

Perioperative plasma F(2)-Isoprostane levels correlate with markers of impaired ventilation in infants with single-ventricle physiology undergoing stage 2 surgical palliation on the cardiopulmonary bypass

scientific article published on 12 February 2012

Poised for success: implementation of sound conditioning strategies to promote endogenous protective responses to stroke in patients

scientific article

Redox modification of proteins as essential mediators of CNS autophagy and mitophagy.

scientific article

Selective inhibitors of apoptotic caspases: implications for novel therapeutic strategies

scientific article published on 01 January 2001

Selective vulnerability of dopaminergic systems to Manganese: Relevance to occupational exposure

scholarly article by Jeannette Stankowski et al published May 2008 in Neurotoxicology and Teratology

Silent Cerebral Small Vessel Disease in Restless Legs Syndrome

scientific article published on 12 April 2016

Slit modulates cerebrovascular inflammation and mediates neuroprotection against global cerebral ischemia

scientific article published on 26 July 2007

The fatty acid oxidation product 15-A3t-isoprostane is a potent inhibitor of NFκB transcription and macrophage transformation

scientific article published on 23 September 2011

The kinder side of killer proteases: caspase activation contributes to neuroprotection and CNS remodeling

scientific article published on March 2004

The role of central nervous system development in late-onset neurodegenerative disorders

scientific article published on 08 May 2012

The selective p38 inhibitor SB-239063 protects primary neurons from mild to moderate excitotoxic injury

scientific article published in June 2002

The ubiquitin-proteasome system as a drug target in cerebrovascular disease: therapeutic potential of proteasome inhibitors

scientific article

p66(shc)'s role as an essential mitophagic molecule in controlling neuronal redox and energetic tone

scientific article published on 14 October 2010

List of works by BethAnn McLaughlin

Alteration of isocitrate dehydrogenase following acute ischemic injury as a means to improve cellular energetic status in neuroadaptation

Alterations in the E3 ligases Parkin and CHIP result in unique metabolic signaling defects and mitochondrial quality control issues

Analysis of Protein Targets by Oxidative Stress Using the OxyBlot and Biotin–Avidin-Capture Methodology

Analysis of a Nitroreductase-Based Hypoxia Sensor in Primary Neuronal Cultures

Assembly Dynamics and Stoichiometry of the Apoptosis Signal-regulating Kinase (ASK) Signalosome in Response to Electrophile Stress

Assessing neuronal bioenergetic status

C-terminus of heat shock cognate 70 interacting protein increases following stroke and impairs survival against acute oxidative stress

CHIP Is an Essential Determinant of Neuronal Mitochondrial Stress Signaling

Caspase 3 activation is essential for neuroprotection in preconditioning

Correction: Electrophilic cyclopentenone neuroprostanes are anti-inflammatory mediators formed from the peroxidation of the ω -3 polyunsaturated fatty acid docosahexaenoic acid

Cyclopentenone eicosanoids as mediators of neurodegeneration: a pathogenic mechanism of oxidative stress-mediated and cyclooxygenase-mediated neurotoxicity

Cyclopentenone isoprostanes are novel bioactive products of lipid oxidation which enhance neurodegeneration

Defending harassers harms victims

Dopamine Neurotoxicity and Neurodegeneration

Dynamic Phosphorylation of Apoptosis Signal Regulating Kinase 1 (ASK1) in Response to Oxidative and Electrophilic Stress

Electrophilic cyclopentenone isoprostanes in neurodegeneration

Electrophilic cyclopentenone neuroprostanes are anti-inflammatory mediators formed from the peroxidation of the omega-3 polyunsaturated fatty acid docosahexaenoic acid

Enrichment of elevated plasma F2t-isoprostane levels in individuals with autism who are stratified by presence of gastrointestinal dysfunction

Essential role of the redox-sensitive kinase p66shc in determining energetic and oxidative status and cell fate in neuronal preconditioning

Genetic Models of Parkinson’s Disease

Guidelines for the use and interpretation of assays for monitoring autophagy

Guidelines on experimental methods to assess mitochondrial dysfunction in cellular models of neurodegenerative diseases.

Haploinsufficiency of the E3 ubiquitin ligase C-terminus of heat shock cognate 70 interacting protein (CHIP) produces specific behavioral impairments

In vitro neurotoxicity of methylisothiazolinone, a commonly used industrial and household biocide, proceeds via a zinc and extracellular signal-regulated kinase mitogen-activated protein kinase-dependent pathway.

Increasing gender diversity in the STEM research workforce

Induction of Neuronal Apoptosis by Thiol Oxidation

Intraarterial administration of norcantharidin attenuates ischemic stroke damage in rodents when given at the time of reperfusion: novel uses of endovascular capabilities

Killer proteases and little strokes--how the things that do not kill you make you stronger

Manganese exposure is cytotoxic and alters dopaminergic and GABAergic neurons within the basal ganglia

Metabolic multianalyte microphysiometry reveals extracellular acidosis is an essential mediator of neuronal preconditioning

Methylmalonate toxicity in primary neuronal cultures ⬇️

Neuron specific metabolic adaptations following multi-day exposures to oxygen glucose deprivation

Neuronal Preconditioning Requires the Mitophagic Activity of C-terminus of HSC70-Interacting Protein

Neurotoxic lipid peroxidation species formed by ischemic stroke increase injury

Neurovascular unit on a chip: implications for translational applications.

Perioperative plasma F(2)-Isoprostane levels correlate with markers of impaired ventilation in infants with single-ventricle physiology undergoing stage 2 surgical palliation on the cardiopulmonary bypass

Poised for success: implementation of sound conditioning strategies to promote endogenous protective responses to stroke in patients

Redox modification of proteins as essential mediators of CNS autophagy and mitophagy.

Selective inhibitors of apoptotic caspases: implications for novel therapeutic strategies

Selective vulnerability of dopaminergic systems to Manganese: Relevance to occupational exposure

Silent Cerebral Small Vessel Disease in Restless Legs Syndrome

Slit modulates cerebrovascular inflammation and mediates neuroprotection against global cerebral ischemia

The fatty acid oxidation product 15-A3t-isoprostane is a potent inhibitor of NFκB transcription and macrophage transformation

The kinder side of killer proteases: caspase activation contributes to neuroprotection and CNS remodeling

The role of central nervous system development in late-onset neurodegenerative disorders

The selective p38 inhibitor SB-239063 protects primary neurons from mild to moderate excitotoxic injury

The ubiquitin-proteasome system as a drug target in cerebrovascular disease: therapeutic potential of proteasome inhibitors

p66(shc)'s role as an essential mitophagic molecule in controlling neuronal redox and energetic tone