List of works - Matthew C Canver

An erythroid enhancer of BCL11A subject to genetic variation determines fetal hemoglobin level.

scientific article published on October 2013

Analyzing CRISPR genome-editing experiments with CRISPResso

scientific article published on July 2016

Angiopoietin-like proteins stimulate HSPC development through interaction with notch receptor signaling

scientific journal article

BCL11A enhancer dissection by Cas9-mediated in situ saturating mutagenesis

scientific article

Characterization of genomic deletion efficiency mediated by clustered regularly interspaced palindromic repeats (CRISPR)/Cas9 nuclease system in mammalian cells.

scientific article

Customizing the genome as therapy for the β-hemoglobinopathies

scientific article

EHMT1 and EHMT2 inhibition induces fetal hemoglobin expression.

scientific article

Embryonic stem cells as sources of donor-independent platelets

scientific article published on 11 May 2015

Functional interrogation of non-coding DNA through CRISPR genome editing

scientific article published on 10 March 2017

Generation of genomic deletions in mammalian cell lines via CRISPR/Cas9

scientific article published on 3 January 2014

Genome-wide CRISPR-Cas9 Screen Identifies Leukemia-Specific Dependence on a Pre-mRNA Metabolic Pathway Regulated by DCPS.

scientific article published on 8 February 2018

High-Throughput Approaches to Pinpoint Function within the Noncoding Genome

scientific article

Human genetic variation alters CRISPR-Cas9 on- and off-targeting specificity at therapeutically implicated loci

scientific article published on 11 December 2017

Integrated design, execution, and analysis of arrayed and pooled CRISPR genome-editing experiments.

scientific article published on 12 April 2018

Interferon-α signaling promotes embryonic HSC maturation

scientific article published on 19 April 2016

Transcription factors LRF and BCL11A independently repress expression of fetal hemoglobin

scientific article

Variant-aware saturating mutagenesis using multiple Cas9 nucleases identifies regulatory elements at trait-associated loci.

scientific article

Visual evidence of a hemolytic transfusion reaction identified by blood bank testing after emergency blood transfusion

scientific article published on 01 October 2019

miRNA-embedded shRNAs for Lineage-specific BCL11A Knockdown and Hemoglobin F Induction

scientific article published on 17 June 2015

List of works by Matthew C Canver

An erythroid enhancer of BCL11A subject to genetic variation determines fetal hemoglobin level.

Analyzing CRISPR genome-editing experiments with CRISPResso

Angiopoietin-like proteins stimulate HSPC development through interaction with notch receptor signaling

BCL11A enhancer dissection by Cas9-mediated in situ saturating mutagenesis

Characterization of genomic deletion efficiency mediated by clustered regularly interspaced palindromic repeats (CRISPR)/Cas9 nuclease system in mammalian cells.

Customizing the genome as therapy for the β-hemoglobinopathies

EHMT1 and EHMT2 inhibition induces fetal hemoglobin expression.

Embryonic stem cells as sources of donor-independent platelets

Functional interrogation of non-coding DNA through CRISPR genome editing

Generation of genomic deletions in mammalian cell lines via CRISPR/Cas9

Genome-wide CRISPR-Cas9 Screen Identifies Leukemia-Specific Dependence on a Pre-mRNA Metabolic Pathway Regulated by DCPS.

High-Throughput Approaches to Pinpoint Function within the Noncoding Genome

Human genetic variation alters CRISPR-Cas9 on- and off-targeting specificity at therapeutically implicated loci

Integrated design, execution, and analysis of arrayed and pooled CRISPR genome-editing experiments.

Interferon-α signaling promotes embryonic HSC maturation

Transcription factors LRF and BCL11A independently repress expression of fetal hemoglobin

Variant-aware saturating mutagenesis using multiple Cas9 nucleases identifies regulatory elements at trait-associated loci.

Visual evidence of a hemolytic transfusion reaction identified by blood bank testing after emergency blood transfusion

miRNA-embedded shRNAs for Lineage-specific BCL11A Knockdown and Hemoglobin F Induction