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List of works by Matthew D Dun

Activation of protein phosphatase 2A in FLT3+ acute myeloid leukemia cells enhances the cytotoxicity of FLT3 tyrosine kinase inhibitors.

scientific article published on 18 June 2016

Activity-associated miRNA are packaged in Map1b-enriched exosomes released from depolarized neurons.

scientific article

Analysis of Epididymal Protein Synthesis and Secretion

scientific article published on 25 August 2018

Analysis of the small non-protein-coding RNA profile of mouse spermatozoa reveals specific enrichment of piRNAs within mature spermatozoa.

scientific article

Can Hemp Help? Low-THC Cannabis and Non-THC Cannabinoids for the Treatment of Cancer

scientific article published on 23 April 2020

Cell-Free DNA Blood Collection Tubes Are Appropriate for Clinical Proteomics: A Demonstration in Colorectal Cancer.

scientific article published on 24 February 2018

Cell-Free DNA as a Diagnostic Blood-Based Biomarker for Colorectal Cancer: A Systematic Review

scientific article published on 21 December 2018

Characteristics of the Epididymal Luminal Environment Responsible for Sperm Maturation and Storage.

scientific article published on 28 February 2018

Characterization of the early molecular changes in the glomeruli of Cd151 -/- mice highlights induction of mindin and MMP-10.

scientific article published on 22 November 2017

Cold Shock Domain Containing E1 (CSDE1) Protein is Overexpressed and can be Targeted to Inhibit Invasiveness in Pancreatic Cancer Cells

scientific article published on 13 March 2020

Correction: Mutant JAK3 phosphoproteomic profiling predicts synergism between JAK3 inhibitors and MEK/BCL2 inhibitors for the treatment of T-cell acute lymphoblastic leukemia

scientific article published on 01 December 2018

Development of novel PP2A activators for use in the treatment of acute myeloid leukaemia

scientific article published on 01 May 2016

Extracellular vesicles with altered tetraspanin CD9 and CD151 levels confer increased prostate cell motility and invasion.

scientific article published on 11 June 2018

Functional importance of PP2A regulatory subunit loss in breast cancer

scientific article

Furin processing dictates ectodomain shedding of human FAT1 cadherin

scientific article published on 18 February 2014

Harnessing the power of proteomics for identification of oncogenic, druggable signalling pathways in cancer

scientific article published on 13 March 2017

Inhibition of arachidonate 15-lipoxygenase prevents 4-hydroxynonenal-induced protein damage in male germ cells.

scientific article

Investigation of the expression and functional significance of the novel mouse sperm protein, a disintegrin and metalloprotease with thrombospondin type 1 motifs number 10 (ADAMTS10).

scientific article published on 28 March 2012

Involvement of multimeric protein complexes in mediating the capacitation-dependent binding of human spermatozoa to homologous zonae pellucidae

scientific article published on 13 June 2011

Modification of Crocodile Spermatozoa Refutes the Tenet That Post-testicular Sperm Maturation Is Restricted To Mammals

scientific article published on 02 August 2018

Mouse quiescin sulfhydryl oxidases exhibit distinct epididymal luminal distribution with segment-specific sperm surface associations

scientific article published on 01 November 2018

Mutant JAK3 phosphoproteomic profiling predicts synergism between JAK3 inhibitors and MEK/BCL2 inhibitors for the treatment of T-cell acute lymphoblastic leukemia.

scientific article published on 30 August 2017

Neuroproteins in Cancer: Assumed Bystanders Become Culprits

scientific article published on 05 June 2018

Next Generation Sequencing Analysis Reveals Segmental Patterns of microRNA Expression in Mouse Epididymal Epithelial Cells.

scientific article published on 13 August 2015

Peripheral Lipopolysaccharide Challenge Induces Long-Term Changes in Tyrosine Hydroxylase Regulation in the Adrenal Medulla.

scientific article

Pharmacological inhibition of arachidonate 15-lipoxygenase (ALOX15) protects human spermatozoa against oxidative stress.

scientific article published on 13 March 2018

Protein interaction screening identifies SH3RF1 as a new regulator of FAT1 protein levels

scientific article published on 27 January 2017

Proteogenomics: emergence and promise.

scientific article

Proteomic profiling of human uterine fibroids reveals upregulation of the extracellular matrix protein periostin.

scientific article

Proteomic profiling of mouse epididymosomes reveals their contributions to post-testicular sperm maturation

scientific article published on 13 September 2018

Proteotranscriptomic Profiling of 231-BR Breast Cancer Cells: Identification of Potential Biomarkers and Therapeutic Targets for Brain Metastasis

scientific article

Quantitative phosphoproteomics uncovers synergy between DNA-PK and FLT3 inhibitors in acute myeloid leukaemia

scientific article published on 16 October 2020

Salmeterol attenuates chemotactic responses in rhinovirus-induced exacerbation of allergic airways disease by modulating protein phosphatase 2A.

scientific article

Shwachman-Bodian-Diamond syndrome (SBDS) protein is a direct inhibitor of protein phosphatase 2A (PP2A) activity and overexpressed in acute myeloid leukaemia

scientific article published on 08 April 2020

Signal Transduction in Diffuse Intrinsic Pontine Glioma

scientific article published on 14 August 2019

Sperm-zona pellucida interaction: molecular mechanisms and the potential for contraceptive intervention.

scientific article published on January 2010

Targeting Oncogenic Signaling in Mutant FLT3 Acute Myeloid Leukemia: The Path to Least Resistance

scientific article published on 16 October 2018

The chaperonin containing TCP1 complex (CCT/TRiC) is involved in mediating sperm-oocyte interaction

scientific journal article

The effect of a patient-oriented treatment decision aid for risk factor management in patients with diabetes (PORTDA-diab): study protocol for a randomised controlled trial.

scientific article published on 21 November 2012

The presence of a truncated base excision repair pathway in human spermatozoa that is mediated by OGG1.

scientific article published in February 2013

The role of the molecular chaperone heat shock protein A2 (HSPA2) in regulating human sperm-egg recognition

scientific article