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List of works by Ruy Pérez-Montfort

1,2,4-thiadiazol-5(4H)-ones: a new class of selective inhibitors of Trypanosoma cruzi triosephosphate isomerase. Study of the mechanism of inhibition.

scientific article

3-H-[1,2]Dithiole as a New Anti-Trypanosoma cruzi Chemotype: Biological and Mechanism of Action Studies.

scientific article published on 12 August 2015

A guide to the effects of a large portion of the residues of triosephosphate isomerase on catalysis, stability, druggability, and human disease.

scientific article

A mechanism of acquired resistance to complement-mediated lysis by Entamoeba histolytica

scientific article published on 01 April 1997

A monoclonal antibody that inhibits Trypanosoma cruzi growth in vitro and its reaction with intracellular triosephosphate isomerase

scientific article published on 29 November 2007

A previously unrecognized subunit of the receptor for immunoglobulin E

scientific article published on 01 December 1983

A ribosomal misincorporation of Lys for Arg in human triosephosphate isomerase expressed in Escherichia coli gives rise to two protein populations

scientific article

A strategy based on thermal flexibility to design triosephosphate isomerase proteins with increased or decreased kinetic stability

scientific article published on 22 August 2018

Altered coupling states between calcium transport and (Ca2+, Mg2+)-ATPase in the AS-30D ascites hepatocarcinoma plasma membrane

scientific article published on 01 January 1991

An unusual triosephosphate isomerase from the early divergent eukaryote Giardia lamblia.

scientific article

Analysis of the structure and function of the receptor for immunoglobulin E

scientific article published on 01 December 1984

Catalysis and stability of triosephosphate isomerase from Trypanosoma brucei with different residues at position 14 of the dimer interface. Characterization of a catalytically competent monomeric enzyme.

scientific article published in April 2002

Catalytic classes of proteinases of Entamoeba histolytica

scientific article published on 01 November 1987

Causes of the decrease in fluorescence due to proteolysis of alpha-casein.

scientific article published on November 1990

Changes in the receptor for immunoglobulin E coincident with receptor-mediated stimulation of basophilic leukemia cells

scientific article published on 01 December 1983

Cloning, expression, purification and characterization of triosephosphate isomerase from Trypanosoma cruzi.

scientific article published in March 1997

Conserved cysteine 126 in triosephosphate isomerase is required not for enzymatic activity but for proper folding and stability.

scientific article published in March 2004

Control of the reactivation kinetics of homodimeric triosephosphate isomerase from unfolded monomers.

scientific article published in March 2003

Covalent cross-linking of subunits of the receptor for immunoglobulin E induced by immunoprecipitation

scientific article published on 01 December 1983

Crosstalk between the subunits of the homodimeric enzyme triosephosphate isomerase

scientific article published on 01 April 2007

Derivatization of the Interface Cysteine of Triosephosphate Isomerase fromTrypanosoma bruceiandTrypanosoma cruzias Probe of the Interrelationship between the Catalytic Sites and the Dimer Interface†

scientific article published on 01 March 1999

Development of bis-thiazoles as inhibitors of triosephosphate isomerase from Trypanosoma cruzi. Identification of new non-mutagenic agents that are active in vivo

scientific article

Differences in the intersubunit contacts in triosephosphate isomerase from two closely related pathogenic trypanosomes

scientific article

Different contribution of conserved amino acids to the global properties of triosephosphate isomerases

scientific article

Differential effects on enzyme stability and kinetic parameters of mutants related to human triosephosphate isomerase deficiency

scientific article published on 20 March 2018

Differential inactivation of rabbit and yeast triosephosphate isomerase: effect of oxidations produced by chloramine-T

scientific article published on 01 September 1994

Early expression of the receptor for advanced glycation end products in a toxic model produced by 6-hydroxydopamine in the rat striatum.

scientific article published on 18 February 2016

Enhancement of Antibody Production by a Learning Paradigm ⬇️

scientific article published on September 1, 1995

Entamoeba histolytica: role of amebic proteinases and polymorphonuclear leukocytes in acute experimental amebiasis in the rat

scientific article published on 01 December 1988

Expression and characterization of recombinant pyruvate phosphate dikinase from Entamoeba histolytica

scientific article published on 01 January 1998

Factors that control the reactivity of the interface cysteine of triosephosphate isomerase from Trypanosoma brucei and Trypanosoma cruzi.

scientific article published in March 2001

Highly specific inactivation of triosephosphate isomerase from Trypanosoma cruzi

scientific article

Identification of Amino Acids that Account for Long-Range Interactions in Two Triosephosphate Isomerases from Pathogenic Trypanosomes

scientific article

Identification of the critical residues responsible for differential reactivation of the triosephosphate isomerases of two trypanosomes

scientific article (publication date: October 2016)

Inactivation of triosephosphate isomerase from Trypanosoma cruzi by an agent that perturbs its dimer interface

scientific article

Insular cortex lesions impair the acquisition of conditioned immunosuppression.

scientific article

Interplay between Protein Thermal Flexibility and Kinetic Stability

scientific article

Key residues of loop 3 in the interaction with the interface residue at position 14 in triosephosphate isomerase from Trypanosoma brucei.

scientific article

Leishmania mexicana mexicana: genetic heterogeneity of mexican isolates revealed by restriction length polymorphism analysis of kinetoplast DNA

scientific article published on 01 August 2000

Loosely packed papain prosegment displays inhibitory activity.

scientific article published on 29 December 2005

Massive screening yields novel and selective Trypanosoma cruzi triosephosphate isomerase dimer-interface-irreversible inhibitors with anti-trypanosomal activity.

scientific article

Measurement of casein digestion by a fluorometric method

scientific article published on 01 February 1989

Modeling the interaction between quinolinate and the receptor for advanced glycation end products (RAGE): relevance for early neuropathological processes

scientific article

Multi-Anti-Parasitic Activity of Arylidene Ketones and Thiazolidene Hydrazines against Trypanosoma cruzi and Leishmania spp.

scientific article published on 7 May 2017

New chemotypes as Trypanosoma cruzi triosephosphate isomerase inhibitors: a deeper insight into the mechanism of inhibition.

scientific article published on 13 February 2013

Noncovalently and covalently bound lipid on the receptor for immunoglobulin E

scientific article published on 01 December 1985

Novel and Selective Triosephosphate Isomerase Inhibitors with Acaricidal Activity

scientific article published on 23 August 2018

PCR for identification of species causing American cutaneous leishmaniasis

scientific article published on 12 November 2008

Pathogenesis of Acute Experimental Amebic Liver Abscess in Hamsters

scientific article published on December 1, 1991

Polymorphism analysis of the internal transcribed spacer and small subunit of ribosomal RNA genes of Leishmania mexicana.

scientific article published on 27 June 2002

Potent and Selective Inhibitors of Trypanosoma cruzi Triosephosphate Isomerase with Concomitant Inhibition of Cruzipain: Inhibition of Parasite Growth through Multitarget Activity.

scientific article

Proteinases of Entamoeba histolytica associated with different subcellular fractions

scientific article published on 01 January 1989

Proteolysis of soluble IgE-receptor complexes: localization of sites on IgE which interact with the Fc receptor

scientific article published on 01 September 1982

Proteolytic activity in extracts of invasive cervical carcinoma and precursor lesions

scientific article published on 01 January 1995

Purification and immunologic characterization of a 30-kDa cysteine proteinase of Entamoeba histolytica

scientific article published on 01 January 1994

Purification of alcohol dehydrogenase from Entamoeba histolytica and Saccharomyces cerevisiae using zinc-affinity chromatography

scientific article published on 01 August 1997

Pyruvate kinase revisited: the activating effect of K+.

scientific article

Reactivation of triosephosphate isomerase from three trypanosomatids and human: effect of Suramin ⬇️

scientific article published on May 15, 1998

Role of leukocytes and amebic proteinases in experimental rat testicular necrosis produced by Entamoeba histolytica

scientific article published on 01 January 1991

Structural and biochemical characterization of a recombinant triosephosphate isomerase from Rhipicephalus (Boophilus) microplus

scientific article

Structural basis of human triosephosphate isomerase deficiency: mutation E104D is related to alterations of a conserved water network at the dimer interface

scientific article

Susceptibility to proteolysis of triosephosphate isomerase from two pathogenic parasites: characterization of an enzyme with an intact and a nicked monomer

scientific article

The conserved salt bridge linking two C-terminal beta/alpha units in homodimeric triosephosphate isomerase determines the folding rate of the monomer

scientific article published on 01 August 2008

The effect of specific proline residues on the kinetic stability of the triosephosphate isomerases of two trypanosomes.

scientific article published on 21 December 2016

The efficacy of pentamidine combined with allopurinol and immunotherapy for the treatment of patients with diffuse cutaneous leishmaniasis

scientific article published on 01 March 1999

The importance of arginine codons AGA and AGG for the expression in E. coli of triosephosphate isomerase from seven different species.

scientific article

The interfaces of oligomeric proteins as targets for drug design against enzymes from parasites.

scientific article

The stability and formation of native proteins from unfolded monomers is increased through interactions with unrelated proteins

scientific article

Thermodynamic and kinetic destabilization of triosephosphate isomerase resulting from the mutation of conserved and non-conserved cysteines

scientific article published on 01 December 2011

Three unrelated and unexpected amino acids determine the susceptibility of the interface cysteine to a sulfhydryl reagent in the triosephosphate isomerases of two trypanosomes

scientific article published on 17 January 2018

Treatment of two patients with diffuse cutaneous leishmaniasis caused by Leishmania mexicana modifies the immunohistological profile but not the disease outcome

scientific article published on 01 December 1999

Urokinase-type plasminogen activator and plasminogen activator inhibitors (PAI-1 and PAI-2) in extracts of invasive cervical carcinoma and precursor lesions

scientific article published on 01 March 1998

Using evolutionary changes to achieve species-specific inhibition of enzyme action — studies with triosephosphate isomerase

scientific article published on 01 December 1995

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