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List of works by June Goto

A hypomorphic allele of Tsc2 highlights the role of TSC1/TSC2 in signaling to AKT and models mild human TSC2 alleles

scientific article published on 08 April 2009

A mutation in Ccdc39 causes neonatal hydrocephalus with abnormal motile cilia development in mice

scientific article published on 9 January 2018

Altered gene expression in the adult brain of fyn-deficient mice.

scientific article published in February 2004

Brain-expressed X-linked 2 Is Pivotal for Hyperactive Mechanistic Target of Rapamycin (mTOR)-mediated Tumorigenesis

scientific article

Correction: Stochastic Model of Tsc1 Lesions in Mouse Brain

scientific article published on 7 November 2013

Exome sequencing implicates genetic disruption of prenatal neuro-gliogenesis in sporadic congenital hydrocephalus

scientific article published on 19 October 2020

Impaired neural differentiation and glymphatic CSF flow in the Ccdc39 rat model of neonatal hydrocephalus: genetic interaction with L1cam

scientific article published on 21 November 2019

Loss of Fyn tyrosine kinase on the C57BL/6 genetic background causes hydrocephalus with defects in oligodendrocyte development.

scientific article published on 4 March 2008

Mammalian target of rapamycin up-regulation of pyruvate kinase isoenzyme type M2 is critical for aerobic glycolysis and tumor growth ⬇️

scientific article published on February 15, 2011

NR2B tyrosine phosphorylation modulates fear learning as well as amygdaloid synaptic plasticity

scientific article

Neuronal Tsc1/2 complex controls autophagy through AMPK-dependent regulation of ULK1

scientific journal article

Prenatal rapamycin results in early and late behavioral abnormalities in wildtype C57BL/6 mice

scientific article

Regulable neural progenitor-specific Tsc1 loss yields giant cells with organellar dysfunction in a model of tuberous sclerosis complex

scientific article published on 24 October 2011

Smooth muscle protein-22-mediated deletion of Tsc1 results in cardiac hypertrophy that is mTORC1-mediated and reversed by rapamycin ⬇️

scientific article published on January 6, 2011

Stochastic model of Tsc1 lesions in mouse brain

scientific article

Survival benefit and phenotypic improvement by hamartin gene therapy in a tuberous sclerosis mouse brain model.

scientific article published on 24 May 2015

TSC1 loss synergizes with KRAS activation in lung cancer development in the mouse and confers rapamycin sensitivity.

scientific article

Therapeutic value of prenatal rapamycin treatment in a mouse brain model of tuberous sclerosis complex.

scientific article published on September 2011

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