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List of works by András Málnási-Csizmadia

A highly soluble, non-phototoxic, non-fluorescent blebbistatin derivative.

scientific article

A novel actin binding site of myosin required for effective muscle contraction

scientific article published on 12 February 2012

Analysis of nucleotide binding to Dictyostelium myosin II motor domains containing a single tryptophan near the active site.

scientific article published on 23 April 2002

Azidoblebbistatin, a photoreactive myosin inhibitor.

scientific article

Breaking the hierarchy--a new cluster selection mechanism for hierarchical clustering methods.

scientific article published on 19 October 2009

Combining EPR with fluorescence spectroscopy to monitor conformational changes at the myosin nucleotide pocket.

scientific article published on 28 December 2009

Contribution of 2D and 3D structural features of drug molecules in the prediction of Drug Profile Matching.

scientific article

Differential actin binding along the PEVK domain of skeletal muscle titin.

scientific article published on 26 October 2004

Dimerization of the head-rod junction of scallop myosin

scientific article published on 01 November 1998

Emerging complex pathways of the actomyosin powerstroke.

scientific article

Engineering Dictyostelium discoideum myosin II for the introduction of site-specific fluorescence probes.

scientific article

Enzyme kinetics above denaturation temperature: a temperature-jump/stopped-flow apparatus.

scientific article published on 29 September 2006

Experimental confirmation of new drug-target interactions predicted by Drug Profile Matching.

scientific article published on 23 October 2013

High-Field High-Repetition-Rate Sources for the Coherent THz Control of Matter

scientific article

Identification of PPARγ ligands with One-dimensional Drug Profile Matching

scientific article published on 02 September 2013

Internal friction in enzyme reactions.

scientific article published on January 2013

Kinetic mechanism of human dUTPase, an essential nucleotide pyrophosphatase enzyme

scientific article

Localization and characterization of the inhibitory Ca2+-binding site of Physarum polycephalum myosin II.

scientific article published on 16 May 2003

Magnesium modulates actin binding and ADP release in myosin motors

scientific article

Modeling Polypharmacological Profiles by Affinity Fingerprinting

scientific article

Modulating Beta-Cardiac Myosin Function at the Molecular and Tissue Levels.

scientific article

Molecular tattoo: subcellular confinement of drug effects

scientific article

Myosin cleft movement and its coupling to actomyosin dissociation.

scientific article published on 21 September 2003

Myosin complexed with ADP and blebbistatin reversibly adopts a conformation resembling the start point of the working stroke.

scientific article

Nucleotide pocket thermodynamics measured by EPR reveal how energy partitioning relates myosin speed to efficiency

scientific article

Probing conformational plasticity of the activation domain of trypsin: the role of glycine hinges.

scientific article published on 15 January 2008

Relating the shape of protein binding sites to binding affinity profiles: is there an association?

scientific article

Reversible movement of switch 1 loop of myosin determines actin interaction

scientific article published on January 2007

Selective perturbation of the myosin recovery stroke by point mutations at the base of the lever arm affects ATP hydrolysis and phosphate release

scientific article published on 21 April 2007

Site directed mutagenesis at position 193 of human trypsin 4 alters the rate of conformational change during activation: role of local internal viscosity in protein dynamics.

scientific article published in June 2007

Switch movements and the myosin crossbridge stroke.

scientific article

Temperature dependence of internal friction in enzyme reactions

scientific article published on 09 May 2011

The dynamics of the relay loop tryptophan residue in the Dictyostelium myosin motor domain and the origin of spectroscopic signals.

scientific article

The effect of F-actin on the relay helix position of myosin II, as revealed by tryptophan fluorescence, and its implications for mechanochemical coupling.

scientific article published in December 2004

Virtual Affinity Fingerprints for Target Fishing: A New Application of Drug Profile Matching ⬇️

scientific article published on December 18, 2012

Viscosity dependence of passage through a fluctuating bottleneck.

scientific article published on December 2014

para-Nitroblebbistatin, the non-cytotoxic and photostable myosin II inhibitor

scientific article

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