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List of works by Sylvia C Hewitt

A distal super enhancer mediates estrogen-dependent mouse uterine–specific gene transcription of Insulin-like growth factor 1 (Igf1)

article

Activation of a Uterine Insulin-Like Growth Factor I Signaling Pathway by Clinical and Environmental Estrogens: Requirement of Estrogen Receptor-α

An estrogen receptor-alpha knock-in mutation provides evidence of ligand-independent signaling and allows modulation of ligand-induced pathways in vivo

scientific article published on 13 March 2008

Biological and biochemical consequences of global deletion of exon 3 from the ER alpha gene

scientific article

Cell biology. A hand to support the implantation window

scientific article published on February 2011

Cell-type specific analysis of physiological action of estrogen in mouse oviducts

scientific article published on 01 May 2021

DNA Sequence Constraints Define Functionally Active Steroid Nuclear Receptor Binding Sites in Chromatin

scientific article published in October 2017

Development of phenotypic and transcriptional biomarkers to evaluate relative activity of potentially estrogenic chemicals in ovariectomized mice

scientific article

Diarylheptanoid phytoestrogens isolated from the medicinal plant Curcuma comosa: biologic actions in vitro and in vivo indicate estrogen receptor-dependent mechanisms

scientific article published on 23 March 2009

Distinct functions and regulation of epithelial progesterone receptor in the mouse cervix, vagina, and uterus

scientific article published on 17 March 2016

Estradiol regulates the thioredoxin antioxidant system in the mouse uterus

scientific article published on 2 September 2004

Estren behaves as a weak estrogen rather than a nongenomic selective activator in the mouse uterus

scientific article published on 9 February 2006

Estrogen Hormone Biology.

scientific article

Estrogen Receptors: New Directions in the New Millennium

Estrogen down-regulation of the Scx gene is mediated by the opposing strand-overlapping gene Bop1.

scientific article

Estrogen receptor (ER)α-regulated lipocalin 2 expression in adipose tissue links obesity with breast cancer progression

scientific article

Estrogen receptor alpha protects pancreatic beta cells from apoptosis by preserving mitochondrial function and suppressing endoplasmic reticulum stress

scientific article

Estrogen receptor α (ERα)-binding super enhancers drive key mediators that control uterine estrogen responses in mice

scientific article published on 30 April 2020

Estrogen receptor α controls metabolism in white and brown adipocytes by regulating Polg1 and mitochondrial remodeling

scientific article published on 01 August 2020

Estrogen receptor-dependent genomic responses in the uterus mirror the biphasic physiological response to estrogen

scientific article published on 31 July 2003

Estrogen receptors: structure, mechanisms and function

scientific article

Estrogen-induced proliferation of uterine epithelial cells is independent of estrogen receptor alpha binding to classical estrogen response elements.

scientific article published on 17 July 2006

Estrogen-mediated regulation of Igf1 transcription and uterine growth involves direct binding of estrogen receptor alpha to estrogen-responsive elements

scientific article

Estrogenic activity of bisphenol A and 2,2-bis(p-hydroxyphenyl)-1,1,1-trichloroethane (HPTE) demonstrated in mouse uterine gene profiles

scientific article

Estrogens Promote Misfolded Proinsulin Degradation to Protect Insulin Production and Delay Diabetes

scientific article published on 01 July 2018

Ex3αERKO male infertility phenotype recapitulates the αERKO male phenotype

scientific article

Extranuclear estrogen receptor-alpha stimulates NeuroD1 binding to the insulin promoter and favors insulin synthesis

scientific article

FOXA1 is an essential determinant of ERalpha expression and mammary ductal morphogenesis

scientific article

Genetic control of ductal morphology, estrogen-induced ductal growth, and gene expression in female mouse mammary gland

scientific article

Genetic control of estrogen-regulated transcriptional and cellular responses in mouse uterus

scientific article published on 31 January 2013

Global uterine genomics in vivo: microarray evaluation of the estrogen receptor alpha-growth factor cross-talk mechanism

scientific article published on 4 November 2004

Hormone signaling and fatty liver in females: analysis of estrogen receptor α mutant mice

scientific article published on 21 February 2017

Induction of mammary gland development in estrogen receptor-alpha knockout mice

scientific journal article

Juxtacrine Activity of Estrogen Receptor α in Uterine Stromal Cells is Necessary for Estrogen-Induced Epithelial Cell Proliferation

scientific article published on 21 August 2017

Lessons in estrogen biology from knockout and transgenic animals

scientific article

Myeloid-specific estrogen receptor alpha deficiency impairs metabolic homeostasis and accelerates atherosclerotic lesion development

scientific article

Novel DNA motif binding activity observed in vivo with an estrogen receptor α mutant mouse

scientific article

Oestrogen receptor knockout mice: roles for oestrogen receptors alpha and beta in reproductive tissues

scientific article

Oviductal estrogen receptor α signaling prevents protease-mediated embryo death

scientific article

Postnatal sex reversal of the ovaries in mice lacking estrogen receptors alpha and beta.

scientific article

Profile of estrogen-responsive genes in an estrogen-specific mammary gland outgrowth model

scientific article published on August 2009

Progesterone action and responses in the alphaERKO mouse.

scientific article

Requirement of estrogen receptor-alpha in insulin-like growth factor-1 (IGF-1)-induced uterine responses and in vivo evidence for IGF-1/estrogen receptor cross-talk

scientific article published on 21 December 2001

Research resource: whole-genome estrogen receptor α binding in mouse uterine tissue revealed by ChIP-seq

scientific article

Role of ERα in Mediating Female Uterine Transcriptional Responses to IGF1.

scientific article published on 6 June 2017

Role of estrogen receptor signaling required for endometriosis-like lesion establishment in a mouse model

scientific article

SCA-1 Labels a Subset of Estrogen-Responsive Bipotential Repopulating Cells within the CD24+ CD49fhi Mammary Stem Cell-Enriched Compartment

scientific article published on 20 January 2017

Selective disruption of ER{alpha} DNA-binding activity alters uterine responsiveness to estradiol

scientific article published on 07 October 2009

Signal transduction. A new mediator for an old hormone?

scientific article

Skeletal muscle action of estrogen receptor α is critical for the maintenance of mitochondrial function and metabolic homeostasis in females

scientific article published on April 2016

The Five W’s of Progesterone Receptors A and B: Now We Know Where and When

scientific article published on 01 December 2006

The natural estrogenic compound diarylheptanoid (D3): in vitro mechanisms of action and in vivo uterine responses via estrogen receptor α

scientific article published on 18 January 2013

The role of genetics in estrogen responses: a critical piece of an intricate puzzle

scientific article

Update on animal models developed for analyses of estrogen receptor biological activity

scientific article published on September 2003

Upregulation of estrogen receptor expression in the uterus of ovariectomized B6C3F1 mice and Ishikawa cells treated with bromoethane

scientific article

Uterine epithelial cell estrogen receptor alpha-dependent and -independent genomic profiles that underlie estrogen responses in mice

scientific article published on 10 September 2014

Uterine epithelial estrogen receptor α is dispensable for proliferation but essential for complete biological and biochemical responses

scientific article

Uterine gland formation in mice is a continuous process, requiring the ovary after puberty, but not after parturition

scientific article

What's new in estrogen receptor action in the female reproductive tract

scientific article

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