List of works - Marta Fumagalli

A role for P2X7 in microglial proliferation

scientific article published on 6 July 2006

Abnormal Upregulation of GPR17 Receptor Contributes to Oligodendrocyte Dysfunction in SOD1 G93A Mice

scientific article published on 31 March 2020

Blockade of A2A adenosine receptors prevents basic fibroblast growth factor-induced reactive astrogliosis in rat striatal primary astrocytes

scientific journal article

CNS remyelination as a novel reparative approach to neurodegenerative diseases: The roles of purinergic signaling and the P2Y-like receptor GPR17

scientific article

Calcitonin Gene-Related Peptide-Mediated Enhancement of Purinergic Neuron/Glia Communication by the Algogenic Factor Bradykinin in Mouse Trigeminal Ganglia from Wild-Type and R192Q Cav2.1 Knock-In Mice: Implications for Basic Mechanisms of Migraine P

article

Cellular and molecular characterization of multipolar Map5-expressing cells: a subset of newly generated, stage-specific parenchymal cells in the mammalian central nervous system

scientific article

Changes of the GPR17 receptor, a new target for neurorepair, in neurons and glial cells in patients with traumatic brain injury

scientific article published on 26 June 2013

Cloning, pharmacological characterisation and distribution of the rat G-protein-coupled P2Y(13) receptor

scientific journal article

CysLT1 leukotriene receptor antagonists inhibit the effects of nucleotides acting at P2Y receptors

scientific article

Differential local tissue permissiveness influences the final fate of GPR17-expressing oligodendrocyte precursors in two distinct models of demyelination

scientific article published on 9 February 2018

Does GRK-β arrestin machinery work as a "switch on" for GPR17-mediated activation of intracellular signaling pathways?

scientific article published on 5 March 2014

Expression and contribution of satellite glial cells purinoceptors to pain transmission in sensory ganglia: an update

scientific article

Functional characterization of two isoforms of the P2Y-like receptor GPR17: [35S]GTPgammaS binding and electrophysiological studies in 1321N1 cells

scientific article

High Yield of Adult Oligodendrocyte Lineage Cells Obtained from Meningeal Biopsy

scientific article published on 12 October 2017

How to reprogram microglia toward beneficial functions

scientific article published on 08 September 2018

International Union of Pharmacology LVIII: update on the P2Y G protein-coupled nucleotide receptors: from molecular mechanisms and pathophysiology to therapy

scientific article

Intertwining extracellular nucleotides and their receptors with Ca2+ in determining adult neural stem cell survival, proliferation and final fate

scientific article

Microglia is a key player in the reduction of stroke damage promoted by the new antithrombotic agent ticagrelor

scientific article

Nucleotide-mediated calcium signaling in rat cortical astrocytes: Role of P2X and P2Y receptors

scientific article published in September 2003

Oligodendrocyte Dysfunction in Amyotrophic Lateral Sclerosis: Mechanisms and Therapeutic Perspectives

scientific article published in 2021

P2 receptors in human heart: upregulation of P2X6 in patients undergoing heart transplantation, interaction with TNFalpha and potential role in myocardial cell death

scientific article published on 19 October 2005

P2Y receptors in brain astroglial cells: Identification of a gliotic P2Y receptor coupled to activation of a calcium-independent ras/ERK1/2 pathway

article published in 2003

Pathophysiological Role of Purines and Pyrimidines in Neurodevelopment: Unveiling New Pharmacological Approaches to Congenital Brain Diseases

scientific article published on 19 December 2017

Pathophysiological roles of extracellular nucleotides in glial cells: differential expression of purinergic receptors in resting and activated microglia

Pharmacological Properties and Biological Functions of the GPR17 Receptor, a Potential Target for Neuro-Regenerative Medicine.

scientific article

Phenotypic changes, signaling pathway, and functional correlates of GPR17-expressing neural precursor cells during oligodendrocyte differentiation

scientific article

Purinergic control of T cell activation by ATP released through pannexin-1 hemichannels.

scientific article published on 30 September 2008

Purinergic trophic signalling in glial cells: functional effects and modulation of cell proliferation, differentiation, and death ⬇️

scientific article published on April 12, 2012

Purinoceptor-mediated calcium signaling in primary neuron-glia trigeminal cultures

article

Regulation and signaling of the GPR17 receptor in oligodendroglial cells

scientific article published on 22 February 2020

Role of purinergic signalling in neuro-immune cells and adult neural progenitors ⬇️

scientific article published on June 1, 2011

THE CONCISE GUIDE TO PHARMACOLOGY 2021/22: G protein‐coupled receptors ⬇️

journal article from 'British Journal of Pharmacology' published in 2021

TNF Production and Release from Microglia via Extracellular Vesicles: Impact on Brain Functions

scientific article published on 23 September 2020

The GPR17 receptor in NG2 expressing cells: focus on in vivo cell maturation and participation in acute trauma and chronic damage

scientific article

The orphan receptor GPR17 identified as a new dual uracil nucleotides/cysteinyl-leukotrienes receptor

scientific article

The recently identified P2Y-like receptor GPR17 is a sensor of brain damage and a new target for brain repair

scientific article

The regulated expression, intracellular trafficking, and membrane recycling of the P2Y-like receptor GPR17 in Oli-neu oligodendroglial cells

scientific article published on 3 January 2013

The role of oligodendrocyte precursor cells expressing the GPR17 receptor in brain remodeling after stroke

scientific article published on 8 June 2017

The ubiquitin ligase Mdm2 controls oligodendrocyte maturation by intertwining mTOR with G protein-coupled receptor kinase 2 in the regulation of GPR17 receptor desensitization

scientific article published on 31 July 2015

UDP-glucose enhances outward K(+) currents necessary for cell differentiation and stimulates cell migration by activating the GPR17 receptor in oligodendrocyte precursors

scientific article published on 2 May 2013

List of works by Marta Fumagalli

A role for P2X7 in microglial proliferation

Abnormal Upregulation of GPR17 Receptor Contributes to Oligodendrocyte Dysfunction in SOD1 G93A Mice

Blockade of A2A adenosine receptors prevents basic fibroblast growth factor-induced reactive astrogliosis in rat striatal primary astrocytes

CNS remyelination as a novel reparative approach to neurodegenerative diseases: The roles of purinergic signaling and the P2Y-like receptor GPR17

Calcitonin Gene-Related Peptide-Mediated Enhancement of Purinergic Neuron/Glia Communication by the Algogenic Factor Bradykinin in Mouse Trigeminal Ganglia from Wild-Type and R192Q Cav2.1 Knock-In Mice: Implications for Basic Mechanisms of Migraine P

Cellular and molecular characterization of multipolar Map5-expressing cells: a subset of newly generated, stage-specific parenchymal cells in the mammalian central nervous system

Changes of the GPR17 receptor, a new target for neurorepair, in neurons and glial cells in patients with traumatic brain injury

Cloning, pharmacological characterisation and distribution of the rat G-protein-coupled P2Y(13) receptor

CysLT1 leukotriene receptor antagonists inhibit the effects of nucleotides acting at P2Y receptors

Differential local tissue permissiveness influences the final fate of GPR17-expressing oligodendrocyte precursors in two distinct models of demyelination

Does GRK-β arrestin machinery work as a "switch on" for GPR17-mediated activation of intracellular signaling pathways?

Expression and contribution of satellite glial cells purinoceptors to pain transmission in sensory ganglia: an update

Functional characterization of two isoforms of the P2Y-like receptor GPR17: [35S]GTPgammaS binding and electrophysiological studies in 1321N1 cells

High Yield of Adult Oligodendrocyte Lineage Cells Obtained from Meningeal Biopsy

How to reprogram microglia toward beneficial functions

International Union of Pharmacology LVIII: update on the P2Y G protein-coupled nucleotide receptors: from molecular mechanisms and pathophysiology to therapy

Intertwining extracellular nucleotides and their receptors with Ca2+ in determining adult neural stem cell survival, proliferation and final fate

Microglia is a key player in the reduction of stroke damage promoted by the new antithrombotic agent ticagrelor

Nucleotide-mediated calcium signaling in rat cortical astrocytes: Role of P2X and P2Y receptors

Oligodendrocyte Dysfunction in Amyotrophic Lateral Sclerosis: Mechanisms and Therapeutic Perspectives

P2 receptors in human heart: upregulation of P2X6 in patients undergoing heart transplantation, interaction with TNFalpha and potential role in myocardial cell death

P2Y receptors in brain astroglial cells: Identification of a gliotic P2Y receptor coupled to activation of a calcium-independent ras/ERK1/2 pathway

Pathophysiological Role of Purines and Pyrimidines in Neurodevelopment: Unveiling New Pharmacological Approaches to Congenital Brain Diseases

Pathophysiological roles of extracellular nucleotides in glial cells: differential expression of purinergic receptors in resting and activated microglia

Pharmacological Properties and Biological Functions of the GPR17 Receptor, a Potential Target for Neuro-Regenerative Medicine.

Phenotypic changes, signaling pathway, and functional correlates of GPR17-expressing neural precursor cells during oligodendrocyte differentiation

Purinergic control of T cell activation by ATP released through pannexin-1 hemichannels.

Purinergic trophic signalling in glial cells: functional effects and modulation of cell proliferation, differentiation, and death ⬇️

Purinoceptor-mediated calcium signaling in primary neuron-glia trigeminal cultures

Regulation and signaling of the GPR17 receptor in oligodendroglial cells

Role of purinergic signalling in neuro-immune cells and adult neural progenitors ⬇️

THE CONCISE GUIDE TO PHARMACOLOGY 2021/22: G protein‐coupled receptors ⬇️

TNF Production and Release from Microglia via Extracellular Vesicles: Impact on Brain Functions

The GPR17 receptor in NG2 expressing cells: focus on in vivo cell maturation and participation in acute trauma and chronic damage

The orphan receptor GPR17 identified as a new dual uracil nucleotides/cysteinyl-leukotrienes receptor

The recently identified P2Y-like receptor GPR17 is a sensor of brain damage and a new target for brain repair

The regulated expression, intracellular trafficking, and membrane recycling of the P2Y-like receptor GPR17 in Oli-neu oligodendroglial cells

The role of oligodendrocyte precursor cells expressing the GPR17 receptor in brain remodeling after stroke

The ubiquitin ligase Mdm2 controls oligodendrocyte maturation by intertwining mTOR with G protein-coupled receptor kinase 2 in the regulation of GPR17 receptor desensitization

UDP-glucose enhances outward K(+) currents necessary for cell differentiation and stimulates cell migration by activating the GPR17 receptor in oligodendrocyte precursors