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List of works by Joseph Makhema

A Comparison of Hepatitis B Virus Infection in HIV-infected and HIV-uninfected Participants Enrolled in a Multi-National Clinical Trial: HPTN 052.

scientific article

A randomized trial of Mogen clamp versus Plastibell for neonatal male circumcision in Botswana

scientific article published on April 2013

A seronegative case of HIV-1 subtype C infection in Botswana

scientific article

A1 Pairwise diversity and tMRCA as potential markers of HIV infection recency.

scientific article published on 17 April 2018

Abacavir alters the transcription of inflammatory cytokines in virologically suppressed, HIV-infected women

scientific article

Acceptability of infant male circumcision as part of HIV prevention and male reproductive health efforts in Gaborone, Botswana, and surrounding areas

scientific article

Afri-Can Forum 2 : Johannesburg, South Africa. 16-18 February 2015

Analysis of genetic linkage of HIV from couples enrolled in the HIV Prevention Trials Network 052 trial

scientific article published on 11 October 2011

Antiretroviral Therapy for the Prevention of HIV-1 Transmission

scientific article published on 18 July 2016

Antiretroviral treatment initiation among HIV-infected pregnant women with low CD4(+) cell counts in Gaborone, Botswana

scientific article

Association of HIV diversity and virologic outcomes in early antiretroviral treatment: HPTN 052.

scientific article

Barriers to antiretroviral adherence for patients living with HIV infection and AIDS in Botswana

scientific article

Birth weight for gestational age norms for a large cohort of infants born to HIV-negative women in Botswana compared with norms for U.S.-born black infants ⬇️

scientific article published on December 16, 2011

Botswana should consider expansion of free antiretroviral therapy to immigrants.

scientific article published in June 2019

Botswana's progress toward achieving the 2020 UNAIDS 90-90-90 antiretroviral therapy and virological suppression goals: a population-based survey

scientific article published on 24 March 2016

Breastfeeding plus infant zidovudine prophylaxis for 6 months vs formula feeding plus infant zidovudine for 1 month to reduce mother-to-child HIV transmission in Botswana: a randomized trial: the Mashi Study

scientific article published on August 2006

Brief Report: HIV Drug Resistance in Adults Failing Early Antiretroviral Treatment: Results From the HIV Prevention Trials Network 052 Trial

scientific article published on 08 February 2016

Brief Report: High Sensitivity and Specificity of the Cepheid Xpert HIV-1 Qualitative Point-of-Care Test Among Newborns in Botswana

scientific article published on 24 March 2017

Characteristics of HIV-1 discordant couples enrolled in a trial of HSV-2 suppression to reduce HIV-1 transmission: the partners study

scientific article

Comparative Safety of Antiretroviral Treatment Regimens in Pregnancy

scientific article published on 07 August 2017

Comparative safety of dolutegravir-based or efavirenz-based antiretroviral treatment started during pregnancy in Botswana: an observational study

scientific article published on 04 June 2018

Correction for Novitsky et al., Long-Range HIV Genotyping Using Viral RNA and Proviral DNA for Analysis of HIV Drug Resistance and HIV Clustering

scientific article published on April 2016

Correction: Features of Recently Transmitted HIV-1 Clade C Viruses that Impact Antibody Recognition: Implications for Active and Passive Immunization

scientific article published on 25 September 2017

Correction: Immunological non-response and low hemoglobin levels are predictors of incident tuberculosis among HIV-infected individuals on Truvada-based therapy in Botswana.

scientific article

Cotrimoxazole prophylaxis was associated with enteric commensal bacterial resistance among HIV-exposed infants in a randomized controlled trial, Botswana

scientific article

Cross-sectional estimates revealed high HIV incidence in Botswana rural communities in the era of successful ART scale-up in 2013-2015

scientific article published in PLoS ONE

Daily acyclovir for HIV-1 disease progression in people dually infected with HIV-1 and herpes simplex virus type 2: a randomised placebo-controlled trial

scientific article

Detecting congenital malformations - Lessons learned from the Mpepu study, Botswana

scientific article

Effect of Gestational Age at Tenofovir-Emtricitabine-Efavirenz Initiation on Adverse Birth Outcomes in Botswana

scientific article published on 23 April 2018

Effect of co-trimoxazole on mortality in HIV-exposed but uninfected children in Botswana (the Mpepu Study): a double-blind, randomised, placebo-controlled trial

scientific article published on May 2017

Effect of micronutrient supplementation on disease progression in asymptomatic, antiretroviral-naive, HIV-infected adults in Botswana: a randomized clinical trial

scientific article

Effects of early versus delayed initiation of antiretroviral treatment on clinical outcomes of HIV-1 infection: results from the phase 3 HPTN 052 randomised controlled trial

scientific article

Effects of in utero antiretroviral exposure on longitudinal growth of HIV-exposed uninfected infants in Botswana

scientific article

Emulating a target trial of antiretroviral therapy regimens started before conception and risk of adverse birth outcomes

scientific article published on 2 November 2017

Env sequence determinants in CXCR4-using human immunodeficiency virus type-1 subtype C.

scientific article published on 3 September 2012

Establishing and Delivering Quality Radiation Therapy in Resource-Constrained Settings: The Story of Botswana

scientific article

Estimated age and gender profile of individuals missed by a home-based HIV testing and counselling campaign in a Botswana community

scientific article published on 29 May 2015

Evaluation of the false recent classification rates of multiassay algorithms in estimating HIV type 1 subtype C incidence

scientific article published on 06 September 2013

Evolution of proviral gp120 over the first year of HIV-1 subtype C infection

scientific article

Evolutionary gamut of in vivo Gag substitutions during early HIV-1 subtype C infection

scientific article published on 19 October 2011

Extended high viremics: a substantial fraction of individuals maintain high plasma viral RNA levels after acute HIV-1 subtype C infection

scientific article published on July 2011

Features of Recently Transmitted HIV-1 Clade C Viruses that Impact Antibody Recognition: Implications for Active and Passive Immunization

scientific article

Genome-Wide Analyses Reveal Gene Influence on HIV Disease Progression and HIV-1C Acquisition in Southern Africa

scientific article published on 28 January 2017

HIV in the workplace in Botswana: incidence, prevalence, and disease severity

scientific article

HIV transmission and 24-month survival in a randomized trial of HAART to prevent MTCT during pregnancy and breastfeeding in Botswana

scientific article published on July 2013

HIV-1 subtype C-infected individuals maintaining high viral load as potential targets for the "test-and-treat" approach to reduce HIV transmission

scientific article

HIV-associated morbidity and mortality in a setting of high ART coverage: prospective surveillance results from a district hospital in Botswana

scientific article published on 01 December 2019

HIV-related mortality at a district hospital in Botswana

scientific article published on 9 May 2016

Herpes simplex virus type 2 suppressive therapy with acyclovir or valacyclovir does not select for specific HIV-1 resistance in HIV-1/HSV-2 dually infected persons

scientific article

High HIV-1 RNA among Newly Diagnosed People in Botswana

scientific article

High Prevalence of Hypertension and Placental Insufficiency, but No In Utero HIV Transmission, among Women on HAART with Stillbirths in Botswana ⬇️

scientific article published on February 22, 2012

High Proportion of Deaths Attributable to HIV Among Postpartum Women in Botswana Despite Widespread Uptake of Antiretroviral Therapy

scientific article published on January 2017

High Rates of Occult Hepatitis B Virus Infection in HIV-Positive Individuals Initiating Antiretroviral Therapy in Botswana

scientific article published on 13 September 2017

High incidence of tuberculosis in the first year of antiretroviral therapy in the Botswana National antiretroviral therapy programme between 2011 and 2015

scientific article published on 01 December 2019

High viral load and elevated angiogenic markers associated with increased risk of preeclampsia among women initiating highly active antiretroviral therapy in pregnancy in the Mma Bana study, Botswana

scientific article published on April 2013

Higher-than-expected rates of lactic acidosis among highly active antiretroviral therapy-treated women in Botswana: preliminary results from a large randomized clinical trial

scientific article

Highly active antiretroviral therapy and adverse birth outcomes among HIV-infected women in Botswana

scientific article

Highly active antiretroviral therapy versus zidovudine for prevention of mother-to-child transmission in a programmatic setting, Botswana

scientific article

Hiv Drug Resistance in Adults Receiving Early Versus Delayed Antiretroviral Therapy: Hptn 052.

scientific article published on 28 December 2017

Immunohaematological reference values for HIV-negative healthy adults in Botswana

scientific article published on January 2012

Immunohaematological reference values for HIV-negative healthy adults in Botswana

scientific article published on 15 December 2011

Immunological non-response and low hemoglobin levels are predictors of incident tuberculosis among HIV-infected individuals on Truvada-based therapy in Botswana

scientific article published on 31 January 2018

Implementation of Universal HIV Testing and Treatment to Reduce HIV Incidence in Botswana: the Ya Tsie Study

scientific article published on 14 August 2020

In Silico Analysis of Hepatitis B Virus Occult Associated Mutations in Botswana Using a Novel Algorithm

article

In utero exposure to antiretrovirals and neurodevelopment among HIV-exposed uninfected children in Botswana

scientific article published on 15 March 2018

In-utero triple antiretroviral exposure associated with decreased growth among HIV-exposed uninfected infants in Botswana

scientific article

Incidence of hepatitis B virus infection among human immunodeficiency virus-infected treatment naïve adults in Botswana

scientific article published on 01 February 2020

Increased Risk of Preterm Delivery Among HIV-Infected Women Randomized to Protease Versus Nucleoside Reverse Transcriptase Inhibitor–Based HAART During Pregnancy

article

Increased risk of preterm delivery among HIV-infected women randomized to protease versus nucleoside reverse transcriptase inhibitor-based HAART during pregnancy

scientific article

Increased risk of severe infant anemia after exposure to maternal HAART, Botswana

scientific article

Infant feeding practices were not associated with breast milk HIV-1 RNA levels in a randomized clinical trial in Botswana

scientific article

Infant morbidity, mortality, and breast milk immunologic profiles among breast-feeding HIV-infected and HIV-uninfected women in Botswana

scientific article published on 09 July 2007

LOW FALSE RECENT RATE OF LIMITING ANTIGEN AVIDITY ASSAY COMBINED WITH HIV-1 RNA DATA IN BOTSWANA

article

Lack of Virological Suppression Among Young HIV-Positive Adults in Botswana

article

Linear Growth Faltering Among HIV-Exposed Uninfected Children

scientific article published on 21 April 2016

Long-Range HIV Genotyping Using Viral RNA and Proviral DNA for Analysis of HIV Drug Resistance and HIV Clustering

scientific article published on 3 June 2015

Low rates of NRTI and NNRTI drug resistance among participants in the Botswana combination prevention program (BCPP) trial

scholarly article by Sikhulile Moyo et al published 7 February 2019 in AIDS

Low rates of nucleoside reverse transcriptase inhibitor and nonnucleoside reverse transcriptase inhibitor drug resistance in Botswana

scientific article published on 01 May 2019

Mapping of HIV-1C Transmission Networks Reveals Extensive Spread of Viral Lineages across Villages in Botswana Treatment-as-Prevention Trial

scientific article published on 03 June 2020

Maternal single-dose nevirapine versus placebo as part of an antiretroviral strategy to prevent mother-to-child HIV transmission in Botswana

scientific article

Minor resistant variants in nevirapine-exposed infants may predict virologic failure on nevirapine-containing ART.

scientific article

Molecular characterisation of hepatitis B virus in HIV-1 subtype C infected patients in Botswana

scientific article published on 13 August 2015

Neural-Tube Defects and Antiretroviral Treatment Regimens in Botswana

scientific article published on 22 July 2019

Neurodevelopment of HIV-Exposed and HIV-Unexposed Uninfected Children at 24 Months

scientific article published on 14 September 2017

No clinically significant drug-resistance mutations in HIV-1 subtype C-infected women after discontinuation of NRTI-based or PI-based HAART for PMTCT in Botswana

scientific article published on August 2013

Pairwise diversity and tMRCA as potential markers for HIV infection recency

scientific article published on February 2017

Perceptions of couple HIV counseling and testing in Botswana: a stakeholder analysis

scientific article

Persistently elevated serum interleukin-6 predicts mortality among adults receiving combination antiretroviral therapy in Botswana: results from a clinical trial

scientific article published on 09 May 2013

Phylogenetic methods inconsistently predict direction of HIV transmission among heterosexual pairs in the HPTN052 cohort

article

Phylogenetic relatedness of circulating HIV-1C variants in Mochudi, Botswana

scientific article

Plasma Cytokine Levels in Chronic Asymptomatic HIV-1 Subtype C Infection as an Indicator of Disease Progression in Botswana: A Retrospective Case Control Study

scientific article published on 28 September 2015

Point-of-Care Cepheid Xpert HIV-1 Viral Load Test in Rural African Communities Is Feasible and Reliable

scientific article published on 12 October 2016

Population uptake of HIV testing, treatment, viral suppression, and male circumcision following a community-based intervention in Botswana (Ya Tsie/BCPP): a cluster-randomised trial

scientific article published on 01 June 2020

Pre-clinical carotid atherosclerosis and sCD163 among virally suppressed HIV patients in Botswana compared with uninfected controls

scientific article

Predictors of early breastfeeding cessation among HIV-infected women in Botswana

scientific article

Pregnancy rates and birth outcomes among women on efavirenz-containing highly active antiretroviral therapy in Botswana

scientific article

Prevalence and clinical associations of CXCR4-using HIV-1 among treatment-naive subtype C-infected women in Botswana

scientific article

Prevalence and molecular characterization of Hepatitis B in HIV infected individuals in Botswana

article

Prevalence of Rilpivirine and Etravirine Resistance Mutations in HIV-1 Subtype C-Infected Patients Failing Nevirapine or Efavirenz-Based Combination Antiretroviral Therapy in Botswana

scientific article published on 12 June 2018

Prevalence of human papillomavirus genotypes and associated cervical squamous intraepithelial lesions in HIV-infected women in Botswana

scientific article

Prevention of HIV-1 infection with early antiretroviral therapy

scientific article

Reassuring Birth Outcomes With Tenofovir/Emtricitabine/Efavirenz Used for Prevention of Mother-to-Child Transmission of HIV in Botswana

scientific article published on 12 September 2015

Recruitment, Follow-Up and Characteristics of HIV Infected Adults who Use Illicit Drugs in Southern Africa.

scientific article published on 8 December 2015

Regional differences in prevalence of HIV-1 discordance in Africa and enrollment of HIV-1 discordant couples into an HIV-1 prevention trial

scientific article

Response to antiretroviral therapy after a single, peripartum dose of nevirapine

scientific article

Response to zidovudine/didanosine-containing combination antiretroviral therapy among HIV-1 subtype C-infected adults in Botswana: two-year outcomes from a randomized clinical trial

scientific article

Risk factors for early and late transmission of HIV via breast-feeding among infants born to HIV-infected women in a randomized clinical trial in Botswana

scientific article published on February 2009

Risk factors for very preterm delivery and delivery of very‐small‐for‐gestational‐age infants among HIV‐exposed and HIV‐unexposed infants in Botswana ⬇️

scientific article published on July 20, 2011

Self-reported risky sexual practices among adolescents and young adults in Botswana

scientific article published on 26 June 2019

Short Communication: Low False Recent Rate of Limiting Antigen-Avidity Assay Combined with HIV-1 RNA Data in Botswana

scientific article

Short communication: effect of short-course antenatal zidovudine and single-dose nevirapine on the BED capture enzyme immunoassay levels in HIV type 1 subtype C infection

scientific article published on 19 April 2013

Similar HIV protection from four weeks of zidovudine versus nevirapine prophylaxis among formula-fed infants in Botswana.

scientific article published on 28 March 2018

Single-arm evaluation of the AccuCirc device for early infant male circumcision in Botswana

scientific article published on May 2014

Slow CD4+ T-Cell Recovery in Human Immunodeficiency Virus/Hepatitis B Virus-Coinfected Patients Initiating Truvada-Based Combination Antiretroviral Therapy in Botswana

scientific article published on 16 August 2016

Strengthening healthcare capacity through a responsive, country-specific, training standard: the KITSO AIDS training program's support of Botswana's national antiretroviral therapy rollout

scientific article published on 29 February 2008

Targeted HIV testing at birth supported by low and predictable mother-to-child transmission risk in Botswana.

scientific article published in May 2018

Temporal reduction of HIV type 1 viral load in breast milk by single-dose nevirapine during prevention of MTCT

scientific article

The Impact of Human Pegivirus on CD4 Cell Count in HIV-Positive Persons in Botswana

scientific article published on 10 October 2017

The aetiology of diarrhoea, pneumonia and respiratory colonization of HIV-exposed infants randomized to breast- or formula-feeding

scientific article

The effect of micronutrient supplementation on active TB incidence early in HIV infection in Botswana

scientific article published on 14 July 2017

Therapeutic levels of lopinavir in late pregnancy and abacavir passage into breast milk in the Mma Bana Study, Botswana

scientific article

Timing constraints of in vivo gag mutations during primary HIV-1 subtype C infection

scientific article

Undetectable proviral deoxyribonucleic acid in an adolescent perinatally infected with human immunodeficiency virus-1C and on long-term antiretroviral therapy resulted in viral rebound following antiretroviral therapy termination: A case report with

scientific article published on 01 November 2019

Undisclosed antiretroviral drug use in Botswana: implication for national estimates

article

Undisclosed antiretroviral drug use in a multinational clinical trial (HIV Prevention Trials Network 052).

scientific article published on August 2013

Unintended pregnancy, contraceptive use, and childbearing desires among HIV-infected and HIV-uninfected women in Botswana: across-sectional study

scientific article published on 16 January 2016

Universal Testing and Treatment for HIV Infection in Botswana. Reply

scientific article published on 01 November 2019

Universal Testing, Expanded Treatment, and Incidence of HIV Infection in Botswana

scientific article published on 01 July 2019

Validation of A Point-of-Care Lactate Device For Screening At-Risk Adults Receiving Combination Antiretroviral Therapy In Botswana

scientific article

Viral load and CD4+ T-cell dynamics in primary HIV-1 subtype C infection.

scientific article published on January 2009

Vitamin D insufficiency in HIV-infected pregnant women receiving antiretroviral therapy is not associated with morbidity, mortality or growth impairment in their uninfected infants in Botswana

scientific article

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