Search filters

List of works by Paolo Ubezio

A biodistribution study of PEGylated PCL-based nanoparticles in C57BL/6 mice bearing B16/F10 melanoma.

scientific article

A generalised age- and phase-structured model of human tumour cell populations both unperturbed and exposed to a range of cancer therapies.

scientific article published on 15 March 2007

A mathematical model of the effect of aging on bone marrow cells colonizing the thymus.

scientific article published in February 1993

A methyl methacrylate-HEMA-CL(n) copolymerization investigation: from kinetics to bioapplications.

scientific article

A specific miRNA signature correlates with complete pathological response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer.

scientific article

ActivinA: a new leukemia-promoting factor conferring migratory advantage to B-cell precursor-acute lymphoblastic leukemic cells

scientific article published on 27 September 2018

Application of 3D Mass Spectrometry Imaging to TKIs

scientific article

Beyond The T/C Ratio: Old And New Anticancer Activity Scores In Vivo

scientific article published on 19 September 2019

Biochemical, morphological and flow-cytometric evaluation of the effects of hexachlorobenzene on rat liver

scientific article published on 01 April 1990

Calpain as a multi-site regulator of cell cycle.

scientific article published in April 2004

Cediranib combined with chemotherapy reduces tumor dissemination and prolongs the survival of mice bearing patient-derived ovarian cancer xenografts with different responsiveness to cisplatin.

scientific article published on 17 July 2015

Cell cycle simulation for flow cytometry.

scientific article published in March 1990

Cell killing and resistance in pre-operative breast cancer chemotherapy

scientific article published on 21 July 2008

Cell kinetics of human ovarian cancer with in vivo administration of bromodeoxyuridine

scientific article published on 01 September 1994

Cell loss and the concept of potential doubling time ⬇️

scientific article published on September 1, 1997

Cellular and molecular determinants of all-trans retinoic acid sensitivity in breast cancer: Luminal phenotype and RARα expression

scientific article published on 17 April 2015

Characterization of cyclin B1 expression in human cancer cell lines by a new three-parameter BrdUrd/cyclin B1/DNA analysis

scientific article published on 01 January 1998

Combination of PPARγ Agonist Pioglitazone and Trabectedin Induce Adipocyte Differentiation to Overcome Trabectedin Resistance in Myxoid Liposarcomas

scientific article published on 03 September 2019

Combination of the new minor groove alkylator tallimustine and melphalan

scientific article published in February 1997

Combination of trabectedin and irinotecan is highly effective in a human rhabdomyosarcoma xenograft

scientific article published on September 2005

Comparison of histone variant synthesis in human lymphocytic leukemia cells and in normal lymphocytes

scientific article published on 01 July 1988

Cytologic and flow cytometric DNA analysis of multinucleated tumor cells and derived microcells

scientific article published on 01 February 1989

DNA damage, cytotoxic effect and cell-cycle perturbation of Hoechst 33342 on L1210 cells in vitro ⬇️

scientific article published on January 1, 1988

Doxorubicin and m-AMSA induced DNA damage in blast cells from AML patients

scientific article published on 01 January 1991

Dynamic rendering of the heterogeneous cell response to anticancer treatments

scientific article (publication date: 2013)

Dynamics of cell cycle phase perturbations by trabectedin (ET-743) in nucleotide excision repair (NER)-deficient and NER-proficient cells, unravelled by a novel mathematical simulation approach.

scientific article

Effective combination of ET-743 and doxorubicin in sarcoma: preclinical studies

scientific article published on 29 May 2003

Enhanced cell cycle perturbation and apoptosis mediate the synergistic effects of ST1926 and ATRA in neuroblastoma preclinical models

scientific article published on 3 June 2011

Fate of PLA and PCL-Based Polymeric Nanocarriers in Cellular and Animal Models of Triple-Negative Breast Cancer.

scientific article published on 20 January 2016

Flow-cytometric analysis of DNA distribution after VP16-213 treatment of Lewis lung carcinoma

scientific article published on 01 January 1983

From flow cytometric BrdUrd data to cell population growth and doubling time ⬇️

scientific article published on November 1, 1997

Genotoxic damage induced by doxorubicin in two human melanoma cell lines

scientific article published on 01 October 1987

HER2-positive breast-cancer cell lines are sensitive to KDM5 inhibition: definition of a gene-expression model for the selection of sensitive cases

scientific article published on 11 December 2018

Heterogeneous cell response to topotecan in a CFSE-based proliferation test.

scientific article

Histone H1(0) is synthesized by human lymphocytic leukemia cells but not by normal lymphocytes

scientific article published on 01 October 1987

In vivo measurement of vascular modulation in experimental tumors using a fluorescent contrast agent

scientific article published on 12 April 2008

Increasing 1-beta-D-arabinofuranosylcytosine efficacy by scheduled dosing intervals based on direct measurements of bone marrow cell kinetics

scientific article published on 15 December 1994

Inhibition of SIRT2 potentiates the anti-motility activity of taxanes: implications for antineoplastic combination therapies.

scientific article

Integrated experimental and simulation study of the response to sequential treatment with erlotinib and gemcitabine in pancreatic cancer.

scientific article published on 19 February 2016

Integrated multiplatform method for in vitro quantitative assessment of cellular uptake for fluorescent polymer nanoparticles.

scientific article published on January 2014

Interoperability of time series cytometric data: a cross platform approach for modeling tumor heterogeneity.

scientific article

Interpreting cell cycle effects of drugs: the case of melphalan.

scientific article published on 30 September 2005

Intracellular doxorubicin concentrations and drug-induced DNA damage in a human colon adenocarcinoma cell line and in a drug-resistant subline.

scientific article published in December 1988

Intracellular drug concentration and DNA damage in human childhood leukemic cells exposed to doxorubicin

scientific article published on 01 May 1988

Intracellular glutathione heterogeneity in L1210 murine leukemia sublines made resistant to DNA-interacting anti-neoplastic agents.

scientific article published on May 1993

Kinetic heterogeneity of an experimental tumour revealed by BrdUrd incorporation and mathematical modelling.

scientific article published on March 2002

Measuring the complexity of cell cycle arrest and killing of drugs: kinetics of phase-specific effects induced by taxol

scientific article published on 01 October 1999

Microcomputer experience in analysis of flow cytometric DNA distributions

scientific article published on 01 January 1985

Miniaturizing bromodeoxyuridine incorporation enables the usage of flow cytometry for cell cycle analysis of adherent tissue culture cells for high throughput screening.

scientific article published on 8 September 2010

Modeling Cytostatic and Cytotoxic Responses to New Treatment Regimens for Ovarian Cancer

scientific article published on 26 September 2017

Modeling of non-small cell lung cancer volume changes during CT-based image guided radiotherapy: patterns observed and clinical implications

scientific article published on 24 October 2013

Modelling the balance between quiescence and cell death in normal and tumour cell populations.

scientific article published on 28 March 2006

PEGylated Nanoparticles Obtained through Emulsion Polymerization as Paclitaxel Carriers

scientific article published in December 2015

Past-in-the-Future. Peak detection improves targeted mass spectrometry imaging

scientific article published on 28 June 2018

Pharmacokinetics and antineoplastic activity of galectin-1-targeting OTX008 in combination with sunitinib.

scientific article published on 24 August 2013

Promising in vivo efficacy of the BET bromodomain inhibitor OTX015/MK-8628 in malignant pleural mesothelioma xenografts

scientific article published on 4 September 2016

Quality control study of the Italian Group of Cytometry on flow cytometry DNA content measurements: II. Factors affecting inter- and intralaboratory variability

scientific article published on 01 April 1997

Representing cell cycle data.

scientific article

Retinoic Acid Sensitivity of Triple-Negative Breast Cancer Cells Characterized by Constitutive Activation of the notch1 Pathway: The Role of Rarβ

scientific article published on 18 October 2020

Self-Assembling PCL-Based Nanoparticles as PTX Solubility Enhancer Excipients

scientific article published on 25 July 2018

Sensitivity of flow cytometric data to variations in cell cycle parameters.

scientific article

Small interfering RNA delivery through positively charged polymer nanoparticles.

scientific article published on 18 February 2016

Solar UV radiation: differential effectiveness of UVB subcomponents in causing cell death, micronucleus induction and delayed expression of heritable damage in human hybrid cells.

scientific article

Synthesis of surfactant free PCL-PEG brushed nanoparticles with tunable degradation kinetics.

scientific article published on 21 June 2013

The antitumor efficacy of cytotoxic drugs is potentiated by treatment with PNU 145156E, a growth-factor-complexing molecule

scientific article published on 01 January 1999

The contribution of p53 in the dynamics of cell cycle response to DNA damage interpreted by a mathematical model.

scientific article published on 2 April 2007

The vascular targeting property of paclitaxel is enhanced by SU6668, a receptor tyrosine kinase inhibitor, causing apoptosis of endothelial cells and inhibition of angiogenesis

scientific article published on March 2006

Time- and dose-dependence of DNA fragmentation induced by anticancer agents: a flow cytometric study

scientific article published on 01 January 1997

Tumor progression and metastatic dissemination in ovarian cancer after dose-dense or conventional paclitaxel and cisplatin plus bevacizumab

scientific article published on 07 August 2018

[Anthracycline resistance: cytofluorometric study on infantile lymphoblastic leukemia]

scientific article

Paulina is supported by:

About Paulina

Help