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List of works by Joseph Fontana

4-[3-(5,6,7,8-Tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)phenyl]benzoic acid and heterocyclic-bridged analogues are novel retinoic acid receptor subtype and retinoid X receptor alpha agonists

scientific article published on 01 June 2000

A phase II trial of gefitinib in patients with non-metastatic hormone-refractory prostate cancer

scientific article published in October 2007

A single institution experience with concurrent capecitabine and radiation therapy in weak and/or elderly patients with urothelial cancer

scientific article published in August 2005

Adamantyl Retinoid-Related Molecules Induce Apoptosis in Pancreatic Cancer Cells by Inhibiting IGF-1R and Wnt/β-Catenin Pathways.

scientific article published on 5 April 2012

Adamantyl-substituted retinoid-related molecules bind small heterodimer partner and modulate the Sin3A repressor.

scientific article

Adamantyl-substituted retinoid-related molecules induce apoptosis in human acute myelogenous leukemia cells.

scientific article published on 9 November 2010

An active regimen of weekly paclitaxel and estramustine in metastatic androgen-independent prostate cancer.

scientific article published in December 2002

An adamantyl-substituted retinoid-derived molecule that inhibits cancer cell growth and angiogenesis by inducing apoptosis and binds to small heterodimer partner nuclear receptor: effects of modifying its carboxylate group on apoptosis, proliferatio

scientific article published on 10 May 2007

Analogues of orphan nuclear receptor small heterodimer partner ligand and apoptosis inducer (E)-4-[3-(1-adamantyl)-4-hydroxyphenyl]-3-chlorocinnamic acid. 2. Impact of 3-chloro group replacement on inhibition of proliferation and induction of apopto

scientific article

Apoptosis induction by a novel retinoid-related molecule requires nuclear factor-kappaB activation.

scientific article published on June 2005

Apoptosis signaling by the novel compound 3-Cl-AHPC involves increased EGFR proteolysis and accompanying decreased phosphatidylinositol 3-kinase and AKT kinase activities.

scientific article published on March 2004

Bcl-X(L) expression and its downregulation by a novel retinoid in breast carcinoma cells

scientific article published on 01 April 1997

Differential distribution of protein phosphatase 2A in human breast carcinoma cell lines and its relation to estrogen receptor status.

scientific article published on March 1999

Elevated expression of retinoic acid receptor-alpha (RAR alpha) in estrogen-receptor-positive breast carcinomas as detected by immunohistochemistry

scientific article published on 01 February 1997

Gene amplification and transcriptional upregulation of the sarco/endoplasmic reticulum Ca2+ transport ATPase in thapsigargin-resistant hamster smooth muscle cells.

scientific article published on October 1998

Genistein inhibits proliferation similarly in estrogen receptor-positive and negative human breast carcinoma cell lines characterized by P21WAF1/CIP1 induction, G2/M arrest, and apoptosis

scientific article published on 01 April 1998

Heteroatom-substituted analogues of orphan nuclear receptor small heterodimer partner ligand and apoptosis inducer (E)-4-[3-(1-Adamantyl)-4-hydroxyphenyl]-3-chlorocinnamic acid.

scientific article published on 6 May 2011

Identification and characterization of a cell cycle and apoptosis regulatory protein-1 as a novel mediator of apoptosis signaling by retinoid CD437

scientific article (publication date: 29 August 2003)

Identification and characterization of novel AML1-ETO fusion transcripts in pediatric t(8;21) acute myeloid leukemia: a report from the Children's Oncology Group.

scientific article published on 12 May 2008

Induction of apoptosis in retinoid-refractory acute myelogenous leukemia by a novel AHPN analog.

scientific article published on 31 July 2003

Maximal adamantyl-substituted retinoid-related molecule-induced apoptosis requires NF-κB noncanonical and canonical pathway activation

scientific article published on 30 July 2010

Neo-adjuvant chemotherapy for operable breast cancer induces apoptosis

scientific article published on 01 February 1999

Neoadjuvant docetaxel and estramustine chemotherapy in high-risk/locally advanced prostate cancer.

scientific article published in April 2003

Phase II trial of bevacizumab and satraplatin in docetaxel-pretreated metastatic castrate-resistant prostate cancer

scientific article

Post-transcriptional regulation of the DNA damage-inducible gadd45 gene in human breast carcinoma cells exposed to a novel retinoid CD437.

scientific article published on August 1999

Preclinical efficacy evaluations of XK-469: dose schedule, route and cross-resistance behavior in tumor bearing mice.

scientific article published in February 2002

Retinoic acid inhibition of insulin-like growth factor I stimulation of c-fos mRNA levels in a breast carcinoma cell line.

scientific article published on March 1994

Retinoid Signaling in Breast Carcinoma Cells

scientific article published on 01 April 2003

Secretion and binding of transforming growth factor beta by scleroderma and normal dermal fibroblasts.

scientific article published on May 1990

Significance of Apoptosis and Apoptotic-Related Proteins, Bcl-2, and Bax in Primary Breast Cancer.

scientific article published in January 2000

Synthetic retinoid CD437 induces S-phase arrest and apoptosis in human prostate cancer cells LNCaP and PC-3

scientific article published on 01 February 1999

The peptidomimetic, 1-adamantyl-substituted, and flex-het classes of retinoid-derived molecules: structure-activity relationships and retinoid receptor-independent anticancer activities.

scientific article published on June 2010

Thyroid hormone enhancement of estradiol stimulation of breast carcinoma proliferation

scientific article published on 01 May 1995

Transformed human bronchial epithelial cells (BEAS-2B) alter the growth and morphology of normal human bronchial epithelial cells in vitro.

scientific article published on October 1990

Upregulation of miR-150* and miR-630 induces apoptosis in pancreatic cancer cells by targeting IGF-1R.

scientific article

p21/waf1/cip1 and mdm-2 expression in breast carcinoma patients as related to prognosis

scientific article published on 01 October 1997