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List of works by Christian Koelsche

AKT1E17K mutations cluster with meningothelial and transitional meningiomas and can be detected by SFRP1 immunohistochemistry

scientific article published on 6 October 2013

ATRX and IDH1-R132H immunohistochemistry with subsequent copy number analysis and IDH sequencing as a basis for an "integrated" diagnostic approach for adult astrocytoma, oligodendroglioma and glioblastoma

scientific article published on 27 November 2014

Adult IDH wild type astrocytomas biologically and clinically resolve into other tumor entities

scientific article published on 19 June 2015

Aggressive Hematopoietic Malignancy Characterized by Biallelic Loss of SMARCB1

scientific article published on 28 October 2020

Anaplastic astrocytoma with piloid features, a novel molecular class of IDH wildtype glioma with recurrent MAPK pathway, CDKN2A/B and ATRX alterations

scientific article published on 21 March 2018

Array-based DNA-methylation profiling in sarcomas with small blue round cell histology provides valuable diagnostic information

scientific article published on 23 March 2018

BRAF-mutated pleomorphic xanthoastrocytoma is associated with temporal location, reticulin fiber deposition and CD34 expression.

scientific article

CIC and FUBP1 mutations in oligodendrogliomas, oligoastrocytomas and astrocytomas

scientific article published on 17 May 2012

Clinicopathologic and molecular features of intracranial desmoplastic small round cell tumors

scientific article published on 29 December 2019

Copy number variation analysis and methylome profiling of a GNAQ-mutant primary meningeal melanocytic tumor and its liver metastasis.

scientific article published on 11 December 2016

DNA Methylation Profiling Identifies Distinct Clusters in Angiosarcomas

scientific article published on 27 September 2019

DNA methylation profiling distinguishes Ewing-like sarcoma with EWSR1-NFATc2 fusion from Ewing sarcoma

scientific article published on 20 March 2019

DNA methylation-based classification and grading system for meningioma: a multicentre, retrospective analysis

scientific article published on 14 March 2017

DNA methylation-based classification of central nervous system tumours

scientific article published on 14 March 2018

DNA methylation-based profiling of uterine neoplasms: a novel tool to improve gynecologic cancer diagnostics

scientific article published on 25 November 2019

DNA methylation-based reclassification of olfactory neuroblastoma

scientific article published on 05 May 2018

Differential nuclear ATRX expression in sarcomas

scientific article published on 20 August 2015

Distribution of TERT promoter mutations in pediatric and adult tumors of the nervous system

scientific article published on 24 October 2013

Do Increased Doses to Stem-Cell Niches during Radiation Therapy Improve Glioblastoma Survival?

scientific article published on 27 June 2016

FGFR1:TACC1 fusion is a frequent event in molecularly defined extraventricular neurocytoma.

scientific article

Farewell to oligoastrocytoma: in situ molecular genetics favor classification as either oligodendroglioma or astrocytoma

scientific article published on 21 August 2014

Gain of 12p encompassing CCND2 is associated with gemistocytic histology in IDH mutant astrocytomas

scientific article published on 20 December 2016

Histone 3.3 hotspot mutations in conventional osteosarcomas: a comprehensive clinical and molecular characterization of six H3F3A mutated cases

scientific article

IDH mutant diffuse and anaplastic astrocytomas have similar age at presentation and little difference in survival: a grading problem for WHO.

scientific article published on 12 May 2015

Integrated DNA methylation and copy-number profiling identify three clinically and biologically relevant groups of anaplastic glioma

scientific article published on 10 July 2014

Integrated Genomic Classification of Melanocytic Tumors of the Central Nervous System Using Mutation Analysis, Copy Number Alterations, and DNA Methylation Profiling

scientific article published on 11 June 2018

Intracranial mesenchymal tumors with FET-CREB fusion are composed of at least two epigenetic subgroups distinct from meningioma and extracranial sarcomas

scholarly article

Isomorphic diffuse glioma is a morphologically and molecularly distinct tumour entity with recurrent gene fusions of MYBL1 or MYB and a benign disease course

scientific article published on 28 September 2019

Melanotic tumors of the nervous system are characterized by distinct mutational, chromosomal and epigenomic profiles

scientific article published on 15 December 2014

Meningeal hemangiopericytoma and solitary fibrous tumors carry the NAB2-STAT6 fusion and can be diagnosed by nuclear expression of STAT6 protein

scientific article published on 11 April 2013

Methylation-based classification of benign and malignant peripheral nerve sheath tumors

scientific article published on 8 February 2016

New Brain Tumor Entities Emerge from Molecular Classification of CNS-PNETs

scientific article

Next-generation sequencing in routine brain tumor diagnostics enables an integrated diagnosis and identifies actionable targets

scientific article published on 15 December 2015

Novel, improved grading system(s) for IDH-mutant astrocytic gliomas

scientific article published on 23 April 2018

Nuclear relocation of STAT6 reliably predicts NAB2-STAT6 fusion for the diagnosis of solitary fibrous tumour

scientific article

Papillary glioneuronal tumor (PGNT) exhibits a characteristic methylation profile and fusions involving PRKCA

scientific article published on 13 February 2019

Practical implementation of DNA methylation and copy-number-based CNS tumor diagnostics: the Heidelberg experience.

scientific article

Primary intracranial spindle cell sarcoma with rhabdomyosarcoma-like features share a highly distinct methylation profile and DICER1 mutations.

scientific article

Primary pulmonary myxoid sarcoma with an unusual gene fusion between exon 7 of EWSR1 and exon 5 of CREB1

scientific article published on 27 November 2019

Recurrent intragenic rearrangements of EGFR and BRAF in soft tissue tumors of infants.

scientific article published on 18 June 2018

Routine RNA sequencing of formalin-fixed paraffin-embedded specimens in neuropathology diagnostics identifies diagnostically and therapeutically relevant gene fusions

scientific article published on 05 July 2019

Sarcoma classification by DNA methylation profiling

scientific article published on 21 January 2021

Sclerosing epithelioid mesenchymal neoplasm of the pancreas - a proposed new entity

scientific article published on 05 August 2019

Secretory meningiomas are defined by combined KLF4 K409Q and TRAF7 mutations

scientific article

TERT Promoter Mutations and Risk of Recurrence in Meningioma

scientific article published on 13 December 2015

TERT promoter mutations are highly recurrent in SHH subgroup medulloblastoma

scientific article published on 31 October 2013

Tumors diagnosed as cerebellar glioblastoma comprise distinct molecular entities

scientific article published on 28 October 2019