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List of works by Jørgen Frøkiær

A current view of the mammalian aquaglyceroporins.

scientific article published on January 2008

A novel method of ligand peptidomics to identify peptide ligands binding to AQP2-expressing plasma membranes and intracellular vesicles of rat kidney

scientific article

AQP3, p-AQP2, and AQP2 expression is reduced in polyuric rats with hypercalcemia: prevention by cAMP-PDE inhibitors

scientific article published on 30 July 2002

AQP7 is localized in capillaries of adipose tissue, cardiac and striated muscle: implications in glycerol metabolism

scientific article published on 31 October 2006

AQP9 expression in glioblastoma multiforme tumors is limited to a small population of astrocytic cells and CD15(+)/CalB(+) leukocytes.

scientific article

AT1 receptor blockade prevents interstitial and glomerular apoptosis but not fibrosis in pigs with neonatal induced partial unilateral ureteral obstruction

scientific article published on 13 March 2007

Acute growth hormone administration induces antidiuretic and antinatriuretic effects and increases phosphorylation of NKCC2.

scientific article published on 24 October 2006

Acute kidney injury in rats with or without pre-existing chronic kidney disease: Cytokine/chemokine response

scientific article published on 01 July 2014

Adenocaine and Mg(2+) reduce fluid requirement to maintain hypotensive resuscitation and improve cardiac and renal function in a porcine model of severe hemorrhagic shock*.

scientific article published in November 2012

Age-dependent renal expression of acid-base transporters in neonatal ureter obstruction

scientific article published on 03 June 2009

Age-related changes in expression in renal AQPs in response to congenital, partial, unilateral ureteral obstruction in rats.

scientific article published on 25 October 2011

Aldosterone increases urine production and decreases apical AQP2 expression in rats with diabetes insipidus

scientific article

Aldosterone-mediated apical targeting of ENaC subunits is blunted in rats with streptozotocin-induced diabetes mellitus

scientific article published on 19 November 2007

Altered expression of COX-1, COX-2, and mPGES in rats with nephrogenic and central diabetes insipidus

scientific article published on 11 January 2005

Altered expression of epithelial sodium channel in rats with bilateral or unilateral ureteral obstruction

scientific article published on 02 May 2007

Altered expression of major renal Na transporters in rats with bilateral ureteral obstruction and release of obstruction

scientific article published on 15 July 2003

Altered expression of major renal Na transporters in rats with unilateral ureteral obstruction

scientific article published on 21 August 2002

Altered expression of renal NHE3, TSC, BSC-1, and ENaC subunits in potassium-depleted rats

scientific article published on 30 July 2002

Altered expression of renal acid-base transporters in rats with lithium-induced NDI

scientific article published on 26 August 2003

Altered expression of selected genes in kidney of rats with lithium-induced NDI.

scientific article

Altered expression of urea transporters in response to ureteral obstruction

scientific article published on 24 February 2004

Angiotensin II AT1 receptor blockade decreases vasopressin-induced water reabsorption and AQP2 levels in NaCl-restricted rats

scientific article published on 7 December 2004

Angiotensin II mediates downregulation of aquaporin water channels and key renal sodium transporters in response to urinary tract obstruction

scientific article published on 06 June 2006

Angiotensin II regulates V2 receptor and pAQP2 during ureteral obstruction

scientific journal article

Aquaporin-9 and urea transporter-A gene deletions affect urea transmembrane passage in murine hepatocytes

scientific article published on 4 October 2012

Aquaporins in the kidney.

scientific article published on January 2009

Arterial Clamping Increases Central Renal Cryoablation Efficacy: An Animal Study

scientific article published on 25 August 2016

Automatic extraction of forward stroke volume using dynamic PET/CT: a dual-tracer and dual-scanner validation in patients with heart valve disease.

scientific article

Axial heterogeneity in basolateral AQP2 localization in rat kidney: effect of vasopressin

scientific article published on 26 November 2002

Bidirectional regulation of AQP2 trafficking and recycling: involvement of AQP2-S256 phosphorylation

scientific article published on 29 December 2004

Bilateral ureteral obstruction induces early downregulation and redistribution of AQP2 and phosphorylated AQP2.

scientific article

Biphasic effects of ANP infusion in conscious, euvolumic rats: roles of AQP2 and ENaC trafficking.

scientific article published on 20 September 2005

COX-2 activity transiently contributes to increased water and NaCl excretion in the polyuric phase after release of ureteral obstruction.

scientific article published on 16 January 2007

COX-2 disruption leads to increased central vasopressin stores and impaired urine concentrating ability in mice

scientific article

COX-2 inhibition prevents downregulation of key renal water and sodium transport proteins in response to bilateral ureteral obstruction.

scientific article

Candesartan prevents long-term impairment of renal function in response to neonatal partial unilateral ureteral obstruction

scientific article

Changes in cellular composition of kidney collecting duct cells in rats with lithium-induced NDI ⬇️

scientific article published on November 12, 2003

Changes of renal AQP2, ENaC, and NHE3 in experimentally induced heart failure: response to angiotensin II AT1 receptor blockade ⬇️

scientific article

Chitosan/siRNA nanoparticles targeting cyclooxygenase type 2 attenuate unilateral ureteral obstruction-induced kidney injury in mice.

scientific article

Chronic metabolic acidosis upregulates rat kidney Na-HCO cotransporters NBCn1 and NBC3 but not NBC1

scientific journal article

Citrate NMR peak irreproducibility in blood samples after reacquisition of spectra

scientific article published on 19 December 2019

Collecting duct expression of N-methyl-D-aspartate receptor subtype NR3a regulates urinary concentrating capacity

scientific article published on 04 May 2011

Compromised cardiac function in exercising teenagers with pectus excavatum

scientific article published on 25 July 2011

Correlation Between AVPR2 Mutations and Urinary AQP2 Excretion in Patients with Nephrogenic Diabetes Insipidus

scientific article published on 01 April 2007

Cyclooxygenase 2 inhibition exacerbates AQP2 and pAQP2 downregulation independently of V2 receptor abundance in the postobstructed kidney

scientific article published on 27 January 2010

Decreased expression of AQP2 and AQP4 water channels and Na,K-ATPase in kidney collecting duct in AQP3 null mice

scientific article published on 01 October 2005

Detecting reduced renal function in children: comparison of GFR-models and serum markers.

scientific article published on 4 September 2012

Disruption of cyclooxygenase type 2 exacerbates apoptosis and renal damage during obstructive nephropathy

scientific article

Disruption of cyclooxygenase-2 prevents downregulation of cortical AQP2 and AQP3 in response to bilateral ureteral obstruction in the mouse

scientific article published on 07 March 2012

Downregulation of renal aquaporins in response to unilateral ureteral obstruction

scientific article published on 07 January 2003

Dysregulation of renal aquaporins and epithelial sodium channel in lithium-induced nephrogenic diabetes insipidus

scientific article published on May 2008

E3 ubiquitin-protein ligases in rat kidney collecting duct: response to vasopressin stimulation and withdrawal ⬇️

scientific article published on July 6, 2011

Edelman's equation is valid in acute hyponatremia in a porcine model: plasma sodium concentration is determined by external balances of water and cations

scientific article published on 28 October 2009

Effect of remote ischemic conditioning on myocardial perfusion in patients with suspected ischemic coronary artery disease

scientific article published on 01 November 2016

Effects of alpha-lipoic acid on ischemia-reperfusion-induced renal dysfunction in rats

scientific article published on 21 November 2007

Epidermal growth factor and monocyte chemotactic peptide-1: Potential biomarkers of urinary tract obstruction in children with hydronephrosis

scientific article published on 08 December 2012

Erratum to: Evaluation of ECG-gated [11C]acetate PET for measuring left ventricular volumes, mass, and myocardial external efficiency

scientific article published on 01 October 2016

Establishment of a European Network for Urine and Kidney Proteomics

Evaluation of ECG-gated [(11)C]acetate PET for measuring left ventricular volumes, mass, and myocardial external efficiency

scientific article

Expression of renal aquaporins is down-regulated in children with congenital hydronephrosis

scientific article published in January 2009

FDG-PET reproducibility in tumor-bearing mice: comparing a traditional SUV approach with a tumor-to-brain tissue ratio approach

scientific article published on 17 January 2017

Functional requirement of aquaporin-5 in plasma membranes of sweat glands.

scientific article

GFR prediction from cystatin C and creatinine in children: effect of including body cell mass.

scientific article published on 29 October 2011

Gender differences in nighttime plasma arginine vasopressin and delayed compensatory urine output in the elderly population after desmopressin

scientific article published on 22 October 2007

Glomerular and tubular function during AT1 receptor blockade in pigs with neonatal induced partial ureteropelvic obstruction

scientific article published on 28 November 2006

Glucagon-like peptide-1 (GLP-1): effect on kidney hemodynamics and renin-angiotensin-aldosterone system in healthy men.

scientific article published on 5 March 2013

Glucagon-like peptide-1: effect on pro-atrial natriuretic peptide in healthy males

scientific article published on 21 January 2014

Guidance document for structured reporting of diuresis renography.

scientific article published on January 2012

Impact of co-morbidity on the risk of first-time myocardial infarction, stroke, or death after single-photon emission computed tomography myocardial perfusion imaging

scientific article published on 6 June 2014

Improved cardiopulmonary exercise function after modified Nuss operation for pectus excavatum

scientific article published on 21 December 2011

In Vivo Imaging of Human 11C-Metformin in Peripheral Organs: Dosimetry, Biodistribution, and Kinetic Analyses.

scientific article published on 28 July 2016

Increased AQP2 targeting in primary cultured IMCD cells in response to angiotensin II through AT1 receptor

scientific article published on 8 August 2006

Increased apical targeting of renal ENaC subunits and decreased expression of 11betaHSD2 in HgCl2-induced nephrotic syndrome in rats

scientific article published on 27 September 2005

Increased apical targeting of renal epithelial sodium channel subunits and decreased expression of type 2 11beta-hydroxysteroid dehydrogenase in rats with CCl4-induced decompensated liver cirrhosis

scientific article

Increased cyclooxygenase-2 expression and prostaglandin E2 production in pressurized renal medullary interstitial cells

scientific article

Increased expression and apical targeting of renal ENaC subunits in puromycin aminonucleoside-induced nephrotic syndrome in rats

scientific journal article

Increased expression but not targeting of ENaC in adrenalectomized rats with PAN-induced nephrotic syndrome

scientific article published on 10 January 2006

Increased expression of ENaC subunits and increased apical targeting of AQP2 in the kidneys of spontaneously hypertensive rats.

scientific article published on 14 June 2005

Increased renal adrenomedullin expression in rats with ureteral obstruction

scientific article published on 22 October 2008

Inter-observer agreement improves with PERCIST 1.0 as opposed to qualitative evaluation in non-small cell lung cancer patients evaluated with F-18-FDG PET/CT early in the course of chemo-radiotherapy

scientific article published on 22 September 2016

Key Roles of Renal Aquaporins in Water Balance and Water-Balance Disorders

scientific article published on 01 June 2000

Lithium-induced NDI in rats is associated with loss of alpha-ENaC regulation by aldosterone in CCD.

scientific article

Long-term aldosterone treatment induces decreased apical but increased basolateral expression of AQP2 in CCD of rat kidney

scientific journal article

Long-term vasopressin-V2-receptor stimulation induces regulation of aquaporin 4 protein in renal inner medulla and cortex of Brattleboro rats ⬇️

scientific article published on April 24, 2013

Maintained ENaC trafficking in aldosterone-infused rats during mineralocorticoid and glucocorticoid receptor blockade

scientific article published on 15 August 2006

Measurement of glomerular filtration rate with magnetic resonance imaging: principles, limitations, and expectations.

scientific article published on January 2008

Melamine-Related Urinary Stones in 195 Infants and Young Children: Clinical Features within 2 Years of Follow-Up ⬇️

scientific article published on 01 November 2011

Mice with targeted disruption of the acyl-CoA binding protein display attenuated urine concentrating ability and diminished renal aquaporin-3 abundance

scientific article published on 11 January 2012

Molecular imaging of cholinergic processes in prostate cancer using ¹¹C-donepezil and ¹⁸F-FEOBV.

scientific article published in August 2015

Molecular physiology of renal aquaporins and sodium transporters: exciting approaches to understand regulation of renal water handling

scientific article published on 07 September 2005

Monitoring Kidney Function in Neuroendocrine Tumor Patients Treated with (90)Y-DOTATOC: Associations with Risk Factors

scientific article published on 01 January 2015

Myocardial Oxygen Consumption and Efficiency in Aortic Valve Stenosis Patients With and Without Heart Failure.

scientific article published on 6 February 2017

Neonatal ureteral obstruction alters expression of renal sodium transporters and aquaporin water channels

scientific article published in July 2004

Neuronal precursor cell proliferation in the hippocampus after transient cerebral ischemia: a comparative study of two rat strains using stereological tools

scientific article

Noninvasive Detection of Cardiac Allograft Vasculopathy by Stress Exercise Echocardiographic Assessment of Myocardial Deformation

scientific article published on 18 February 2016

Normal differential renal function does not indicate a normal kidney after partial ureteropelvic obstruction and subsequent relief in 2-week-old piglets

scientific article

Normalized Cardiopulmonary Exercise Function in Patients With Pectus Excavatum Three Years After Operation

scientific article published on 14 May 2013

Oxygen tension correlates with regional blood flow in obstructed rat kidney

scientific article

Parecoxib is neuroprotective in spontaneously hypertensive rats after transient middle cerebral artery occlusion: a divided treatment response?

scientific article (publication date: 6 December 2006)

Pathogenesis of oedema in nephrotic syndrome: role of epithelial sodium channel

scientific article published on December 2007

Pre-existing renal failure worsens the outcome after intestinal ischaemia and reperfusion in rats

scientific article published on 04 June 2010

Precision and within- and between-day variation of bioimpedance parameters in children aged 2-14 years.

scientific article published on 11 November 2010

Proteomic identification of early changes in the renal cytoskeleton in obstructive uropathy

scientific article published on 23 April 2014

Puberty alters renal water handling.

scientific article

ROS dependence of cyclooxygenase-2 induction in rats subjected to unilateral ureteral obstruction.

scientific article published on 13 November 2013

Rapid and segmental specific dysregulation of AQP2, S256-pAQP2 and renal sodium transporters in rats with LPS-induced endotoxaemia

scientific article published on 4 February 2009

Recommendations for biomarker identification and qualification in clinical proteomics

scientific article published in August 2010

Reduced expression of Na-K-2Cl cotransporter in medullary TAL in vitamin D-induced hypercalcemia in rats

scientific article published on 01 January 2002

Reduced expression of renal Na+ transporters in rats with PTH-induced hypercalcemia.

scientific article published on 18 November 2003

Reduced number of glomeruli in kidneys with neonatally induced partial ureteropelvic obstruction in pigs

scientific article published on 01 March 2002

Reduced renal expression of AQP2, p-AQP2 and AQP3 in haemorrhagic shock-induced acute renal failure.

scientific article published in December 2003

Regulated expression of pendrin in rat kidney in response to chronic NH4Cl or NaHCO3 loading.

scientific article published on 22 October 2002

Regulation of AQP4 protein expression in rat brain astrocytes: role of P2X7 receptor activation

scientific article

Regulation of aquaporins and sodium transporter proteins in the solitary kidney in response to partial ureteral obstruction in neonatal rats

scientific article

Regulation of sodium transporters in the thick ascending limb of rat kidney: response to angiotensin II

scientific article published on 25 March 2003

Renal PET-imaging with (11)C-metformin in a transgenic mouse model for chronic kidney disease.

scientific article published on 23 June 2016

Renal aquaporins and sodium transporters with special focus on urinary tract obstruction

scientific article

Renal compensation to chronic hypoxic hypercapnia: downregulation of pendrin and adaptation of the proximal tubule

scientific article published on 19 December 2006

Renoprotective Effects of Metformin are Independent of Organic Cation Transporters 1 &2 and AMP-activated Protein Kinase in the Kidney

scientific article published on 26 October 2016

Reproducibility and repeatability of differential renal function in 4-week-old piglets

scientific article published in January 2008

Reproducibility of contrast enhanced magnetic resonance renography in adolescents

scientific article

Resistive index: an experimental study of acute complete unilateral ureteral obstruction

scientific article published in March 2003

Segment-specific ENaC downregulation in kidney of rats with lithium-induced NDI.

scientific article

Severe urinary concentrating defect in renal collecting duct-selective AQP2 conditional-knockout mice

scholarly article

Sleep deprivation induces excess diuresis and natriuresis in healthy children.

scientific article published on 19 October 2011

Structural and functional MRI in children with renal disease: first experience

scientific article published on 10 March 2010

Tankyrase-mediated β-catenin activity regulates vasopressin-induced AQP2 expression in kidney collecting duct mpkCCDc14 cells

scientific article published on 17 December 2014

Telmisartan attenuates chronic ciclosporin A nephrotoxicity in a pig model

scientific article published on 14 November 2006

The role of capillary transit time heterogeneity in myocardial oxygenation and ischemic heart disease

scientific article

The role of renal resistive index measures in the diagnostic work up of congenital hydronephrosis

scientific article published on 31 March 2006

The α-MSH analogue AP214 attenuates rise in pulmonary pressure and fall in ejection fraction in lipopolysaccharide-induced systemic inflammatory response syndrome in pigs

scientific article published on 4 October 2010

Tissue, urine and blood metabolite signatures of chronic kidney disease in the 5/6 nephrectomy rat model

scientific article published on 17 August 2019

Treatment with a human recombinant monoclonal IgG antibody against oxidized LDL in atherosclerosis-prone pigs reduces cathepsin S in coronary lesions

scientific article published on 2 April 2016

Treatment with the vascular disrupting agent combretastatin is associated with impaired AQP2 trafficking and increased urine output

scientific article

Unilateral ureteral obstruction alters expression of acid-base transporters in rat kidney

scientific article published on 28 October 2009

Unilateral ureteral obstruction induces DNA repair by APE1.

scientific article published on 25 November 2015

Ureter obstruction alters expression of renal acid-base transport proteins in rat kidney

scientific article published on 28 May 2008

Urinary NGAL, cystatin C, β2-microglobulin, and osteopontin significance in hydronephrotic children

scientific article published on 19 June 2012

Urinary biomarkers in prenatally diagnosed unilateral hydronephrosis

scientific article published on 08 January 2011

Urinary proteome analysis in congenital bilateral hydronephrosis

scientific article

Urinary tract obstruction induces transient accumulation of COX-2-derived prostanoids in kidney tissue

scientific article

Urine and kidney cytokine profiles in experimental unilateral acute and chronic hydronephrosis

scientific article published on 12 December 2011

Use of plasma clearance of technetium Tc 99m pentetate to estimate renal clearance during postnatal development in pigs

scientific article published on 01 August 2002

[11C]-Labeled Metformin Distribution in the Liver and Small Intestine Using Dynamic Positron Emission Tomography in Mice Demonstrates Tissue-Specific Transporter Dependency.

scientific article published on 18 March 2016

[Aprotinin scintigraphy in amyloidosis]

scientific article published on 01 May 2009

[Prenatal diagnosed hydronephrosis and other urological anomalies]

scientific article published on 26 June 2006

alpha-Lipoic acid prevents cisplatin-induced acute kidney injury in rats

scientific article published on 17 April 2009

alpha-MSH prevents impairment in renal function and dysregulation of AQPs and Na-K-ATPase in rats with bilateral ureteral obstruction

scientific article published on 27 September 2005

α-Melanocyte stimulating hormone treatment in pigs does not improve early graft function in kidney transplants from brain dead donors

scientific article

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