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List of works by Simone Hornemann

A bispecific immunotweezer prevents soluble PrP oligomers and abolishes prion toxicity

article

A molecular switch controls interspecies prion disease transmission in mice

scientific article

A scrapie-like unfolding intermediate of the prion protein domain PrP(121–231) induced by acidic pH ⬇️

scientific article published on May 26, 1998

Absolute Quantification of Amyloid Propagons by Digital Microfluidics

scientific article published on 3 October 2017

Autoantibodies against the prion protein in individuals with PRNP mutations

scientific article published on 25 February 2020

Binding of Polythiophenes to Amyloids: Structural Mapping of the Pharmacophore.

scientific article published on 27 November 2017

Cellular prion protein conformation and function

scientific article

De novo generation of a transmissible spongiform encephalopathy by mouse transgenesis

scientific article

Differential Toxicity of Antibodies to the Prion Protein

scientific article published on 28 January 2016

Enhanced detection of prion infectivity from blood by preanalytical enrichment with peptoid-conjugated beads

scientific article published on 12 September 2019

Functional Characterization of Germline Mutations in PDGFB and PDGFRB in Primary Familial Brain Calcification

scientific article

Genome-wide transcriptomics identifies an early preclinical signature of prion infection

scientific article published on 29 June 2020

Hydrogen/deuterium exchange mass spectrometry identifies two highly protected regions in recombinant full-length prion protein amyloid fibrils

scientific article

LAG3 is not expressed in human and murine neurons and does not modulate α-synucleinopathies

scientific article published on 26 July 2021

Modifiers of prion protein biogenesis and recycling identified by a highly parallel endocytosis kinetics assay

scientific article published on 24 March 2017

Multiple substitutions of methionine 129 in human prion protein reveal its importance in the amyloid fibrillation pathway

scientific article published on 5 June 2012

NMR characterization of the full‐length recombinant murine prion protein, mPrP(23–231) ⬇️

scientific article published on August 18, 1997

NMR structure of the bank vole prion protein at 20 degrees C contains a structured loop of residues 165-171

scientific article

NMR structure of the bovine prion protein isolated from healthy calf brains

scientific article

Neurotoxic Antibodies against the Prion Protein Do Not Trigger Prion Replication

scientific article

Polythiophenes inhibit prion propagation by stabilizing prion protein (PrP) aggregates

scientific article

Prion (PrPSc)-specific epitope defined by a monoclonal antibody ⬇️

scientific article published on November 6, 1997

Prion protein NMR structure from tammar wallaby (Macropus eugenii) shows that the beta2-alpha2 loop is modulated by long-range sequence effects

scientific article

Prion protein library of recombinant constructs for structural biology

scientific article

Prion protein mPrP[F175A](121-231): structure and stability in solution

scientific article

Prion protein structural features indicate possible relations to signal peptidases ⬇️

scientific article published on April 24, 1998

Prion protein-detergent micelle interactions studied by NMR in solution

scientific article published on 22 June 2009

Prion strain discrimination using luminescent conjugated polymers

Prion transmission prevented by modifying the β2-α2 loop structure of host PrPC

scientific article published on January 2014

Protease resistance of infectious prions is suppressed by removal of a single atom in the cellular prion protein

scientific article

Protective anti-prion antibodies in human immunoglobulin repertoires

scientific article published on 10 August 2020

Putative prion protein from Fugu (Takifugu rubripes).

scientific article published on 6 December 2007

Replication of modified vaccinia virus Ankara in primary chicken embryo fibroblasts requires expression of the interferon resistance gene E3L.

scientific article published in August 2003

Spongiform encephalopathy in transgenic mice expressing a point mutation in the β2-α2 loop of the prion protein

scientific article

Strain fidelity of chronic wasting disease upon murine adaptation ⬇️

scientific article

Structural plasticity of the cellular prion protein and implications in health and disease

scientific article published on 6 May 2013

Structure-based drug design identifies polythiophenes as antiprion compounds

scientific article

Superresolution imaging of amyloid fibrils with binding-activated probes

scientific article published on 22 April 2013

The POM monoclonals: a comprehensive set of antibodies to non-overlapping prion protein epitopes

scientific article

The adaptor ASC has extracellular and 'prionoid' activities that propagate inflammation

scientific article (publication date: August 2014)

The amyloid-Congo red interface at atomic resolution

scientific article

The prion protein is an agonistic ligand of the G protein-coupled receptor Adgrg6

scientific journal article

The toxicity of antiprion antibodies is mediated by the flexible tail of the prion protein

scientific article

Unaltered prion disease in mice lacking developmental endothelial locus-1

scientific article published on 11 January 2019

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