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List of works by Ang Guo

Ablation of the GNB3 gene in mice does not affect body weight, metabolism or blood pressure, but causes bradycardia.

scientific article

AutoTT: automated detection and analysis of T-tubule architecture in cardiomyocytes

scientific article

Ca2+ removal mechanisms in mouse embryonic stem cell-derived cardiomyocytes.

scientific article

Calsequestrin Accumulation in Rough Endoplasmic Reticulum Promotes Perinuclear Ca2+ Release ⬇️

scientific article published on March 28, 2012

Carvedilol and its new analogs suppress arrhythmogenic store overload-induced Ca2+ release

scientific article published on 10 July 2011

Cholesterol is required for maintaining T-tubule integrity and intercellular connections at intercalated discs in cardiomyocytes

scientific article published on 30 May 2016

E-C coupling structural protein junctophilin-2 encodes a stress-adaptive transcription regulator

scientific article published in Science

In situ single photon confocal imaging of cardiomyocyte T-tubule system from Langendorff-perfused hearts

scientific article published on 6 May 2015

MG53 is dispensable for T-tubule maturation but critical for maintaining T-tubule integrity following cardiac stress.

scientific article

MicroRNA: a toolkit fine-tuning the dyadic "fuzzy space"?

scientific article published on September 2012

Microtubule-mediated defects in junctophilin-2 trafficking contribute to myocyte transverse-tubule remodeling and Ca2+ handling dysfunction in heart failure.

scientific article published on 11 February 2014

Molecular Determinants of Calpain-dependent Cleavage of Junctophilin-2 Protein in Cardiomyocytes

scientific article published on 10 June 2015

Novel insights on the relationship between T-tubular defects and contractile dysfunction in a mouse model of hypertrophic cardiomyopathy.

scientific article published on 20 December 2015

Overexpression of junctophilin-2 does not enhance baseline function but attenuates heart failure development after cardiac stress.

scientific article

Phospholamban knockout breaks arrhythmogenic Ca²⁺ waves and suppresses catecholaminergic polymorphic ventricular tachycardia in mice

scientific article published on 15 July 2013

Preservation of the pHi during ischemia via PKC by intermittent hypoxia

scientific article published in 2007

Regional distribution of T-tubule density in left and right atria in dogs

scientific article published on 23 September 2016

Sildenafil ameliorates left ventricular T-tubule remodeling in a pressure overload-induced murine heart failure model

scientific article

Sildenafil prevents and reverses transverse-tubule remodeling and Ca(2+) handling dysfunction in right ventricle failure induced by pulmonary artery hypertension.

scientific article published on 27 December 2011

T-tubule remodeling during transition from hypertrophy to heart failure.

scientific article published on 24 June 2010

The cardiac ryanodine receptor luminal Ca2+ sensor governs Ca2+ waves, ventricular tachyarrhythmias and cardiac hypertrophy in calsequestrin-null mice.

scientific article

The ryanodine receptor store-sensing gate controls Ca2+ waves and Ca2+-triggered arrhythmias

scientific article

Transient activation of PKC results in long-lasting detrimental effects on systolic [Ca2+]i in cardiomyocytes by altering actin cytoskeletal dynamics and T-tubule integrity

scientific article published on 4 January 2018

β-Adrenergic receptor antagonists ameliorate myocyte T-tubule remodeling following myocardial infarction.

scientific article

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