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List of works by Jörn Dengjel

A Multi-layered Quantitative In Vivo Expression Atlas of the Podocyte Unravels Kidney Disease Candidate Genes.

scientific article

AMBRA1 interplay with cullin E3 ubiquitin ligases regulates autophagy dynamics

scientific article published on 11 December 2014

AMBRA1 links autophagy to cell proliferation and tumorigenesis by promoting c-Myc dephosphorylation and degradation

scientific article published on December 2014

ARP3 Controls the Podocyte Architecture at the Kidney Filtration Barrier

scientific article published on 29 November 2018

Accumulation of Basic Amino Acids at Mitochondria Dictates the Cytotoxicity of Aberrant Ubiquitin

scientific article published on 3 March 2015

Acetyl-coenzyme A: a metabolic master regulator of autophagy and longevity.

scientific article published on 15 May 2014

Anks3 alters the sub-cellular localization of the Nek7 kinase

scientific article published on 15 July 2015

Anks3 interacts with nephronophthisis proteins and is required for normal renal development

scientific journal article

Annexin A7 is required for ESCRT III-mediated plasma membrane repair

scientific article published on 30 April 2019

Autophagosomal protein dynamics and influenza virus infection.

scientific article published on 14 March 2012

Autophagosomal proteome analysis by protein correlation profiling-SILAC

scientific article published on 01 January 2014

Autophagy in innate and adaptive immunity against intracellular pathogens.

scientific article

Autophagy proteins stabilize pathogen-containing phagosomes for prolonged MHC II antigen processing.

scientific article

Axitinib and sorafenib are potent in tyrosine kinase inhibitor resistant chronic myeloid leukemia cells

scientific article published on 24 February 2016

Bacterial lectin BambL acts as a B cell superantigen

scientific article published on 03 November 2021

Beyond Global Charge: Role of Amine Bulkiness and Protein Fingerprint on Nanoparticle-Cell Interaction

scientific article published on 10 September 2018

Cardioprotection and lifespan extension by the natural polyamine spermidine.

scientific article

Cargo-selective SNX-BAR proteins mediate retromer trimer independent retrograde transport.

scientific article

Census of cytosolic aminopeptidase activity reveals two novel cytosolic aminopeptidases.

scientific article published on 14 September 2012

Characterization of early autophagy signaling by quantitative phosphoproteomics

scientific article published on 21 November 2013

Cilia-localized LKB1 regulates chemokine signaling, macrophage recruitment, and tissue homeostasis in the kidney

scientific article published on 19 June 2018

Combinatorial omics analysis reveals perturbed lysosomal homeostasis in collagen VII-deficient keratinocytes.

scientific article published on 11 January 2018

Combinatorial use of electrostatic repulsion-hydrophilic interaction chromatography (ERLIC) and strong cation exchange (SCX) chromatography for in-depth phosphoproteome analysis

scientific article published on 20 July 2012

Comparative quantitation of proteome alterations induced by aging or immortalization in primary human fibroblasts and keratinocytes for clinical applications

scientific article published on 10 May 2010

Comparison of ERLIC-TiO2, HILIC-TiO2, and SCX-TiO2 for global phosphoproteomics approaches

scientific article published on 08 July 2011

Consistency of the proteome in primary human keratinocytes with respect to gender, age, and skin localization

scientific article published on 30 May 2013

Control of RAB7 activity and localization through the retromer-TBC1D5 complex enables RAB7-dependent mitophagy

scientific article published on 20 November 2017

Cyclin O (Ccno) functions during deuterosome-mediated centriole amplification of multiciliated cells

scientific article published on 23 February 2015

Cyclin-dependent kinase 5 (CDK5) regulates the circadian clock

scientific article published on 05 November 2019

Degradation of protein translation machinery by amino acid starvation-induced macroautophagy.

scientific article published on 28 April 2017

Detection of novel non-M2-related antimitochondrial antibodies in patients with anti-M2 negative primary biliary cirrhosis.

scientific article

Dietary spermidine for lowering high blood pressure.

scientific article published on 24 January 2017

Differential quantitative analysis of MHC ligands by mass spectrometry using stable isotope labeling.

scientific article published on 7 March 2004

Discrete cytosolic macromolecular BRAF complexes exhibit distinct activities and composition

scientific article published on 16 January 2017

EEF1A1 deacetylation enables transcriptional activation of remyelination

scientific article published on 09 July 2020

Effects of the Extracellular Matrix on the Proteome of Primary Skin Fibroblasts

scientific article published on 01 January 2019

ErbB2-associated changes in the lysosomal proteome.

scientific article published on 14 June 2011

Erratum: Corrigendum: AMBRA1 links autophagy to cell proliferation and tumorigenesis by promoting c-Myc dephosphorylation and degradation

scholarly article published in Nature Cell Biology

Erratum: Sorafenib promotes graft-versus-leukemia activity in mice and humans through IL-15 production in FLT3-ITD-mutant leukemia cells

scientific article published on 01 April 2018

Expression of a ULK1/2 binding-deficient ATG13 variant can partially restore autophagic activity in ATG13-deficient cells

scientific article published on 25 July 2015

Fast and easy phosphopeptide fractionation by combinatorial ERLIC-SCX solid-phase extraction for in-depth phosphoproteome analysis

scientific article published on 3 December 2015

Feedback Inhibition of the Rag GTPase GAP Complex Lst4-Lst7 Safeguards TORC1 from Hyperactivation by Amino Acid Signals.

scientific article published in July 2017

Functional Proteomics Identifies Acinus L as a Direct Insulin- and Amino Acid-Dependent Mammalian Target of Rapamycin Complex 1 (mTORC1) Substrate.

scientific article published on 23 April 2015

Global kinome profiling reveals DYRK1A as critical activator of the human mitochondrial import machinery

scientific article published on 13 July 2021

Global proteome analyses of SILAC-labeled skin cells.

scientific article published on January 2013

Global remodelling of cellular microenvironment due to loss of collagen VII.

scientific article published on 16 April 2013

Glycan side chains on naturally presented MHC class II ligands.

scientific article

Guidelines and recommendations on yeast cell death nomenclature.

scientific article published in January 2018

Guidelines for the use and interpretation of assays for monitoring autophagy

scientific article

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

scientific article

HUWE1 E3 ligase promotes PINK1/PARKIN-independent mitophagy by regulating AMBRA1 activation via IKKα

scientific article published in Nature Communications

Hexokinase 3 enhances myeloid cell survival via non-glycolytic functions

scientific article published on 11 May 2022

Hydrophobic Interaction Chromatography for Bottom-Up Proteomics Analysis of Single Proteins and Protein Complexes

scientific article

Identification and Regulation of Multimeric Protein Complexes in Autophagy via SILAC-Based Mass Spectrometry Approaches

scientific article published on 01 January 2019

Identification of a naturally processed cyclin D1 T-helper epitope by a novel combination of HLA class II targeting and differential mass spectrometry

scientific article published on 01 December 2004

Identification of autophagosome-associated proteins and regulators by quantitative proteomic analysis and genetic screens.

scientific article

Identification of α-tubulin as an autoantigen recognized by sera from patients with neuropsychiatric systemic lupus erythematosus.

scientific article

Impaired lymphoid extracellular matrix impedes antibacterial immunity in epidermolysis bullosa

scientific article

Influenza A Virus Induces Autophagosomal Targeting of Ribosomal Proteins

scientific article published on 06 July 2018

Inhibition of β-catenin signaling by phenobarbital in hepatoma cells in vitro

scientific article published on 29 September 2016

Insights into autosomal dominant polycystic kidney disease by quantitative mass spectrometry-based proteomics.

scientific article

Involvement of mitochondrial dynamics in the segregation of mitochondrial matrix proteins during stationary phase mitophagy

scientific article published on January 2013

Lessons to be learned from primary renal cell carcinomas: novel tumor antigens and HLA ligands for immunotherapy

scientific article published on 31 December 2004

Losartan ameliorates dystrophic epidermolysis bullosa and uncovers new disease mechanisms

scientific article

Loss of collagen VII is associated with reduced transglutaminase 2 abundance and activity

scientific article published on 14 April 2014

Lsd1 Ablation Triggers Metabolic Reprogramming of Brown Adipose Tissue

scientific article

Macroautophagy Proteins Assist Epstein Barr Virus Production and Get Incorporated Into the Virus Particles.

scientific article published on 8 November 2014

Macroautophagy Proteins Control MHC Class I Levels on Dendritic Cells and Shape Anti-viral CD8(+) T Cell Responses.

scientific article published on 20 April 2016

Mapping Protein–Protein Interactions by Quantitative Proteomics ⬇️

scientific article published on January 1, 2010

Matrix protein 2 of influenza A virus blocks autophagosome fusion with lysosomes.

scientific article

Metadherin exon 11 skipping variant enhances metastatic spread of ovarian cancer.

scientific article

Methods to Study the BECN1 Interactome in the Course of Autophagic Responses.

scientific article published on 15 December 2016

Mitophagy as a stress response in mammalian cells and in respiring S. cerevisiae.

scientific article published on April 2016

Modeling non-hereditary mechanisms of Alzheimer disease during apoptosis in yeast

scientific article published on 20 March 2015

Molecular fingerprinting of the podocyte reveals novel gene and protein regulatory networks

article

Musical chairs during mitophagy

scientific article

Nrf2-Mediated Fibroblast Reprogramming Drives Cellular Senescence by Targeting the Matrisome

scientific article published on 01 July 2018

Ordered bulk degradation via autophagy.

scientific article published on 20 November 2008

Organelle proteomics by label-free and SILAC-based protein correlation profiling.

scientific article

Peptide motif for the rat MHC class II molecule RT1.Da: similarities to the multiple sclerosis-associated HLA-DRB1*1501 molecule.

scientific article published on 12 February 2005

Phospho-proteomic analyses of B-Raf protein complexes reveal new regulatory principles.

scientific article published on 28 March 2016

Phosphoproteomic profiling reveals a defined genetic program for osteoblastic lineage commitment of human bone marrow-derived stromal stem cells

scientific article published on 12 December 2019

Phosphorylation site dynamics of early T-cell receptor signaling

scientific article

Post-transcriptional regulation of ATG1 is a critical node that modulates autophagy during distinct nutrient stresses

scientific article published in 2021

Pro-inflammatory immunity supports fibrosis advancement in epidermolysis bullosa: intervention with Ang-(1-7)

scientific article published on 30 August 2021

Proteasomal degradation induced by DPP9-mediated processing competes with mitochondrial protein import

scientific article published on 20 August 2020

Protein and Molecular Characterization of a Clinically Compliant Amniotic Fluid Stem Cell-Derived Extracellular Vesicle Fraction Capable of Accelerating Muscle Regeneration Through Enhancement of Angiogenesis.

scientific article published on 5 July 2017

Protein complexes and neighborhoods driving autophagy

scientific article published on 13 November 2020

Protein import and oxidative folding in the mitochondrial intermembrane space of intact mammalian cells.

scientific article published on 15 May 2013

Proteomic profiling of fibroblasts isolated from chronic wounds identifies disease-relevant signaling pathways

scientific article published on 16 April 2020

Quantitative Proteomics Analysis of Leukemia Cells.

scientific article published on January 2016

Quantitative proteomic assessment of very early cellular signaling events

Quantitative proteomics for the analysis of spatio-temporal protein dynamics during autophagy.

scientific article

RACK1 Is an Interaction Partner of ATG5 and a Novel Regulator of Autophagy.

scientific article published on 20 June 2016

ROCK1/2 signaling contributes to corticosteroid-refractory acute graft-versus-host disease

scientific article published in 2024

Raft-like lipid microdomains drive autophagy initiation via AMBRA1-ERLIN1 molecular association within MAMs

scientific article published on 09 October 2020

Rapid combinatorial ERLIC-SCX solid-phase extraction for in-depth phosphoproteome analysis

scientific article published on 4 November 2013

Receptor tyrosine kinase signaling: a view from quantitative proteomics

scientific article

Relevance of the inner mitochondrial membrane enzyme F1F0-ATPase as an autoantigen in autoimmune liver disorders

scientific article published on 08 September 2011

Retromer and TBC1D5 maintain late endosomal RAB7 domains to enable amino acid-induced mTORC1 signaling

scientific article published on 20 August 2019

Retromer- and WASH-dependent sorting of nutrient transporters requires a multivalent interaction network with ANKRD50.

scientific article published on December 2016

RhoA activation by CNFy restores cell-cell adhesion in kindlin-2-deficient keratinocytes.

scientific article published on 12 May 2014

Roles of mitophagy in cellular physiology and development

scientific article published on 3 August 2016

SPATA2 promotes CYLD activity and regulates TNF-induced NF-κB signaling and cell death.

scientific article published on 25 July 2016

Scaffold-free 3D cell culture of primary skin fibroblasts induces profound changes of the matrisome

scientific article published on 12 May 2021

Secretome of adipose-derived mesenchymal stem cells promotes skeletal muscle regeneration through synergistic action of extracellular vesicle cargo and soluble proteins

scientific article published on 05 April 2019

Signal transduction by growth factor receptors: signaling in an instant

scientific article published on 20 September 2007

Single Amino Acid Deletion in Kindlin-1 Results in Partial Protein Degradation Which Can Be Rescued by Chaperone Treatment

scientific article published on 28 January 2016

Sorafenib promotes graft-versus-leukemia activity in mice and humans through IL-15 production in FLT3-ITD-mutant leukemia cells.

scientific article published on 12 February 2018

Spatially Distinct Pools of TORC1 Balance Protein Homeostasis

scientific article published on 06 December 2018

Spermidine Suppresses Age-Associated Memory Impairment by Preventing Adverse Increase of Presynaptic Active Zone Size and Release

scientific article (publication date: 29 September 2016)

Strategy for identifying dendritic cell-processed CD4+ T cell epitopes from the HIV gag p24 protein.

scientific article

Study of ULK1 Catalytic Activity and Its Regulation

scientific article published on 18 November 2016

Suppression of coatomer mutants by a new protein family with COPI and COPII binding motifs in Saccharomyces cerevisiae.

scientific article

Systems Biology and Bioinformatics in Aging Research: A Workshop Report

Targeting GATA transcription factors - a novel strategy for anti-aging interventions?

scientific article published on 06 May 2019

The APMAP interactome reveals new modulators of APP processing and beta-amyloid production that are altered in Alzheimer's disease

scientific article published on 31 January 2019

The Atypical Kinase RIOK1 Promotes Tumor Growth and Invasive Behavior

scientific article published on 12 April 2017

The Ca(2+)-Dependent Release of the Mia40-Induced MICU1-MICU2 Dimer from MCU Regulates Mitochondrial Ca(2+) Uptake

scientific journal article

The Degradative Inventory of the Cell: Proteomic Insights ⬇️

scientific article published on 03 February 2012

The HSP40 chaperone Ydj1 drives amyloid beta 42 toxicity

scientific article published on 04 April 2022

The balance of Id3 and E47 determines neural stem/precursor cell differentiation into astrocytes

scientific article

The cup of youth

scientific article published on 10 June 2014

The deubiquitinase Usp27x stabilizes the BH3-only protein Bim and enhances apoptosis

scientific journal article

The flavonoid 4,4'-dimethoxychalcone promotes autophagy-dependent longevity across species

scientific article published on 19 February 2019

The pro-apoptotic BH3-only protein Bim interacts with components of the translocase of the outer mitochondrial membrane (TOM)

scientific article published on 15 April 2015

The quantitative nuclear matrix proteome as a biochemical snapshot of nuclear organization

scientific article

Three-Dimensional Cell Culture Conditions Affect the Proteome of Cancer-Associated Fibroblasts

scientific article published on 23 July 2018

Treatment of keratinocytes with 4-phenylbutyrate in epidermolysis bullosa: Lessons for therapies in keratin disorders

scientific article published on 09 May 2019

Tumor-derived CTF1 (cardiotrophin 1) is a critical mediator of stroma-assisted and autophagy-dependent breast cancer cell migration, invasion and metastasis

scientific article published in 2022

Unexpected abundance of HLA class II presented peptides in primary renal cell carcinomas.

scientific article published on July 2006

Vectorial Import via a Metastable Disulfide-Linked Complex Allows for a Quality Control Step and Import by the Mitochondrial Disulfide Relay

scientific article published on 01 January 2019

Vertebrate lonesome kinase modulates the hepatocyte secretome to prevent perivascular liver fibrosis and inflammation

scientific article published on 12 April 2022

mTOR inhibits autophagy by controlling ULK1 ubiquitylation, self-association and function through AMBRA1 and TRAF6.

scientific article published on 24 March 2013

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