List of works - Sofia R Gameiro

Androgen deprivation therapy sensitizes triple negative breast cancer cells to immune-mediated lysis through androgen receptor independent modulation of osteoprotegerin

scientific article published on 22 March 2016

Attacking malignant cells that survive therapy: Exploiting immunogenic modulation.

scientific article

Cancer vaccines targeting carcinoembryonic antigen: state-of-the-art and future promise.

scientific article published on June 2013

Chemotherapy-induced immunogenic modulation of tumor cells enhances killing by cytotoxic T lymphocytes and is distinct from immunogenic cell death.

scientific article published on 16 March 2013

Combination regimens of radiation therapy and therapeutic cancer vaccines: mechanisms and opportunities

scientific article

Combination therapy with local radiofrequency ablation and systemic vaccine enhances antitumor immunity and mediates local and distal tumor regression

scientific article

Cooperative Immune-Mediated Mechanisms of the HDAC Inhibitor Entinostat, an IL15 Superagonist, and a Cancer Vaccine Effectively Synergize as a Novel Cancer Therapy

scientific article published on 23 October 2019

Defining molecular signature of pro-immunogenic radiotherapy targets in human prostate cancer cells

scientific article

Defining the molecular signature of chemotherapy-mediated lung tumor phenotype modulation and increased susceptibility to T-cell killing.

scientific article published on 8 February 2012

Efficient Tumor Clearance and Diversified Immunity through Neoepitope Vaccines and Combinatorial Immunotherapy

scientific article published on 10 July 2019

Epigenetic priming of both tumor and NK cells augments antibody-dependent cellular cytotoxicity elicited by the anti-PD-L1 antibody avelumab against multiple carcinoma cell types

scholarly article by Kristin C Hicks et al published 2018 in OncoImmunology

Expanding the use of monoclonal antibody therapy of cancer by using ionising radiation to upregulate antibody targets.

scientific article published on 20 February 2014

Functional and mechanistic advantage of the use of a bifunctional anti-PD-L1/IL-15 superagonist

scientific article published on 01 April 2020

If we build it they will come: targeting the immune response to breast cancer

scientific article published on 29 October 2019

Improving clinical benefit for prostate cancer patients through the combination of androgen deprivation and immunotherapy.

scientific article published on 2 March 2015

Inhibitors of histone deacetylase 1 reverse the immune evasion phenotype to enhance T-cell mediated lysis of prostate and breast carcinoma cells.

scientific article published on 03 February 2016

M7824, a novel bifunctional anti-PD-L1/TGFβ Trap fusion protein, promotes anti-tumor efficacy as monotherapy and in combination with vaccine

scientific article published on 14 February 2018

Radiation-induced modulation of costimulatory and coinhibitory T-cell signaling molecules on human prostate carcinoma cells promotes productive antitumor immune interactions

scientific article

Radiation-induced survival responses promote immunogenic modulation to enhance immunotherapy in combinatorial regimens.

scientific article

Rationale for IL-15 superagonists in cancer immunotherapy

scientific article published on 11 March 2020

Remodeling the tumor microenvironment via blockade of LAIR-1 and TGF-β signaling enables PD-L1-mediated tumor eradication

scientific article published on 01 April 2022

Sublethal exposure to alpha radiation (223Ra dichloride) enhances various carcinomas' sensitivity to lysis by antigen-specific cytotoxic T lymphocytes through calreticulin-mediated immunogenic modulation.

scientific article

The multi-functionality of N-809, a novel fusion protein encompassing anti-PD-L1 and the IL-15 superagonist fusion complex

scientific article published on 27 November 2018

The tipping point for combination therapy: cancer vaccines with radiation, chemotherapy, or targeted small molecule inhibitors

scientific article

Two may be better than one: PD-1/PD-L1 blockade combination approaches in metastatic breast cancer

scientific article published on 08 October 2019

Vaccine-mediated immunotherapy directed against a transcription factor driving the metastatic process.

scientific article

List of works by Sofia R Gameiro

Androgen deprivation therapy sensitizes triple negative breast cancer cells to immune-mediated lysis through androgen receptor independent modulation of osteoprotegerin

Attacking malignant cells that survive therapy: Exploiting immunogenic modulation.

Cancer vaccines targeting carcinoembryonic antigen: state-of-the-art and future promise.

Chemotherapy-induced immunogenic modulation of tumor cells enhances killing by cytotoxic T lymphocytes and is distinct from immunogenic cell death.

Combination regimens of radiation therapy and therapeutic cancer vaccines: mechanisms and opportunities

Combination therapy with local radiofrequency ablation and systemic vaccine enhances antitumor immunity and mediates local and distal tumor regression

Cooperative Immune-Mediated Mechanisms of the HDAC Inhibitor Entinostat, an IL15 Superagonist, and a Cancer Vaccine Effectively Synergize as a Novel Cancer Therapy

Defining molecular signature of pro-immunogenic radiotherapy targets in human prostate cancer cells

Defining the molecular signature of chemotherapy-mediated lung tumor phenotype modulation and increased susceptibility to T-cell killing.

Efficient Tumor Clearance and Diversified Immunity through Neoepitope Vaccines and Combinatorial Immunotherapy

Epigenetic priming of both tumor and NK cells augments antibody-dependent cellular cytotoxicity elicited by the anti-PD-L1 antibody avelumab against multiple carcinoma cell types

Expanding the use of monoclonal antibody therapy of cancer by using ionising radiation to upregulate antibody targets.

Functional and mechanistic advantage of the use of a bifunctional anti-PD-L1/IL-15 superagonist

If we build it they will come: targeting the immune response to breast cancer

Improving clinical benefit for prostate cancer patients through the combination of androgen deprivation and immunotherapy.

Inhibitors of histone deacetylase 1 reverse the immune evasion phenotype to enhance T-cell mediated lysis of prostate and breast carcinoma cells.

M7824, a novel bifunctional anti-PD-L1/TGFβ Trap fusion protein, promotes anti-tumor efficacy as monotherapy and in combination with vaccine

Radiation-induced modulation of costimulatory and coinhibitory T-cell signaling molecules on human prostate carcinoma cells promotes productive antitumor immune interactions

Radiation-induced survival responses promote immunogenic modulation to enhance immunotherapy in combinatorial regimens.

Rationale for IL-15 superagonists in cancer immunotherapy

Remodeling the tumor microenvironment via blockade of LAIR-1 and TGF-β signaling enables PD-L1-mediated tumor eradication

Sublethal exposure to alpha radiation (223Ra dichloride) enhances various carcinomas' sensitivity to lysis by antigen-specific cytotoxic T lymphocytes through calreticulin-mediated immunogenic modulation.

The multi-functionality of N-809, a novel fusion protein encompassing anti-PD-L1 and the IL-15 superagonist fusion complex

The tipping point for combination therapy: cancer vaccines with radiation, chemotherapy, or targeted small molecule inhibitors

Two may be better than one: PD-1/PD-L1 blockade combination approaches in metastatic breast cancer

Vaccine-mediated immunotherapy directed against a transcription factor driving the metastatic process.