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List of works by James B McAlpine

2D NMR barcoding and differential analysis of complex mixtures for chemical identification: the Actaea triterpenes

scientific article published on 27 March 2014

A dynamic mechanical method to assess bulk viscoelastic behavior of the dentin extracellular matrix

scientific article published on 28 October 2020

A galloylated dimeric proanthocyanidin from grape seed exhibits dentin biomodification potential

scientific article

Absolute Configuration of Native Oligomeric Proanthocyanidins with Dentin Biomodification Potency

scientific article published on 18 January 2017

Analysis and purification of bioactive natural products: the AnaPurNa study.

scientific article

Antimycobacterial Rufomycin Analogues from Streptomyces atratus Strain MJM3502 ⬇️

scientific article published on 07 February 2020

Bioautography with TLC-MS/NMR for Rapid Discovery of Anti-tuberculosis Lead Compounds from Natural Sources.

scientific article published on 23 February 2016

Biosynthesis of diazepinomicin/ECO-4601, a Micromonospora secondary metabolite with a novel ring system.

scientific article published on 23 August 2008

Can Invalid Bioactives Undermine Natural Product-Based Drug Discovery?

scientific article

Centrifugal partition chromatography enables selective enrichment of trimeric and tetrameric proanthocyanidins for biomaterial development

scientific article published on 21 December 2017

Chemotaxonomic and biosynthetic relationships between flavonolignans produced by Silybum marianum populations.

scientific article

Chlorinated Coumarins from the Polypore MushroomFomitopsis officinalisand Their Activity againstMycobacterium tuberculosis ⬇️

scientific article (publication date: 25 October 2013)

Classification of Flavonoid Metabolomes via Data Mining and Quantification of Hydroxyl NMR Signals

scientific article published on 26 March 2020

Correction to Importance of Purity Evaluation and the Potential of Quantitative (1)H NMR as a Purity Assay

scientific article published on 17 November 2015

Correction: The value of universally available raw NMR data for transparency, reproducibility, and integrity in natural product research

scientific article published on 23 November 2018

Countercurrent Separation of Natural Products: An Update

scientific article

Countercurrent assisted quantitative recovery of metabolites from plant-associated natural deep eutectic solvents

scientific article

Cycloartane Triterpenes from the Aerial Parts of Actaea racemosa. ⬇️

scientific article published on 13 January 2016

Dentin biomodification: strategies, renewable resources and clinical applications

scientific article published on 03 December 2013

Dereplication, residual complexity, and rational naming: the case of the Actaea triterpenes

scientific article

Design of countercurrent separation of Ginkgo biloba terpene lactones by nuclear magnetic resonance

scientific article (publication date: 15 June 2012)

Digital NMR profiles as building blocks: assembling ¹H fingerprints of steviol glycosides

scientific article published on 25 February 2015

Discovery and characterization of the tuberculosis drug lead ecumicin ⬇️

scientific article published on 19 November 2014

Dissemination of original NMR data enhances reproducibility and integrity in chemical research

scientific article

Do Certain Flavonoid IMPS Have a Vital Function?

scientific article published on 02 December 2021

Essential parameters for structural analysis and dereplication by (1)H NMR spectroscopy.

scientific article

Evidence to the role of interflavan linkages and galloylation of proanthocyanidins at sustaining long-term dentin biomodification

scientific article published on 21 December 2018

Evolution of Quantitative Measures in NMR: Quantum Mechanical qHNMR Advances Chemical Standardization of a Red Clover (Trifolium pratense) Extract.

scientific article published on 09 January 2017

Galloyl moieties enhance the dentin biomodification potential of plant-derived catechins

scientific article published on 8 April 2014

Genomic analyses lead to novel secondary metabolites. Part 3. ECO-0501, a novel antibacterial of a new class. ⬇️

scientific article published in September 2006

HiFSA fingerprinting applied to isomers with near-identical NMR spectra: the silybin/isosilybin case

scientific article published on 5 March 2013

Holistic Analysis Enhances the Description of Metabolic Complexity in Dietary Natural Products

scientific article

Hytramycins V and I, anti-Mycobacterium tuberculosis hexapeptides from a Streptomyces hygroscopicus strain

scientific article published on 13 November 2013

Identification, characterization and potent antitumor activity of ECO-4601, a novel peripheral benzodiazepine receptor ligand

scientific article

Importance of purity evaluation and the potential of quantitative ¹H NMR as a purity assay.

scientific article

Isolation and identification of three new 5-alkenyl-3,3(2H)-furanones from two streptomyces species using a genomic screening approach. ⬇️

scientific article

K-targeted metabolomic analysis extends chemical subtraction to DESIGNER extracts: selective depletion of extracts of hops (Humulus lupulus).

scientific article published on December 2014

Linear regression analysis of silychristin A, silybin A and silybin B contents in Silybum marianum

scientific article published on 29 November 2018

Lipidated steroid saponins from Dioscorea villosa (wild yam).

scientific article published on 19 August 2013

Metabolite Profiling and Classification of DNA-Authenticated Licorice Botanicals

scientific article

Microbial genomics as a guide to drug discovery and structural elucidation: ECO-02301, a novel antifungal agent, as an example.

scientific article published in April 2005

Mimicking the hierarchical functions of dentin collagen cross-links with plant derived phenols and phenolic acids

scientific article

Molecular basis for chloronium-mediated meroterpene cyclization: cloning, sequencing, and heterologous expression of the napyradiomycin biosynthetic gene cluster ⬇️

scientific article published on 28 March 2007

NMR reveals an undeclared constituent in custom synthetic peptides

scientific article published on 10 October 2019

Natural Deep Eutectic Solvents: Properties, Applications, and Perspectives.

scientific article published on 7 March 2018

Natural products, both small and large, and a focus on cancer treatment

scientific article published on 01 March 2009

Oligomeric proanthocyanidins released from dentin induce regenerative dental pulp cell response

scientific article published on 29 March 2017

Orthogonal analytical methods for botanical standardization: determination of green tea catechins by qNMR and LC-MS/MS.

scientific article published on 21 June 2013

Paradoxical effects of galloyl motifs in the interactions of proanthocyanidins with collagen‐rich dentin

scientific article published in 2021

Pharmacognosy of black cohosh: the phytochemical and biological profile of a major botanical dietary supplement.

scientific article

Post genomics - from antibody production to small molecule discovery

scientific article published on 01 March 2008

Preparation of DESIGNER extracts of red clover (Trifolium pratense L.) by centrifugal partition chromatography

scientific article published on 29 May 2019

Proanthocyanidin Dimers and Trimers from Vitis vinifera Provide Diverse Structural Motifs for the Evaluation of Dentin Biomodification

scientific article published on 21 August 2019

Proanthocyanidin Tetramers and Pentamers from Cinnamomum verum Bark and Their Dentin Biomodification Bioactivities

scientific article published in 2022

Proton fingerprints portray molecular structures: enhanced description of the 1H NMR spectra of small molecules

scientific article

Quality Control of Therapeutic Peptides by H NMR HiFSA Sequencing

scientific article published on 22 February 2019

Quantification of a botanical negative marker without an identical standard: ginkgotoxin in Ginkgo biloba.

scientific article published on 16 January 2014

Quantum Mechanics-Based Structure Analysis of Cyclic Monoterpene Glycosides from Rhodiola Rosea

scholarly article published 2 March 2020

Quantum Mechanics-Based Structure Analysis of Cyclic Monoterpene Glycosides from Rhodiola rosea

scientific article published on 28 May 2020

Quantum mechanical NMR full spin analysis in pharmaceutical identity testing and quality control

scientific article published on 08 September 2020

Rare A-Type, Spiro-Type, and Highly Oligomeric Proanthocyanidins from Pinus massoniana

scientific article published on 08 July 2020

Residual Complexity Does Impact Organic Chemistry and Drug Discovery: The Case of Rufomyazine and Rufomycin. ⬇️

scientific article published on 24 May 2018

Rufomycin Targets ClpC1 Proteolysis in Mycobacterium tuberculosis and M. abscessus

scholarly article by Mary P Choules et al published March 2019 in Antimicrobial Agents and Chemotherapy

Rufomycins or Ilamycins: Naming Clarifications and Definitive Structural Assignments

scientific article published in 2021

Selective Depletion and Enrichment of Constituents in "Curcumin" and Other Curcuma longa Preparations

scientific article published on 08 March 2019

Selective Preparation and High Dynamic-Range Analysis of Cannabinoids in “CBD Oil” and Other Cannabis sativa Preparations

scientific article published in 2022

Separation and Purification of Macrolides Using the Ito Multi-Layered Horizontal Coil Planet Centrifuge

scientific article published on 7 July 2007

Separation of natural products by countercurrent chromatography

scientific article published on 01 January 2012

Silica Gel-mediated Oxidation of Prenyl Motifs Generates Natural Product-Like Artifacts

scientific article published in 2021

Silybum marianum pericarp yields enhanced silymarin products.

scientific article

Solvent System Selection Strategies in Countercurrent Separation

scientific article

Strategies in anti-Mycobacterium tuberculosis drug discovery based on phenotypic screening

scientific article published on 11 July 2019

Structural Sequencing of Oligopeptides Aided by 1H Iterative Full-Spin Analysis.

scientific article published on 16 October 2017

Studying Mass Balance and the Stability of (Z)-Ligustilide from Angelica sinensis Helps to Bridge a Botanical Instability-Bioactivity Chasm

scientific article published on 03 September 2019

Subtle Chemical Shifts Explain the NMR Fingerprints of Oligomeric Proanthocyanidins with High Dentin Biomodification Potency

scientific article published on 27 July 2015

Sweet spot matching: A thin-layer chromatography-based countercurrent solvent system selection strategy

scientific article published on 27 April 2017

TLN-05220, TLN-05223, new Echinosporamicin-type antibiotics, and proposed revision of the structure of bravomicins(*). ⬇️

scientific article

Tandem of Countercurrent Separation and qHNMR Enables Gravimetric Analyses: Absolute Quantitation of the Rhodiola rosea Metabolome

scientific article published in 2021

Targeting Trimeric and Tetrameric Proanthocyanidins of Cinnamomum verum Bark as Bioactives for Dental Therapies

scientific article published on 05 November 2020

The 9th International Countercurrent Chromatography Conference held at Dominican University, Chicago, USA, August 1-3, 2016.

scientific article published on 19 September 2017

The Generally Useful Estimate of Solvent Systems (GUESS) method enables the rapid purification of methylpyridoxine regioisomers by countercurrent chromatography.

scientific article

The Untargeted Capability of NMR Helps Recognizing Nefarious Adulteration in Natural Products

scientific article published on 12 March 2021

The biosynthesis of coloradocin

scientific article published on 25 April 2003

The cyclic peptide ecumicin targeting ClpC1 is active against Mycobacterium tuberculosis in vivo

scientific article

The influence of natural deep eutectic solvents on bioactive natural products: studying interactions between a hydrogel model and Schisandra chinensis metabolites.

scientific article published on 21 February 2018

The value of universally available raw NMR data for transparency, reproducibility, and integrity in natural product research

article by James B. McAlpine et al published 13 July 2018 in Natural Product Reports

Toward Structural Correctness: Aquatolide and the Importance of 1D Proton NMR FID Archiving

scientific article

Tri- and Tetrameric Proanthocyanidins with Dentin Bioactivities from Pinus massoniana

scientific article published on 17 June 2020

Universal quantitative NMR analysis of complex natural samples

scientific article published on 14 September 2013

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