List of works by Rossella Manfredini

A functionally active RARalpha nuclear receptor is expressed in retinoic acid non responsive early myeloblastic cell lines.

scientific article published in January 2001

Abnormal expression patterns of WT1-as, MEG3 and ANRIL long non-coding RNAs in CD34+ cells from patients with primary myelofibrosis and their clinical correlations.

scientific article

Abundance of the primary transcript and its processed product of growth-related genes in normal and leukemic cells during proliferation and differentiation

scientific article published on 01 January 1992

All-trans-retinoic acid induces simultaneously granulocytic differentiation and expression of inflammatory cytokines in HL-60 cells

scientific article published on 01 February 1995

Antiapoptotic effect of c-fes protooncogene during granulocytic differentiation

scientific article published on 01 April 1994

Antisense inhibition of Bax mRNA increases survival of terminally differentiated HL60 cells

scientific article published on 01 August 1998

Antisense inhibition of c-fes proto-oncogene blocks PMA-induced macrophage differentiation in HL60 and in FDC-P1/MAC-11 cells

scientific article published on 01 January 1997

Antisense strategies to characterize the role of genes and oncogenes involved in myeloid differentiation

scientific article published on October 28, 1992

BTK Inhibitors Impair Platelet-Mediated Antifungal Activity

scientific article published in 2022

Bone marrow-derived hematopoietic cells undergo myogenic differentiation following a Pax-7 independent pathway.

scientific article published in May 2010

Bone marrow-specific loss of induces myeloproliferative neoplasm with features resembling human myelofibrosis

scientific article published on 13 September 2018

CALR mutational status identifies different disease subtypes of essential thrombocythemia showing distinct expression profiles

scientific article published on 8 December 2017

Calreticulin Ins5 and Del52 mutations impair unfolded protein and oxidative stress responses in K562 cells expressing CALR mutants

scientific article published on 22 July 2019

Calreticulin mutation-specific immunostaining in myeloproliferative neoplasms: pathogenetic insight and diagnostic value

scientific article published on 12 March 2014

Co-culture of hematopoietic stem/progenitor cells with human osteblasts favours mono/macrophage differentiation at the expense of the erythroid lineage.

scientific article

Correlation between differentiation plasticity and mRNA expression profiling of CD34+-derived CD14- and CD14+ human normal myeloid precursors

scientific article published on 10 June 2005

Deregulated expression of miR-29a-3p, miR-494-3p and miR-660-5p affects sensitivity to tyrosine kinase inhibitors in CML leukemic stem cells

scientific article published on 8 May 2017

Detection of low abundance mRNA of myeloid specific genes in cells of acute and chronic lymphoid leukemias by cRNA hybridization

scientific article published on 01 October 1990

Development of an IL-6 antagonist peptide that induces apoptosis in 7TD1 cells.

scientific article published on August 2003

Differential effects of c-myb and c-fes antisense oligodeoxynucleotides on granulocytic differentiation of human myeloid leukemia HL60 cells

scientific article published on 01 November 1990

Differential proteomic profile of leukemic CD34+ progenitor cells from chronic myeloid leukemia patients.

scientific article

Eosinophils, but not neutrophils, exhibit an efficient DNA repair machinery and high nucleolar activity.

scientific article published on October 2007

Expression and function of nerve growth factor and nerve growth factor receptor on cultured keratinocytes.

scientific article

Expression of B7 costimulatory molecule in cultured human epidermal Langerhans cells is regulated at the mRNA level

scientific article published on 01 July 1994

Expression of interleukins 1, 3, 6, stem cell factor and their receptors in acute leukemia blast cells and in normal peripheral lymphocytes and monocytes

scientific article published on 01 March 1993

Extracellular purines promote the differentiation of human bone marrow-derived mesenchymal stem cells to the osteogenic and adipogenic lineages

scientific article published on 21 December 2012

Genomic landscape of megakaryopoiesis and platelet function defects

scientific article

Hepatocyte growth factor favors monocyte differentiation into regulatory interleukin (IL)-10++IL-12low/neg accessory cells with dendritic-cell features

scientific article published on 09 March 2006

Impact of mutational status on outcomes in myelofibrosis patients treated with ruxolitinib in the COMFORT-II study

scientific article

Induction of a functional vitamin D receptor in all-trans-retinoic acid-induced monocytic differentiation of M2-type leukemic blast cells.

scientific article published on August 1999

Inhibition of c-fes expression by an antisense oligomer causes apoptosis of HL60 cells induced to granulocytic differentiation.

scientific article published on August 1993

Inhibition of cell growth by accumulated spermine is associated with a transient alteration of cell cycle progression

scientific article published on 01 January 1996

Involvement of MAF/SPP1 axis in the development of bone marrow fibrosis in PMF patients

scientific article

Isolation and characterization of a murine resident liver stem cell.

scientific article published on 12 October 2007

MYB controls erythroid versus megakaryocyte lineage fate decision through the miR-486-3p-mediated downregulation of MAF.

scientific article

MicroRNA expression profile in granulocytes from primary myelofibrosis patients.

scientific article

Molecular and functional analysis of the stem cell compartment of chronic myelogenous leukemia reveals the presence of a CD34- cell population with intrinsic resistance to imatinib

scientific article published in December 2009

Molecular profiling of CD34+ cells in idiopathic myelofibrosis identifies a set of disease-associated genes and reveals the clinical significance of Wilms' tumor gene 1 (WT1).

scientific article published on 21 September 2006

Mutated clones driving leukemic transformation are already detectable at the single-cell level in CD34-positive cells in the chronic phase of primary myelofibrosis

scientific article published on 04 February 2021

Novel Molecular Insights into Leukemic Evolution of Myeloproliferative Neoplasms: A Single Cell Perspective

scientific article published in 2022

Overexpression of c-kit in a leukemic cell population carrying a trisomy 4 and its relationship with the proliferative capacity

scientific article published on 01 April 1993

Physiological levels of 1alpha, 25 dihydroxyvitamin D3 induce the monocytic commitment of CD34+ hematopoietic progenitors.

scientific article published in April 2002

Presence of a functional vitamin D receptor does not correlate with vitamin D3 phenotypic effects in myeloid differentiation

scientific article published on 01 August 1997

Proliferation, differentiation arrest, and survival in leukemic blast cells.

scientific article published on November 1992

Purinergic signaling inhibits human acute myeloblastic leukemia cell proliferation, migration, and engraftment in immunodeficient mice.

scientific article

Purinergic stimulation of human mesenchymal stem cells potentiates their chemotactic response to CXCL12 and increases the homing capacity and production of proinflammatory cytokines

scientific article published on 09 December 2010

Requirement of the coiled-coil domains of p92(c-Fes) for nuclear localization in myeloid cells upon induction of differentiation.

scientific article published in March 2003

Role of TGF-β1/miR-382-5p/SOD2 axis in the induction of oxidative stress in CD34+ cells from primary myelofibrosis

scientific article published on 16 November 2018

Role of c-fes protooncogene in myeloid differentiation.

scientific article published on July 1995

Targeted cancer exome sequencing reveals recurrent mutations in myeloproliferative neoplasms

scientific article

Terminal differentiation

scientific article published on November 21, 1992

The extracellular nucleotide UTP is a potent inducer of hematopoietic stem cell migration

The number of prognostically detrimental mutations and prognosis in primary myelofibrosis: an international study of 797 patients

scientific article published on 19 February 2014

Transcriptional profiles in melanocytes from clinically unaffected skin distinguish the neoplastic growth pattern in patients with melanoma

scientific article published on 01 January 2007

Valproic acid triggers erythro/megakaryocyte lineage decision through induction of GFI1B and MLLT3 expression

scientific article published on 10 August 2012

Virally mediated MafB transduction induces the monocyte commitment of human CD34+ hematopoietic stem/progenitor cells

scientific article

[Expression of lactoferrin and myeloperoxidase genes in blasts of acute lymphoblastic leukemia]

scientific article published on 01 October 1989

[Mitochondrial DNA deletion in a case of progressive ophthalmoplegia]

scientific article published on 01 April 1990

[Possible correlations between proliferation and differentiation of blast cells in acute promyelocytic leukemia: a molecular study]

scientific article published on 01 October 1988

c-myb supports erythropoiesis through the transactivation of KLF1 and LMO2 expression.

scientific article published on 4 August 2010

miRNA-mRNA integrative analysis in primary myelofibrosis CD34+ cells: role of miR-155/JARID2 axis in abnormal megakaryopoiesis

scientific article

miRNA142-3p targets Tet2 and impairs Treg differentiation and stability in models of type 1 diabetes

scientific article published on 13 December 2019

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