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List of works by Jeremy M Sivak

1.15 A crystal structure of the X. tropicalis Spred1 EVH1 domain suggests a fourth distinct peptide-binding mechanism within the EVH1 family.

scientific article published in February 2005

All roads lead to glaucoma: Induced retinal injury cascades contribute to a common neurodegenerative outcome

scientific article published on 14 November 2018

An effective prodrug strategy to selectively enhance ocular exposure of a cannabinoid receptor (CB1/2) agonist.

scientific article published on 19 June 2013

An endogenous PI3K interactome promoting astrocyte mediated neuroprotection identifies a novel association with RNA binding protein ZC3H14

scientific article published on 24 November 2020

Angiogenic Dysfunction in Bone Marrow-Derived Early Outgrowth Cells from Diabetic Animals Is Attenuated by SIRT1 Activation ⬇️

scientific article published on November 26, 2012

Aqueous humor endothelin-1 and total retinal blood flow in patients with non-proliferative diabetic retinopathy.

scientific article

Aqueous humour concentrations of TGF-β, PLGF and FGF-1 and total retinal blood flow in patients with early non-proliferative diabetic retinopathy.

scientific article published on 28 September 2016

Astrocyte-derived lipoxins A4 and B4 promote neuroprotection from acute and chronic injury

scientific article published on 6 November 2017

Biomechanical insult switches PEA-15 activity to uncouple its anti-apoptotic function and promote erk mediated tissue remodeling

scientific article published on 23 November 2015

Curcuminoids inhibit the angiogenic response stimulated by fibroblast growth factor-2, including expression of matrix metalloproteinase gelatinase B

scientific article published on 01 April 2000

Dexmedetomidine Prevents Excessive γ-Aminobutyric Acid Type A Receptor Function after Anesthesia

scientific article published on 01 September 2018

Discovery of Oral VEGFR-2 Inhibitors with Prolonged Ocular Retention That Are Efficacious in Models of Wet Age-Related Macular Degeneration.

scientific article published on 15 November 2015

Effect of gamma-synuclein overexpression on matrix metalloproteinases in retinoblastoma Y79 cells.

scientific article

Fair-Weather Friends: Evidence of Lipoxin Dysregulation in Neurodegeneration

scientific article published on 07 January 2020

Lamina Cribrosa Pore Shape and Size as Predictors of Neural Tissue Mechanical Insult

scientific article published on October 2017

MMPs in the eye: emerging roles for matrix metalloproteinases in ocular physiology.

scientific article

Ocular inflammation in HLA-B27 transgenic mice reveals a potential role for MHC class I in corneal immune privilege

scientific article

PGC-1α signaling coordinates susceptibility to metabolic and oxidative injury in the inner retina

scientific article published on 05 February 2014

Pax-6 expression and activity are induced in the reepithelializing cornea and control activity of the transcriptional promoter for matrix metalloproteinase gelatinase B.

scientific article published on June 2000

Pharmacologic inhibition of reactive gliosis blocks TNF-α-mediated neuronal apoptosis

scientific article published on 29 September 2016

Pharmacologic uncoupling of angiogenesis and inflammation during initiation of pathological corneal neovascularization

scientific article published on 9 November 2011

Positive influence of AP-2alpha transcription factor on cadherin gene expression and differentiation of the ocular surface

scientific article published on April 2003

Preclinical development and ocular biodistribution of gemini-DNA nanoparticles after intravitreal and topical administration: towards non-invasive glaucoma gene therapy.

scientific article published on 4 June 2014

Proteomics analyses of human optic nerve head astrocytes following biomechanical strain.

scientific article published on 29 November 2011

ROS detoxification and proinflammatory cytokines are linked by p38 MAPK signaling in a model of mature astrocyte activation

scientific article (publication date: 2013)

Retinal blood oxygen saturation and aqueous humour biomarkers in early diabetic retinopathy

scientific article published on 28 January 2019

The AMPK-PGC-1α signaling axis regulates the astrocyte glutathione system to protect against oxidative and metabolic injury

scientific article published on 10 February 2018

The Discovery of N-(1-Methyl-5-(trifluoromethyl)-1H-pyrazol-3-yl)-5-((6- ((methylamino)methyl)pyrimidin-4-yl)oxy)-1H-indole-1-carboxamide (Acrizanib), a VEGFR-2 Inhibitor Specifically Designed for Topical Ocular Delivery, as a Therapy for Neovascula

scientific article

The aging eye: common degenerative mechanisms between the Alzheimer's brain and retinal disease.

scientific article published on 30 January 2013

Transcription Factors Pax6 and AP-2alpha Interact To Coordinate Corneal Epithelial Repair by Controlling Expression of Matrix Metalloproteinase Gelatinase B

scientific article

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