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List of works by Peter Heeringa

A plasmid-encoded peptide from Staphylococcus aureus induces anti-myeloperoxidase nephritogenic autoimmunity

scientific article published on 29 July 2019

ANCA and anti-GBM antibodies in diagnosis and follow-up of vasculitic disease.

scientific article

ANCA-small vessel vasculitides: what have we (not yet) learned from animal models?

scientific article published on June 2009

Accumulation of Myeloperoxidase-Positive Neutrophils in Atherosclerotic Lesions in LDLR −/− Mice

scientific article published on 08 November 2007

Age-dependent role of microvascular endothelial and polymorphonuclear cells in lipopolysaccharide-induced acute kidney injury.

scientific article

Age-determined severity of anti-myeloperoxidase autoantibody-mediated glomerulonephritis in mice

scientific article published on 01 February 2017

Alkylating histone deacetylase inhibitors may have therapeutic value in experimental myeloperoxidase-ANCA vasculitis

scientific article published on 26 August 2018

Altered B cell balance, but unaffected B cell capacity to limit monocyte activation in anti-neutrophil cytoplasmic antibody-associated vasculitis in remission

scientific article published on 10 April 2014

Alternative complement pathway in the pathogenesis of disease mediated by anti-neutrophil cytoplasmic autoantibodies

scientific article published on January 2007

Animal models of anti-neutrophil cytoplasmic antibody associated vasculitis.

scientific article published on February 1998

Anti-oxLDL antibody isotype levels, as potential markers for progressive atherosclerosis in APOE and APOECD40L mice

scientific article published on 05 September 2008

Autoantibodies to box A of high mobility group box 1 in systemic lupus erythematosus

scientific article published on 28 February 2017

Autoantibodies vex the vasculature

scientific article published on 01 October 2008

Bacterial DNA motifs trigger ANCA production in ANCA-associated vasculitis in remission

scientific article published on 11 December 2010

Bacterial infections in Wegener's granulomatosis: mechanisms potentially involved in autoimmune pathogenesis.

scientific article published on July 2011

Beneficial effects of alternate dietary regimen on liver inflammation, atherosclerosis and renal activation

scientific article (publication date: 31 March 2011)

Beneficial effects of an alternating high- fat dietary regimen on systemic insulin resistance, hepatic and renal inflammation and renal function

scientific article

Bone Marrow Transplantations to Study Gene Function in Hematopoietic Cells

article

Cellular immune regulation in the pathogenesis of ANCA-associated vasculitides

scientific article published on 8 February 2018

Checks and Balances in Autoimmune Vasculitis.

scientific article published on 22 February 2018

Chemokine receptor co-expression reveals aberrantly distributed TH effector memory cells in GPA patients

scientific article published on 14 June 2017

Coexpression of CD177 and membrane proteinase 3 on neutrophils in antineutrophil cytoplasmic autoantibody-associated systemic vasculitis: anti-proteinase 3-mediated neutrophil activation is independent of the role of CD177-expressing neutrophils.

scientific article published in May 2009

Complement activation is involved in renal damage in human antineutrophil cytoplasmic autoantibody associated pauci-immune vasculitis

scientific article published on 10 December 2008

Complement is crucial in the pathogenesis of ANCA-associated vasculitis.

scientific article published in January 2013

Decreased Expression of Negative Immune Checkpoint VISTA by CD4+ T Cells Facilitates T Helper 1, T Helper 17, and T Follicular Helper Lineage Differentiation in GCA

scientific article published on 16 July 2019

Dendritic cells overexpressing Fas-ligand induce pulmonary vasculitis in mice.

scientific article published on July 2004

Differential expression of granulopoiesis related genes in neutrophil subsets distinguished by membrane expression of CD177.

scientific article

Dual effect of chemokine CCL7/MCP-3 in the development of renal tubulointerstitial fibrosis.

scientific article

Effects of Anthocyanin and Flavanol Compounds on Lipid Metabolism and Adipose Tissue Associated Systemic Inflammation in Diet-Induced Obesity.

scientific article published on 6 June 2016

Effects of chocolate supplementation on metabolic and cardiovascular parameters in ApoE3L mice fed a high-cholesterol atherogenic diet.

scientific article published on 15 August 2013

Endothelial Interferon Regulatory Factor 1 Regulates Lipopolysaccharide-Induced VCAM-1 Expression Independent of NFκB.

scientific article published on 29 June 2017

Epicatechin attenuates atherosclerosis and exerts anti-inflammatory effects on diet-induced human-CRP and NFκB in vivo

scientific article published on 08 January 2014

Epitope specificity determines pathogenicity and detectability in ANCA-associated vasculitis ⬇️

scientific article published on March 15, 2013

Exogenous alpha-1-acid glycoprotein protects against renal ischemia-reperfusion injury by inhibition of inflammation and apoptosis.

scientific article published in October 2004

Expression of iNOS, eNOS, and peroxynitrite-modified proteins in experimental anti-myeloperoxidase associated crescentic glomerulonephritis

scientific article published on 01 February 1998

Genetic analysis of mesangial matrix expansion in aging mice and identification of Far2 as a candidate gene.

scientific article published on 05 September 2013

Genetic loci of Staphylococcus aureus associated with anti-neutrophil cytoplasmic autoantibody (ANCA)-associated vasculitides

scientific article published on 22 September 2017

Hematopoietic NF- B1 deficiency results in small atherosclerotic lesions with an inflammatory phenotype

scientific article published on 25 September 2003

Hemorrhagic Shock-induced Endothelial Cell Activation in a Spontaneous Breathing and a Mechanical Ventilation Hemorrhagic Shock Model Is Induced by a Proinflammatory Response and Not by Hypoxia

scientific article published on 01 September 2011

High mobility group box 1 skews macrophage polarization and negatively influences phagocytosis of apoptotic cells.

scientific article

IgG glycan hydrolysis attenuates ANCA-mediated glomerulonephritis.

scientific article

In reply to 'rituximab and B-cell return in ANCA-associated vasculitis'

scientific article published on 01 June 2014

Increased expression of Toll-like receptors by monocytes and natural killer cells in ANCA-associated vasculitis

scientific article

Increased expression of inducible nitric oxide synthase in circulating monocytes from patients with active inflammatory bowel disease

scientific article published on 01 May 2002

Increased frequency of circulating IL-21 producing Th-cells in patients with granulomatosis with polyangiitis (GPA).

scientific article

Inhibition of complement factor C5 protects against anti-myeloperoxidase antibody-mediated glomerulonephritis in mice

scientific article published on 14 February 2007

Inhibition of complement factor C5 protects against renal ischemia-reperfusion injury: inhibition of late apoptosis and inflammation.

scientific article published in February 2003

Inhibition of high-mobility group box 1 as therapeutic option in autoimmune disease: lessons from animal models

scientific article published on March 2013

Inhibition of neutrophil-mediated production of reactive oxygen species (ROS) by endothelial cells is not impaired in anti-neutrophil cytoplasmic autoantibodies (ANCA)-associated vasculitis patients.

scientific article published on 7 May 2010

Intermediate monocytes in ANCA vasculitis: increased surface expression of ANCA autoantigens and IL-1β secretion in response to anti-MPO antibodies

scientific article published on 7 July 2015

Intracellular RIG-I Signaling Regulates TLR4-Independent Endothelial Inflammatory Responses to Endotoxin.

scientific article published on 29 April 2016

Intrinsic renal cell and leukocyte-derived TLR4 aggravate experimental anti-MPO glomerulonephritis.

scientific article published on 15 September 2010

Involvement of MicroRNAs in the Aging-Related Decline of CD28 Expression by Human T Cells.

scientific article published on 18 June 2018

Involvement of Monocyte Subsets in the Immunopathology of Giant Cell Arteritis

scientific article published on 26 July 2017

Kv1.3 Channel Blockade Modulates the Effector Function of B Cells in Granulomatosis with Polyangiitis

scientific article published on 26 September 2017

L8. Animal models of ANCA associated vasculitis: the contribution of autoantibodies and autoreactive T cells.

scientific article published on 28 February 2013

Lack of IL-17 Receptor A signaling aggravates lymphoproliferation in C57BL/6 lpr mice

scientific article published on 11 March 2019

Leukocyte CD40L deficiency affects the CD25(+) CD4 T cell population but does not affect atherosclerosis

scientific article published on 05 July 2005

Low anti-staphylococcal IgG responses in granulomatosis with polyangiitis patients despite long-term Staphylococcus aureus exposure

scientific article

Low-Fat Diet With Caloric Restriction Reduces White Matter Microglia Activation During Aging

scientific article published on 12 March 2018

M2 macrophage is the predominant phenotype in airways inflammatory lesions in patients with granulomatosis with polyangiitis

scientific article

Mechanisms of ANCA-mediated leukocyte-endothelial cell interactions in vivo.

scientific article published on 27 February 2008

Mechanisms of Disease: pathogenesis and treatment of ANCA-associated vasculitides.

scientific article published on December 2006

Mechanisms of vasculitis: how pauci-immune is ANCA-associated renal vasculitis?

scientific article published on 01 January 2007

MicroRNA-126 contributes to renal microvascular heterogeneity of VCAM-1 protein expression in acute inflammation.

scientific article

Mirtoselect, an anthocyanin-rich bilberry extract, attenuates non-alcoholic steatohepatitis and associated fibrosis in ApoE(∗)3Leiden mice

scientific article published on 13 December 2014

Myeloperoxidase and serum amyloid A contribute to impaired in vivo reverse cholesterol transport during the acute phase response but not group IIA secretory phospholipase A(2)

scientific article

Myeloperoxidase attracts neutrophils by physical forces

scientific article published on 27 October 2010

Myeloperoxidase deficiency attenuates lipopolysaccharide-induced acute lung inflammation and subsequent cytokine and chemokine production

scientific article published on 01 June 2009

Myeloperoxidase modulates lung epithelial responses to pro-inflammatory agents

scientific article published on 05 December 2007

Myeloperoxidase: molecular mechanisms of action and their relevance to human health and disease.

scientific article

Neutrophil myeloperoxidase activity and the influence of two single-nucleotide promoter polymorphisms

scientific article published on 01 November 2003

Neutrophil myeloperoxidase harbors distinct site-specific peculiarities in its glycosylation

scientific article published on 12 November 2019

Nitric Oxide Inhibition Enhances Platelet Aggregation in Experimental Anti-Thy-1 Nephritis ⬇️

scientific article published on December 1, 2001

Obesity-induced chronic inflammation in high fat diet challenged C57BL/6J mice is associated with acceleration of age-dependent renal amyloidosis

scientific article

Opposite Regulation of Type II and III Receptors for Immunoglobulin G in Mouse Glomerular Mesangial Cells and in the Induction of Anti-glomerular Basement Membrane (GBM) Nephritis

scientific article published in Journal of Biological Chemistry

Pathogenesis of ANCA-associated vasculitis: new possibilities for intervention.

scientific article published on 28 June 2013

Pathogenesis of ANCA-associated vasculitis: recent insights from animal models

scientific article published on January 2012

Pathogenesis of vasculitis

scientific article published on 01 January 1998

Pathophysiology of ANCA-associated vasculitides: are ANCA really pathogenic?

scientific article

Phenotypic, transcriptomic and functional profiling reveal reduced activation thresholds of CD8+ T cells in giant cell arteritis

scientific article published in 2022

Pleiotropic effects of angiopoietin-2 deficiency do not protect mice against endotoxin-induced acute kidney injury

scientific article published on 07 August 2012

Positron emission tomography (PET) and single photon emission computed tomography (SPECT) imaging of macrophages in large vessel vasculitis: Current status and future prospects

scientific article published on 03 May 2018

Prospective monitoring of in vitro produced PR3-ANCA does not improve relapse prediction in granulomatosis with polyangiitis.

scientific article published on 3 August 2017

Protective effect of rosiglitazone on kidney function in high-fat challenged human-CRP transgenic mice: a possible role for adiponectin and miR-21?

scientific article published on 6 June 2017

Protective role of endothelial nitric oxide synthase

scientific article (publication date: 2003)

Reactivity against complementary proteinase-3 is not increased in patients with PR3-ANCA-associated vasculitis.

scientific article

Reduced levels of cytosolic DNA sensor AIM2 are associated with impaired cytokine responses in healthy elderly.

scientific article

Regulatory and effector B cell cytokine production in patients with relapsing granulomatosis with polyangiitis.

scientific article published on 4 April 2016

Relationship between myeloperoxidase promotor polymorphism and disease severity in sarcoidosis.

scientific article published on August 2003

Releasing the complement brakes: is myeloperoxidase the missing link between factor H and C5a in anti-neutrophil cytoplasmic antibody vasculitis?

scientific article published on 01 December 2018

Renal Klotho is Reduced in Septic Patients and Pretreatment With Recombinant Klotho Attenuates Organ Injury in Lipopolysaccharide-Challenged Mice

scientific article published on 01 December 2018

Review article: Pathogenic role of complement activation in anti-neutrophil cytoplasmic auto-antibody-associated vasculitis.

scientific article published on February 2009

Review: What Is the Current Evidence for Disease Subsets in Giant Cell Arteritis?

scientific article published on 30 July 2018

Role of oxidized low-density lipoprotein in renal disease.

scientific article

Site-Specific Inhibition of Glomerulonephritis Progression by Targeted Delivery of Dexamethasone to Glomerular Endothelium

scientific article published on 23 April 2007

Sustained protective effects of 7-monohydroxyethylrutoside in an in vivo model of cardiac ischemia-reperfusion.

scientific article

Systemic vasculitis developed after immune checkpoint inhibition: comment on the article by Cappelli et al

scientific article published on 01 August 2018

T cells in vascular inflammatory diseases

scientific article

The net effect of ANCA on neutrophil extracellular trap formation

scientific article published on 01 July 2018

The renal angiopoietin/Tie2 system in lethal human sepsis

scientific article published on 31 March 2014

Toll-like receptor 9 activation enhances B cell activating factor and interleukin-21 induced anti-proteinase 3 autoantibody production in vitro.

scientific article published on 28 August 2015

Towards precision medicine in ANCA-associated vasculitis

scientific article published on 17 October 2017

Transforming growth factor-beta mediates balance between inflammation and fibrosis during plaque progression

scientific article published on 01 June 2002

Treatment with anti-HMGB1 monoclonal antibody does not affect lupus nephritis in MRL/lpr mice

scientific article published on 13 January 2016

Unraveling the identity of FoxP3+ regulatory T cells in Granulomatosis with Polyangiitis patients.

scientific article published on 4 June 2019

Urinary Soluble CD163 in Active Renal Vasculitis

scientific article

Urinary and serum soluble CD25 complements urinary soluble CD163 to detect active renal anti-neutrophil cytoplasmic autoantibody-associated vasculitis: a cohort study

scientific article published in March 2018

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