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List of works by Satoshi Uchida

A chemically unmodified agonistic DNA with growth factor functionality for in vivo therapeutic application

scientific article published on 01 April 2020

A tadpole-shaped gene carrier with distinct phase segregation in a ternary polymeric micelle

scientific article published on 01 April 2015

Acidic pH-responsive siRNA conjugate for reversible carrier stability and accelerated endosomal escape with reduced IFNα-associated immune response.

scientific article published on 29 April 2013

An injectable spheroid system with genetic modification for cell transplantation therapy.

scientific article published on 31 December 2013

Bundling mRNA Strands to Prepare Nano-Assemblies with Enhanced Stability Towards RNase for In Vivo Delivery

scientific article published on 04 July 2019

Bundling of mRNA strands inside polyion complexes improves mRNA delivery efficiency in vitro and in vivo

scientific article published on 24 August 2020

Combination of chondroitin sulfate and polyplex micelles from Poly(ethylene glycol)-poly{N’-[N-(2-aminoethyl)-2-aminoethyl]aspartamide} block copolymer for prolonged in vivo gene transfection with reduced toxicity ⬇️

scientific article published on May 5, 2011

Design concepts of polyplex micelles for in vivo therapeutic delivery of plasmid DNA and messenger RNA

scientific article published on 31 January 2019

Designing immunostimulatory double stranded messenger RNA with maintained translational activity through hybridization with poly A sequences for effective vaccination.

scientific article published on 27 September 2017

Development of Biodegradable Polycation-Based Inhalable Dry Gene Powders by Spray Freeze Drying

scientific article

Enhancement of Motor Function Recovery after Spinal Cord Injury in Mice by Delivery of Brain-Derived Neurotrophic Factor mRNA

scientific article published on 29 June 2019

Gene Transfection toward Spheroid Cells on Micropatterned Culture Plates for Genetically-modified Cell Transplantation.

scientific article published on 31 July 2015

Gene transfection to spheroid culture system on micropatterned culture plate by polyplex nanomicelle: a novel platform of genetically-modified cell transplantation

scientific article published in October 2012

Glycaemic control boosts glucosylated nanocarrier crossing the BBB into the brain

scientific article published on 17 October 2017

Homo-catiomer integration into PEGylated polyplex micelle from block-catiomer for systemic anti-angiogenic gene therapy for fibrotic pancreatic tumors.

scientific article

In vivo messenger RNA introduction into the central nervous system using polyplex nanomicelle

scientific article

Induced packaging of mRNA into polyplex micelles by regulated hybridization with a small number of cholesteryl RNA oligonucleotides directed enhanced in vivo transfection

scientific article published on 17 January 2019

Intrathecal injection of a therapeutic gene-containing polyplex to treat spinal cord injury

scientific article

Messenger RNA-based therapeutics for brain diseases: An animal study for augmenting clearance of beta-amyloid by intracerebral administration of neprilysin mRNA loaded in polyplex nanomicelles.

scientific article published on 6 June 2016

Messenger RNA-based therapeutics for the treatment of apoptosis-associated diseases

scientific article

Muscle-targeted hydrodynamic gene introduction of insulin-like growth factor-1 using polyplex nanomicelle to treat peripheral nerve injury.

scientific article published on 20 March 2014

Optimized rod length of polyplex micelles for maximizing transfection efficiency and their performance in systemic gene therapy against stroma-rich pancreatic tumors.

scientific article published on 8 April 2014

PEG-OligoRNA Hybridization of mRNA for Developing Sterically Stable Lipid Nanoparticles toward In Vivo Administration

scientific article published on 03 April 2019

PEGylated Polyplex With Optimized PEG Shielding Enhances Gene Introduction in Lungs by Minimizing Inflammatory Responses ⬇️

scientific article published on February 14, 2012

Polyplex Micelles with Phenylboronate/Gluconamide Cross-Linking in the Core Exerting Promoted Gene Transfection through Spatiotemporal Responsivity to Intracellular pH and ATP Concentration.

scientific article published on 30 November 2017

Polyplex micelle installing intracellular self-processing functionalities without free catiomers for safe and efficient systemic gene therapy through tumor vasculature targeting

scientific article

Precise tuning of disulphide crosslinking in mRNA polyplex micelles for optimising extracellular and intracellular nuclease tolerability

scientific article published on 05 April 2019

Prolonged engraftment of transplanted hepatocytes in the liver by transient pro-survival factor supplementation using ex vivo mRNA transfection

scientific article published on 30 June 2018

Screening of mRNA Chemical Modification to Maximize Protein Expression with Reduced Immunogenicity.

scientific article published on 23 July 2015

Single-Stranded DNA-Packaged Polyplex Micelle as Adeno-Associated-Virus-Inspired Compact Vector to Systemically Target Stroma-Rich Pancreatic Cancer

scientific article published on 31 October 2019

Systemic Delivery of Folate-PEG siRNA Lipopolyplexes with Enhanced Intracellular Stability for In Vivo Gene Silencing in Leukemia

scientific article

Targeted gene delivery by polyplex micelles with crowded PEG palisade and cRGD moiety for systemic treatment of pancreatic tumors

scientific article published on 15 January 2014

Toroidal Packaging of pDNA into Block Ionomer Micelles Exerting Promoted in Vivo Gene Expression.

scientific article published on 30 July 2015

Transient stealth coating of liver sinusoidal wall by anchoring two-armed PEG for retargeting nanomedicines

scientific article published on 26 June 2020

Treatment of Bone Defects by Transplantation of Genetically Modified Mesenchymal Stem Cell Spheroids

scientific article published on 18 April 2018

Treatment of Intervertebral Disk Disease by the Administration of mRNA Encoding a Cartilage-Anabolic Transcription Factor

scientific article published on 22 February 2019

Treatment of spinal cord injury by an advanced cell transplantation technology using brain-derived neurotrophic factor-transfected mesenchymal stem cell spheroids.

scientific article

Tunable nonenzymatic degradability of N-substituted polyaspartamide main chain by amine protonation and alkyl spacer length in side chains for enhanced messenger RNA transfection efficiency

scientific article published on 13 February 2019

mRNA as a Tool for Gene Transfection in 3D Cell Culture for Future Regenerative Therapy

scientific article published on 18 April 2020

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