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List of works by Alvina G Lai

A TALE of shrimps: Genome-wide survey of homeobox genes in 120 species from diverse crustacean taxa.

scientific article

A dual role for SAMHD1 in regulating HBV cccDNA and RT-dependent particle genesis

scientific article published on 27 March 2019

A novel signature derived from immunoregulatory and hypoxia genes predicts prognosis in liver and five other cancers

article

An immunoevasive strategy through clinically-relevant pan-cancer genomic and transcriptomic alterations of JAK-STAT signaling components

scientific article published on 04 November 2019

An integrative pan-cancer investigation reveals common genetic and transcriptional alterations of AMPK pathway genes as important predictors of clinical outcomes across major cancer types

scientific article published on 17 August 2020

Antithrombotic therapy in patients with liver disease: population-based insights on variations in prescribing trends, adherence, persistence and impact on stroke and bleeding

scientific article published on 08 September 2021

COVID-19 trajectories among 57 million adults in England: a cohort study using electronic health records

scientific article published in 2022

Comparative genomic analysis of crustacean hyperglycemic hormone (CHH) neuropeptide genes across diverse crustacean species

article

Comparative genomic analysis of innate immunity reveals novel and conserved components in crustacean food crop species.

scientific article

Conservation of epigenetic regulation by the MLL3/4 tumour suppressor in planarian pluripotent stem cells

scientific article published in Nature Communications

Coordinated transcriptional regulation between a reactive oxygen species-responsive gene network and the circadian clock in Arabidopsis thaliana

2012 doctoral thesis by Alvina Grace Lai at Massey University

Could ROS signals drive tissue-specific clocks?

scientific article published on September 2013

Daytime variation in hepatitis C virus replication kinetics following liver transplant

scientific article published on 20 September 2018

Dual prognostic role of 2-oxoglutarate-dependent oxygenases in ten cancer types: implications for cell cycle regulation and cell adhesion maintenance

scientific article published on 29 April 2019

Epigenetic analyses of planarian stem cells demonstrate conservation of bivalent histone modifications in animal stem cells

scientific article published on 24 August 2018

Estimated impact of the COVID-19 pandemic on cancer services and excess 1-year mortality in people with cancer and multimorbidity: near real-time data on cancer care, cancer deaths and a population-based cohort study

scientific article published on 17 November 2020

EvoRegen in Animals: Time to uncover deep conservation or convergence of adult stem cell evolution and regenerative processes

scientific article

Genome-wide analyses of the bHLH superfamily in crustaceans: reappraisal of higher-order groupings and evidence for lineage-specific duplications.

scientific article

Glucose and glutamine availability regulate HepG2 transcriptional responses to low oxygen

article

Increased burden of cardiovascular disease in people with liver disease: unequal geographical variations, risk factors and excess years of life lost

scientific article published on 03 January 2022

Interplay between circadian clock and viral infection.

scientific article published on 30 September 2017

Linked electronic health records for research on a nationwide cohort of more than 54 million people in England: data resource

scientific article published on 07 April 2021

Mixed evolutionary origins of endogenous biomass-depolymerizing enzymes in animals.

scientific article

Pan-cancer genomic amplifications underlie a WNT hyperactivation phenotype associated with stem cell-like features leading to poor prognosis

scientific article published on 22 April 2019

Positional information resolves structural variations and uncovers an evolutionarily divergent genetic locus in accessions of Arabidopsis thaliana.

scientific article

The abrogation of condensin function provides independent evidence for defining the self-renewing population of pluripotent stem cells.

scientific article

The circadian clock components BMAL1 and REV-ERBα regulate flavivirus replication

scientific article published in Nature Communications

The genome of the crustacean Parhyale hawaiensis, a model for animal development, regeneration, immunity and lignocellulose digestion

scientific article

The pan-cancer mutational landscape of the PPAR pathway reveals universal patterns of dysregulated metabolism and interactions with tumor immunity and hypoxia

scientific article published on 19 June 2019

The protein subunit of telomerase displays patterns of dynamic evolution and conservation across different metazoan taxa.

scientific article

Timing gone awry: distinct tumour suppressive and oncogenic roles of the circadian clock and crosstalk with hypoxia signalling in diverse malignancies

scientific article published on 23 April 2019

Transcriptional landscape of DNA repair genes underpins a pan-cancer prognostic signature associated with cell cycle dysregulation and tumor hypoxia

scientific article published on 24 April 2019