List of works by Michael V Holmes

Adult height, coronary heart disease and stroke: a multi-locus Mendelian randomization meta-analysis

scientific article published in December 2016

Association between alcohol and cardiovascular disease: Mendelian randomisation analysis based on individual participant data

scientific article

Association of Chromosome 9p21 With Subsequent Coronary Heart Disease Events

scientific article published on 21 March 2019

Associations of General and Central Adiposity With Incident Diabetes in Chinese Men and Women

scientific article published on 3 January 2018

Blood pressure loci identified with a gene-centric array

scientific article

Body muscle gain and markers of cardiovascular disease susceptibility in young adulthood: A cohort study

scientific article published in 2021

Bone mineral density and risk of type 2 diabetes and coronary heart disease: A Mendelian randomization study.

scientific article published on 22 August 2017

CETP inhibition and ADCY9 genotype: evidence of a qualitative pharmacogenetic interaction in cardiovascular disease?

article

Causal Associations of Adiposity and Body Fat Distribution with Coronary Heart Disease, Stroke Subtypes and Type 2 Diabetes: A Mendelian Randomization Analysis

scientific article

Causal relationships between obesity and the leading causes of death in women and men

scientific article published on 24 October 2019

Causal relevance of blood lipid fractions in the development of carotid atherosclerosis: Mendelian randomization analysis

scientific article published on 28 December 2012

Characterising metabolomic signatures of lipid-modifying therapies through drug target mendelian randomisation

scientific article published on 25 February 2022

Commentary: Mendelian randomization and women's health

scientific article published on 01 June 2019

Correction: Population Genomics of Cardiometabolic Traits: Design of the University College London-London School of Hygiene and Tropical Medicine-Edinburgh-Bristol (UCLEB) Consortium.

scientific article published on 24 September 2013

Cystatin C and Cardiovascular Disease: A Mendelian Randomization Study

scientific article

Effect modification by population dietary folate on the association between MTHFR genotype, homocysteine, and stroke risk: a meta-analysis of genetic studies and randomised trials

scientific article

Evaluating the cardiovascular safety of sclerostin inhibition using evidence from meta-analysis of clinical trials and human genetics

scientific article published on 01 June 2020

Evaluating the relationship between circulating lipoprotein lipids and apolipoproteins with risk of coronary heart disease: A multivariable Mendelian randomisation analysis

scientific article published on 23 March 2020

GWAS identifies 10 loci for objectively-measured physical activity and sleep with causal roles in cardiometabolic disease

Gene-centric meta-analysis in 87,736 individuals of European ancestry identifies multiple blood-pressure-related loci

scientific article published on 20 February 2014

Genetic Predisposition to Type 2 Diabetes and Risk of Subclinical Atherosclerosis and Cardiovascular Diseases Among 160,000 Chinese Adults

scientific article published on 09 August 2019

Genetic Support for a Causal Role of Insulin Resistance on Circulating Branched-Chain Amino Acids and Inflammation

scientific article

Genome-wide association and Mendelian randomisation analysis provide insights into the pathogenesis of heart failure

scientific article published on 09 January 2020

Genomic and drug target evaluation of 90 cardiovascular proteins in 30,931 individuals

scientific article published on 16 October 2020

Guidelines for performing Mendelian randomization investigations

scientific article published on 26 November 2019

HMG-coenzyme A reductase inhibition, type 2 diabetes, and bodyweight: evidence from genetic analysis and randomised trials

scientific article published on 24 September 2014

Harnessing publicly available genetic data to prioritize lipid modifying therapeutic targets for prevention of coronary heart disease based on dysglycemic risk

scientific article

Influence of puberty timing on adiposity and cardiometabolic traits: A Mendelian randomisation study

scientific article published in August 2018

Interleukin-6 receptor pathways in abdominal aortic aneurysm

scientific article published on 30 October 2012

Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci

scientific article

Lipoprotein signatures of cholesteryl ester transfer protein and HMG-CoA reductase inhibition

scientific article published on 20 December 2019

Mendel's laws, Mendelian randomization and causal inference in observational data: substantive and nomenclatural issues

scientific article published on 01 February 2020

Mendelian randomization of blood lipids for coronary heart disease

scientific article

Novel genetic approach to investigate the role of plasma secretory phospholipase A2 (sPLA2)-V isoenzyme in coronary heart disease: modified Mendelian randomization analysis using PLA2G5 expression levels

scientific article

PCSK9 genetic variants and risk of type 2 diabetes: a mendelian randomisation study

scientific article published on 28 November 2016

PCSK9 genetic variants, life-long lowering of LDL-cholesterol and cognition: a large-scale Mendelian randomization study

PLA2G10 Gene Variants, sPLA2 Activity, and Coronary Heart Disease Risk

scientific article published on 12 January 2015

Phenome-wide association analysis of LDL-cholesterol lowering genetic variants in PCSK9

scientific article published on 29 October 2019

Plasma urate concentration and risk of coronary heart disease: a Mendelian randomisation analysis

scientific article published on 15 January 2016

Polygenic risk scores and the prediction of common diseases

scientific article published on 01 February 2020

Population genomics of cardiometabolic traits: design of the University College London-London School of Hygiene and Tropical Medicine-Edinburgh-Bristol (UCLEB) Consortium

scientific article (publication date: 2013)

Relations between lipoprotein(a) concentrations, LPA genetic variants, and the risk of mortality in patients with established coronary heart disease: a molecular and genetic association study

scientific article published on 26 May 2017

Secretory phospholipase A(2)-IIA and cardiovascular disease: a mendelian randomization study

scientific article published on 31 July 2013

Sex Differences in the Risk of Coronary Heart Disease Associated With Type 2 Diabetes: A Mendelian Randomization Analysis

scientific article published on 04 December 2020

Sixty-five common genetic variants and prediction of type 2 diabetes

scientific article published on 4 December 2014

Subsequent Event Risk in Individuals With Established Coronary Heart Disease

scientific article published on 21 March 2019

The interleukin-6 receptor as a target for prevention of coronary heart disease: a mendelian randomisation analysis

scientific article published on 14 March 2012

Using human genetics to guide the repurposing of medicines

scientific article published on 25 February 2020

Variability in aspirin efficacy: all in the genes?

scientific article published on 01 November 2019

What is 'LDL cholesterol'?

scientific article published on 01 April 2019

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