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List of works by Jérôme Braudeau

Activation of proinflammatory caspases by cathepsin B in focal cerebral ischemia

scientific article published on 01 November 2004

Alzheimer's disease-like APP processing in wild-type mice identifies synaptic defects as initial steps of disease progression

scientific article

CYP46A1 inhibition, brain cholesterol accumulation and neurodegeneration pave the way for Alzheimer's disease.

scientific article published on 2 July 2015

Cholesterol 24-hydroxylase defect is implicated in memory impairments associated with Alzheimer-like Tau pathology.

scientific article

Chronic Treatment with a Promnesiant GABA-A α5-Selective Inverse Agonist Increases Immediate Early Genes Expression during Memory Processing in Mice and Rectifies Their Expression Levels in a Down Syndrome Mouse Model

scientific article

Interleukin-2 improves amyloid pathology, synaptic failure and memory in Alzheimer's disease mice.

scientific article published on 20 December 2016

Is it time to rethink the Alzheimer's disease drug development strategy by targeting its silent phase?

scientific article

PTD-XIAP protects against cerebral ischemia by anti-apoptotic and transcriptional regulatory mechanisms.

scientific article published on 19 December 2005

Reducing GABAergic inhibition restores cognitive functions in a mouse model of Down syndrome

scientific article published on February 2014

Specific targeting of the GABA-A receptor α5 subtype by a selective inverse agonist restores cognitive deficits in Down syndrome mice

scientific article

The mechanisms of cell death in focal cerebral ischemia highlight neuroprotective perspectives by anti-caspase therapy.

scientific article

Transient increase in sAPPα secretion in response to Aβ1-42 oligomers: an attempt of neuronal self-defense?

scientific article published on 19 September 2017

Viral gene transfer of APPsα rescues synaptic failure in an Alzheimer's disease mouse model.

scientific article published on 4 November 2015

βAPP Processing Drives Gradual Tau Pathology in an Age-Dependent Amyloid Rat Model of Alzheimer's Disease.

scientific article

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