List of works - Ian F Hermans

5,6-Dimethylxanthenone-4-acetic acid treatment of a non-immunogenic tumour does not synergize with active or passive CD8+ T-cell immunotherapy

scientific article published on August 2006

A phase I vaccination study with dendritic cells loaded with NY-ESO-1 and α-galactosylceramide: induction of polyfunctional T cells in high-risk melanoma patients

scientific article published in November 2017

A self-adjuvanting vaccine induces cytotoxic T lymphocytes that suppress allergy.

scientific article published on 05 October 2014

Activated NKT Cells Can Condition Different Splenic Dendritic Cell Subsets To Respond More Effectively to TLR Engagement and Enhance Cross-Priming

scientific article published on 15 June 2015

Activation of Human Mucosal-Associated Invariant T Cells Induces CD40L-Dependent Maturation of Monocyte-Derived and Primary Dendritic Cells.

scientific article published on 6 September 2017

Administration of alpha-galactosylceramide impairs the survival of dendritic cell subpopulations in vivo

scientific article published on 4 February 2011

An adjuvanted whole cell vaccine as post-remission immunotherapy for acute leukemia.

scientific article published on 22 January 2015

An autologous leukemia cell vaccine prevents murine acute leukemia relapse after cytarabine treatment

scientific article published on 18 September 2014

An improved synthesis of dansylated α-galactosylceramide and its use as a fluorescent probe for the monitoring of glycolipid uptake by cells

scientific article published in May 2011

Assessment of DNA fingerprinting for determining genetic diversity in sheep populations

scientific article published on 24 April 2009

Augmenting Influenza-Specific T Cell Memory Generation with a Natural Killer T Cell-Dependent Glycolipid-Peptide Vaccine

scientific article published on 18 October 2017

Autologous dendritic cells pulsed with eluted peptide as immunotherapy for advanced B-cell malignancies

scientific article published in April 2006

B-Lymphocytes activated by CD40 ligand induce an antigen-specific anti-tumour immune response by direct and indirect activation of CD8(+) T-cells.

scientific article

Batf3-independent langerin- CX3CR1- CD8α+ splenic DCs represent a precursor for classical cross-presenting CD8α+ DCs.

scientific article published on 28 August 2014

Blocking CTLA-4 while priming with a whole cell vaccine reshapes the oligoclonal T cell infiltrate and eradicates tumors in an orthotopic glioma model

scientific article published on 27 September 2017

CD8+ T Cell-Dependent Elimination of Dendritic Cells In Vivo Limits the Induction of Antitumor Immunity

scientific article published on 15 March 2000

Competition Between CTL Narrows the Immune Response Induced by Prime-Boost Vaccination Protocols

scientific article published in May 2002

CpG-matured murine plasmacytoid dendritic cells are capable of in vivo priming of functional CD8 T cell responses to endogenous but not exogenous antigens

scientific article

Cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) can regulate dendritic cell-induced activation and cytotoxicity of CD8(+) T cells independently of CD4(+) T cell help.

scientific article published on April 1999

Dendritic Cell-Based Vaccines

scientific article published in November 2014

Dendritic cell elimination as an assay of cytotoxic T lymphocyte activity in vivo

scientific article published in December 2000

Dendritic cell function can be modulated through cooperative actions of TLR ligands and invariant NKT cells

article by Ian F Hermans et al published 20 February 2007 in Journal of Immunology

Dendritic cell vaccination combined with temozolomide retreatment: results of a phase I trial in patients with recurrent glioblastoma multiforme

scientific article published on 31 October 2014

Dendritic cells treated with lipopolysaccharide up-regulate serine protease inhibitor 6 and remain sensitive to killing by cytotoxic T lymphocytes in vivo

scientific article published on December 2008

Dendritic cells: a journey from laboratory to clinic

scientific article published on January 2004

Determining mean fractional anisotropy using DDCOSY: preliminary results in biological tissues

scientific article published on 2 August 2016

Distinct Dysfunctional States of Circulating Innate-Like T Cells in Metabolic Disease

scientific article published on 13 March 2020

Effects of treatment changes on asthma phenotype prevalence and airway neutrophil function

scientific article published on 4 December 2017

Efficient depletion of chronic lymphocytic leukemia B cells using serial rounds of immunomagnetic depletion

scientific article published on 31 July 2013

Engaging Natural Killer T Cells as 'Universal Helpers' for Vaccination

scientific article published on 22 December 2016

Enhanced immunosuppression by therapy-exposed glioblastoma multiforme tumor cells

scientific article published on 12 November 2014

Enhancing T cell responses and tumour immunity by vaccination with peptides conjugated to a weak NKT cell agonist

scientific article published in 2019

Erratum: Roles of tumour localization, second signals and cross priming in cytotoxic T-cell induction

scientific article published in September 2001

Exploiting invariant NKT cells to promote T-cell responses to cancer vaccines

scientific article published in April 2013

Exploiting the role of endogenous lymphoid-resident dendritic cells in the priming of NKT cells and CD8+ T cells to dendritic cell-based vaccines

scientific article (publication date: 31 March 2011)

Expression of CD1a and Type-1 Polarization Are Dissociated in Human Monocyte-Derived Dendritic Cells

scientific article published on 13 October 2015

Functional invariant natural killer T-cell and CD1d axis in chronic lymphocytic leukemia: implications for immunotherapy

scientific article published on 12 October 2012

Glycolipid-peptide conjugate vaccines enhance CD8+ T cell responses against human viral proteins

scientific article published on 27 October 2017

Glycolipid-peptide vaccination induces liver-resident memory CD8+ T cells that protect against rodent malaria

scientific article published on 01 June 2020

Glycolipids injected into the skin are presented to NKT cells in the draining lymph node independently of migratory skin dendritic cells.

scientific article published in June 2009

High avidity antigen-specific CTL identified by CD8-independent tetramer staining

scientific article published on November 2003

Hot-injection synthesis of iron/iron oxide core/shell nanoparticles for T2 contrast enhancement in magnetic resonance imaging

scientific article published in 2011

Identifying leukocyte populations in fresh and cryopreserved sputum using flow cytometry

scientific article published on 22 January 2013

Immature murine NKT cells pass through a stage of developmentally programmed innate IL-4 secretion.

scientific article published on 31 August 2012

Increasing the Survival of Dendritic Cells In Vivo Does Not Replace the Requirement for CD4+ T Cell Help during Primary CD8+ T Cell Responses

scientific article published on 18 October 2007

Invariant natural killer T cells and asthma: Immunologic reality or methodologic artifact?

article

Langerin+ CD8alpha+ dendritic cells are critical for cross-priming and IL-12 production in response to systemic antigens

scientific article published in December 2009

Langerin+ CD8α+ Dendritic Cells Drive Early CD8+ T Cell Activation and IL-12 Production During Systemic Bacterial Infection.

scientific article published on 7 May 2018

MIS416, a non-toxic microparticle adjuvant derived from Propionibacterium acnes comprising immunostimulatory muramyl dipeptide and bacterial DNA promotes cross-priming and Th1 immunity

scientific article published on 27 October 2010

Mucosal-Associated Invariant T (MAIT) Cell Dysfunction and PD-1 Expression in Prostate Cancer: Implications for Immunotherapy

scientific article published on 19 October 2021

Mānuka honey-derived methylglyoxal enhances microbial sensing by mucosal-associated invariant T cells

scientific article published on 03 July 2020

NKT cell-dependent glycolipid-peptide vaccines with potent anti-tumour activity

scientific article published on 25 June 2015

NKT cells enhance CD4+ and CD8+ T cell responses to soluble antigen in vivo through direct interaction with dendritic cells

scientific article published on November 2003

Novel synthesis of alpha-galactosyl-ceramides and confirmation of their powerful NKT cell agonist activity

scientific article published on 02 October 2006

Perforin-dependent elimination of dendritic cells regulates the expansion of antigen-specific CD8+ T cells in vivo

scholarly article

Poly Ethoxy Ethyl Glycinamide (PEE-G) Dendrimers: Dendrimers Specifically Designed for Pharmaceutical Applications

scientific article published on 8 July 2016

Potent anti-tumor responses to immunization with dendritic cells loaded with tumor tissue and an NKT cell ligand

scientific article published on 9 February 2010

Side population is not necessary or sufficient for a cancer stem cell phenotype in glioblastoma multiforme

scientific article published in March 2011

Simple Synthesis and Functionalization of Iron Nanoparticles for Magnetic Resonance Imaging

scientific article published on 6 April 2011

Species-Specific Activity of Glycolipid Ligands for Invariant NKT Cells

scientific article published on 25 May 2012

Splenic Dendritic Cells Involved in Cross-Tolerance of Tumor Antigens Can Play a Stimulatory Role in Adoptive T-Cell Therapy.

scientific article published on October 2015

Sputum basophils are increased in eosinophilic asthma compared with non-eosinophilic asthma phenotypes.

scientific article published on 20 April 2017

Stability of polyelectrolyte-coated iron nanoparticles for T 2 -weighted magnetic resonance imaging

scientific article published in October 2017

Strongly magnetic iron nanoparticles improve the diagnosis of small tumours in the reticuloendothelial system by magnetic resonance imaging

scientific article

Sustained in vivo depletion of splenic langerin+ CD8α+ dendritic cells is well-tolerated by lang-DTREGFP mice

scientific article published in April 2014

Synergistic effect of metronomic dosing of cyclophosphamide combined with specific antitumor immunotherapy in a murine melanoma model.

scientific article published in December 2003

Synthesis and Activity of 6″-Deoxy-6″-thio-α-GalCer and Peptide Conjugates

scientific article published on 25 November 2015

Synthesis and Stability of Highly Crystalline and Stable Iron/Iron Oxide Core/Shell Nanoparticles for Biomedical Applications

scientific article published on 20 January 2012

Targeting antigen to MHC class II molecules promotes efficient cross-presentation and enhances immunotherapy

scientific article published in February 2009

The Chemical Synthesis, Stability, and Activity of MAIT Cell Prodrug Agonists That Access MR1 in Recycling Endosomes

scientific article published on 14 January 2020

The VITAL assay: a versatile fluorometric technique for assessing CTL- and NKT-mediated cytotoxicity against multiple targets in vitro and in vivo

scientific article (publication date: February 2004)

The control of CD8+ T cell responses is preserved in perforin-deficient mice and released by depletion of CD4+CD25+ regulatory T cells

scientific article published on 24 July 2013

Third-generation anti-CD19 chimeric antigen receptor T-cells incorporating a TLR2 domain for relapsed or refractory B-cell lymphoma: a phase I clinical trial protocol (ENABLE)

scientific article published on 09 February 2020

Three cases of disputed paternity in dogs resolved by the use of DNA fingerprinting

scientific article published in June 1991

Tumor immunotherapy by epicutaneous immunization requires langerhans cells.

scientific article published in February 2008

Tumor-peptide-pulsed dendritic cells isolated from spleen or cultured in vitro from bone marrow precursors can provide protection against tumor challenge.

scientific article published in August 1997

Using magnetic resonance imaging to evaluate dendritic cell-based vaccination

scientific article (publication date: 2013)

Utilizing the adjuvant properties of CD1d-dependent NK T cells in T cell-mediated immunotherapy

scientific article published on December 2004

Vaccination with irradiated tumor cells pulsed with an adjuvant that stimulates NKT cells is an effective treatment for glioma.

scientific article published on 12 November 2012

Vaccines adjuvanted with an NKT cell agonist induce effective T-cell responses in models of CNS lymphoma

scientific article published on 22 April 2020

Virus-like particles and α-galactosylceramide form a self-adjuvanting composite particle that elicits anti-tumor responses

scientific article published on 22 February 2012

Whole tumor cell vaccines for glioma immunotherapy

scientific article published in January 2016

List of works by Ian F Hermans

5,6-Dimethylxanthenone-4-acetic acid treatment of a non-immunogenic tumour does not synergize with active or passive CD8+ T-cell immunotherapy

A phase I vaccination study with dendritic cells loaded with NY-ESO-1 and α-galactosylceramide: induction of polyfunctional T cells in high-risk melanoma patients

A self-adjuvanting vaccine induces cytotoxic T lymphocytes that suppress allergy.

Activated NKT Cells Can Condition Different Splenic Dendritic Cell Subsets To Respond More Effectively to TLR Engagement and Enhance Cross-Priming

Activation of Human Mucosal-Associated Invariant T Cells Induces CD40L-Dependent Maturation of Monocyte-Derived and Primary Dendritic Cells.

Administration of alpha-galactosylceramide impairs the survival of dendritic cell subpopulations in vivo

An adjuvanted whole cell vaccine as post-remission immunotherapy for acute leukemia.

An autologous leukemia cell vaccine prevents murine acute leukemia relapse after cytarabine treatment

An improved synthesis of dansylated α-galactosylceramide and its use as a fluorescent probe for the monitoring of glycolipid uptake by cells

Assessment of DNA fingerprinting for determining genetic diversity in sheep populations

Augmenting Influenza-Specific T Cell Memory Generation with a Natural Killer T Cell-Dependent Glycolipid-Peptide Vaccine

Autologous dendritic cells pulsed with eluted peptide as immunotherapy for advanced B-cell malignancies

B-Lymphocytes activated by CD40 ligand induce an antigen-specific anti-tumour immune response by direct and indirect activation of CD8(+) T-cells.

Batf3-independent langerin- CX3CR1- CD8α+ splenic DCs represent a precursor for classical cross-presenting CD8α+ DCs.

Blocking CTLA-4 while priming with a whole cell vaccine reshapes the oligoclonal T cell infiltrate and eradicates tumors in an orthotopic glioma model

CD8+ T Cell-Dependent Elimination of Dendritic Cells In Vivo Limits the Induction of Antitumor Immunity

Competition Between CTL Narrows the Immune Response Induced by Prime-Boost Vaccination Protocols

CpG-matured murine plasmacytoid dendritic cells are capable of in vivo priming of functional CD8 T cell responses to endogenous but not exogenous antigens

Cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) can regulate dendritic cell-induced activation and cytotoxicity of CD8(+) T cells independently of CD4(+) T cell help.

Dendritic Cell-Based Vaccines

Dendritic cell elimination as an assay of cytotoxic T lymphocyte activity in vivo

Dendritic cell function can be modulated through cooperative actions of TLR ligands and invariant NKT cells

Dendritic cell vaccination combined with temozolomide retreatment: results of a phase I trial in patients with recurrent glioblastoma multiforme

Dendritic cells treated with lipopolysaccharide up-regulate serine protease inhibitor 6 and remain sensitive to killing by cytotoxic T lymphocytes in vivo

Dendritic cells: a journey from laboratory to clinic

Determining mean fractional anisotropy using DDCOSY: preliminary results in biological tissues

Distinct Dysfunctional States of Circulating Innate-Like T Cells in Metabolic Disease

Effects of treatment changes on asthma phenotype prevalence and airway neutrophil function

Efficient depletion of chronic lymphocytic leukemia B cells using serial rounds of immunomagnetic depletion

Engaging Natural Killer T Cells as 'Universal Helpers' for Vaccination

Enhanced immunosuppression by therapy-exposed glioblastoma multiforme tumor cells

Enhancing T cell responses and tumour immunity by vaccination with peptides conjugated to a weak NKT cell agonist

Erratum: Roles of tumour localization, second signals and cross priming in cytotoxic T-cell induction

Exploiting invariant NKT cells to promote T-cell responses to cancer vaccines

Exploiting the role of endogenous lymphoid-resident dendritic cells in the priming of NKT cells and CD8+ T cells to dendritic cell-based vaccines

Expression of CD1a and Type-1 Polarization Are Dissociated in Human Monocyte-Derived Dendritic Cells

Functional invariant natural killer T-cell and CD1d axis in chronic lymphocytic leukemia: implications for immunotherapy

Glycolipid-peptide conjugate vaccines enhance CD8+ T cell responses against human viral proteins

Glycolipid-peptide vaccination induces liver-resident memory CD8+ T cells that protect against rodent malaria

Glycolipids injected into the skin are presented to NKT cells in the draining lymph node independently of migratory skin dendritic cells.

High avidity antigen-specific CTL identified by CD8-independent tetramer staining

Hot-injection synthesis of iron/iron oxide core/shell nanoparticles for T2 contrast enhancement in magnetic resonance imaging

Identifying leukocyte populations in fresh and cryopreserved sputum using flow cytometry

Immature murine NKT cells pass through a stage of developmentally programmed innate IL-4 secretion.

Increasing the Survival of Dendritic Cells In Vivo Does Not Replace the Requirement for CD4+ T Cell Help during Primary CD8+ T Cell Responses

Invariant natural killer T cells and asthma: Immunologic reality or methodologic artifact?

Langerin+ CD8alpha+ dendritic cells are critical for cross-priming and IL-12 production in response to systemic antigens

Langerin+ CD8α+ Dendritic Cells Drive Early CD8+ T Cell Activation and IL-12 Production During Systemic Bacterial Infection.

MIS416, a non-toxic microparticle adjuvant derived from Propionibacterium acnes comprising immunostimulatory muramyl dipeptide and bacterial DNA promotes cross-priming and Th1 immunity

Mucosal-Associated Invariant T (MAIT) Cell Dysfunction and PD-1 Expression in Prostate Cancer: Implications for Immunotherapy

Mānuka honey-derived methylglyoxal enhances microbial sensing by mucosal-associated invariant T cells

NKT cell-dependent glycolipid-peptide vaccines with potent anti-tumour activity

NKT cells enhance CD4+ and CD8+ T cell responses to soluble antigen in vivo through direct interaction with dendritic cells

Novel synthesis of alpha-galactosyl-ceramides and confirmation of their powerful NKT cell agonist activity

Perforin-dependent elimination of dendritic cells regulates the expansion of antigen-specific CD8+ T cells in vivo

Poly Ethoxy Ethyl Glycinamide (PEE-G) Dendrimers: Dendrimers Specifically Designed for Pharmaceutical Applications

Potent anti-tumor responses to immunization with dendritic cells loaded with tumor tissue and an NKT cell ligand

Side population is not necessary or sufficient for a cancer stem cell phenotype in glioblastoma multiforme

Simple Synthesis and Functionalization of Iron Nanoparticles for Magnetic Resonance Imaging

Species-Specific Activity of Glycolipid Ligands for Invariant NKT Cells

Splenic Dendritic Cells Involved in Cross-Tolerance of Tumor Antigens Can Play a Stimulatory Role in Adoptive T-Cell Therapy.

Sputum basophils are increased in eosinophilic asthma compared with non-eosinophilic asthma phenotypes.

Stability of polyelectrolyte-coated iron nanoparticles for T 2 -weighted magnetic resonance imaging

Strongly magnetic iron nanoparticles improve the diagnosis of small tumours in the reticuloendothelial system by magnetic resonance imaging

Sustained in vivo depletion of splenic langerin+ CD8α+ dendritic cells is well-tolerated by lang-DTREGFP mice

Synergistic effect of metronomic dosing of cyclophosphamide combined with specific antitumor immunotherapy in a murine melanoma model.

Synthesis and Activity of 6″-Deoxy-6″-thio-α-GalCer and Peptide Conjugates

Synthesis and Stability of Highly Crystalline and Stable Iron/Iron Oxide Core/Shell Nanoparticles for Biomedical Applications

Targeting antigen to MHC class II molecules promotes efficient cross-presentation and enhances immunotherapy

The Chemical Synthesis, Stability, and Activity of MAIT Cell Prodrug Agonists That Access MR1 in Recycling Endosomes

The VITAL assay: a versatile fluorometric technique for assessing CTL- and NKT-mediated cytotoxicity against multiple targets in vitro and in vivo

The control of CD8+ T cell responses is preserved in perforin-deficient mice and released by depletion of CD4+CD25+ regulatory T cells

Third-generation anti-CD19 chimeric antigen receptor T-cells incorporating a TLR2 domain for relapsed or refractory B-cell lymphoma: a phase I clinical trial protocol (ENABLE)

Three cases of disputed paternity in dogs resolved by the use of DNA fingerprinting

Tumor immunotherapy by epicutaneous immunization requires langerhans cells.

Tumor-peptide-pulsed dendritic cells isolated from spleen or cultured in vitro from bone marrow precursors can provide protection against tumor challenge.

Using magnetic resonance imaging to evaluate dendritic cell-based vaccination

Utilizing the adjuvant properties of CD1d-dependent NK T cells in T cell-mediated immunotherapy

Vaccination with irradiated tumor cells pulsed with an adjuvant that stimulates NKT cells is an effective treatment for glioma.