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List of works by Brett Nixon

65. Localisation of tyrosine phosphorylated proteins on mouse spermatozoa during zona pellucida interaction and characterisation of sperm surface phosphoproteins

A Kinase Anchor Protein 4 Is Vulnerable to Oxidative Adduction in Male Germ Cells

scientific article published on 20 December 2019

A model protocol for the cryopreservation and recovery of motile lizard sperm using the phosphodiesterase inhibitor caffeine

scientific article published on 22 June 2020

A novel approach to nonsurgical sterilization; application of menadione-modified gonocyte-targeting M13 bacteriophage for germ cell ablation in utero

scientific article published on 01 October 2020

A novel germ cell protein, SPIF (sperm PKA interacting factor), is essential for the formation of a PKA/TCP11 complex that undergoes conformational and phosphorylation changes upon capacitation

scientific journal article

A scRNA-seq Approach to Identifying Changes in Spermatogonial Stem Cell Gene Expression Following <i>in vitro</i> Culture

publication published on 01 April 2022

A unique combination of male germ cell miRNAs coordinates gonocyte differentiation

scientific article

Adding insult to injury: effects of xenobiotic-induced preantral ovotoxicity on ovarian development and oocyte fusibility

scientific article published on 9 September 2010

Analysis of Epididymal Protein Synthesis and Secretion

scientific article published on 25 August 2018

Analysis of chaperone proteins associated with human spermatozoa during capacitation

scientific article published on 26 June 2007

Analysis of the effects of polyphenols on human spermatozoa reveals unexpected impacts on mitochondrial membrane potential, oxidative stress and DNA integrity; implications for assisted reproductive technology

scientific article published on 19 September 2016

Analysis of the small non-protein-coding RNA profile of mouse spermatozoa reveals specific enrichment of piRNAs within mature spermatozoa.

scientific article

Are sperm capacitation and apoptosis the opposite ends of a continuum driven by oxidative stress?

scientific article published in 2015

Assessment of microRNA expression in mouse epididymal epithelial cells and spermatozoa by next generation sequencing.

scientific article

Autophagy in Female Fertility: A Role in Oxidative Stress and Aging

scientific article published on 01 March 2020

Biochemical alterations in the oocyte in support of early embryonic development.

scientific article published on 7 September 2016

Capacitation in the presence of methyl-β-cyclodextrin results in enhanced zona pellucida-binding ability of stallion spermatozoa

scientific article published on 20 December 2013

Cellular mechanisms regulating sperm-zona pellucida interaction

scientific article

Characterisation of mouse epididymosomes reveals a complex profile of microRNAs and a potential mechanism for modification of the sperm epigenome.

scientific article published on 23 August 2016

Characteristics of the Epididymal Luminal Environment Responsible for Sperm Maturation and Storage.

scientific article published on 28 February 2018

Characterization of a novel role for the dynamin mechanoenzymes in the regulation of human sperm acrosomal exocytosis

scientific article published in October 2017

Chronic Acrylamide Exposure in Male Mice Results in Elevated DNA Damage in the Germline and Heritable Induction of CYP2E1 in the Testes.

scientific article published on 31 August 2016

Chronic acrylamide exposure in male mice induces DNA damage to spermatozoa; Potential for amelioration by resveratrol

scientific article published on 9 May 2016

Chronic exposure to acrylamide induces DNA damage in male germ cells of mice

Composition and significance of detergent resistant membranes in mouse spermatozoa.

scientific article published in January 2009

Cryopreservation of saltwater crocodile (Crocodylus porosus) spermatozoa

scientific article published on 01 October 2017

DNA damage and repair in the female germline: contributions to ART

scientific article published on 01 March 2019

DNA damage in human spermatozoa is highly correlated with the efficiency of chromatin remodeling and the formation of 8-hydroxy-2'-deoxyguanosine, a marker of oxidative stress.

scientific article published on 3 June 2009

Data on the concentrations of etoposide, PSC833, BAPTA-AM, and cycloheximide that do not compromise the vitality of mature mouse oocytes, parthenogencially activated and fertilized embryos

scientific article

Development of a novel electrophoretic system for the isolation of human spermatozoa

scientific article published on 14 April 2005

Developmental expression of the dynamin family of mechanoenzymes in the mouse epididymis

scientific article

Differential cell death decisions in the testis: evidence for an exclusive window of ferroptosis in round spermatids

scientific article published on 01 May 2019

Double Strand Break DNA Repair occurs via Non-Homologous End-Joining in Mouse MII Oocytes.

scientific article published on 26 June 2018

Dynamin 2 is essential for mammalian spermatogenesis.

scientific article published on 11 October 2016

Dynamin 2-dependent endocytosis is essential for mouse oocyte development and fertility

scientific article published on 17 February 2020

Dynamin regulates specific membrane fusion events necessary for acrosomal exocytosis in mouse spermatozoa.

scientific article

Electrophilic aldehyde products of lipid peroxidation selectively adduct to heat shock protein 90 and arylsulfatase A in stallion spermatozoa.

scientific article

Elucidation of the signaling pathways that underpin capacitation-associated surface phosphotyrosine expression in mouse spermatozoa

scientific article published in July 2010

Epididymal CYP2E1 plays a critical role in acrylamide-induced DNA damage in spermatozoa and paternally mediated embryonic resorptions†.

scientific article

Evidence for the involvement of PECAM-1 in a receptor mediated signal-transduction pathway regulating capacitation-associated tyrosine phosphorylation in human spermatozoa.

scientific article

Examination of the immunocontraceptive potential of recombinant rabbit fertilin subunits in rabbit.

scientific article published in October 1997

First recorded pregnancy and normal birth after ICSI using electrophoretically isolated spermatozoa.

scientific article

Formation and Dissociation of Sperm Bundles in Monotremes

scientific article published on 24 August 2016

GLIPR1L1 is an IZUMO-binding protein required for optimal fertilization in the mouse

scientific article published on 31 October 2019

Genome analysis of the platypus reveals unique signatures of evolution

scientific article

Genome analysis of the platypus reveals unique signatures of evolution

scientific article published in Nature

Glioma pathogenesis-related 1-like 1 is testis enriched, dynamically modified, and redistributed during male germ cell maturation and has a potential role in sperm-oocyte binding

scientific journal article

Glycogen synthase kinase 3 regulates acrosomal exocytosis in mouse spermatozoa via dynamin phosphorylation.

scientific article published on 25 March 2015

Heat Shock Protein A2 (HSPA2): Regulatory Roles in Germ Cell Development and Sperm Function.

scientific article

Heat Shock Protein member A2 forms a stable complex with angiotensin converting enzyme and protein disulfide isomerase A6 in human spermatozoa

scientific article published on 16 December 2015

Heat exposure induces oxidative stress and DNA damage in the male germ line

scientific article published on 17 January 2018

High Resolution Proteomic Analysis of Subcellular Fractionated Boar Spermatozoa Provides Comprehensive Insights Into Perinuclear Theca-Residing Proteins

scientific article published on 18 February 2022

Identification of RARhoGAP, a novel putative RhoGAP gene expressed in male germ cells

scientific journal article

Identification of a key role for permeability glycoprotein in enhancing the cellular defense mechanisms of fertilized oocytes.

scientific article

Identification of the molecular chaperone, heat shock protein 1 (chaperonin 10), in the reproductive tract and in capacitating spermatozoa in the male mouse

scientific article

Impact of estrogenic compounds on DNA integrity in human spermatozoa: evidence for cross-linking and redox cycling activities

scientific article

Improved methods of DNA extraction from human spermatozoa that mitigate experimentally-induced oxidative DNA damage.

scientific article published on 26 March 2018

Inhibition of arachidonate 15-lipoxygenase prevents 4-hydroxynonenal-induced protein damage in male germ cells.

scientific article

Investigation into the presence and functional significance of proinsulin C-peptide in the female germline†

scientific article published on 01 May 2019

Investigation of the expression and functional significance of the novel mouse sperm protein, a disintegrin and metalloprotease with thrombospondin type 1 motifs number 10 (ADAMTS10).

scientific article published on 28 March 2012

Investigation of the mechanisms by which the molecular chaperone HSPA2 regulates the expression of sperm surface receptors involved in human sperm-oocyte recognition.

scientific article published on 17 December 2012

Investigation of the role of SRC in capacitation-associated tyrosine phosphorylation of human spermatozoa.

scientific article

Involvement of multimeric protein complexes in mediating the capacitation-dependent binding of human spermatozoa to homologous zonae pellucidae

scientific article published on 13 June 2011

Jumping the gun: smoking constituent BaP causes premature primordial follicle activation and impairs oocyte fusibility through oxidative stress.

scientific article published on 8 February 2012

Limitations to intergenerational inheritance: subchronic paternal stress preconception does not influence offspring anxiety

scientific article published on 29 September 2020

Localization and significance of molecular chaperones, heat shock protein 1, and tumor rejection antigen gp96 in the male reproductive tract and during capacitation and acrosome reaction

scientific article published on 29 September 2004

Male Infertility: Shining a Light on Lipids and Lipid-Modulating Enzymes in the Male Germline

scientific article published on 23 January 2020

Mass spectrometry reveals distinct proteomic profiles in high- and low-quality stallion spermatozoa

scientific article published on 01 August 2020

Mechanisms of tethering and cargo transfer during epididymosome-sperm interactions

scientific article published on 18 April 2019

Mechanistic Insight into the Regulation of Lipoxygenase-Driven Lipid Peroxidation Events in Human Spermatozoa and Their Impact on Male Fertility

scientific article published on 31 December 2020

Melatonin prevents postovulatory oocyte aging in the mouse and extends the window for optimal fertilization in vitro.

scientific article published on 21 March 2013

Modification of Crocodile Spermatozoa Refutes the Tenet That Post-testicular Sperm Maturation Is Restricted To Mammals

scientific article published on 02 August 2018

Molecular Mechanisms Responsible for Increased Vulnerability of the Ageing Oocyte to Oxidative Damage.

scientific article published on 18 October 2017

Molecular and functional characterization of the rabbit epididymal secretory protein 52, REP52

scientific article published on 16 January 2008

Molecular insights into the divergence and diversity of post-testicular maturation strategies

scientific article published on 09 August 2020

Monotremes provide a key to understanding the evolutionary significance of epididymal sperm maturation.

scientific article published on 25 March 2011

Mouse quiescin sulfhydryl oxidases exhibit distinct epididymal luminal distribution with segment-specific sperm surface associations

scientific article published on 01 November 2018

Mouse spermatocytes express CYP2E1 and respond to acrylamide exposure

scientific article (publication date: 2014)

New insights into sperm physiology and pathology.

scientific article published on January 2010

New insights into the molecular mechanisms of sperm-egg interaction.

scientific article published on July 2007

New proteins identified in epididymal fluid from the platypus (Ornithorhynchus anatinus)

scientific article published on 01 January 2009

Next Generation Sequencing Analysis Reveals Segmental Patterns of microRNA Expression in Mouse Epididymal Epithelial Cells.

scientific article published on 13 August 2015

Non-coding RNA in Spermatogenesis and Epididymal Maturation

scientific article

Non-surgical sterilisation methods may offer a sustainable solution to feral horse (Equus caballus) overpopulation

scientific article

Novel characterization of the HSPA2-stabilizing protein BAG6 in human spermatozoa

scientific article

Oxidative Stress Dysregulates Protein Homeostasis Within the Male Germ Line

scientific article published on 01 March 2020

Oxidative Stress in the Male Germline: A Review of Novel Strategies to Reduce 4-Hydroxynonenal Production

article

Oxidative damage in naturally aged mouse oocytes is exacerbated by dysregulation of proteasomal activity

scientific article published in Journal of Biological Chemistry

Paternal impacts on development: identification of genomic regions vulnerable to oxidative DNA damage in human spermatozoa

scientific article published on 01 October 2019

Pharmacological inhibition of arachidonate 15-lipoxygenase (ALOX15) protects human spermatozoa against oxidative stress.

scientific article published on 13 March 2018

Platelet activating factor receptor acts to limit colitis-induced liver inflammation

scientific article published on 15 April 2020

Polarized epithelium-sperm co-culture system reveals stimulatory factors for the secretion of mouse epididymal quiescin sulfhydryl oxidase 1

scientific article published on 26 February 2022

Post-testicular sperm maturation and identification of an epididymal protein in the Japanese quail (Coturnix coturnix japonica)

scientific article published on 25 January 2014

Probing the Origins of 1,800 MHz Radio Frequency Electromagnetic Radiation Induced Damage in Mouse Immortalized Germ Cells and Spermatozoa

scholarly article by Brendan J Houston et al published 2018 in Frontiers in Public Health

Profiling of epididymal small non-protein-coding RNAs

scientific article published on 25 April 2019

Proteolytic degradation of heat shock protein A2 occurs in response to oxidative stress in male germ cells of the mouse

scientific article published on 08 December 2016

Proteomic and functional analysis of human sperm detergent resistant membranes.

scientific article published in October 2011

Proteomic changes in mammalian spermatozoa during epididymal maturation

scientific article published on July 2007

Proteomic insights into the maturation and capacitation of mammalian spermatozoa.

scientific article published on August 2012

Proteomic profiling of mouse epididymosomes reveals their contributions to post-testicular sperm maturation

scientific article published on 13 September 2018

Quantitative phosphoproteomics uncovers synergy between DNA-PK and FLT3 inhibitors in acute myeloid leukaemia

scientific article published on 16 October 2020

Rabbit epididymal secretory proteins. I. Characterization and hormonal regulation.

scientific article

Rabbit epididymal secretory proteins. II. Immunolocalization and sperm association of REP38

scientific article published on 01 July 2002

Rabbit epididymal secretory proteins. III. Molecular cloning and characterization of the complementary DNA for REP38.

scholarly article

Role of the epididymis in sperm competition

scientific article published on July 2007

Roles of male reproductive tract extracellular vesicles in reproduction

scientific article published on 03 September 2020

Shwachman-Bodian-Diamond syndrome (SBDS) protein is a direct inhibitor of protein phosphatase 2A (PP2A) activity and overexpressed in acute myeloid leukaemia

scientific article published on 08 April 2020

Signal Transduction in Diffuse Intrinsic Pontine Glioma

scientific article published on 14 August 2019

Sperm capacitation: a distant landscape glimpsed but unexplored.

scientific article published on 26 September 2013

Sperm-zona pellucida interaction: molecular mechanisms and the potential for contraceptive intervention.

scientific article published on January 2010

Staying alive: PI3K pathway promotes primordial follicle activation and survival in response to 3MC-induced ovotoxicity.

scientific article published on 12 April 2012

Suppressor of cytokine signaling 4 (SOCS4): moderator of ovarian primordial follicle activation

scientific article published on March 2012

Testicular descent, sperm maturation and capacitation. Lessons from our most distant relatives, the monotremes

scientific article published on January 2009

The 12 (th) International Symposium on Spermatology

scientific article published on July 2015

The Australian saltwater crocodile (Crocodylus porosus) provides evidence that the capacitation of spermatozoa may extend beyond the mammalian lineage.

scientific article published in May 2016

The Composition and Significance of Lipid Rafts in Mouse Spermatozoa

article

The Impact of Aging on Macroautophagy in the Pre-ovulatory Mouse Oocyte

scientific article published on 29 June 2021

The Sins of Our Forefathers: Paternal Impacts on De Novo Mutation Rate and Development

scientific article published on 14 July 2020

The biological significance of detergent-resistant membranes in spermatozoa.

scientific article published on 25 October 2009

The chaperonin containing TCP1 complex (CCT/TRiC) is involved in mediating sperm-oocyte interaction

scientific journal article

The chemokine CXCL12 and its receptor CXCR4 are implicated in human seminoma metastasis

scientific article published on 15 March 2013

The contribution of epididymosomes to the sperm small RNA profile

scientific article published on 01 June 2019

The effects of radiofrequency electromagnetic radiation on sperm function

scientific article

The electrophoretic separation of spermatozoa: an analysis of genotype, surface carbohydrate composition and potential for capacitation

scientific article published on 12 May 2011

The function of chaperone proteins in the assemblage of protein complexes involved in gamete adhesion and fusion processes.

scientific article published on 24 January 2013

The identification of mouse sperm-surface-associated proteins and characterization of their ability to act as decapacitation factors.

scientific article

The impact of oxidative stress on chaperone-mediated human sperm-egg interaction.

scientific article published on 7 September 2015

The lipid peroxidation product 4-hydroxynonenal contributes to oxidative stress-mediated deterioration of the ageing oocyte

scientific article

The microRNA signature of mouse spermatozoa is substantially modified during epididymal maturation.

scientific article published on 2 September 2015

The molecular chaperone HSPA2 plays a key role in regulating the expression of sperm surface receptors that mediate sperm-egg recognition

scientific article

The rise of testicular germ cell tumours: the search for causes, risk factors and novel therapeutic targets

The rise of testicular germ cell tumours: the search for causes, risk factors and novel therapeutic targets.

scientific article published on 19 February 2013

The role of molecular chaperones in mouse sperm-egg interactions

scientific article

The role of molecular chaperones in spermatogenesis and the post-testicular maturation of mammalian spermatozoa

scientific article published on 20 April 2012

The role of the molecular chaperone heat shock protein A2 (HSPA2) in regulating human sperm-egg recognition

scientific article

The small non-coding RNA profile of mouse oocytes is modified during aging

scientific article published on 01 May 2019

Transcriptomic analysis of the seminal vesicle response to the reproductive toxicant acrylamide

scientific article published on 08 October 2021

Transgenerational inheritance: how impacts to the epigenetic and genetic information of parents affect offspring health

scientific article published on 01 September 2019

Tyrosine phosphorylation activates surface chaperones facilitating sperm-zona recognition

scientific journal article

Understanding the Villain: DMBA-induced preantral ovotoxicity involves selective follicular destruction and primordial follicle activation through PI3K/Akt and mTOR signaling.

scientific article published on 23 July 2011

Whole-body exposures to radiofrequency-electromagnetic energy can cause DNA damage in mouse spermatozoa via an oxidative mechanism ⬇️

scientific article published on 25 November 2019

miRNA and mammalian male germ cells

scientific article

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