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List of works by Jean Claude Alvarez

A LC/MS/MS micro-method for human plasma quantification of vemurafenib. Application to treated melanoma patients

scientific article published on 18 April 2014

A high-performance liquid chromatography method with photodiode-array UV detection for therapeutic drug monitoring of the nontricyclic antidepressant drugs.

scientific article published in October 2003

A high-resolution ICP-MS method for the determination of 38 inorganic elements in human whole blood, urine, hair and tissues after microwave digestion

scientific article published on 20 February 2019

A novel LC-ESI-MS-MS method for sensitive quantification of colchicine in human plasma: application to two case reports

scientific article published on 01 April 2006

A practical tranexamic acid dosing scheme based on population pharmacokinetics in children undergoing cardiac surgery.

scientific article published on April 2013

A rapid and sensitive high-performance liquid chromatography method for determination of embutramide (a Tanax or T61 component) in human blood with photodiode-array UV detection.

scientific article published in March 2004

A validated assay for the quantitative analysis of tranexamic acid in human serum by liquid chromatography coupled with electrospray ionization mass spectrometry.

scientific article published on 11 January 2010

Acenocoumarol sensitivity and pharmacokinetic characterization of CYP2C9 *5/*8,*8/*11,*9/*11 and VKORC1*2 in black African healthy Beninese subjects.

scientific article

Amoxicillin/clavulanic acid-warfarin drug interaction: a randomized controlled trial.

scientific article

An Automated Method for the Determination of Trimebutine and N-Mono-Desmethyl Trimebutine by On-Line Turbulent Flow Coupled with Liquid Chromatography-Tandem Mass Spectrometry in Human Plasma: Application to a Fatal Poisoning Case with Toxicokinetic

scientific article published on 4 September 2015

An automated method for measurement of methoxetamine in human plasma by use of turbulent flow on-line extraction coupled with liquid chromatography and mass spectrometric detection.

scientific article published on 19 October 2012

An epidemic of dystonic reactions in central Africa.

scientific article published in February 2017

Anti-colchicine Fab fragments prevent lethal colchicine toxicity in a porcine model: a pharmacokinetic and clinical study

scientific article published on 15 January 2018

Anticraving Effect of Baclofen in Alcohol-Dependent Patients.

scientific article published on 24 July 2015

CSF 5-HIAA levels are lower in impulsive as compared to nonimpulsive violent suicide attempters and control subjects

scientific article published on 01 June 1999

Cannabinoids inhibit cholinergic contraction in human airways through prejunctional CB1 receptors.

scientific article

Clinical and neurochemical effect of acute tryptophan depletion in unaffected relatives of patients with bipolar affective disorder.

scientific article published in August 2001

Clinical, histological, and biochemical predictors of postsurgical neuropathic pain

scientific article published in November 2015

Commentary on: Thogmartin JR, Wilson CI, Palma NA, Ignacio SS, Shuman MJ, Flannagan LM. Sickle cell trait-associated deaths: a case series with a review of the literature. J Forensic Sci 2011;56(5):1352-60

scientific article published on 01 March 2012

Common Neurotransmission Recruited in (R,S)-Ketamine and (2R,6R)-Hydroxynorketamine-Induced Sustained Antidepressant-like Effects.

scientific article

Conflicting hair testing results can have an impact in courts: interpretation of single exposure to zolpidem

scientific article published on 11 March 2014

Critical care testing: SFBC recommendations in 2018.

scientific article published in January 2018

Detection and quantification of 12 anabolic steroids and analogs in human whole blood and 20 in hair using LC-HRMS/MS: application to real cases.

scientific article published on 24 February 2017

Determination of fluoxetine and its metabolite norfluoxetine in serum and brain areas using high-performance liquid chromatography with ultraviolet detection ⬇️

scientific article published on April 10, 1998

Development and validation of a liquid chromatography-tandem mass spectrometry method for simultaneous detection of 10 illicit drugs in oral fluid collected with FLOQSwabs™ and application to real samples

scientific article published on 17 January 2019

Development of a sensitive untargeted LC-HRMS screening devoted to hair analysis through a shared MS2 spectra database: a step towards early detection of new psychoactive substances

scientific article published on 25 November 2018

Diagnosis of adrenal insufficiency in severe sepsis and septic shock

scientific article published on 14 September 2006

Differential changes in brain and platelet 5-HT concentrations after steady-state achievement and repeated administration of antidepressant drugs in mice

scientific article published on 01 December 1999

Discriminating factors in fatal blunt trauma from low level falls and homicide

scientific article published on 10 March 2015

Does the Administration of Sevelamer or Nicotinamide Modify Uremic Toxins or Endotoxemia in Chronic Hemodialysis Patients?

scientific article published on 01 June 2019

Drug stability testing to support clinical feasibility investigations for intrathecal baclofen-clonidine admixture.

scientific article published in September 2004

Drug use and driving

scientific article published on 5 May 2015

Drug-facilitated sexual assault (DFSA) involving 4-methylethcathinone (4-MEC), 3,4-Methylenedioxypyrovalerone (MDPV), and doxylamine highlighted by hair analysis.

scientific article

Effect of Smoked Cannabis on Vigilance and Accident Risk Using Simulated Driving in Occasional and Chronic Users and the Pharmacokinetic-Pharmacodynamic Relationship

scientific article published on 14 March 2019

Factitious increases in serum testosterone concentrations related to phenylbutazone therapy.

scientific article

Fibrinogen Poissy II (gammaN361K): a novel dysfibrinogenemia associated with defective polymerization and peptide B release

scientific article published on 01 April 2003

Fibrinogen Saint-Germain I: a case of the heterozygous Aalpha GLY 12 --> VAL fibrinogen variant

scientific article published on 01 March 2002

Glyphosate and aminomethylphosphonic acid in human hair quantified by an LC‐MS/MS method

scientific article published on 02 May 2022

Hair analysis does not allow to discriminate between acute and chronic administrations of a drug in young children.

scientific article

High variability in the exposure of baclofen in alcohol-dependent patients

scientific article

Human plasma quantification of droperidol and ondansetron used in preventing postoperative nausea and vomiting with a LC/ESI/MS/MS method

scientific article published on 16 December 2010

Human plasma quantification of fludrocortisone using liquid chromatography coupled with atmospheric pressure chemical ionization mass spectrometry after low-dosage administration.

scientific article

Identification and quantification of 4-methylethcathinone (4-MEC) and 3,4-methylenedioxypyrovalerone (MDPV) in hair by LC-MS/MS after chronic administration.

scientific article published on 24 November 2016

Interaction between acetaminophen and warfarin in adults receiving long-term oral anticoagulants: a randomized controlled trial

scientific article published on 30 December 2010

LC-MS/MS determination of tranexamic acid in human plasma after phospholipid clean-up

scientific article published on 19 April 2017

LC-MS/MS method for quantification of baclofen in hair: A useful tool to assess compliance in alcohol dependent patients?

scientific article published on 2 October 2017

LC-MS/MS quantification of free and Fab-bound colchicine in plasma, urine and organs following colchicine administration and colchicine-specific Fab fragments treatment in Göttingen minipigs

scientific article published on 20 June 2017

Liquid chromatography/photodiode array detection for determination of strychnine in blood: a fatal case report.

scientific article

Low blood cholesterol and low platelet serotonin levels in violent suicide attempters

scientific article published on 01 April 1999

Low serum cholesterol in violent but not in non-violent suicide attempters.

scientific article published in August 2000

Measurement of atropine and scopolamine in hair by LC–MS/MS after Datura stramonium chronic exposure ⬇️

scientific article published on October 22, 2012

Mid-morning tryptophan depletion delays REM sleep onset in healthy subjects.

scientific article published in November 2002

Molecular adsorbent recirculating system (MARS) and continuous veno-venous hemodiafiltration (CVVHDF) for diltiazem removal: An in vitro study

scientific article published on 01 December 2020

Non-response to consecutive antidepressant therapy caused by CYP2D6 ultrarapid metabolizer phenotype.

scientific article

Passive cocaine inhalation by a 25-month-old child ⬇️

scientific article published on April 19, 2013

Pharmacokinetics of oral fludrocortisone in septic shock.

scientific article

Pharmacological data of a successful 4-days-a-week regimen in HIV antiretroviral therapy (ANRS 162-4D trial)

scientific article published on 03 October 2020

Plasma and Intracellular Antiretroviral Concentrations in HIV-Infected Patients under Short Cycles of Antiretroviral Therapy.

scientific article published on 9 November 2014

Plasma serotonin level after 1 day of fluoxetine treatment: a biological predictor for antidepressant response?

scientific article published on 01 March 1999

Poisoning associated with inappropriate use of a eutectic mixture of lidocaine and prilocaine before laser-assisted hair removal: about 3 cases

scientific article published on 21 May 2018

Population Pharmacokinetic-Pharmacodynamic Model of Oral Fludrocortisone and Intravenous Hydrocortisone in Healthy Volunteers

scientific article published on 12 January 2017

Population pharmacokinetic model of blood THC and its metabolites in chronic and occasional cannabis users and relationship with on-site oral fluid testing

scientific article published on 02 January 2021

Population pharmacokinetics of lopinavir/ritonavir in Covid-19 patients

scientific article published on 13 October 2020

Population pharmacokinetics of methadone hydrochloride after a single intramuscular administration in adult Japanese sika deer (Cervus nippon nippon).

scientific article

Population pharmacokinetics of tranexamic acid in adults undergoing cardiac surgery with cardiopulmonary bypass.

scientific article published on 23 July 2013

Preoperative Evaluation of the Renal Function before the Treatment of Abdominal Aortic Aneurysms.

scientific article published on 24 November 2016

Prevalence and surveillance of synthetic cathinones use by hair analysis: an update review.

scientific article

Prevalence of New Psychoactive Substances (NPS) and conventional drugs of abuse (DOA) in high risk populations from Paris (France) and its suburbs: A cross sectional study by hair testing (2012-2017)

scientific article published on 30 August 2019

Proceedings of Réanimation 2017, the French Intensive Care Society International Congress

scientific article

Proceedings of Réanimation 2017, the French Intensive Care Society International Congress

scientific article published on 10 January 2017

Quantification of remifentanil and propofol in human plasma: a LC-MS/MS assay validated according to the EMA guideline.

scientific article

Rectal wall hemorrhage in hanging autopsy cases

scientific article published on 26 February 2012

Reply to the letter to the Editor "Prediction of lopinavir/ritonavir effectiveness in COVID-19 patients: a recall of basic pharmacology concepts"

scientific article published on 26 November 2020

Sensitive quantification of apomorphine in human plasma using a LC-ESI-MS-MS method

scientific article published on 01 June 2006

Study of the diagnostic value of iron in fresh water drowning

scientific article published on 08 November 2005

Sudden death associated to vascular Ehlers-Danlos syndrome. A case report.

scientific article published on 26 January 2011

Suicidal and criminal immolations: an 18-year study and review of the literature.

scientific article published on 30 December 2010

Survival time estimation using Injury Severity Score (ISS) in homicide cases.

scientific article

Synthetic cannabinoid isomers characterization by MALDI-MS imaging: Application to single scalp hair

scientific article published on 19 September 2018

Tenofovir pharmacokinetic after sleeve-gastrectomy in four severely obese patients living with HIV.

scientific article published on 24 June 2016

The BRAF Inhibitor Vemurafenib Enhances UV-Induced Skin Carcinogenesis in Beta HPV38 E6 and E7 Transgenic Mice.

scientific article

The expression and relaxant effect of bitter taste receptors in human bronchi.

scientific article

The measured glomerular filtration rate (mGFR) before and 6 months after bariatric surgery: A pilot study.

scientific article

Undetermined Manner of Death: An Autopsy Series

scientific article published on 03 August 2015

Unusual death by rubber bullet: should these guns be reclassified as lethal weapons?

scientific article published on 01 March 2012

Vemurafenib Use in an Infant for High-Risk Langerhans Cell Histiocytosis.

scientific article

[A fatal laryngeal lesion]

scientific article published on 18 May 2011

[EEG contribution to the diagnosis of baclofen overdose]

scientific article published on 01 March 2006

[SFBC guidelines on critical care testing]

scientific article published on 01 March 2016

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