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List of works by Aaron Ring

"Velcro" engineering of high affinity CD47 ectodomain as signal regulatory protein α (SIRPα) antagonists that enhance antibody-dependent cellular phagocytosis

scientific article published on 2 April 2015

68. Active Monitoring of a Healthcare Worker Cohort During the COVID-19 Epidemic

scientific article

A Forward Chemical Genetic Screen Reveals Gut Microbiota Metabolites That Modulate Host Physiology

scientific article published on 18 April 2019

A human secretome library screen reveals a role for Peptidoglycan Recognition Protein 1 in Lyme borreliosis

scientific article published on 11 November 2020

Abstract S03-03: Cancer patients display diminished viral RNA clearance and altered T cell responses during SARS-CoV-2 infection

scholarly article

Activation and allosteric modulation of a muscarinic acetylcholine receptor

scientific article

Adrenaline-activated structure of β2-adrenoceptor stabilized by an engineered nanobody

scientific article

An Ixodes scapularis protein disulfide isomerase contributes to Borrelia burgdorferi colonization of the vector

scientific article published on 14 September 2020

Angiotensin II signaling increases activity of the renal Na-Cl cotransporter through a WNK4-SPAK-dependent pathway

scientific article

Antibodies to Interleukin-2 Elicit Selective T Cell Subset Potentiation through Distinct Conformational Mechanisms.

scientific article published on May 2015

CD47-blocking immunotherapies stimulate macrophage-mediated destruction of small-cell lung cancer

scientific article published on 13 June 2016

CD47-blocking therapies stimulate macrophage cytokine secretion and are effective in a model of peritoneal carcinomatosis

scientific article

Cytokine therapy reverses NK cell anergy in MHC-deficient tumors

scientific article

Decoupling the Functional Pleiotropy of Stem Cell Factor by Tuning c-Kit Signaling

scientific article published in March 2017

Diverse Functional Autoantibodies in Patients with COVID-19

scientific article published on 12 December 2020

Engineered SIRPα variants as immunotherapeutic adjuvants to anticancer antibodies

scientific article

Eradication of Canine Diffuse Large B-Cell Lymphoma in a Murine Xenograft Model with CD47 Blockade and Anti-CD20.

scientific article

GDF15 Is an Inflammation-Induced Central Mediator of Tissue Tolerance

scientific article published on 08 August 2019

IL-18BP is a secreted immune checkpoint and barrier to IL-18 immunotherapy

scientific article published on 24 June 2020

Immune responses to SARS-CoV-2 infection in hospitalized pediatric and adult patients

scientific article published on 21 September 2020

Immunologically distinct responses occur in the CNS of COVID-19 patients

scientific article published on 12 September 2020

Improving macrophage responses to therapeutic antibodies by molecular engineering of SIRPα variants

scientific article published on 29 July 2013

Interleukin-2 activity can be fine tuned with engineered receptor signaling clamps.

scientific article

Kinetics of antibody responses dictate COVID-19 outcome

scientific article published on 22 December 2020

Mechanistic and structural insight into the functional dichotomy between IL-2 and IL-15

scientific article

Molecular physiology of the WNK kinases.

scientific article

Mouse Model of SARS-CoV-2 Reveals Inflammatory Role of Type I Interferon Signaling

scientific article published on 16 June 2020

Mouse model of SARS-CoV-2 reveals inflammatory role of type I interferon signaling

scientific article published on 27 May 2020

Mouse model of SARS-CoV-2 reveals inflammatory role of type I interferon signaling

scientific article published on 1 December 2020

Neuroinvasion of SARS-CoV-2 in human and mouse brain

scientific article published on 8 September 2020

Neuroinvasion of SARS-CoV-2 in human and mouse brain

scientific article

PD-1 expression by tumour-associated macrophages inhibits phagocytosis and tumour immunity.

scientific article

Practical Immuno-PET Radiotracer Design Considerations for Human Immune Checkpoint Imaging.

scientific article published on 15 December 2016

Regulatory T cells control NK cells in an insulitic lesion by depriving them of IL-2.

scientific article

SARS-CoV-2 Infection of the Placenta

scientific article published on 5 May 2020

Sex differences in immune responses that underlie COVID-19 disease outcomes

scientific article published on 26 August 2020

Sex differences in immune responses to SARS-CoV-2 that underlie disease outcomes

scientific article published on 9 June 2020

Structure and Dynamics of PD-L1 and an Ultra-High-Affinity PD-1 Receptor Mutant

scientific article published on 7 September 2016

T cells expressing chimeric antigen receptor promote immune tolerance.

scientific article published on 19 October 2017

The intestinal parasite <i>Cryptosporidium</i> is controlled by an enterocyte intrinsic inflammasome that depends on NLRP6

scientific article published on 01 January 2021

WNK protein kinases modulate cellular Cl- flux by altering the phosphorylation state of the Na-K-Cl and K-Cl cotransporters

scientific article published on October 2006

WNK4 regulates activity of the epithelial Na+ channel in vitro and in vivo.

scholarly article

Yeast surface display platform for rapid discovery of conformationally selective nanobodies.

scientific article published on 12 February 2018

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