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List of works by Naoki Mochizuki

15-lipoxygenase-1 in the vasculature: expanding roles in angiogenesis

scientific article published in February 2008

A Method for Multiple Mycotoxin Analysis in Wines by Solid Phase Extraction and Multifunctional Cartridge Purification, and Ultra-High-Performance Liquid Chromatography Coupled to Tandem Mass Spectrometry ⬇️

scientific article published on June 15, 2012

A New Secretory Peptide of Natriuretic Peptide Family, Osteocrin, Suppresses the Progression of Congestive Heart Failure After Myocardial Infarction

scientific article published on 11 January 2018

A cardiac myosin light chain kinase regulates sarcomere assembly in the vertebrate heart

scientific article

A method for simultaneous determination of 20 Fusarium toxins in cereals by high-resolution liquid chromatography-Orbitrap mass spectrometry with a pentafluorophenyl column

scientific article published on 14 May 2015

A molecular atlas of cell types and zonation in the brain vasculature

scientific article published on 14 February 2018

A novel LIM protein Cal promotes cardiac differentiation by association with CSX/NKX2-5

scientific article

A novel actin bundling/filopodium-forming domain conserved in insulin receptor tyrosine kinase substrate p53 and missing in metastasis protein

scientific article

A novel dynamin-associating molecule, formin-binding protein 17, induces tubular membrane invaginations and participates in endocytosis

scientific article

AKAP12 regulates vascular integrity in zebrafish ⬇️

scientific article published on March 31, 2012

AMIGO2, a novel membrane anchor of PDK1, controls cell survival and angiogenesis via Akt activation.

scientific article

AMPK controls the speed of microtubule polymerization and directional cell migration through CLIP-170 phosphorylation

scientific article published on 23 May 2010

Activation of rac and cdc42 video imaged by fluorescent resonance energy transfer-based single-molecule probes in the membrane of living cells

scientific article

Activity of Rho-family GTPases during cell division as visualized with FRET-based probes

scientific article

Adaptor molecule Crk is required for sustained phosphorylation of Grb2-associated binder 1 and hepatocyte growth factor-induced cell motility of human synovial sarcoma cell lines

scientific article published in July 2006

Adaptor protein Crk is required for ephrin-B1-induced membrane ruffling and focal complex assembly of human aortic endothelial cells.

scientific article

Akt-PDK1 complex mediates epidermal growth factor-induced membrane protrusion through Ral activation

scientific article

An Evolutionarily Conserved Role for Polydom/Svep1 During Lymphatic Vessel Formation

scientific article

An interaction between glucagon-like peptide-1 and adenosine contributes to cardioprotection of a dipeptidyl peptidase 4 inhibitor from myocardial ischemia-reperfusion injury.

scientific article published on 6 March 2015

Angiopoietin-1 guides directional angiogenesis through integrin αvβ5 signaling for recovery of ischemic retinopathy.

scientific article published in September 2013

Angiopoietin-1 induces Kruppel-like factor 2 expression through a phosphoinositide 3-kinase/AKT-dependent activation of myocyte enhancer factor 2.

scientific article

Angiopoietin-1/Tie2 Signal Augments Basal Notch Signal Controlling Vascular Quiescence by Inducing Delta-Like 4 Expression through AKT-mediated Activation of β-Catenin ⬇️

scientific article published on January 6, 2011

Angiopoietin-1/Tie2 receptor signaling in vascular quiescence and angiogenesis

scientific article published on March 2010

Angiopoietin-like protein 2 promotes chronic adipose tissue inflammation and obesity-related systemic insulin resistance

scientific article

Angiotensin II type 1 receptor blocker prevents atrial structural remodeling in rats with hypertension induced by chronic nitric oxide inhibition

scientific article published on 01 April 2006

Arf6 regulates tumour angiogenesis and growth through HGF-induced endothelial β1 integrin recycling

scientific article published on 4 August 2015

Arhgef15 promotes retinal angiogenesis by mediating VEGF-induced Cdc42 activation and potentiating RhoJ inactivation in endothelial cells

scientific article

Atrial natriuretic peptide prevents cancer metastasis through vascular endothelial cells

scientific article

Author Correction: A molecular atlas of cell types and zonation in the brain vasculature

scientific article published in Nature

Autonomy and Non-autonomy of Angiogenic Cell Movements Revealed by Experiment-Driven Mathematical Modeling

scientific article published on 19 November 2015

Beyond proof of concepts for ideal cardiac regenerative therapy

scientific article published on 17 May 2017

Biomechanical signaling within the developing zebrafish heart attunes endocardial growth to myocardial chamber dimensions

scientific article published on 11 September 2019

Calpain Protects the Heart from Hemodynamic Stress ⬇️

scientific article published on July 27, 2011

Carbohydrate-binding protein CLEC14A regulates VEGFR-2- and VEGFR-3-dependent signals during angiogenesis and lymphangiogenesis

scientific article published on 19 December 2016

Cardiac forces regulate zebrafish heart valve delamination by modulating Nfat signaling

scientific article published on 14 January 2022

Cardiac ischemia activates vascular endothelial cadherin promoter in both preexisting vascular cells and bone marrow cells involved in neovascularization

scientific article published on 16 March 2006

Cardiomyokines from the heart

scientific article published on 13 December 2017

Cdc42 mediates Bmp-induced sprouting angiogenesis through Fmnl3-driven assembly of endothelial filopodia in zebrafish.

scientific article published in January 2015

Cell type-specific regulation of RhoA activity during cytokinesis.

scientific article published on 12 August 2004

Characterization of fumonisin A-series by high-resolution liquid chromatography-orbitrap mass spectrometry

scientific article published on 21 August 2014

Circulating osteocrin stimulates bone growth by limiting C-type natriuretic peptide clearance

scientific article published on 9 October 2017

Clarification of mural cell coverage of vascular endothelial cells by live imaging of zebrafish.

scientific article published on 7 March 2016

Conformational switch of angiotensin II type 1 receptor underlying mechanical stress-induced activation

scientific article

Crucial roles of PECAM-1 in shear stress sensing of vascular endothelial cells

scientific article published in November 2004

Cyclic AMP potentiates vascular endothelial cadherin-mediated cell-cell contact to enhance endothelial barrier function through an Epac-Rap1 signaling pathway

scientific article

Cytochalasin D enhances the accumulation of a protease‐resistant form of prion protein in ScN2a cells: involvement of PI3 kinase/Akt signalling pathway ⬇️

scientific article published on January 1, 2012

Degradation of aflatoxin B1 during the fermentation of alcoholic beverages

scientific article published on 28 June 2013

Differential function of Tie2 at cell-cell contacts and cell-substratum contacts regulated by angiopoietin-1

scientific article

Dipeptidyl-peptidase IV inhibition improves pathophysiology of heart failure and increases survival rate in pressure-overloaded mice ⬇️

scientific article published on March 15, 2013

Docking protein Gab1 is an essential component of postnatal angiogenesis after ischemia via HGF/c-met signaling.

scientific article

Does the pathophysiology of heart failure prime the incidence of cancer?

scientific article published on 6 April 2017

ERK is an anti-inflammatory signal that suppresses expression of NF-kappaB-dependent inflammatory genes by inhibiting IKK activity in endothelial cells

scientific article

Early stages of energy transduction by myosin: roles of Arg in switch I, of Glu in switch II, and of the salt-bridge between them

scientific article

Endoderm-derived islet1-expressing cells differentiate into endothelial cells to function as the vascular HSPC niche in zebrafish

scientific article published in 2023

Endophilin BAR domain drives membrane curvature by two newly identified structure-based mechanisms

scientific article

Endothelial Ca 2+ oscillations reflect VEGFR signaling-regulated angiogenic capacity in vivo.

scientific article

Endothelial Gab1 deletion accelerates angiotensin II-dependent vascular inflammation and atherosclerosis in apolipoprotein E knockout mice

scientific article published on 19 May 2012

Enhanced functional gap junction neoformation by protein kinase A-dependent and Epac-dependent signals downstream of cAMP in cardiac myocytes

scientific article published on 25 August 2005

EphA2 engages Git1 to suppress Arf6 activity modulating epithelial cell-cell contacts

scientific article

EphA4-mediated Rho activation via Vsm-RhoGEF expressed specifically in vascular smooth muscle cells

scientific article

EphrinA/EphA signal facilitates insulin-like growth factor-I–induced myogenic differentiation through suppression of the Ras/extracellular signal–regulated kinase 1/2 cascade in myoblast cell lines ⬇️

scientific article published on July 27, 2011

EphrinA1-EphA2 Signal Induces Compaction and Polarization of Madin-Darby Canine Kidney Cells by Inactivating Ezrin through Negative Regulation of RhoA ⬇️

scientific article published on October 6, 2011

Excitotoxic targeting of Kidins220 to the Golgi apparatus precedes calpain cleavage of Rap1-activation complexes

scientific article published on 11 July 2019

Flow pattern-dependent endothelial cell responses through transcriptional regulation

scientific article published on 18 August 2017

Flow-Dependent Endothelial YAP Regulation Contributes to Vessel Maintenance.

scientific article published on March 2017

G protein-coupled APJ receptor signaling induces focal adhesion formation and cell motility.

scientific article published on November 2005

Gab family proteins are essential for postnatal maintenance of cardiac function via neuregulin-1/ErbB signaling

scientific article published in July 2007

Granulocyte colony-stimulating factor mediates cardioprotection against ischemia/reperfusion injury via phosphatidylinositol-3-kinase/Akt pathway in canine hearts

scientific article published on 01 June 2006

Guidelines for morpholino use in zebrafish.

scientific article

H2 Mediates Cardioprotection Via Involvements of KATP Channels and Permeability Transition Pores of Mitochondria in Dogs ⬇️

scientific article published on 01 June 2012

High-endothelial cell-derived S1P regulates dendritic cell localization and vascular integrity in the lymph node

scientific article published on 01 October 2019

Hippo signaling determines the number of venous pole cells that originate from the anterior lateral plate mesoderm in zebrafish.

scientific article

Identification and characterization of zipper-interacting protein kinase as the unique vascular smooth muscle myosin phosphatase-associated kinase

scientific article

Identification and quantification of fumonisin A1, A2, and A3 in corn by high-resolution liquid chromatography-orbitrap mass spectrometry

scientific article published on 16 February 2015

Identification of Fer tyrosine kinase localized on microtubules as a platelet endothelial cell adhesion molecule-1 phosphorylating kinase in vascular endothelial cells

scientific article

Identification of genes related to heart failure using global gene expression profiling of human failing myocardium

article

Identification of the Mtus1 Splice Variant as a Novel Inhibitory Factor Against Cardiac Hypertrophy

scientific article published on 06 July 2016

In vivo analysis of cardiomyocyte proliferation during trabeculation

scientific article published on 30 July 2018

Increased endoplasmic reticulum stress in atherosclerotic plaques associated with acute coronary syndrome

scientific article published on 20 August 2007

Increases in intracellular sodium activate transcription and gene expression via the salt-inducible kinase 1 network in an atrial myocyte cell line

scientific article

Interaction of FoxO1 and TSC2 induces insulin resistance through activation of the mammalian target of rapamycin/p70 S6K pathway

scientific article

Interaction of scaffolding adaptor protein Gab1 with tyrosine phosphatase SHP2 negatively regulates IGF-I-dependent myogenic differentiation via the ERK1/2 signaling pathway

scientific article published on 23 June 2008

In Vivo Visualization of Cardiomyocyte Apicobasal Polarity Reveals Epithelial to Mesenchymal-like Transition during Cardiac Trabeculation.

scientific article published in December 2016

Lack of salt-inducible kinase 2 (SIK2) prevents the development of cardiac hypertrophy in response to chronic high-salt intake.

scientific article

Live imaging of angiogenesis during cutaneous wound healing in adult zebrafish

scientific article published on 04 January 2019

Local activation of Rap1 contributes to directional vascular endothelial cell migration accompanied by extension of microtubules on which RAPL, a Rap1-associating molecule, localizes

scientific article

Long-term and sustained COMP-Ang1 induces long-lasting vascular enlargement and enhanced blood flow

scientific article published on 16 June 2005

Long-term stimulation of adenosine A2b receptors begun after myocardial infarction prevents cardiac remodeling in rats

scientific article published on 16 October 2006

Looking back and moving forward: recent advances in understanding of cardiovascular development by imaging of zebrafish

scientific article published on 10 April 2015

Lymphocytes mobilization into blood regulated by Spns2, a sphingosine 1-phosphate transporter, expressed on endothelial cells

scientific article published on April 1, 2013

Lysophosphatidic Acid Receptor 4 Activation Augments Drug Delivery in Tumors by Tightening Endothelial Cell-Cell Contact

scientific article published in August 2017

MAGI-1 is required for Rap1 activation upon cell-cell contact and for enhancement of vascular endothelial cadherin-mediated cell adhesion

scientific article

MAGI1 as a link between endothelial activation and ER stress drives atherosclerosis

scientific article published on 04 April 2019

Marcksl1 modulates endothelial cell mechanoresponse to haemodynamic forces to control blood vessel shape and size

scientific article published on 30 October 2020

Metabolism of Zearalenone in the Course of Beer Fermentation ⬇️

scientific article published on February 14, 2011

Metformin prevents progression of heart failure in dogs: role of AMP-activated protein kinase.

scientific article published on 4 May 2009

Minimization of carryover for high-throughput liquid chromatography with tandem mass spectrometry analysis of 14 mycotoxins in corn grits

scientific article published on 07 May 2014

Mural lymphatic endothelial cells regulate meningeal angiogenesis in the zebrafish.

scientific article published on May 2017

Myocardium-derived angiopoietin-1 is essential for coronary vein formation in the developing heart

scientific article

Neuronal sFlt1 and Vegfaa determine venous sprouting and spinal cord vascularization.

scientific article published on 10 January 2017

Non-linear Equation using Plasma Brain Natriuretic Peptide Levels to Predict Cardiovascular Outcomes in Patients with Heart Failure

scientific article

On the myosin catalysis of ATP hydrolysis

scientific article

Osteocrin, a peptide secreted from the heart and other tissues, contributes to cranial osteogenesis and chondrogenesis in zebrafish

scientific article published on 19 December 2016

PRMT8 as a phospholipase regulates Purkinje cell dendritic arborization and motor coordination

scientific article

PSF1, a DNA replication factor expressed widely in stem and progenitor cells, drives tumorigenic and metastatic properties

scientific article

Peri-arterial specification of vascular mural cells from naïve mesenchyme requires Notch signaling

scientific article published on 25 January 2019

Polydom Is an Extracellular Matrix Protein Involved in Lymphatic Vessel Remodeling

scientific article published on 8 February 2017

Prolonged targeting of ischemic/reperfused myocardium by liposomal adenosine augments cardioprotection in rats

scientific article published in February 2009

Protein Kinase A (PKA) Type I Interacts with P-Rex1, a Rac Guanine Nucleotide Exchange Factor: EFFECT ON PKA LOCALIZATION AND P-Rex1 SIGNALING

scientific article published on 21 January 2016

Protocol for whole-mount X-gal staining combined with tissue clearing in embryo and adult mouse using CUBIC

scientific article published on 20 January 2022

R-Ras regulates exocytosis by Rgl2/Rlf-mediated activation of RalA on endosomes.

scientific article

Rap1 potentiates endothelial cell junctions by spatially controlling myosin II activity and actin organization

scientific article published on 09 September 2013

Rap1b Promotes Notch-Signal-Mediated Hematopoietic Stem Cell Development by Enhancing Integrin-Mediated Cell Adhesion

scientific article published on 18 April 2019

Receptor activator of nuclear factor (NF)-kappaB ligand (RANKL) increases vascular permeability: impaired permeability and angiogenesis in eNOS-deficient mice

scientific article published on 12 October 2006

Regulation of aldosterone and cortisol production by the transcriptional repressor neuron restrictive silencer factor

scientific article

Regulatory roles for APJ, a seven-transmembrane receptor related to angiotensin-type 1 receptor in blood pressure in vivo

scientific article

RhoA and ROCK mediate histamine-induced vascular leakage and anaphylactic shock.

scientific article

RhoJ integrates attractive and repulsive cues in directional migration of endothelial cells

scientific article published on 29 April 2020

S1P-S1p2 Signaling in Cardiac Precursor Cells Migration

S1P-Yap1 signaling regulates endoderm formation required for cardiac precursor cell migration in zebrafish

scientific article published in October 2014

SHP2 mediates gp130-dependent cardiomyocyte hypertrophy via negative regulation of skeletal alpha-actin gene

scientific article published on 11 March 2010

SWAP-70 is a guanine-nucleotide-exchange factor that mediates signalling of membrane ruffling

scientific article published on April 2002

Salt-inducible kinase 1 regulates E-cadherin expression and intercellular junction stability

scientific article

Selective inhibition of vascular endothelial growth factor receptor-2 (VEGFR-2) identifies a central role for VEGFR-2 in human aortic endothelial cell responses to VEGF.

scientific article published on January 2003

Simultaneous determination of sweeteners in beverages by LC-MS/MS.

scientific article

Simultaneous determination of water-soluble vitamins in beverages and dietary supplements by LC-MS/MS.

scientific article published on 17 November 2014

Single-cell RNA sequencing of mouse brain and lung vascular and vessel-associated cell types

scientific article published on 21 August 2018

Spatial and temporal role of the apelin/APJ system in the caliber size regulation of blood vessels during angiogenesis

scientific article

Sphingosine 1-phosphate (S1P) regulates vascular contraction via S1P3 receptor: investigation based on a new S1P3 receptor antagonist

scientific article published on 22 January 2010

Sphingosine 1-phosphate induces membrane ruffling and increases motility of human umbilical vein endothelial cells via vascular endothelial growth factor receptor and CrkII

scientific article (publication date: 28 June 2002)

The E1784K mutation in SCN5A is associated with mixed clinical phenotype of type 3 long QT syndrome

scientific article published on June 2008

The parallel growth of motoneuron axons with the dorsal aorta depends on Vegfc/Vegfr3 signaling in zebrafish

scientific article

The secreted protein ANGPTL2 promotes metastasis of osteosarcoma cells through integrin α5β1, p38 MAPK, and matrix metalloproteinases.

scientific article published on 21 January 2014

The sphingolipid transporter spns2 functions in migration of zebrafish myocardial precursors

scientific article

The sphingosine-1-phosphate transporter Spns2 expressed on endothelial cells regulates lymphocyte trafficking in mice

scientific journal article

Tie2 is tied at the cell-cell contacts and to extracellular matrix by angiopoietin-1

scientific article published on March 2009

Tip cell-specific requirement for an atypical Gpr124- and Reck-dependent Wnt/β-catenin pathway during brain angiogenesis

scientific article published on 8 June 2015

Transmission of force and displacement within the myosin molecule

scientific article published in November 2004

Tumor cell-derived angiopoietin-like protein ANGPTL2 is a critical driver of metastasis.

scientific article

Use of serum fibroblast growth factor 23 vs. plasma B-type natriuretic peptide levels in assessing the pathophysiology of patients with heart failure

scientific article published on 29 September 2016

Valves Are a Conserved Feature of the Zebrafish Lymphatic System

scientific article published on 26 September 2019

Vascular endothelial adrenomedullin-RAMP2 system is essential for vascular integrity and organ homeostasis

scientific article published on 25 January 2013

Vascular endothelial cadherin-mediated cell-cell adhesion regulated by a small GTPase, Rap1.

scientific article

Vascular endothelial-cadherin stabilizes at cell-cell junctions by anchoring to circumferential actin bundles through alpha- and beta-catenins in cyclic AMP-Epac-Rap1 signal-activated endothelial cells

scientific article

Visualizing the cell-cycle progression of endothelial cells in zebrafish

scientific article published on 26 June 2014

Yap1 promotes sprouting and proliferation of lymphatic progenitors downstream of Vegfc in the zebrafish trunk

scientific article published on 30 April 2019

Zyxin mediates actin fiber reorganization in epithelial-mesenchymal transition and contributes to endocardial morphogenesis

scientific article

[Dynamics of Rho-family G proteins as visualized with FRET-based probes]

scientific article published on 01 August 2005

[Nano -level imaging for analyzing protein structure and function].

scientific article

[Vascular stabilization by angiopoietin-1.].

scientific article

β-Catenin-dependent transcription is central to Bmp-mediated formation of venous vessels.

scientific article published on 6 January 2015

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