List of works - Manuela Rodriquez

A serum nuclear magnetic resonance-based metabolomic signature of antiphospholipid syndrome.

scientific article published on 2 November 2016

Benzodiazepine Scaffold as Drug-like Molecular Simplification of FR235222: A Chemical Tool for Exploring HDAC Inhibition

scientific article published on 24 August 2016

Chemistry and biology of chromatin remodeling agents: state of art and future perspectives of HDAC inhibitors.

scientific article

Colorimetric tools for solid-phase organic synthesis.

scientific article published in September 2004

Design and Synthesis of Cyclopeptide Analogues of the Potent Histone Deacetylase Inhibitor FR235222

scientific article published on 01 October 2007

Effects of FR235222, a novel HDAC inhibitor, in proliferation and apoptosis of human leukaemia cell lines: role of annexin A1.

scientific article

Facile Baeyer–Villiger oxidation of cyclic ketones: conventional versus microwave-assisted approach

article

Fast determination of underivatized gentamicin C components and impurities by LC-MS using a porous graphitic carbon stationary phase.

scientific article

Histone deacetylase inhibitors in the treatment of cancer: overview and perspectives.

scientific article published on July 2012

Histone deacetylase inhibitors in the treatment of hematological malignancies.

scientific article published on June 2011

Investigating the Neuroprotective Effects of Turmeric Extract: Structural Interactions of β-Amyloid Peptide with Single Curcuminoids.

scientific article published on 22 December 2016

Ionic liquid as a suitable phase for multistep parallel synthesis of an array of isoxazolines

scientific article published on 01 October 2003

Is it time to integrate sex and gender into drug design and development?

scientific article published in January 2015

N-thioalkylcarbazoles derivatives as new anti-proliferative agents: synthesis, characterisation and molecular mechanism evaluation. ⬇️

scientific article published in December 2018

Oxime amides as a novel zinc binding group in histone deacetylase inhibitors: synthesis, biological activity, and computational evaluation.

scientific article

Saliva of patients affected by salivary gland tumour: An NMR metabolomics analysis

scientific article published on 09 August 2018

Solid-phase synthesis of conformationally constrained peptidomimetics based on a 3,6-disubstituted-1,4-diazepan-2,5-dione core.

scientific article published in October 2003

Specific targeting highly conserved residues in the HIV-1 reverse transcriptase primer grip region. Design, synthesis, and biological evaluation of novel, potent, and broad spectrum NNRTIs with antiviral activity

scientific article published in November 2005

Synthesis and biological evaluation of Santacruzamate-A based analogues

scientific article

The isoprenoid derivative N6 -benzyladenosine CM223 exerts antitumor effects in glioma patient-derived primary cells through the mevalonate pathway.

scientific article published on 18 April 2017

Total synthesis and biological evaluation of halipeptins A and D and analogues

scientific article published on April 2006

Total synthesis and structural elucidation of azaspiracid-1. Construction of key building blocks for originally proposed structure

scientific article published on 01 February 2006

Total synthesis, NMR solution structure, and binding model of the potent histone deacetylase inhibitor FR235222

scientific article published on 01 January 2006

β-Amyloid-acetylcholine molecular interaction: new role of cholinergic mediators in anti-Alzheimer therapy?

scientific article published on 12 July 2016

List of works by Manuela Rodriquez

A serum nuclear magnetic resonance-based metabolomic signature of antiphospholipid syndrome.

Benzodiazepine Scaffold as Drug-like Molecular Simplification of FR235222: A Chemical Tool for Exploring HDAC Inhibition

Chemistry and biology of chromatin remodeling agents: state of art and future perspectives of HDAC inhibitors.

Colorimetric tools for solid-phase organic synthesis.

Design and Synthesis of Cyclopeptide Analogues of the Potent Histone Deacetylase Inhibitor FR235222

Effects of FR235222, a novel HDAC inhibitor, in proliferation and apoptosis of human leukaemia cell lines: role of annexin A1.

Facile Baeyer–Villiger oxidation of cyclic ketones: conventional versus microwave-assisted approach

Fast determination of underivatized gentamicin C components and impurities by LC-MS using a porous graphitic carbon stationary phase.

Histone deacetylase inhibitors in the treatment of cancer: overview and perspectives.

Histone deacetylase inhibitors in the treatment of hematological malignancies.

Investigating the Neuroprotective Effects of Turmeric Extract: Structural Interactions of β-Amyloid Peptide with Single Curcuminoids.

Ionic liquid as a suitable phase for multistep parallel synthesis of an array of isoxazolines

Is it time to integrate sex and gender into drug design and development?

N-thioalkylcarbazoles derivatives as new anti-proliferative agents: synthesis, characterisation and molecular mechanism evaluation. ⬇️

Oxime amides as a novel zinc binding group in histone deacetylase inhibitors: synthesis, biological activity, and computational evaluation.

Saliva of patients affected by salivary gland tumour: An NMR metabolomics analysis

Solid-phase synthesis of conformationally constrained peptidomimetics based on a 3,6-disubstituted-1,4-diazepan-2,5-dione core.

Specific targeting highly conserved residues in the HIV-1 reverse transcriptase primer grip region. Design, synthesis, and biological evaluation of novel, potent, and broad spectrum NNRTIs with antiviral activity

Synthesis and biological evaluation of Santacruzamate-A based analogues

The isoprenoid derivative N6 -benzyladenosine CM223 exerts antitumor effects in glioma patient-derived primary cells through the mevalonate pathway.

Total synthesis and biological evaluation of halipeptins A and D and analogues

Total synthesis and structural elucidation of azaspiracid-1. Construction of key building blocks for originally proposed structure

Total synthesis, NMR solution structure, and binding model of the potent histone deacetylase inhibitor FR235222

β-Amyloid-acetylcholine molecular interaction: new role of cholinergic mediators in anti-Alzheimer therapy?