List of works - Sophie E. Jackson

19F NMR studies of the native and denatured states of green fluorescent protein

scientific article published in August 2006

1H, 15N and 13C backbone assignment of the green fluorescent protein (GFP)

scientific article published on 01 July 2003

A comparison of the folding of two knotted proteins: YbeA and YibK.

scientific article

A high-throughput fluorescence chemical denaturation assay as a general screen for protein-ligand binding

scientific article published on 05 December 2010

A pH-Induced Switch in Human Glucagon-like Peptide-1 Aggregation Kinetics

scientific article

A recurring theme in protein engineering: the design, stability and folding of repeat proteins.

scientific article

All-in-one disulfide bridging enables the generation of antibody conjugates with modular cargo loading

An independent method for the analysis of protein folding kinetics from all-atom molecular dynamics simulations

scientific article published on 01 August 2005

Backbone 1H, 13C and 15N assignments of YibK and avariant containing a unique cysteine residue at C-terminus in 8 M urea-denatured states [corrected].

scientific article published on 14 July 2013

Backbone NMR assignments of a topologically knotted protein in urea-denatured state

scientific article published on 3 July 2013

Backbone assignments of the 26 kDa neuron-specific ubiquitin carboxyl-terminal hydrolase L1 (UCH-L1).

scientific article

Bayesian inference of accurate population sizes and FRET efficiencies from single diffusing biomolecules

scientific article published on 18 August 2014

Biochemical and structural studies of the interaction of Cdc37 with Hsp90.

scientific article published in July 2004

Chaperome screening leads to identification of Grp94/Gp96 and FKBP4/52 as modulators of the α-synuclein-elicited immune response

scientific article published on 6 October 2015

Characterising the Folding Pathways of Topologically Knotted Proteins

Characterization of the Folding of a 52-Knotted Protein Using Engineered Single-Tryptophan Variants

scientific article published in December 2016

Comparative analysis of the folding dynamics and kinetics of an engineered knotted protein and its variants derived from HP0242 of Helicobacter pylori

scientific article published on 20 August 2015

Conformational dynamics of the molecular chaperone Hsp90 in complexes with a co-chaperone and anticancer drugs

scientific article

Destabilised mutants of ubiquitin gain equal stability in crowded solutions

scientific article published on 30 March 2007

Distinct Mechanisms of Calmodulin Binding and Regulation of Adenylyl Cyclases 1 and 8 ⬇️

scientific article published on September 21, 2012

Effect of cavity-creating mutations in the hydrophobic core of chymotrypsin inhibitor 2

scientific article

Energetic and structural analysis of the role of tryptophan 59 in FKBP12

scientific article (publication date: 4 March 2003)

Erratum to: Backbone 1H, 13C and 15N assignments of YibK and a variant containing a unique cysteine residue at C-terminus in 8 M urea-denatured states

scholarly article published in Biomolecular NMR Assignments

Evidence of an intermediate and parallel pathways in protein unfolding from single-molecule fluorescence.

scientific article

Experimental detection of knotted conformations in denatured proteins

scientific article

Exploring knotting mechanisms in protein folding.

scholarly article

Exploring sequence/folding space: folding studies on multiple hydrophobic core mutants of ubiquitin.

scientific article

Factors affecting the physical stability (aggregation) of peptide therapeutics

scientific article

Faculty Opinions recommendation of Multiple conformations of E. coli Hsp90 in solution: insights into the conformational dynamics of Hsp90

Fast folding of a four-helical bundle protein

scientific article published in August 2002

Folding and stability of the ligand-binding domain of the glucocorticoid receptor

scientific article

Folding of chymotrypsin inhibitor 2. 1. Evidence for a two-state transition

scientific article

Folding studies on a knotted protein

scientific article published on 28 January 2005

Folding study of Venus reveals a strong ion dependence of its yellow fluorescence under mildly acidic conditions

scientific article

Heterogeneity and dynamics in the assembly of the heat shock protein 90 chaperone complexes

scientific article published on 19 October 2011

How do small single-domain proteins fold? ⬇️

scientific article published on January 1, 1998

How to fold intricately: using theory and experiments to unravel the properties of knotted proteins

How to fold intricately: using theory and experiments to unravel the properties of knotted proteins.

scientific article published on 26 October 2016

Hsp70 forms antiparallel dimers stabilized by post-translational modifications to position clients for transfer to Hsp90.

scientific article published on 23 April 2015

Hsp70 inhibits the nucleation and elongation of tau and sequesters tau aggregates with high affinity

scientific article published on 4 January 2018

Hsp90 inhibits α-synuclein aggregation by interacting with soluble oligomers.

scientific article published on 13 August 2013

Hsp90 reaches new heights. Conference on the Hsp90 chaperone machine

scientific article published in February 2003

Hsp90: Structure and Function ⬇️

scientific article published on January 1, 2013

Hsp90: from structure to phenotype

scientific article published on 01 December 2004

Independent ATPase activity of Hsp90 subunits creates a flexible assembly platform

scientific article published in November 2004

Is an intermediate state populated on the folding pathway of ubiquitin?

scientific article

Knot formation in newly translated proteins is spontaneous and accelerated by chaperonins

scientific article published on 18 December 2011

Knots in soft condensed matter

scientific article published on 20 August 2015

Knotted fusion proteins reveal unexpected possibilities in protein folding

scientific article published in June 2008

Knotting and unknotting of a protein in single molecule experiments.

scientific article published on 23 June 2016

Local and long-range stability in tandemly arrayed tetratricopeptide repeats

scientific article

Low-temperature study of the plastocyanin–ferricyanide electron-transfer reaction in aqueous methanol reveals an unusual energy barrier

Mechanistic insights into the folding of knotted proteins in vitro and in vivo

scientific article

Molecular knots in biology and chemistry

scientific article published on 20 August 2015

Native-state dynamics of the ubiquitin family: implications for function and evolution

scientific article published in March 2005

Probing nature's knots: the folding pathway of a knotted homodimeric protein

scientific article

Protein denaturation and protein:drugs interactions from intrinsic protein fluorescence measurements at the nanolitre scale

scientific article

Protein folding: defining a "standard" set of experimental conditions and a preliminary kinetic data set of two-state proteins

scientific article

Spin relaxation effects in photochemically induced dynamic nuclear polarization spectroscopy of nuclei with strongly anisotropic hyperfine couplings

scientific article published on 30 June 2007

Stable intermediate states and high energy barriers in the unfolding of GFP.

scientific article

Stimulation of the weak ATPase activity of human hsp90 by a client protein

scientific article

Structures and folding pathways of topologically knotted proteins

scientific article published on 10 December 2010

The AAA+ protease ClpXP can easily degrade a 3 and a 5-knotted protein

The Amyloid Fibril-Forming β-Sheet Regions of Amyloid β and α-Synuclein Preferentially Interact with the Molecular Chaperone 14-3-3ζ

The Effect of Parkinson's-Disease-Associated Mutations on the Deubiquitinating Enzyme UCH-L1

article

The Knotted Protein UCH-L1 Exhibits Partially Unfolded Forms under Native Conditions that Share Common Structural Features with Its Kinetic Folding Intermediates

scientific article published on 8 April 2016

The co-chaperone p23 arrests the Hsp90 ATPase cycle to trap client proteins

scientific article published on 15 December 2005

The dimerization of an alpha/beta-knotted protein is essential for structure and function

scientific article published on January 2007

The discovery and development of the green fluorescent protein, GFP.

scientific article published on 3 September 2009

The extremely slow-exchanging core and acid-denatured state of green fluorescent protein

scientific article

The folding and design of repeat proteins: reaching a consensus

scientific article

The folding pathway of ubiquitin from all-atom molecular dynamics simulations

scientific article

The folding, stability and conformational dynamics of beta-barrel fluorescent proteins

scientific article

The solution to multiple structures

scientific article published in May 2008

Toward Rapid Aspartic Acid Isomer Localization in Therapeutic Peptides Using Cyclic Ion Mobility Mass Spectrometry

scientific article published in 2022

Ubiquitin chain conformation regulates recognition and activity of interacting proteins

scientific article

Ubiquitin folds through a highly polarized transition state

scientific article published on 27 April 2005

Ubiquitin: A Small Protein Folding Paradigm

Ubiquitin: a small protein folding paradigm.

scientific article

Understanding the folding of GFP using biophysical techniques.

scientific article published on October 2006

Untangling the folding mechanism of the 5(2)-knotted protein UCH-L3.

scientific article published on 24 March 2009

Use of protein engineering techniques to elucidate protein folding pathways

scientific article published on January 2008

List of works by Sophie E. Jackson

19F NMR studies of the native and denatured states of green fluorescent protein

1H, 15N and 13C backbone assignment of the green fluorescent protein (GFP)

A comparison of the folding of two knotted proteins: YbeA and YibK.

A high-throughput fluorescence chemical denaturation assay as a general screen for protein-ligand binding

A pH-Induced Switch in Human Glucagon-like Peptide-1 Aggregation Kinetics

A recurring theme in protein engineering: the design, stability and folding of repeat proteins.

All-in-one disulfide bridging enables the generation of antibody conjugates with modular cargo loading

An independent method for the analysis of protein folding kinetics from all-atom molecular dynamics simulations

Backbone 1H, 13C and 15N assignments of YibK and avariant containing a unique cysteine residue at C-terminus in 8 M urea-denatured states [corrected].

Backbone NMR assignments of a topologically knotted protein in urea-denatured state

Backbone assignments of the 26 kDa neuron-specific ubiquitin carboxyl-terminal hydrolase L1 (UCH-L1).

Bayesian inference of accurate population sizes and FRET efficiencies from single diffusing biomolecules

Biochemical and structural studies of the interaction of Cdc37 with Hsp90.

Chaperome screening leads to identification of Grp94/Gp96 and FKBP4/52 as modulators of the α-synuclein-elicited immune response

Characterising the Folding Pathways of Topologically Knotted Proteins

Characterization of the Folding of a 52-Knotted Protein Using Engineered Single-Tryptophan Variants

Comparative analysis of the folding dynamics and kinetics of an engineered knotted protein and its variants derived from HP0242 of Helicobacter pylori

Conformational dynamics of the molecular chaperone Hsp90 in complexes with a co-chaperone and anticancer drugs

Destabilised mutants of ubiquitin gain equal stability in crowded solutions

Distinct Mechanisms of Calmodulin Binding and Regulation of Adenylyl Cyclases 1 and 8 ⬇️

Effect of cavity-creating mutations in the hydrophobic core of chymotrypsin inhibitor 2

Energetic and structural analysis of the role of tryptophan 59 in FKBP12

Erratum to: Backbone 1H, 13C and 15N assignments of YibK and a variant containing a unique cysteine residue at C-terminus in 8 M urea-denatured states

Evidence of an intermediate and parallel pathways in protein unfolding from single-molecule fluorescence.

Experimental detection of knotted conformations in denatured proteins

Exploring knotting mechanisms in protein folding.

Exploring sequence/folding space: folding studies on multiple hydrophobic core mutants of ubiquitin.

Factors affecting the physical stability (aggregation) of peptide therapeutics

Faculty Opinions recommendation of Multiple conformations of E. coli Hsp90 in solution: insights into the conformational dynamics of Hsp90

Fast folding of a four-helical bundle protein

Folding and stability of the ligand-binding domain of the glucocorticoid receptor

Folding of chymotrypsin inhibitor 2. 1. Evidence for a two-state transition

Folding studies on a knotted protein

Folding study of Venus reveals a strong ion dependence of its yellow fluorescence under mildly acidic conditions

Heterogeneity and dynamics in the assembly of the heat shock protein 90 chaperone complexes

How do small single-domain proteins fold? ⬇️

How to fold intricately: using theory and experiments to unravel the properties of knotted proteins

How to fold intricately: using theory and experiments to unravel the properties of knotted proteins.

Hsp70 forms antiparallel dimers stabilized by post-translational modifications to position clients for transfer to Hsp90.

Hsp70 inhibits the nucleation and elongation of tau and sequesters tau aggregates with high affinity

Hsp90 inhibits α-synuclein aggregation by interacting with soluble oligomers.

Hsp90 reaches new heights. Conference on the Hsp90 chaperone machine

Hsp90: Structure and Function ⬇️

Hsp90: from structure to phenotype

Independent ATPase activity of Hsp90 subunits creates a flexible assembly platform

Is an intermediate state populated on the folding pathway of ubiquitin?

Knot formation in newly translated proteins is spontaneous and accelerated by chaperonins

Knots in soft condensed matter

Knotted fusion proteins reveal unexpected possibilities in protein folding

Knotting and unknotting of a protein in single molecule experiments.

Local and long-range stability in tandemly arrayed tetratricopeptide repeats

Low-temperature study of the plastocyanin–ferricyanide electron-transfer reaction in aqueous methanol reveals an unusual energy barrier

Mechanistic insights into the folding of knotted proteins in vitro and in vivo

Molecular knots in biology and chemistry

Native-state dynamics of the ubiquitin family: implications for function and evolution

Probing nature's knots: the folding pathway of a knotted homodimeric protein

Protein denaturation and protein:drugs interactions from intrinsic protein fluorescence measurements at the nanolitre scale

Protein folding: defining a "standard" set of experimental conditions and a preliminary kinetic data set of two-state proteins

Spin relaxation effects in photochemically induced dynamic nuclear polarization spectroscopy of nuclei with strongly anisotropic hyperfine couplings

Stable intermediate states and high energy barriers in the unfolding of GFP.

Stimulation of the weak ATPase activity of human hsp90 by a client protein

Structures and folding pathways of topologically knotted proteins

The AAA+ protease ClpXP can easily degrade a 3 and a 5-knotted protein

The Amyloid Fibril-Forming β-Sheet Regions of Amyloid β and α-Synuclein Preferentially Interact with the Molecular Chaperone 14-3-3ζ

The Effect of Parkinson's-Disease-Associated Mutations on the Deubiquitinating Enzyme UCH-L1

The Knotted Protein UCH-L1 Exhibits Partially Unfolded Forms under Native Conditions that Share Common Structural Features with Its Kinetic Folding Intermediates

The co-chaperone p23 arrests the Hsp90 ATPase cycle to trap client proteins

The dimerization of an alpha/beta-knotted protein is essential for structure and function

The discovery and development of the green fluorescent protein, GFP.

The extremely slow-exchanging core and acid-denatured state of green fluorescent protein

The folding and design of repeat proteins: reaching a consensus

The folding pathway of ubiquitin from all-atom molecular dynamics simulations

The folding, stability and conformational dynamics of beta-barrel fluorescent proteins

The solution to multiple structures

Toward Rapid Aspartic Acid Isomer Localization in Therapeutic Peptides Using Cyclic Ion Mobility Mass Spectrometry

Ubiquitin chain conformation regulates recognition and activity of interacting proteins

Ubiquitin folds through a highly polarized transition state

Ubiquitin: A Small Protein Folding Paradigm

Ubiquitin: a small protein folding paradigm.