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List of works by James Ellis

"Agouti NOD": identification of a CBA-derived Idd locus on Chromosome 7 and its use for chimera production with NOD embryonic stem cells

scientific article published on 29 October 2005

A chemical probe selectively inhibits G9a and GLP methyltransferase activity in cells

scientific article

A rapid screening procedure for the identification of high-titer retrovirus packaging clones.

scientific article

A vertebrate Polycomb response element governs segmentation of the posterior hindbrain

scientific article

Alternative induced pluripotent stem cell characterization criteria for in vitro applications

scientific article published on 01 March 2009

Alternative polyadenylation is a determinant of oncogenic Ras function

scientific article published on 17 December 2021

Ataxia-telangiectasia mutated (ATM) deficiency decreases reprogramming efficiency and leads to genomic instability in iPS cells

scientific article published on 6 March 2011

Benefits of Utilizing Gene-Modified iPSCs for Clinical Applications

scientific article published on 01 October 2010

Cartilage tissue engineering identifies abnormal human induced pluripotent stem cells

scientific article published on January 2013

Coding regions affect mRNA stability in human cells

scientific article published on 16 September 2019

Complete Disruption of Autism-Susceptibility Genes by Gene Editing Predominantly Reduces Functional Connectivity of Isogenic Human Neurons

article

Constitutive heterochromatin reorganization during somatic cell reprogramming

scientific article

Correction of Sickle Cell Disease in Transgenic Mouse Models by Gene Therapy ⬇️

scientific article published on December 14, 2001

Deviation of islet autoreactivity to cryptic epitopes protects NOD mice from diabetes

scientific article published on 01 February 2003

Directed differentiation of human pluripotent stem cells into mature airway epithelia expressing functional CFTR protein

scientific article published on September 2012

EOS lentiviral vector selection system for human induced pluripotent stem cells

scientific article published in January 2009

Evaluation of beta-globin gene therapy constructs in single copy transgenic mice.

scientific article

Fyn Kinase regulates GluN2B subunit-dominant NMDA receptors in human induced pluripotent stem cell-derived neurons

scientific article published on 4 April 2016

High-level erythroid-specific gene expression in primary human and murine hematopoietic cells with self-inactivating lentiviral vectors

scientific article published in November 2001

Human induced pluripotent stem cell derived neurons as a model for Williams-Beuren syndrome

scientific article published on 24 November 2015

Human induced pluripotent stem cell-derived lung progenitor and alveolar epithelial cells attenuate hyperoxia-induced lung injury

scientific article published on 20 October 2017

Identification of TIA1 mRNA targets during human neuronal development

scientific article published on 19 August 2021

Induced pluripotent stem cells and reprogramming: seeing the science through the hype

scientific article published on 27 October 2009

Initiation of DNA replication at the human beta-globin 3' enhancer

scientific article

Isolation of MECP2-null Rett Syndrome patient hiPS cells and isogenic controls through X-chromosome inactivation

scientific article

Isolation of human iPS cells using EOS lentiviral vectors to select for pluripotency

scientific article

Kinetics and epigenetics of retroviral silencing in mouse embryonic stem cells defined by deletion of the D4Z4 element

scientific article published on 11 June 2013

LCR-regulated transgene expression levels depend on the Oct-1 site in the AT-rich region of beta -globin intron-2.

scientific article published on 26 September 2002

MBNL proteins repress ES-cell-specific alternative splicing and reprogramming.

scientific article published on 05 June 2013

MECP2 Is Post-transcriptionally Regulated during Human Neurodevelopment by Combinatorial Action of RNA-Binding Proteins and miRNAs

scientific article published in October 2016

MECP2 isoform-specific vectors with regulated expression for Rett syndrome gene therapy

scientific article

MECP2e1 isoform mutation affects the form and function of neurons derived from Rett syndrome patient iPS cells

scientific article

Methylglyoxal couples metabolic and translational control of Notch signalling in mammalian neural stem cells

scientific article published on 24 April 2020

Modeling and rescue of the vascular phenotype of Williams-Beuren syndrome in patient induced pluripotent stem cells

scientific article published on 21 December 2012

Nuclear matrix association of the human beta-globin locus utilizing a novel approach to quantitative real-time PCR

scientific article published on June 2003

Open and closed domains in the mouse genome are configured as 10-nm chromatin fibres

scientific article

Optimizing neuronal differentiation from induced pluripotent stem cells to model ASD

scientific article published on 11 April 2014

Over-expression of either MECP2_e1 or MECP2_e2 in neuronally differentiated cells results in different patterns of gene expression

scientific article

Personalized Medicine in the Genomics Era: highlights from an international symposium on childhood heart disease

scientific article published on March 2012

Rapid transcriptional pulsing dynamics of high expressing retroviral transgenes in embryonic stem cells

scientific article (publication date: 2012)

Reprogramming progeria fibroblasts re-establishes a normal epigenetic landscape.

scientific article

Retroviral vector silencing during iPS cell induction: an epigenetic beacon that signals distinct pluripotent states

scientific article

Retrovirus silencer blocking by the cHS4 insulator is CTCF independent

scientific article

Retrovirus silencing and vector design: relevance to normal and cancer stem cells?

scientific article

Retrovirus silencing by an epigenetic TRIM.

scientific article published in October 2007

Retrovirus silencing, variegation, extinction, and memory are controlled by a dynamic interplay of multiple epigenetic modifications

scientific article published in July 2004

Rett syndrome induced pluripotent stem cell-derived neurons reveal novel neurophysiological alterations.

scientific article

SHANK2 mutations associated with autism spectrum disorder cause hyperconnectivity of human neurons

scientific article published on 25 March 2019

Silencing and variegation of gammaretrovirus and lentivirus vectors

scientific article

Spatiotemporal proteomic profiling of human cerebral development

scientific article

Stage-Specific Optimization of Activin/Nodal and BMP Signaling Promotes Cardiac Differentiation of Mouse and Human Pluripotent Stem Cell Lines ⬇️

scientific article (publication date: 4 February 2011)

Synaptic Dysfunction in Human Neurons With Autism-Associated Deletions in PTCHD1-AS

scientific article published on 29 July 2019

The Personal Genome Project Canada: findings from whole genome sequences of the inaugural 56 participants

scientific article published in February 2018

The beta-globin locus control region versus gene therapy vectors: a struggle for expression.

scientific article

The pluripotency factor Nanog regulates pericentromeric heterochromatin organization in mouse embryonic stem cells

scientific article published on 28 April 2016

Transgenic mouse overexpressing syntaxin-1A as a diabetes model

scientific article published in September 2005

Unexpected acceleration of type 1 diabetes by transgenic expression of B7-H1 in NOD mouse peri-islet glia

scientific article published on 3 June 2010

Whole genome sequencing delineates regulatory, copy number, and cryptic splice variants in early onset cardiomyopathy

scientific article published on 14 March 2022

Wide spectrum of neuronal and network phenotypes in human stem cell-derived excitatory neurons with Rett syndrome-associated MECP2 mutations

scientific article published in 2022

X-chromosome inactivation in rett syndrome human induced pluripotent stem cells

scientific article published on 23 March 2012

eGFP reporter genes silence LCRbeta-globin transgene expression via CpG dinucleotides

scientific article published in April 2005

iPS cells to model CDKL5-related disorders.

scientific article published on 13 July 2011

iPSC Technology: Platform for Drug Discovery

scientific article published on 01 May 2011

or human iPSC-derived neurons from individuals with autism develop hyperactive neuronal networks

scientific article published on 12 February 2019

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