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List of works by Flavio Rizzolio

4-Aryliden-2-methyloxazol-5(4H)-one as a new scaffold for selective reversible MAGL inhibitors

scientific article

A Guide to PIN1 Function and Mutations Across Cancers

scientific article published on 01 January 2018

A functional biological network centered on XRCC3: a new possible marker of chemoradiotherapy resistance in rectal cancer patients

scientific article

A patent review of Monoacylglycerol Lipase (MAGL) inhibitors (2013-2017).

scientific article

A susceptibility gene for premature ovarian failure (POF) maps to proximal Xq28

scientific article published on 28 July 2004

Alterations of the Plasma Peptidome Profiling in Colorectal Cancer Progression.

scientific article published on 17 September 2015

An Effective Multi-Stage Liposomal DNA Origami Nanosystem for In Vivo Cancer Therapy

scientific article published on 12 December 2019

An integrative approach for the identification of prognostic and predictive biomarkers in rectal cancer

scientific article published on 2 September 2015

An updated patent review of monoacylglycerol lipase (MAGL) inhibitors (2018-present)

scientific article published on 21 October 2020

Androgen receptor serine 81 mediates Pin1 interaction and activity

scientific article

Application of MM-PBSA Methods in Virtual Screening

scientific article published on 23 April 2020

Binding investigation and preliminary optimisation of the 3-amino-1,2,4-triazin-5(2H)-one core for the development of new Fyn inhibitors.

scientific article

Bottom-up synthesis of carbon nanoparticles with higher doxorubicin efficacy.

scientific article published on 13 January 2017

CDK inhibitors: from the bench to clinical trials.

scientific article published on March 2010

Cancer Extracellular Vesicles: Next-Generation Diagnostic and Drug Delivery Nanotools

scientific article published on 28 October 2020

Carbon Dots from Sugars and Ascorbic Acid: Role of the Precursors on Morphology, Properties, Toxicity, and Drug Uptake

scientific article published on 16 July 2018

Characterization of the Saffron Derivative Crocetin as an Inhibitor of Human Lactate Dehydrogenase 5 in the Antiglycolytic Approach against Cancer.

scientific article

Chromosomal rearrangements in Xq and premature ovarian failure: mapping of 25 new cases and review of the literature.

scientific article

Clinical predictive circulating peptides in rectal cancer patients treated with neoadjuvant chemoradiotherapy

scientific article published on August 2015

Combined effects of PI3K and SRC kinase inhibitors with imatinib on intracellular calcium levels, autophagy, and apoptosis in CML-PBL cells.

scientific article published on 8 August 2013

Computationally driven discovery of phenyl(piperazin-1-yl)methanone derivatives as reversible monoacylglycerol lipase (MAGL) inhibitors

scientific article published on 01 December 2019

Corrigendum to “Fluorescent molecularly imprinted nanogels for the detection of anticancer drugs in human plasma” [Biosens. Bioelectron. 86 (2016) 913–919]

scientific article published on 23 March 2017

Critical choices for modeling breast cancer in transgenic mouse models.

scientific article published on August 2012

Cyclic Ketoximes as Estrogen Receptor β Selective Agonists.

scientific article published on 2 May 2016

DNA Nanotechnology for Cancer Therapy

scientific article

Decellularized colorectal cancer matrix as bioactive microenvironment for in vitro 3D cancer research

scientific article

Development of terphenyl-2-methyloxazol-5(4H)-one derivatives as selective reversible MAGL inhibitors.

scientific article

Discovery of 1,5-Diphenylpyrazole-3-Carboxamide Derivatives as Potent, Reversible, and Selective Monoacylglycerol Lipase (MAGL) Inhibitors.

scientific article

Discovery of a new ATP-citrate lyase (ACLY) inhibitor identified by a pharmacophore-based virtual screening study

scientific article published on 25 May 2020

Discovery of long-chain salicylketoxime derivatives as monoacylglycerol lipase (MAGL) inhibitors

scientific article published on 16 August 2018

Dissecting Pin1 and phospho-pRb regulation.

scientific article published on January 2013

Editorial: Peptidyl-Prolyl Isomerases in Human Pathologies

scientific article published on 11 July 2019

Emerging molecular networks in Burkitt's lymphoma.

scientific article published on January 2013

Enhanced Chemotherapeutic Behavior of Open-Caged DNA@Doxorubicin Nanostructures for Cancer Cells

scientific article published on 29 May 2015

Epigenetic control of the critical region for premature ovarian failure on autosomal genes translocated to the X chromosome: a hypothesis.

scientific article published on 31 January 2007

Exosomal doxorubicin reduces the cardiac toxicity of doxorubicin

scientific article published on 30 September 2015

Exosomes increase the therapeutic index of doxorubicin in breast and ovarian cancer mouse models.

scientific article published on 25 August 2016

Extracellular Matrix and Colorectal Cancer: How Surrounding Microenvironment Affects Cancer Cell Behavior?

scientific article

First-of-its-kind STARD3 Inhibitor: In Silico Identification and Biological Evaluation as Anticancer Agent

scientific article published on 20 February 2019

Fluorescent Carbon Nanoparticles in Medicine for Cancer Therapy: An Update.

scientific article published on 28 December 2017

Fluorescent carbon nanoparticles in medicine for cancer therapy

scientific article

Fluorescent molecularly imprinted nanogels for the detection of anticancer drugs in human plasma

scientific article published on 26 July 2016

Gene and MicroRNA Expression Are Predictive of Tumor Response in Rectal Adenocarcinoma Patients Treated With Preoperative Chemoradiotherapy.

scientific article published on 25 May 2016

Highly conserved non-coding sequences and the 18q critical region for short stature: a common mechanism of disease?

scientific article

Highly selective salicylketoxime-based estrogen receptor β agonists display antiproliferative activities in a glioma model

scientific article

Hyaluronan esters drive Smad gene expression and signaling enhancing cardiogenesis in mouse embryonic and human mesenchymal stem cells

scientific article

Identification and characterization of a new reversible MAGL inhibitor

scientific article

Identification of new Fyn kinase inhibitors using a FLAP-based approach.

scientific article

Impact of DNA repair gene polymorphisms on the risk of biochemical recurrence after radiotherapy and overall survival in prostate cancer

scientific article

Inorganic Nanoparticles for Cancer Therapy: A Transition from Lab to Clinic

scientific article published on 01 January 2018

Liposomal delivery of a Pin1 inhibitor complexed with cyclodextrins as new therapy for high-grade serous ovarian cancer

scientific article published on 08 May 2018

MTHFR-1298 A>C (rs1801131) is a predictor of survival in two cohorts of stage II/III colorectal cancer patients treated with adjuvant fluoropyrimidine chemotherapy with or without oxaliplatin

scientific article published on 21 October 2014

Metabolomics biomarkers of frailty in elderly breast cancer patients.

scientific article published in July 2014

Nanomedicine in Cancer Pathology

scientific article published on 01 January 2018

New insight into structure-activity of furan-based salicylate synthase (MbtI) inhibitors as potential antitubercular agents

scientific article published on 01 December 2019

Optimization of a Benzoylpiperidine Class Identifies a Highly Potent and Selective Reversible Monoacylglycerol Lipase (MAGL) Inhibitor

scientific article published on 11 February 2019

Osteopontin controls endothelial cell migration in vitro and in excised human valvular tissue from patients with calcific aortic stenosis and controls ⬇️

scientific article published on August 1, 2011

Pathological Role of Peptidyl-Prolyl Isomerase Pin1 in the Disruption of Synaptic Plasticity in Alzheimer's Disease.

scientific article

Pharmaco-metabolomics: an emerging "omics" tool for the personalization of anticancer treatments and identification of new valuable therapeutic targets

scientific article

Pharmacometabolomics study identifies circulating spermidine and tryptophan as potential biomarkers associated with the complete pathological response to trastuzumab-paclitaxel neoadjuvant therapy in HER-2 positive breast cancer.

scientific article published on 19 May 2016

Pin1 and nuclear receptors: a new language?

scientific article published on September 2013

Polymer-Mediated Delivery of siRNAs to Hepatocellular Carcinoma: Variables Affecting Specificity and Effectiveness

scientific article published on 28 March 2018

Proof-of-Concept Multistage Biomimetic Liposomal DNA Origami Nanosystem for the Remote Loading of Doxorubicin

scientific article published on 31 January 2019

R-Roscovitine (Seliciclib) prevents DNA damage-induced cyclin A1 upregulation and hinders non-homologous end-joining (NHEJ) DNA repair

scientific article published on 4 August 2010

RB gene family: genome-wide ChIP approaches could open undiscovered roads.

scientific article published on April 2010

Rational Development of MAGL Inhibitors

scientific article published on 01 January 2018

Rational design, synthesis and anti-proliferative properties of new CB2 selective cannabinoid receptor ligands: an investigation of the 1,8-naphthyridin-2(1H)-one scaffold.

scientific article

Redox modulation of vitagenes via plant polyphenols and vitamin D: Novel insights for chemoprevention and therapeutic interventions based on organoid technology

scientific article published in 2021

Retinoblastoma tumor-suppressor protein phosphorylation and inactivation depend on direct interaction with Pin1.

scientific article

Self-Therapeutic Cobalt Hydroxide Nanosheets (Co(OH)<sub>2</sub> NS) for Ovarian Cancer Therapy

scientific article published on 19 October 2021

Strategies for Delivery of siRNAs to Ovarian Cancer Cells

scientific article published on 22 October 2019

Strategies to optimize siRNA delivery to hepatocellular carcinoma cells.

scientific article published on 17 February 2017

Structural Optimization of 4-Chlorobenzoylpiperidine Derivatives for the Development of Potent, Reversible, and Selective Monoacylglycerol Lipase (MAGL) Inhibitors.

scientific article published on 3 November 2016

Synthesis and in-depth studies on the anticancer activity of novel palladacyclopentadienyl complexes stabilized by N-Heterocyclic carbene ligands

scientific article published on 22 June 2019

Targeting intracellular B2 receptors using novel cell-penetrating antagonists to arrest growth and induce apoptosis in human triple-negative breast cancer.

scientific article published on 5 January 2018

The Clinical translation of Organic Nanomaterials for Cancer Therapy: A Focus on Polymeric Nanoparticles, Micelles, Liposomes and Exosomes.

scientific article published on 29 August 2017

The History of Nanoscience and Nanotechnology: From Chemical-Physical Applications to Nanomedicine

scientific article published on 27 December 2019

The ablation of EZH2 uncovers its crucial role in rhabdomyosarcoma formation ⬇️

scientific article published on September 14, 2012

The prolyl isomerase Pin1 acts synergistically with CDK2 to regulate the basal activity of estrogen receptor α in breast cancer

scientific article

Virtual screening identifies a PIN1 inhibitor with possible antiovarian cancer effects

scientific article published on 29 January 2019

X chromosome and ovarian failure.

scientific article

pRb controls estrogen receptor alpha protein stability and activity.

scientific article published on June 2013

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