List of works - Fabio Parmeggiani

A Rapid and High-Throughput Assay for the Estimation of Conversions of Ene-Reductase-Catalysed Reactions

scientific article published on 24 June 2015

Adenylation Activity of Carboxylic Acid Reductases Enables the Synthesis of Amides

scientific article

Asymmetric Bioreduction of β-Acylaminonitroalkenes: Easy Access to Chiral Building Blocks with Two Vicinal Nitrogen-Containing Functional Groups

scientific article published on 29 May 2017

Biocatalysed reduction of carboxylic acids to primary alcohols in aqueous medium: A novel synthetic capability of the zygomycete fungus Syncephalastrum racemosum

Biocatalytic synthesis of chiral cyclic γ-oxoesters by sequential C–H hydroxylation, alcohol oxidation and alkene reduction

scientific article published in 2017

Biocatalytic transamination with near-stoichiometric inexpensive amine donors mediated by bifunctional mono- and di-amine transaminases

Biocatalyzed Enantioselective Reduction of Activated C=C Bonds: Synthesis of Enantiomerically Enriched α-Halo-β-arylpropionic Acids

scientific article published on 17 June 2011

Biochemical characterisation of an α1,4 galactosyltransferase from Neisseria weaveri for the synthesis of α1,4-linked galactosides

scientific article published on 07 April 2020

Biomimetic synthesis of 2-substituted N-heterocycle alkaloids by one-pot hydrolysis, transamination and decarboxylative Mannich reaction

scholarly article by James L. Galman et al published 14 October 2018 in Chemical Communications

Biosynthesis and Characterization of Copper Nanoparticles Using Shewanella oneidensis: Application for Click Chemistry

scientific article published on 23 January 2018

Biotechnological Development of a Practical Synthesis of Ethyl (S)-2-Ethoxy-3-(p-methoxyphenyl)propanoate (EEHP): Over 100-Fold Productivity Increase from Yeast Whole Cells to Recombinant Isolated Enzymes

article

Biotechnological synthesis of Pd/Ag and Pd/Au nanoparticles for enhanced Suzuki-Miyaura cross-coupling activity

scientific article published in November 2021

Cascade Coupling of Ene Reductases with Alcohol Dehydrogenases: Enantioselective Reduction of Prochiral Unsaturated Aldehydes

scientific article published on 28 February 2012

Cascade Coupling of Ene-Reductases and ω-Transaminases for the Stereoselective Synthesis of Diastereomerically Enriched Amines

scientific article published on 10 August 2015

Characterisation of a Bacterial Galactokinase with High Activity and Broad Substrate Tolerance for Chemoenzymatic Synthesis of 6-Aminogalactose-1-Phosphate and Analogues

scientific article published on 29 November 2017

Chemoenzymatic Synthesis of Optically Pure l- and d-Biarylalanines through Biocatalytic Asymmetric Amination and Palladium-Catalyzed Arylation

scholarly article by Syed T. Ahmed et al published 13 August 2015 in ACS Catalysis

Discovery and Investigation of Mutase-like Activity in a Phenylalanine Ammonia Lyase from Anabaena variabilis.

scientific article

Enantioselective CC bond reduction of unsaturated α-chloro esters by old yellow enzymes

scientific article published in July 2011

Enantioselective Synthesis of (R)-2-Arylpropanenitriles Catalysed by Ene-Reductases in Aqueous Media and in Biphasic Ionic Liquid-Water Systems

scientific article published on 8 July 2014

Engineered Aminotransferase for the Production of d -Phenylalanine Derivatives Using Biocatalytic Cascades

Engineered Ammonia Lyases for the Production of Challenging Electron-Rich l-Phenylalanines

article published in 2018

Enoate Reductase-Mediated Preparation of Methyl (S)-2-Bromobutanoate, a Useful Key Intermediate for the Synthesis of Chiral Active Pharmaceutical Ingredients

scientific article published on 6 September 2011

Enzymatic synthesis of N-acetyllactosamine from lactose enabled by recombinant β1,4-galactosyltransferases

scientific article published on 01 June 2019

Enzyme-mediated synthesis of EEHP and EMHP, useful pharmaceutical intermediates of PPAR agonists

Fear of the Dark: Diazo Printing by Photochemical Decomposition of Aryldiazonium Tetrafluoroborates

article by Fabio Parmeggiani published 28 February 2014 in Journal of Chemical Education

Identification of fungal ene-reductase activity by means of a functional screening

scientific article published on 4 February 2015

Intensified biocatalytic production of enantiomerically pure halophenylalanines from acrylic acids using ammonium carbamate as the ammonia source

Investigation of the stereochemical course of ene reductase-catalysed reactions by deuterium labelling.

scientific article published on 12 February 2015

Kinetic Resolution of Aromatic β-Amino Acids Using a Combination of Phenylalanine Ammonia Lyase and Aminomutase Biocatalysts

Multi-Enzymatic Cascade Procedures for the Synthesis of Chiral Odorous Molecules

Multi-enzyme cascade synthesis of the most odorous stereoisomers of the commercial odorant Muguesia®

scientific article published in April 2015

New stereospecific synthesis of Tesaglitazar and Navaglitazar precursors

Old Yellow Enzyme-mediated reduction of β-cyano-α,β-unsaturated esters for the synthesis of chiral building blocks: stereochemical analysis of the reaction

scientific article published in 2013

On the stereochemistry of the Baker's Yeast-mediated reduction of regioisomeric unsaturated aldehydes: Examples of enantioselectivity switch promoted by substrate-engineering

One-Pot Biocatalytic Cascade Reduction of Cyclic Enimines for the Preparation of Diastereomerically Enriched N-Heterocycles

scientific article published on 26 November 2019

One-Pot Biocatalytic Double Oxidation of α-Isophorone for the Synthesis of Ketoisophorone

One-Pot Multi-Enzymatic Synthesis of the Four Stereoisomers of 4-Methylheptan-3-ol.

scientific article

Opposite Enantioselectivity in the Bioreduction of (Z )-β-Aryl-β-cyanoacrylates Mediated by the Tryptophan 116 Mutants of Old Yellow Enzyme 1: Synthetic Approach to (R )- and (S )-β-Aryl-γ-lactams

scientific article published on 13 May 2015

Preparation and Luminescence Thermochromism of Tetranuclear Copper(I)–Pyridine–Iodide Clusters

Productivity enhancement of CC bioreductions by coupling the in situ substrate feeding product removal technology with isolated enzymes

scientific article published in 2012

Rapid and sensitive monitoring of biocatalytic reactions using ion mobility mass spectrometry.

scientific article published on 21 March 2016

Rationalisation of the stereochemical outcome of ene-reductase-mediated bioreduction of α,β-difunctionalised alkenes

scientific article published in March 2014

Real-Time Screening of Biocatalysts in Live Bacterial Colonies.

scientific article

Single-Biocatalyst Synthesis of Enantiopured-Arylalanines Exploiting an Engineeredd-Amino Acid Dehydrogenase

Stereochemical Outcome of the Biocatalysed Reduction of Activated Tetrasubstituted Olefins by Old Yellow Enzymes 1-3

scientific article published in January 2012

Steric Effects on the Stereochemistry of Old Yellow Enzyme-Mediated Reductions of Unsaturated Diesters: Flipping of the Substrate within the Enzyme Active Site Induced by Structural Modifications

scientific article published on 5 October 2012

Substrate Scope Evaluation of the Enantioselective Reduction of β-Alkyl-β-arylnitroalkenes by Old Yellow Enzymes 1-3 for Organic Synthesis Applications

scientific article published on 15 December 2015

Substrate scope and synthetic applications of the enantioselective reduction of α-alkyl-β-arylenones mediated by Old Yellow Enzymes.

scientific article

Substrate-engineering approach to the stereoselective chemo-multienzymatic cascade synthesis of Nicotiana tabacum lactone

scientific article published in April 2015

Synthesis of D- and L-phenylalanine derivatives by phenylalanine ammonia lyases: a multienzymatic cascade process

scientific article published on 26 February 2015

Synthesis of Enantiomerically Enriched 2-Hydroxymethylalkanoic Acids by Oxidative Desymmetrisation of Achiral 1,3-Diols Mediated byAcetobacter aceti

Synthesis of Enantiomerically Pure Ring-Substituted l-Pyridylalanines by Biocatalytic Hydroamination

scientific article published on 21 October 2016

Synthesis of Robalzotan, Ebalzotan, and Rotigotine Precursors via the Stereoselective Multienzymatic Cascade Reduction of α,β-Unsaturated Aldehydes

scientific article published on 8 May 2013

Synthesis of copper catalysts for click chemistry from distillery wastewater using magnetically recoverable bionanoparticles

scientific article published in 2019

Synthetic and Therapeutic Applications of Ammonia-lyases and Aminomutases

scientific article

Telescopic one-pot condensation-hydroamination strategy for the synthesis of optically pure L-phenylalanines from benzaldehydes

The Bacterial Ammonia Lyase EncP: A Tunable Biocatalyst for the Synthesis of Unnatural Amino Acids

scientific article published on 01 October 2015

The characterisation of a galactokinase from Streptomyces coelicolor

scientific article published in January 2019

Zymophore identification enables the discovery of novel phenylalanine ammonia lyase enzymes

scientific article

List of works by Fabio Parmeggiani

A Rapid and High-Throughput Assay for the Estimation of Conversions of Ene-Reductase-Catalysed Reactions

Adenylation Activity of Carboxylic Acid Reductases Enables the Synthesis of Amides

Asymmetric Bioreduction of β-Acylaminonitroalkenes: Easy Access to Chiral Building Blocks with Two Vicinal Nitrogen-Containing Functional Groups

Biocatalysed reduction of carboxylic acids to primary alcohols in aqueous medium: A novel synthetic capability of the zygomycete fungus Syncephalastrum racemosum

Biocatalytic synthesis of chiral cyclic γ-oxoesters by sequential C–H hydroxylation, alcohol oxidation and alkene reduction

Biocatalytic transamination with near-stoichiometric inexpensive amine donors mediated by bifunctional mono- and di-amine transaminases

Biocatalyzed Enantioselective Reduction of Activated C=C Bonds: Synthesis of Enantiomerically Enriched α-Halo-β-arylpropionic Acids

Biochemical characterisation of an α1,4 galactosyltransferase from Neisseria weaveri for the synthesis of α1,4-linked galactosides

Biomimetic synthesis of 2-substituted N-heterocycle alkaloids by one-pot hydrolysis, transamination and decarboxylative Mannich reaction

Biosynthesis and Characterization of Copper Nanoparticles Using Shewanella oneidensis: Application for Click Chemistry

Biotechnological Development of a Practical Synthesis of Ethyl (S)-2-Ethoxy-3-(p-methoxyphenyl)propanoate (EEHP): Over 100-Fold Productivity Increase from Yeast Whole Cells to Recombinant Isolated Enzymes

Biotechnological synthesis of Pd/Ag and Pd/Au nanoparticles for enhanced Suzuki-Miyaura cross-coupling activity

Cascade Coupling of Ene Reductases with Alcohol Dehydrogenases: Enantioselective Reduction of Prochiral Unsaturated Aldehydes

Cascade Coupling of Ene-Reductases and ω-Transaminases for the Stereoselective Synthesis of Diastereomerically Enriched Amines

Characterisation of a Bacterial Galactokinase with High Activity and Broad Substrate Tolerance for Chemoenzymatic Synthesis of 6-Aminogalactose-1-Phosphate and Analogues

Chemoenzymatic Synthesis of Optically Pure l- and d-Biarylalanines through Biocatalytic Asymmetric Amination and Palladium-Catalyzed Arylation

Discovery and Investigation of Mutase-like Activity in a Phenylalanine Ammonia Lyase from Anabaena variabilis.

Enantioselective CC bond reduction of unsaturated α-chloro esters by old yellow enzymes

Enantioselective Synthesis of (R)-2-Arylpropanenitriles Catalysed by Ene-Reductases in Aqueous Media and in Biphasic Ionic Liquid-Water Systems

Engineered Aminotransferase for the Production of d -Phenylalanine Derivatives Using Biocatalytic Cascades

Engineered Ammonia Lyases for the Production of Challenging Electron-Rich l-Phenylalanines

Enoate Reductase-Mediated Preparation of Methyl (S)-2-Bromobutanoate, a Useful Key Intermediate for the Synthesis of Chiral Active Pharmaceutical Ingredients

Enzymatic synthesis of N-acetyllactosamine from lactose enabled by recombinant β1,4-galactosyltransferases

Enzyme-mediated synthesis of EEHP and EMHP, useful pharmaceutical intermediates of PPAR agonists

Fear of the Dark: Diazo Printing by Photochemical Decomposition of Aryldiazonium Tetrafluoroborates

Identification of fungal ene-reductase activity by means of a functional screening

Intensified biocatalytic production of enantiomerically pure halophenylalanines from acrylic acids using ammonium carbamate as the ammonia source

Investigation of the stereochemical course of ene reductase-catalysed reactions by deuterium labelling.

Kinetic Resolution of Aromatic β-Amino Acids Using a Combination of Phenylalanine Ammonia Lyase and Aminomutase Biocatalysts

Multi-Enzymatic Cascade Procedures for the Synthesis of Chiral Odorous Molecules

Multi-enzyme cascade synthesis of the most odorous stereoisomers of the commercial odorant Muguesia®

New stereospecific synthesis of Tesaglitazar and Navaglitazar precursors

Old Yellow Enzyme-mediated reduction of β-cyano-α,β-unsaturated esters for the synthesis of chiral building blocks: stereochemical analysis of the reaction

On the stereochemistry of the Baker's Yeast-mediated reduction of regioisomeric unsaturated aldehydes: Examples of enantioselectivity switch promoted by substrate-engineering

One-Pot Biocatalytic Cascade Reduction of Cyclic Enimines for the Preparation of Diastereomerically Enriched N-Heterocycles

One-Pot Biocatalytic Double Oxidation of α-Isophorone for the Synthesis of Ketoisophorone

One-Pot Multi-Enzymatic Synthesis of the Four Stereoisomers of 4-Methylheptan-3-ol.

Opposite Enantioselectivity in the Bioreduction of (Z )-β-Aryl-β-cyanoacrylates Mediated by the Tryptophan 116 Mutants of Old Yellow Enzyme 1: Synthetic Approach to (R )- and (S )-β-Aryl-γ-lactams

Preparation and Luminescence Thermochromism of Tetranuclear Copper(I)–Pyridine–Iodide Clusters

Productivity enhancement of CC bioreductions by coupling the in situ substrate feeding product removal technology with isolated enzymes

Rapid and sensitive monitoring of biocatalytic reactions using ion mobility mass spectrometry.

Rationalisation of the stereochemical outcome of ene-reductase-mediated bioreduction of α,β-difunctionalised alkenes

Real-Time Screening of Biocatalysts in Live Bacterial Colonies.

Single-Biocatalyst Synthesis of Enantiopured-Arylalanines Exploiting an Engineeredd-Amino Acid Dehydrogenase

Stereochemical Outcome of the Biocatalysed Reduction of Activated Tetrasubstituted Olefins by Old Yellow Enzymes 1-3

Steric Effects on the Stereochemistry of Old Yellow Enzyme-Mediated Reductions of Unsaturated Diesters: Flipping of the Substrate within the Enzyme Active Site Induced by Structural Modifications

Substrate Scope Evaluation of the Enantioselective Reduction of β-Alkyl-β-arylnitroalkenes by Old Yellow Enzymes 1-3 for Organic Synthesis Applications

Substrate scope and synthetic applications of the enantioselective reduction of α-alkyl-β-arylenones mediated by Old Yellow Enzymes.

Substrate-engineering approach to the stereoselective chemo-multienzymatic cascade synthesis of Nicotiana tabacum lactone

Synthesis of D- and L-phenylalanine derivatives by phenylalanine ammonia lyases: a multienzymatic cascade process

Synthesis of Enantiomerically Enriched 2-Hydroxymethylalkanoic Acids by Oxidative Desymmetrisation of Achiral 1,3-Diols Mediated byAcetobacter aceti

Synthesis of Enantiomerically Pure Ring-Substituted l-Pyridylalanines by Biocatalytic Hydroamination

Synthesis of Robalzotan, Ebalzotan, and Rotigotine Precursors via the Stereoselective Multienzymatic Cascade Reduction of α,β-Unsaturated Aldehydes

Synthesis of copper catalysts for click chemistry from distillery wastewater using magnetically recoverable bionanoparticles

Synthetic and Therapeutic Applications of Ammonia-lyases and Aminomutases

Telescopic one-pot condensation-hydroamination strategy for the synthesis of optically pure L-phenylalanines from benzaldehydes

The Bacterial Ammonia Lyase EncP: A Tunable Biocatalyst for the Synthesis of Unnatural Amino Acids

The characterisation of a galactokinase from Streptomyces coelicolor

Zymophore identification enables the discovery of novel phenylalanine ammonia lyase enzymes