List of works - Sarah R. Cooley

"Self"-reflection by KIR

scientific article published on 01 July 2009

161533 TriKE stimulates NK-cell function to overcome myeloid-derived suppressor cells in MDS

scientific article published on 01 June 2018

A Phase 1 Trial of CNDO-109-Activated Natural Killer Cells in Patients with High-Risk Acute Myeloid Leukemia.

scientific article published on 26 March 2018

A comparative appraisal of the resilience of marine social-ecological systems to mass mortalities of bivalves

scientific article published in 2017

A phase II study of allogeneic natural killer cell therapy to treat patients with recurrent ovarian and breast cancer

scientific article published on 20 September 2010

A randomized trial of one versus two doses of influenza vaccine after allogeneic transplantation

scientific article published on 29 August 2012

A subpopulation of human peripheral blood NK cells that lacks inhibitory receptors for self-MHC is developmentally immature

scientific article published on 28 March 2007

Achieving Breakthroughs in Global Hydrologic Science by Unlocking the Power of Multisensor, Multidisciplinary Earth Observations

scientific article published in 2021

Adaptive NK Cells Resist Regulatory T-cell Suppression Driven by IL37.

scientific article published on 21 May 2018

Adaptive NK Cells with Low TIGIT Expression Are Inherently Resistant to Myeloid-Derived Suppressor Cells

scientific article published on 8 August 2016

Adaptive NK cell reconstitution is associated with better clinical outcomes

scholarly article by Frank Cichocki et al published 24 January 2019 in JCI insight

Allogeneic NK cells eradicate myeloblasts but not neoplastic mast cells in systemic mastocytosis associated with acute myeloid leukemia.

scientific article published on 10 February 2017

Allogeneic natural killer cells for refractory lymphoma ⬇️

scientific article published on August 3, 2010

An Integrated Assessment Model for Helping the United States Sea Scallop (Placopecten magellanicus) Fishery Plan Ahead for Ocean Acidification and Warming

scientific article

An open-label phase 2 study of glycogen synthase kinase-3 inhibitor LY2090314 in patients with acute leukemia

scientific article

Association of iron overload with allogeneic hematopoietic cell transplantation outcomes: a prospective cohort study using R2-MRI-measured liver iron content

scientific article published on 18 June 2013

Cellular adoptive immunotherapy after autologous and allogeneic hematopoietic stem cell transplantation

scientific article published on January 2009

Challenges, insights and perspectives associated with using social-ecological science for marine conservation

scholarly article by Pierre Leenhardt published in October 2015

Clearance of acute myeloid leukemia by haploidentical natural killer cells is improved using IL-2 diphtheria toxin fusion protein

scientific article

Clinical production and therapeutic applications of alloreactive natural killer cells.

scientific article published on January 2012

Combined OX40L and mTOR blockade controls effector T cell activation while preserving Treg reconstitution after transplant

scientific article published in September 2017

Community-Level Actions that Can Address Ocean Acidification

Complete Remission with Reduction of High-Risk Clones following Haploidentical NK-Cell Therapy against MDS and AML.

scientific article published on 14 February 2018

Coral Reefs and People in a High-CO2 World: Where Can Science Make a Difference to People?

scientific article

Cytomegalovirus reactivation after allogeneic transplantation promotes a lasting increase in educated NKG2C+ natural killer cells with potent function

scientific article published on 16 December 2011

Decreased infections in recipients of unrelated donor hematopoietic cell transplantation from donors with an activating KIR genotype

scientific article

Donor Killer Cell Immunoglobulin-Like Receptor Genotype Does Not Improve Graft-versus-Leukemia Responses in Chronic Lymphocytic Leukemia after Unrelated Donor Transplant: A Center for International Blood and Marrow Transplant Research Analysis

scientific article published on 27 December 2018

Donor killer cell Ig-like receptor B haplotypes, recipient HLA-C1, and HLA-C mismatch enhance the clinical benefit of unrelated transplantation for acute myelogenous leukemia

scientific article

Donor selection for natural killer cell receptor genes leads to superior survival after unrelated transplantation for acute myelogenous leukemia

scientific article

Donors with group B KIR haplotypes improve relapse-free survival after unrelated hematopoietic cell transplantation for acute myelogenous leukemia

scientific article

Early Reconstitution of NK and γδ T Cells and Its Implication for the Design of Post-Transplant Immunotherapy

scientific article published on 2 March 2018

Exposure of Mediterranean Countries to Ocean Acidification

Fewer Circulating Natural Killer Cells 28 Days After Double Cord Blood Transplantation Predicts Inferior Survival and IL-15 Response

scientific article published on 30 October 2016

First in human phase I trial of 852A, a novel systemic toll-like receptor 7 agonist, to activate innate immune responses in patients with advanced cancer.

scientific article published on December 2007

First-in-human Phase 1 Clinical Study of the IL-15 Superagonist Complex ALT-803 to Treat Relapse after Transplantation

scientific article published on 20 February 2018

First-in-human trial of rhIL-15 and haploidentical natural killer cell therapy for advanced acute myeloid leukemia

scientific article published on 01 July 2019

GSK 3 inhibition drives maturation of NK cells and enhances their antitumor activity

scientific article published on 8 August 2017

Getting Ocean Acidification on Decision Makers’ To-Do Lists: Dissecting the Process Through Case Studies

scientific article published in 2015

Haploidentical natural killer cells induce remissions in non-Hodgkin lymphoma patients with low levels of immune-suppressor cells

scientific article

Hemolytic anemia due to passenger lymphocyte syndrome in solid malignancy patients treated with allogeneic natural killer cell products

scientific article published in November 2012

Human cytomegalovirus (CMV)-induced memory-like NKG2C(+) NK cells are transplantable and expand in vivo in response to recipient CMV antigen.

scientific article

IL15 Trispecific Killer Engagers (TriKE) Make Natural Killer Cells Specific to CD33+ Targets While Also Inducing Persistence, In Vivo Expansion, and Enhanced Function

scientific article published on 4 February 2016

Impact of cytomegalovirus (CMV) reactivation after umbilical cord blood transplantation

scientific article

KIR B donors improve the outcome for AML patients given reduced intensity conditioning and unrelated donor transplantation

scientific article published on 01 February 2020

KIR Donor Selection: Feasibility in Identifying better Donors

scientific article published on 24 August 2018

KIR reconstitution is altered by T cells in the graft and correlates with clinical outcomes after unrelated donor transplantation

scientific article published on 30 August 2005

Loss of T Follicular Helper Cells in the Peripheral Blood of Patients with Chronic Graft-versus-Host Disease

scientific article published on 12 January 2016

Lymphodepletion followed by donor lymphocyte infusion (DLI) causes significantly more acute graft-versus-host disease than DLI alone

scientific article

Missing KIR ligands are associated with less relapse and increased graft-versus-host disease (GVHD) following unrelated donor allogeneic HCT.

scientific article published on 22 February 2007

NK cell CD16 surface expression and function is regulated by a disintegrin and metalloprotease-17 (ADAM17).

scientific article published on 13 March 2013

NK cell education after allogeneic transplantation: dissociation between recovery of cytokine-producing and cytotoxic functions.

scientific article

Narratives can motivate environmental action: the Whiskey Creek ocean acidification story

scientific article

Natural Killer Cell Differentiation from Hematopoietic Stem Cells: A Comparative Analysis of Heparin- and Stromal Cell–Supported Methods ⬇️

scientific article published on December 7, 2011

Natural Killer Cell Homing and Persistence in the Bone Marrow After Adoptive Immunotherapy Correlates With Better Leukemia Control

scientific article published on 01 February 2019

Natural killer cell killing of acute myelogenous leukemia and acute lymphoblastic leukemia blasts by killer cell immunoglobulin-like receptor-negative natural killer cells after NKG2A and LIR-1 blockade

scientific article

Near surface meltwater storage in low-density bare ice of the Greenland ice sheet ablation zone

scholarly article by Matthew G. Cooper et al published 17 July 2017 in The Cryosphere discussions TCD

Negative effect of KIR alloreactivity in recipients of umbilical cord blood transplant depends on transplantation conditioning intensity

scientific article published on 27 March 2009

Novel CD19-targeted TriKE restores NK cell function and proliferative capacity in CLL

scientific article published on 01 March 2019

Nutrition and income from molluscs today imply vulnerability to ocean acidification tomorrow

Ocean and Coastal Acidification off New England and Nova Scotia

scientific article published in June 2015

Ocean-related options for climate change mitigation and adaptation: A machine learning-based evidence map protocol

Potential socioeconomic impacts from ocean acidification and climate change effects on Atlantic Canadian fisheries

scientific article published on 10 January 2020

Projected impacts of future climate change, ocean acidification, and management on the US Atlantic sea scallop (Placopecten magellanicus) fishery

scientific article published in PLoS ONE

Prolonged subcutaneous administration of 852A, a novel systemic toll‐like receptor 7 agonist, to activate innate immune responses in patients with advanced hematologic malignancies ⬇️

scientific article published on June 20, 2012

Recipient HLA-C Haplotypes and microRNA 148a/b Binding Sites Have No Impact on Allogeneic Hematopoietic Cell Transplantation Outcomes

scientific article published on 13 October 2016

Recipient T Cell Exhaustion and Successful Adoptive Transfer of Haploidentical Natural Killer Cells.

scientific article published on 29 November 2017

Reduced-Intensity Conditioning Followed by Related and Unrelated Allografts for Hematologic Malignancies: Expanded Analysis and Long-Term Follow-Up

scientific article published on 01 August 2018

Reduced-intensity conditioning followed by related allografts in hematologic malignancies: long-term outcomes most successful in indolent and aggressive non-Hodgkin lymphomas

scientific article

Regulation of Adaptive NK Cells and CD8 T Cells by HLA-C Correlates with Allogeneic Hematopoietic Cell Transplantation and with Cytomegalovirus Reactivation

scientific article published on 28 September 2015

Strategies to activate NK cells to prevent relapse and induce remission following hematopoietic stem cell transplantation

scientific article published on 22 January 2018

Systems analysis uncovers inflammatory Th/Tc17-driven modules during acute GVHD in monkey and human T cells

scientific article published on 06 October 2016

T cell-depleted partial matched unrelated donor transplant for advanced myeloid malignancy: KIR ligand mismatch and outcome.

scientific article published on 7 December 2011

The Past, Present, and Future of NK Cells in Hematopoietic Cell Transplantation and Adoptive Transfer

scientific article published on 03 June 2015

The association of CMV with NK-cell reconstitution depends on graft source: results from BMT CTN-0201 samples

scientific article published on 01 August 2019

The biology of NK cells and their receptors affects clinical outcomes after hematopoietic cell transplantation (HCT).

scientific article published on March 2014

Toll-like receptor-7 agonist administered subcutaneously in a prolonged dosing schedule in heavily pretreated recurrent breast, ovarian, and cervix cancers

scientific article published on 5 September 2010

Towards improved socio-economic assessments of ocean acidification's impacts

scientific article

Transcriptome analysis of GVHD reveals aurora kinase A as a targetable pathway for disease prevention

scientific article published on November 2015

Transient regulatory T-cell (Treg) depletion with IL-2 diphtheria toxin fusion protein enhances clearance of acute myeloid leukemia by haploidentical natural killer (NK) cells.

scientific article published on 7 November 2013

Trispecific killer engager CD16xIL15xCD33 potently induces NK cell activation and cytotoxicity against neoplastic mast cells

scientific article published on 01 July 2018

List of works by Sarah R. Cooley

"Self"-reflection by KIR

161533 TriKE stimulates NK-cell function to overcome myeloid-derived suppressor cells in MDS

A Phase 1 Trial of CNDO-109-Activated Natural Killer Cells in Patients with High-Risk Acute Myeloid Leukemia.

A comparative appraisal of the resilience of marine social-ecological systems to mass mortalities of bivalves

A phase II study of allogeneic natural killer cell therapy to treat patients with recurrent ovarian and breast cancer

A randomized trial of one versus two doses of influenza vaccine after allogeneic transplantation

A subpopulation of human peripheral blood NK cells that lacks inhibitory receptors for self-MHC is developmentally immature

Achieving Breakthroughs in Global Hydrologic Science by Unlocking the Power of Multisensor, Multidisciplinary Earth Observations

Adaptive NK Cells Resist Regulatory T-cell Suppression Driven by IL37.

Adaptive NK Cells with Low TIGIT Expression Are Inherently Resistant to Myeloid-Derived Suppressor Cells

Adaptive NK cell reconstitution is associated with better clinical outcomes

Allogeneic NK cells eradicate myeloblasts but not neoplastic mast cells in systemic mastocytosis associated with acute myeloid leukemia.

Allogeneic natural killer cells for refractory lymphoma ⬇️

An Integrated Assessment Model for Helping the United States Sea Scallop (Placopecten magellanicus) Fishery Plan Ahead for Ocean Acidification and Warming

An open-label phase 2 study of glycogen synthase kinase-3 inhibitor LY2090314 in patients with acute leukemia

Association of iron overload with allogeneic hematopoietic cell transplantation outcomes: a prospective cohort study using R2-MRI-measured liver iron content

Cellular adoptive immunotherapy after autologous and allogeneic hematopoietic stem cell transplantation

Challenges, insights and perspectives associated with using social-ecological science for marine conservation

Clearance of acute myeloid leukemia by haploidentical natural killer cells is improved using IL-2 diphtheria toxin fusion protein

Clinical production and therapeutic applications of alloreactive natural killer cells.

Combined OX40L and mTOR blockade controls effector T cell activation while preserving Treg reconstitution after transplant

Community-Level Actions that Can Address Ocean Acidification

Complete Remission with Reduction of High-Risk Clones following Haploidentical NK-Cell Therapy against MDS and AML.

Coral Reefs and People in a High-CO2 World: Where Can Science Make a Difference to People?

Cytomegalovirus reactivation after allogeneic transplantation promotes a lasting increase in educated NKG2C+ natural killer cells with potent function

Decreased infections in recipients of unrelated donor hematopoietic cell transplantation from donors with an activating KIR genotype

Donor Killer Cell Immunoglobulin-Like Receptor Genotype Does Not Improve Graft-versus-Leukemia Responses in Chronic Lymphocytic Leukemia after Unrelated Donor Transplant: A Center for International Blood and Marrow Transplant Research Analysis

Donor killer cell Ig-like receptor B haplotypes, recipient HLA-C1, and HLA-C mismatch enhance the clinical benefit of unrelated transplantation for acute myelogenous leukemia

Donor selection for natural killer cell receptor genes leads to superior survival after unrelated transplantation for acute myelogenous leukemia

Donors with group B KIR haplotypes improve relapse-free survival after unrelated hematopoietic cell transplantation for acute myelogenous leukemia

Early Reconstitution of NK and γδ T Cells and Its Implication for the Design of Post-Transplant Immunotherapy

Exposure of Mediterranean Countries to Ocean Acidification

Fewer Circulating Natural Killer Cells 28 Days After Double Cord Blood Transplantation Predicts Inferior Survival and IL-15 Response

First in human phase I trial of 852A, a novel systemic toll-like receptor 7 agonist, to activate innate immune responses in patients with advanced cancer.

First-in-human Phase 1 Clinical Study of the IL-15 Superagonist Complex ALT-803 to Treat Relapse after Transplantation

First-in-human trial of rhIL-15 and haploidentical natural killer cell therapy for advanced acute myeloid leukemia

GSK 3 inhibition drives maturation of NK cells and enhances their antitumor activity

Getting Ocean Acidification on Decision Makers’ To-Do Lists: Dissecting the Process Through Case Studies

Haploidentical natural killer cells induce remissions in non-Hodgkin lymphoma patients with low levels of immune-suppressor cells

Hemolytic anemia due to passenger lymphocyte syndrome in solid malignancy patients treated with allogeneic natural killer cell products

Human cytomegalovirus (CMV)-induced memory-like NKG2C(+) NK cells are transplantable and expand in vivo in response to recipient CMV antigen.

IL15 Trispecific Killer Engagers (TriKE) Make Natural Killer Cells Specific to CD33+ Targets While Also Inducing Persistence, In Vivo Expansion, and Enhanced Function

Impact of cytomegalovirus (CMV) reactivation after umbilical cord blood transplantation

KIR B donors improve the outcome for AML patients given reduced intensity conditioning and unrelated donor transplantation

KIR Donor Selection: Feasibility in Identifying better Donors

KIR reconstitution is altered by T cells in the graft and correlates with clinical outcomes after unrelated donor transplantation

Loss of T Follicular Helper Cells in the Peripheral Blood of Patients with Chronic Graft-versus-Host Disease

Lymphodepletion followed by donor lymphocyte infusion (DLI) causes significantly more acute graft-versus-host disease than DLI alone

Missing KIR ligands are associated with less relapse and increased graft-versus-host disease (GVHD) following unrelated donor allogeneic HCT.

NK cell CD16 surface expression and function is regulated by a disintegrin and metalloprotease-17 (ADAM17).

NK cell education after allogeneic transplantation: dissociation between recovery of cytokine-producing and cytotoxic functions.

Narratives can motivate environmental action: the Whiskey Creek ocean acidification story

Natural Killer Cell Differentiation from Hematopoietic Stem Cells: A Comparative Analysis of Heparin- and Stromal Cell–Supported Methods ⬇️

Natural Killer Cell Homing and Persistence in the Bone Marrow After Adoptive Immunotherapy Correlates With Better Leukemia Control

Natural killer cell killing of acute myelogenous leukemia and acute lymphoblastic leukemia blasts by killer cell immunoglobulin-like receptor-negative natural killer cells after NKG2A and LIR-1 blockade

Near surface meltwater storage in low-density bare ice of the Greenland ice sheet ablation zone

Negative effect of KIR alloreactivity in recipients of umbilical cord blood transplant depends on transplantation conditioning intensity

Novel CD19-targeted TriKE restores NK cell function and proliferative capacity in CLL

Nutrition and income from molluscs today imply vulnerability to ocean acidification tomorrow

Ocean and Coastal Acidification off New England and Nova Scotia

Ocean-related options for climate change mitigation and adaptation: A machine learning-based evidence map protocol

Potential socioeconomic impacts from ocean acidification and climate change effects on Atlantic Canadian fisheries

Projected impacts of future climate change, ocean acidification, and management on the US Atlantic sea scallop (Placopecten magellanicus) fishery

Prolonged subcutaneous administration of 852A, a novel systemic toll‐like receptor 7 agonist, to activate innate immune responses in patients with advanced hematologic malignancies ⬇️

Recipient HLA-C Haplotypes and microRNA 148a/b Binding Sites Have No Impact on Allogeneic Hematopoietic Cell Transplantation Outcomes

Recipient T Cell Exhaustion and Successful Adoptive Transfer of Haploidentical Natural Killer Cells.

Reduced-Intensity Conditioning Followed by Related and Unrelated Allografts for Hematologic Malignancies: Expanded Analysis and Long-Term Follow-Up

Reduced-intensity conditioning followed by related allografts in hematologic malignancies: long-term outcomes most successful in indolent and aggressive non-Hodgkin lymphomas

Regulation of Adaptive NK Cells and CD8 T Cells by HLA-C Correlates with Allogeneic Hematopoietic Cell Transplantation and with Cytomegalovirus Reactivation

Strategies to activate NK cells to prevent relapse and induce remission following hematopoietic stem cell transplantation

Systems analysis uncovers inflammatory Th/Tc17-driven modules during acute GVHD in monkey and human T cells

T cell-depleted partial matched unrelated donor transplant for advanced myeloid malignancy: KIR ligand mismatch and outcome.

The Past, Present, and Future of NK Cells in Hematopoietic Cell Transplantation and Adoptive Transfer

The association of CMV with NK-cell reconstitution depends on graft source: results from BMT CTN-0201 samples

The biology of NK cells and their receptors affects clinical outcomes after hematopoietic cell transplantation (HCT).

Toll-like receptor-7 agonist administered subcutaneously in a prolonged dosing schedule in heavily pretreated recurrent breast, ovarian, and cervix cancers

Towards improved socio-economic assessments of ocean acidification's impacts

Transcriptome analysis of GVHD reveals aurora kinase A as a targetable pathway for disease prevention

Transient regulatory T-cell (Treg) depletion with IL-2 diphtheria toxin fusion protein enhances clearance of acute myeloid leukemia by haploidentical natural killer (NK) cells.