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List of works by Mark Chiang

Cancer genetics: activated notch takes center stage in T-cell leukemogenesis.

scientific article

Critical roles of NOTCH1 in acute T-cell lymphoblastic leukemia ⬇️

scientific article published on 05 August 2011

Cutting Edge: Codeletion of the Ras GTPase-Activating Proteins (RasGAPs) Neurofibromin 1 and p120 RasGAP in T Cells Results in the Development of T Cell Acute Lymphoblastic Leukemia.

scientific article published on 22 May 2015

Deletion-based mechanisms of Notch1 activation in T-ALL: key roles for RAG recombinase and a conserved internal translational start site in Notch1.

scientific article

Divergent effects of supraphysiologic Notch signals on leukemia stem cells and hematopoietic stem cells

scientific article published on 31 October 2012

High selective pressure for Notch1 mutations that induce Myc in T-cell acute lymphoblastic leukemia.

scientific article published on 26 September 2016

Identification of a conserved negative regulatory sequence that influences the leukemogenic activity of NOTCH1

scientific article

NOTCH1 promotes T cell leukemia-initiating activity by RUNX-mediated regulation of PKC-θ and reactive oxygen species.

scientific article published on 21 October 2012

Oncogenic Notch signaling in T-cell and B-cell lymphoproliferative disorders.

scientific article published on 28 April 2016

Pre-TCR signaling inactivates Notch1 transcription by antagonizing E2A.

scientific article published on July 2009

Stage-specific roles for Zmiz1 in Notch-dependent steps of early T-cell development

scientific article published on 03 August 2018

The PIAS-like Coactivator Zmiz1 Is a Direct and Selective Cofactor of Notch1 in T Cell Development and Leukemia

scientific journal article

Transient responses to NOTCH and TLX1/HOX11 inhibition in T-cell acute lymphoblastic leukemia/lymphoma

scientific article

Whole-genome sequencing identifies recurrent somatic NOTCH2 mutations in splenic marginal zone lymphoma.

scientific article

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