List of works by Andrey Parkhitko

Autophagy-dependent metabolic reprogramming sensitizes TSC2-deficient cells to the antimetabolite 6-aminonicotinamide

scientific article

Autophagy: an 'Achilles' heel of tumorigenesis in TSC and LAM.

scientific article published on November 2011

Blocking p62-dependent SMN degradation ameliorates spinal muscular atrophy disease phenotypes

Cross-species identification of PIP5K1-, splicing- and ubiquitin-related pathways as potential targets for RB1-deficient cells

scientific article published on 16 February 2021

Direct inhibition of oncogenic KRAS by hydrocarbon-stapled SOS1 helices

scientific article

Downregulation of the tyrosine degradation pathway extends <i>Drosophila</i> lifespan

scientific article published on 15 December 2020

Estradiol and mTORC2 cooperate to enhance prostaglandin biosynthesis and tumorigenesis in TSC2-deficient LAM cells

scientific article published on 06 January 2014

Faslodex inhibits estradiol-induced extracellular matrix dynamics and lung metastasis in a model of lymphangioleiomyomatosis.

scientific article published on July 2013

Folliculin regulates cell-cell adhesion, AMPK, and mTORC1 in a cell-type-specific manner in lung-derived cells.

scientific article

High-throughput drug screen identifies chelerythrine as a selective inducer of death in a TSC2-null setting.

scientific article

Interaction of Epstein-Barr virus latent membrane protein 1 with SCFHOS/beta-TrCP E3 ubiquitin ligase regulates extent of NF-kappaB activation.

scientific article published on 30 September 2003

Kinase mTOR: regulation and role in maintenance of cellular homeostasis, tumor development, and aging.

scientific article published on February 2014

Methionine metabolism and methyltransferases in the regulation of aging and lifespan extension across species

scientific article published on 28 August 2019

Targeted deletion of Tsc1 causes fatal cardiomyocyte hyperplasia independently of afterload

scientific article published on 7 November 2014

Targeting metabolic pathways for extension of lifespan and healthspan across multiple species

scientific article published on 05 October 2020

Tissue-specific down-regulation of S-adenosyl-homocysteine via suppression of dAhcyL1/dAhcyL2 extends health span and life span in Drosophila

scientific article published on 16 June 2016

p62/SQSTM1 Cooperates with Hyperactive mTORC1 to Regulate Glutathione Production, Maintain Mitochondrial Integrity, and Promote Tumorigenesis.

scientific article published on 16 May 2017

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