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List of works by Kristina M Cook

A substrate-driven allosteric switch that enhances PDI catalytic activity

scientific article

A zebrafish model of tuberculosis comorbidity and the effects of HIF-activating intervention

scientific article published on 11 July 2020

Allosteric control of βII-tryptase by a redox active disulfide bond

scientific article published on 18 October 2013

Asparaginyl hydroxylation of the Notch ankyrin repeat domain by factor inhibiting hypoxia-inducible factor

scientific article

Autoregulation of von Willebrand factor function by a disulfide bond switch.

scientific article published on 28 February 2018

Control of blood proteins by functional disulfide bonds.

scientific article published on 12 February 2014

Epidithiodiketopiperazines (ETPs) exhibit in vitro antiangiogenic and in vivo antitumor activity by disrupting the HIF-1α/p300 complex in a preclinical model of prostate cancer

scientific article

Epidithiodiketopiperazines block the interaction between hypoxia-inducible factor-1alpha (HIF-1alpha) and p300 by a zinc ejection mechanism

scientific article published on 09 July 2009

Evaluation of a potential redox switch in blood coagulation tenase

Hypoxia, metabolism, and the circadian clock: new links to overcome radiation resistance in high-grade gliomas

scientific article published on 07 July 2020

Inhibition of the HIF1α-p300 interaction by quinone- and indandione-mediated ejection of structural Zn(II).

scientific article

Models of intermittent hypoxia and obstructive sleep apnea: molecular pathways and their contribution to cancer

scientific article published on 11 July 2018

Obstructive Sleep Apnea Activates HIF-1 in a Hypoxia Dose-Dependent Manner in HCT116 Colorectal Carcinoma Cells

scientific article published on 21 January 2019

Post-translational control of protein function by disulfide bond cleavage.

scientific article published on 15 February 2013

Preclinical Evaluation of Discorhabdins in Antiangiogenic and Antitumor Models

scientific article published on 19 July 2018

Screening and Biological Effects of Marine Pyrroloiminoquinone Alkaloids: Potential Inhibitors of the HIF-1α/p300 Interaction.

scientific article published on 3 May 2016

Structural Elucidation and Synthesis of Eudistidine A: An Unusual Polycyclic Marine Alkaloid that Blocks Interaction of the Protein Binding Domains of p300 and HIF-1α

scientific article published on 20 April 2015

Synthesis and cytotoxicity of novel sansalvamide A derivatives

scientific article published on 01 August 2005

The Cancer Clock Is (Not) Ticking: Links between Circadian Rhythms and Cancer

scientific article published on 20 September 2019

Zinc is a potent and specific inhibitor of IFN-λ3 signalling.

scientific article

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