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List of works by Brenna Osborne

A Novel Purification Procedure for Active Recombinant Human DPP4 and the Inability of DPP4 to Bind SARS-CoV-2

scientific article published on 18 November 2020

A novel small molecule that kills a subset of MLL-rearranged leukemia cells by inducing mitochondrial dysfunction

scientific article published on 22 January 2019

A rare variant in human fibroblast activation protein associated with ER stress, loss of enzymatic function and loss of cell surface localisation

scientific article published on 06 April 2014

A selective inhibitor of ceramide synthase 1 reveals a novel role in fat metabolism

scientific article published in Nature Communications

ARDD 2020: from aging mechanisms to interventions

scientific article published on 30 December 2020

Akt activation increases cellular cholesterol by promoting the proteasomal degradation of Niemann-Pick C1.

scientific article published on 17 August 2015

Are sirtuin deacylase enzymes important modulators of mitochondrial energy metabolism?

scientific article published on 27 August 2013

Contrasting metabolic effects of medium- versus long-chain fatty acids in skeletal muscle

scientific article published on 27 September 2013

Disparate metabolic response to fructose feeding between different mouse strains

scientific article

Human Exonuclease 1 (EXO1) Regulatory Functions in DNA Replication with Putative Roles in Cancer ⬇️

scientific article published on 25 December 2018

Impairment of an Endothelial NAD+-H2S Signaling Network Is a Reversible Cause of Vascular Aging.

scientific article published in March 2018

NAD(+) : a key metabolic regulator with great therapeutic potential

scientific article

ORP5 localizes to ER-lipid droplet contacts and regulates the level of PI(4)P on lipid droplets

scientific article published on 01 January 2020

PPARα-independent actions of omega-3 PUFAs contribute to their beneficial effects on adiposity and glucose homeostasis

scientific article

Pathways of Acetyl-CoA Metabolism Involved in the Reversal of Palmitate-Induced Glucose Production by Metformin and Salicylate.

scientific article published on 29 September 2016

Protein hypoacylation induced by Sirt5 overexpression has minimal metabolic effect in mice

article

Quantitation of fibroblast activation protein (FAP)-specific protease activity in mouse, baboon and human fluids and organs.

scientific article published on 08 December 2013

Regulation of glucose homeostasis and insulin action by ceramide acyl-chain length: A beneficial role for very long-chain sphingolipid species.

scientific article published on 31 August 2016

Regulation of mitochondrial metabolism in murine skeletal muscle by the medium-chain fatty acid receptor Gpr84

scientific article published on 15 August 2019

Repurposing Drugs to Target the Diabetes Epidemic

scientific article published on 18 February 2016

Snail-Overexpression Induces Epithelial-mesenchymal Transition and Metabolic Reprogramming in Human Pancreatic Ductal Adenocarcinoma and Non-tumorigenic Ductal Cells

scientific article published on 08 June 2019

The dipeptidyl peptidase IV family in cancer and cell biology.

scientific article published on 13 January 2010

The role of mitochondrial sirtuins in health and disease

scientific article published on 6 May 2016

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