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List of works by Rachelle S Singleton

DNA cross-links in human tumor cells exposed to the prodrug PR-104A: relationships to hypoxia, bioreductive metabolism, and cytotoxicity.

scientific article

OGFOD1 catalyzes prolyl hydroxylation of RPS23 and is involved in translation control and stress granule formation

scientific article

Quantitative mass spectrometry reveals dynamics of factor-inhibiting hypoxia-inducible factor-catalyzed hydroxylation.

scientific article

Relationships between reductive metabolism, DNA damage and antitumour activity of the hypoxia-activated prodrug PR-104 in preclinical models ⬇️

2008 doctoral thesis by Rachelle Singleton at University of Auckland

The FIH hydroxylase is a cellular peroxide sensor that modulates HIF transcriptional activity

scientific article published in March 2012

The bioreductive prodrug PR-104A is activated under aerobic conditions by human aldo-keto reductase 1C3

scientific article

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