List of works - Jinpeng Sun

Ablation of somatostatin cells leads to impaired pancreatic islet function and neonatal death in rodents.

scientific article

Allosteric mechanisms underlie GPCR signaling to SH3-domain proteins through arrestin

scientific article published on 17 August 2018

Allosteric modulation of the catalytic VYD loop in Slingshot by its N-terminal domain underlies both Slingshot auto-inhibition and activation

scientific article published on 28 August 2018

Combinatorial inhibition of PTPN12-regulated receptors leads to a broadly effective therapeutic strategy in triple-negative breast cancer.

scientific article published on 26 March 2018

Computational strategy for bound state structure prediction in structure-based virtual screening: a case study of protein tyrosine phosphatase receptor type O inhibitors

scientific article published on 19 October 2018

Correction: Allosteric modulation of the catalytic VYD loop in Slingshot by its N-terminal domain underlies both Slingshot auto-inhibition and activation

scientific article published in 2019

Crystal structure and catalytic activity of the PPM1K N94K mutant

scientific article published on 03 January 2019

DeSiphering receptor core-induced and ligand-dependent conformational changes in arrestin via genetic encoded trimethylsilyl 1H-NMR probe

scientific article published on 25 September 2020

Differences in the H2S-induced quantal release of catecholamine in adrenal chromaffin cells of neonatal and adult rats

scientific article

Discovery of novel FFA4 (GPR120) receptor agonists with β-arrestin2-biased characteristics.

scientific article published on 14 December 2015

Elevation of JAML Promotes Diabetic Kidney Disease by Modulating Podocyte Lipid Metabolism

scientific article published on 04 November 2020

Function and therapeutic potential of GPCRs in epididymis

scientific article published on 09 September 2020

Genetically Encoded Fluorescent Amino Acid for Monitoring Protein Interactions through FRET

scientific article published on 13 November 2019

Global phosphorylation analysis of beta-arrestin-mediated signaling downstream of a seven transmembrane receptor (7TMR).

scientific article

Gpr97 Exacerbates AKI by Mediating Sema3A Signaling

scientific article published on 12 March 2018

Gq activity- and β-arrestin-1 scaffolding-mediated ADGRG2/CFTR coupling are required for male fertility.

scientific article

H2S induces catecholamine secretion in rat adrenal chromaffin cells

scientific article published on 25 July 2012

Identification and structure-function analyses of an allosteric inhibitor of the tyrosine phosphatase PTPN22

scientific article published on 12 April 2019

Identification of HN252 as a potent inhibitor of protein phosphatase PPM1B

scientific article published on 13 October 2020

Lack of PDZD7 long isoform disrupts ankle-link complex and causes hearing loss in mice

scientific article published on 29 November 2019

Monitoring protein conformational changes and dynamics using stable-isotope labeling and mass spectrometry

scientific article published on 8 May 2014

Multiple ligand-specific conformations of the β2-adrenergic receptor

scientific article

Optimization of a peptide ligand for the adhesion GPCR ADGRG2 provides a potent tool to explore receptor biology

scientific article published on 10 December 2020

Structural studies of phosphorylation-dependent interactions between the V2R receptor and arrestin-2

scientific article published on 22 April 2021

The role of G protein-coupled receptors in cochlear planar cell polarity.

scientific article published on 24 February 2016

Unsaturated bond recognition leads to biased signal in a fatty acid receptor

scientific article published on 02 March 2023

β-Arrestin-1 deficiency ameliorates renal interstitial fibrosis by blocking Wnt1/β-catenin signaling in mice

scientific article published on 7 November 2017

β-Arrestins promote podocyte injury by inhibition of autophagy in diabetic nephropathy.

scientific article published on 7 April 2016

List of works by Jinpeng Sun

Ablation of somatostatin cells leads to impaired pancreatic islet function and neonatal death in rodents.

Allosteric mechanisms underlie GPCR signaling to SH3-domain proteins through arrestin

Allosteric modulation of the catalytic VYD loop in Slingshot by its N-terminal domain underlies both Slingshot auto-inhibition and activation

Combinatorial inhibition of PTPN12-regulated receptors leads to a broadly effective therapeutic strategy in triple-negative breast cancer.

Computational strategy for bound state structure prediction in structure-based virtual screening: a case study of protein tyrosine phosphatase receptor type O inhibitors

Correction: Allosteric modulation of the catalytic VYD loop in Slingshot by its N-terminal domain underlies both Slingshot auto-inhibition and activation

Crystal structure and catalytic activity of the PPM1K N94K mutant

DeSiphering receptor core-induced and ligand-dependent conformational changes in arrestin via genetic encoded trimethylsilyl 1H-NMR probe

Differences in the H2S-induced quantal release of catecholamine in adrenal chromaffin cells of neonatal and adult rats

Discovery of novel FFA4 (GPR120) receptor agonists with β-arrestin2-biased characteristics.

Elevation of JAML Promotes Diabetic Kidney Disease by Modulating Podocyte Lipid Metabolism

Function and therapeutic potential of GPCRs in epididymis

Genetically Encoded Fluorescent Amino Acid for Monitoring Protein Interactions through FRET

Global phosphorylation analysis of beta-arrestin-mediated signaling downstream of a seven transmembrane receptor (7TMR).

Gpr97 Exacerbates AKI by Mediating Sema3A Signaling

Gq activity- and β-arrestin-1 scaffolding-mediated ADGRG2/CFTR coupling are required for male fertility.

H2S induces catecholamine secretion in rat adrenal chromaffin cells

Identification and structure-function analyses of an allosteric inhibitor of the tyrosine phosphatase PTPN22

Identification of HN252 as a potent inhibitor of protein phosphatase PPM1B

Lack of PDZD7 long isoform disrupts ankle-link complex and causes hearing loss in mice

Monitoring protein conformational changes and dynamics using stable-isotope labeling and mass spectrometry

Multiple ligand-specific conformations of the β2-adrenergic receptor

Optimization of a peptide ligand for the adhesion GPCR ADGRG2 provides a potent tool to explore receptor biology

Structural studies of phosphorylation-dependent interactions between the V2R receptor and arrestin-2

The role of G protein-coupled receptors in cochlear planar cell polarity.

Unsaturated bond recognition leads to biased signal in a fatty acid receptor

β-Arrestin-1 deficiency ameliorates renal interstitial fibrosis by blocking Wnt1/β-catenin signaling in mice

β-Arrestins promote podocyte injury by inhibition of autophagy in diabetic nephropathy.