List of works - Xin Lai

A gene regulatory architecture that controls region-independent dynamics of oligodendrocyte differentiation

scientific article published on 07 February 2019

A multi-level model accounting for the effects of JAK2-STAT5 signal modulation in erythropoiesis

scientific article published on 9 July 2009

A new semisynthetic cardenolide analog 3β-[2-(1-amantadine)- 1-on-ethylamine]-digitoxigenin (AMANTADIG) affects G2/M cell cycle arrest and miRNA expression profiles and enhances proapoptotic survivin-2B expression in renal cell carcinoma cell lines.

scientific article published on 14 January 2017

A systems' biology approach to study microRNA-mediated gene regulatory networks

scientific article (publication date: 2013)

Artificial intelligence in cancer target identification and drug discovery

publication published on 10 May 2022

Asthma phenotyping, therapy, and prevention: what can we learn from systems biology?

scientific article published on 11 January 2013

Bacterial Adherence and Dwelling Probability: Two Drivers of Early Alveolar Infection by Streptococcus pneumoniae Identified in Multi-Level Mathematical Modeling.

scientific article published on 15 May 2018

Computational analysis and modeling the effectiveness of 'Zanamivir' targeting neuraminidase protein in pandemic H1N1 strains

scientific article

Computational analysis of target hub gene repression regulated by multiple and cooperative miRNAs

scientific article published on 13 July 2012

Cooperative gene regulation by microRNA pairs and their identification using a computational workflow

scientific article published on 29 May 2014

Corrigendum: Multiplicity of Mathematical Modeling Strategies to Search for Molecular and Cellular Insights into Bacteria Lung Infection.

scientific article published on 30 October 2017

Exosomal lncRNAs and cancer: connecting the missing links

scientific article published on 01 January 2019

Innate extracellular vesicles from melanoma patients suppress β-catenin in tumor cells by miRNA-34a

scientific article published on 07 March 2019

Integration of sensitivity and bifurcation analysis to detect critical processes in a model combining signalling and cell population dynamics

article

Kinetic modeling-based detection of genetic signatures that provide chemoresistance via the E2F1-p73/DNp73-miR-205 network

scientific article published on 27 February 2013

MiR-205-5p and miR-342-3p cooperate in the repression of the E2F1 transcription factor in the context of anticancer chemotherapy resistance.

scientific article published in January 2018

MicroRNA-Regulated Networks: The Perfect Storm for Classical Molecular Biology, the Ideal Scenario for Systems Biology ⬇️

scientific article published on January 1, 2013

Model-based genotype-phenotype mapping used to investigate gene signatures of immune sensitivity and resistance in melanoma micrometastasis

scientific article published on 26 April 2016

Model-based investigation of the transcriptional activity of p53 and its feedback loop regulation via 14-3-3σ.

scientific article published in September 2011

Modeling miRNA Regulation in Cancer Signaling Systems: miR-34a Regulation of the p53/Sirt1 Signaling Module ⬇️

scientific article published on January 1, 2012

Multiplicity of Mathematical Modeling Strategies to Search for Molecular and Cellular Insights into Bacteria Lung Infection.

scientific article published on 30 August 2017

Network- and systems-based re-engineering of dendritic cells with non-coding RNAs for cancer immunotherapy

scientific article published on 01 January 2021

RNA Sequencing of Collecting Duct Renal Cell Carcinoma Suggests an Interaction between miRNA and Target Genes and a Predominance of Deregulated Solute Carrier Genes

scientific article published on 24 December 2019

Serum levels of miR-320 family members are associated with clinical parameters and diagnosis in prostate cancer patients.

scientific article published on 30 December 2017

Systems Medicine for Lung Diseases: Phenotypes and Precision Medicine in Cancer, Infection, and Allergy

scientific article published on January 2016

Systems biology-based investigation of cooperating microRNAs as monotherapy or adjuvant therapy in cancer

scientific article published on 01 September 2019

THP-1-derived macrophages render lung epithelial cells hypo-responsive to Legionella pneumophila - a systems biology study.

scientific article published on 20 September 2017

Third-Kind Encounters in Biomedicine: Immunology Meets Mathematics and Informatics to Become Quantitative and Predictive.