List of works - Penella Woll

A Phase II Nonrandomised Open-Label Study of Liposomal Daunorubicin (DaunoXome) in Advanced Soft Tissue Sarcoma.

scientific article

A neuropeptide antagonist that inhibits the growth of small cell lung cancer in vitro ⬇️

scientific article published on July 1, 1990

A phase I and pharmacokinetic study of ixabepilone in combination with Carboplatin in patients with advanced solid malignancies.

scientific article

A phase I study of intravenous bryostatin 1 in patients with advanced cancer

scientific article

A phase I trial of amsalog (CI-921) administered by intravenous infusion using a 5-day schedule.

scientific article

A splice variant of the neuron-restrictive silencer factor repressor is expressed in small cell lung cancer: a potential role in derepression of neuroendocrine genes and a useful clinical marker

scientific article (publication date: April 2000)

A study of amsalog (CI-921) administered orally on a 5-day schedule, with bioavailability and pharmacokinetically guided dose escalation.

scientific article published in January 2002

Adjuvant chemotherapy with doxorubicin, ifosfamide, and lenograstim for resected soft-tissue sarcoma (EORTC 62931): a multicentre randomised controlled trial.

scientific article

Analysis of circulating angiogenic biomarkers from patients in two phase III trials in lung cancer of chemotherapy alone or chemotherapy and thalidomide ⬇️

scientific article published on February 21, 2012

Angiogenic growth factor expression in benign and malignant vascular tumours

scientific article published on 28 June 2014

Angiosarcoma

scientific article published on 25 May 2010

Anti-angiogenic therapies for the treatment of angiosarcoma: a clinical update

scientific article published on 7 November 2017

Anti-angiogenic therapy using thalidomide combined with chemotherapy in small cell lung cancer: a randomized, double-blind, placebo-controlled trial.

scientific article published on 16 July 2009

Arginine vasopressin promoter regulation is mediated by a neuron-restrictive silencer element in small cell lung cancer

scientific article published on 01 October 1999

Associated Links Among Smoking, Chronic Obstructive Pulmonary Disease, and Small Cell Lung Cancer: A Pooled Analysis in the International Lung Cancer Consortium

scientific article published on 24 September 2015

Association analysis of driver-gene related genetic variants identified novel lung cancer susceptibility loci with 20,871 lung cancer cases and 15,971 controls

scientific article published on 10 April 2020

Back pain and testicular germ cell tumours

scientific article published on 01 April 1987

Bone-targeted agents in the treatment of lung cancer.

scientific article published on July 2015

Breast milk in Botswana: cream and vitamin C contents ⬇️

scientific article published on June 1, 1982

CHRNA5 risk variant predicts delayed smoking cessation and earlier lung cancer diagnosis--a meta-analysis

scientific article published in May 2015

Can cytotoxic dose-intensity be increased by using granulocyte colony-stimulating factor? A randomized controlled trial of lenograstim in small-cell lung cancer

scientific article published on 01 March 1995

Cannabis smoking and lung cancer risk: Pooled analysis in the International Lung Cancer Consortium

scientific article published on 30 June 2014

Carboplatin versus two doses of cisplatin in combination with gemcitabine in the treatment of advanced non-small-cell lung cancer: Results from a British Thoracic Oncology Group randomised phase III trial

scientific article

Concurrent once-daily versus twice-daily chemoradiotherapy in patients with limited-stage small-cell lung cancer (CONVERT): an open-label, phase 3, randomised, superiority trial ⬇️

scientific article published on 19 June 2017

Cytokine Therapy

Cytotoxic dose-response relationships in small cell lung cancer ⬇️

scientific article published on July 1, 1997

Delaying skeletal-related events in a randomized phase 3 study of denosumab versus zoledronic acid in patients with advanced cancer: an analysis of data from patients with solid tumors

scientific article

Detection of small cell lung cancer by RT-PCR for neuropeptides, neuropeptide receptors, or a splice variant of the neuron restrictive silencer factor

scientific article published on 01 January 2003

Dose intensity in small cell lung cancer.

scientific article published on April 1998

Effects of COX-2 inhibition on expression of vascular endothelial growth factor and interleukin-8 in lung cancer cells

scientific article

Effects of erythropoietin on mobilisation of haemopoietic progenitor cells

scientific article published on 01 July 1994

Effects of granulocyte-macrophage colony-stimulating factor and dose intensification of V-ICE chemotherapy in small-cell lung cancer: a prospective randomized study of 300 patients ⬇️

scientific article published on February 1, 1998

Elevated platelet count appears to be causally associated with increased risk of lung cancer: A Mendelian randomization analysis

scientific article published on 30 January 2019

Eribulin in soft-tissue sarcoma

scientific article published on 10 February 2016

Establishment and molecular characterisation of seven novel soft-tissue sarcoma cell lines.

scientific article published on 25 August 2016

Fine mapping of MHC region in lung cancer highlights independent susceptibility loci by ethnicity

scientific article published in Nature Communications

First-line anthracycline-based chemotherapy for angiosarcoma and other soft tissue sarcoma subtypes: pooled analysis of eleven European Organisation for Research and Treatment of Cancer Soft Tissue and Bone Sarcoma Group trials.

scientific article published on December 2014

First-line erlotinib in patients with advanced non-small-cell lung cancer unsuitable for chemotherapy (TOPICAL): a double-blind, placebo-controlled, phase 3 trial

scientific article

Further investigation of the role of HLA-DPB1 in adult Hodgkin's disease (HD) suggests an influence on susceptibility to different HD subtypes

scientific article published on July 1999

Ganetespib in combination with pemetrexed-platinum chemotherapy in patients with pleural Mesothelioma (MESO-02): A phase Ib trial

scientific article published on 15 July 2020

Gemcitabine and docetaxel versus doxorubicin as first-line treatment in previously untreated advanced unresectable or metastatic soft-tissue sarcomas (GeDDiS): a randomised controlled phase 3 trial

scientific article published on 4 September 2017

Genetic Risk Can Be Decreased: Quitting Smoking Decreases and Delays Lung Cancer for Smokers With High and Low CHRNA5 Risk Genotypes - A Meta-Analysis

scientific article published on 10 August 2016

Genetic interaction analysis among oncogenesis-related genes revealed novel genes and networks in lung cancer development

Genome-wide interaction study of smoking behavior and non-small cell lung cancer risk in Caucasian population

scientific article published on 20 October 2017

Genomic tests: unreliable for cancer? A focus on circulating DNA and lung cancer

scientific article published on 01 November 2007

Growth factors, antagonists and lung cancer

scientific article published on 01 November 1993

Guidelines for time-to-event end point definitions in sarcomas and gastrointestinal stromal tumors (GIST) trials: results of the DATECAN initiative (Definition for the Assessment of Time-to-event Endpoints in CANcer trials)†.

scientific article

Identification of susceptibility pathways for the role of chromosome 15q25.1 in modifying lung cancer risk

scientific article published in Nature Communications

Increased risk of lung cancer in individuals with a family history of the disease: a pooled analysis from the International Lung Cancer Consortium

scientific article

Lactate elimination in man: effects of lactate concentration and hepatic dysfunction ⬇️

scientific article

Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes

scientific article published on 12 June 2017

Lung cancer as the presenting feature of AIDS

scientific article published on 01 July 2001

Maintenance pazopanib versus placebo in Non-Small Cell Lung Cancer patients non-progressive after first line chemotherapy: A double blind randomised phase III study of the lung cancer group, EORTC 08092 (EudraCT: 2010-018566-23, NCT01208064).

scientific article published on 11 June 2015

Multicyclic, dose-intensive chemotherapy supported by sequential reinfusion of hematopoietic progenitors in whole blood

scientific article published on 01 January 1995

Neuroendocrine phenotype of small cell lung cancer

scientific article

New perspectives in lung cancer. 2. Growth factors and lung cancer ⬇️

scientific article published on December 1, 1991

Obesity, metabolic factors and risk of different histological types of lung cancer: A Mendelian randomization study

scientific article published on 8 June 2017

Optimizing the yield and utility of circulating cell-free DNA from plasma and serum.

scientific article

Outcome and Biomarker Analysis from a Multicenter Phase 2 Study of Ipilimumab in Combination with Carboplatin and Etoposide as First-Line Therapy for Extensive-Stage SCLC.

scientific article published on 10 June 2016

Overall survival improvement in patients with lung cancer and bone metastases treated with denosumab versus zoledronic acid: subgroup analysis from a randomized phase 3 study

scientific article published on 01 December 2012

Overcoming CYP1A1/1A2 mediated induction of metabolism by escalating erlotinib dose in current smokers

scientific article published on 21 January 2009

Pegfilgrastim for peripheral CD34+ mobilization in patients with solid tumours

scientific article published on 26 January 2009

Pericardial effusion complicating breast cancer

scientific article published on 01 August 1987

Peripheral blood progenitor cell transplantation in lymphoma and leukemia using a single apheresis

scientific article published on 01 December 1993

Persistent back pain due to malignant lymphadenopathy

scientific article

Phase II study of liposomal muramyl tripeptide phosphatidylethanolamine (MTP/PE) in advanced soft tissue sarcomas of the adult. An EORTC Soft Tissue and Bone Sarcoma Group study

scientific article

Phase II study of nimustine in metastatic soft tissue sarcoma. European Organization for Research and Treatment of Cancer Soft Tissue and Bone Sarcoma Group

scientific article

Phase II trial of raltitrexed ('Tomudex') in advanced small-cell lung cancer ⬇️

scientific article published on January 1, 1997

Phase II trial of temozolomide in low-grade non-Hodgkin's lymphoma.

scientific article

Publisher Correction: Shared heritability and functional enrichment across six solid cancers

scientific article published on 23 September 2019

Quality of life, support and smoking in advanced lung cancer patients: a qualitative study.

scientific article published on 30 April 2014

Raised serum urea predicts for early death in small cell lung cancer.

scientific article

Randomized Phase III Trial of Standard Therapy Plus Low Molecular Weight Heparin in Patients With Lung Cancer: FRAGMATIC Trial.

scientific article published on 23 December 2015

Randomized comparison of progenitor-cell mobilization using chemotherapy, stem-cell factor, and filgrastim or chemotherapy plus filgrastim alone in patients with ovarian cancer ⬇️

scientific article published on August 1, 1998

Randomized double-blind placebo-controlled trial of thalidomide in combination with gemcitabine and Carboplatin in advanced non-small-cell lung cancer

scientific article published on 21 September 2009

Randomized phase II study of three doses of the integrin inhibitor cilengitide versus docetaxel as second-line treatment for patients with advanced non-small-cell lung cancer

scientific article published on 3 July 2012

Randomized phase III trial of dose-dense chemotherapy supported by whole-blood hematopoietic progenitors in better-prognosis small-cell lung cancer

scientific article published in May 2005

Randomized, double-blind study of denosumab versus zoledronic acid in the treatment of bone metastases in patients with advanced cancer (excluding breast and prostate cancer) or multiple myeloma.

scientific article published on 22 February 2011

Relative hypocalcaemia and muscle cramps in patients receiving imatinib for gastrointestinal stromal tumour.

scientific article published in January 2006

Roles for USF-2 in lung cancer proliferation and bronchial carcinogenesis.

scientific article published in June 2005

Shared heritability and functional enrichment across six solid cancers

scientific article published in Nature Communications

Shared heritability and functional enrichment across six solid cancers

Studies on the expression of endothelin, its receptor subtypes, and converting enzymes in lung cancer and in human bronchial epithelium

scientific article published on 01 April 2000

Suramin for breast and prostate cancer: A pilot study of intermittent short infusions without adaptive control

scientific article published on 01 September 1994

The impact of chemotherapy on survival of patients with extremity and trunk wall soft tissue sarcoma: revisiting the results of the EORTC-STBSG 62931 randomised trial

scientific article published on 25 January 2019

The relationship between smoking and quality of life in advanced lung cancer patients: a prospective longitudinal study.

scientific article published on 12 September 2015

The roles of HOXD10 in the development and progression of head and neck squamous cell carcinoma (HNSCC).

scientific article

The use of bisphosphonates in the management of bone involvement from solid tumours and haematological malignancies - a European survey

scientific article

Totally implantable vascular access for long term chemotherapy

scientific article published on 01 March 1986

Treatment of gastrointestinal stromal tumor: focus on imatinib mesylate.

scientific article

Treatment with the Chk1 inhibitor Gö6976 enhances cisplatin cytotoxicity in SCLC cells

scientific article

Unbiased Detection of Somatic Copy Number Aberrations in cfDNA of Lung Cancer Cases and High-Risk Controls with Low Coverage Whole Genome Sequencing

scientific article published on 01 January 2016

Upstream stimulatory factor activates the vasopressin promoter via multiple motifs, including a non-canonical E-box

scientific article

Urinary-derived monocyte-colony stimulating factor (P-100) following treatment with carboplatin and etoposide in small cell lung cancer (SCLC)

scientific article published on 01 December 1993

Use of RT-PCR to detect co-expression of neuropeptides and their receptors in lung cancer.

scientific article

Use of hematopoietic progenitors in whole blood to support dose-dense chemotherapy: a randomized phase II trial in small-cell lung cancer patients

scientific article

Vascular-targeted agents for the treatment of angiosarcoma

scientific article published on 20 November 2013

Viability of haemopoietic progenitors from whole blood, bone marrow and leukapheresis product: effects of storage media, temperature and time

scientific article published on 01 November 1994

Who treats cancer?

scientific article published on 01 January 1987

[D-Arg1,D-Phe5,D-Trp7,9,Leu11]substance P, a potent bombesin antagonist in murine Swiss 3T3 cells, inhibits the growth of human small cell lung cancer cells in vitro

scientific article

List of works by Penella Woll

A Phase II Nonrandomised Open-Label Study of Liposomal Daunorubicin (DaunoXome) in Advanced Soft Tissue Sarcoma.

A neuropeptide antagonist that inhibits the growth of small cell lung cancer in vitro ⬇️

A phase I and pharmacokinetic study of ixabepilone in combination with Carboplatin in patients with advanced solid malignancies.

A phase I study of intravenous bryostatin 1 in patients with advanced cancer

A phase I trial of amsalog (CI-921) administered by intravenous infusion using a 5-day schedule.

A splice variant of the neuron-restrictive silencer factor repressor is expressed in small cell lung cancer: a potential role in derepression of neuroendocrine genes and a useful clinical marker

A study of amsalog (CI-921) administered orally on a 5-day schedule, with bioavailability and pharmacokinetically guided dose escalation.

Adjuvant chemotherapy with doxorubicin, ifosfamide, and lenograstim for resected soft-tissue sarcoma (EORTC 62931): a multicentre randomised controlled trial.

Analysis of circulating angiogenic biomarkers from patients in two phase III trials in lung cancer of chemotherapy alone or chemotherapy and thalidomide ⬇️

Angiogenic growth factor expression in benign and malignant vascular tumours

Angiosarcoma

Anti-angiogenic therapies for the treatment of angiosarcoma: a clinical update

Anti-angiogenic therapy using thalidomide combined with chemotherapy in small cell lung cancer: a randomized, double-blind, placebo-controlled trial.

Arginine vasopressin promoter regulation is mediated by a neuron-restrictive silencer element in small cell lung cancer

Associated Links Among Smoking, Chronic Obstructive Pulmonary Disease, and Small Cell Lung Cancer: A Pooled Analysis in the International Lung Cancer Consortium

Association analysis of driver-gene related genetic variants identified novel lung cancer susceptibility loci with 20,871 lung cancer cases and 15,971 controls

Back pain and testicular germ cell tumours

Bone-targeted agents in the treatment of lung cancer.

Breast milk in Botswana: cream and vitamin C contents ⬇️

CHRNA5 risk variant predicts delayed smoking cessation and earlier lung cancer diagnosis--a meta-analysis

Can cytotoxic dose-intensity be increased by using granulocyte colony-stimulating factor? A randomized controlled trial of lenograstim in small-cell lung cancer

Cannabis smoking and lung cancer risk: Pooled analysis in the International Lung Cancer Consortium

Carboplatin versus two doses of cisplatin in combination with gemcitabine in the treatment of advanced non-small-cell lung cancer: Results from a British Thoracic Oncology Group randomised phase III trial

Concurrent once-daily versus twice-daily chemoradiotherapy in patients with limited-stage small-cell lung cancer (CONVERT): an open-label, phase 3, randomised, superiority trial ⬇️

Cytokine Therapy

Cytotoxic dose-response relationships in small cell lung cancer ⬇️

Delaying skeletal-related events in a randomized phase 3 study of denosumab versus zoledronic acid in patients with advanced cancer: an analysis of data from patients with solid tumors

Detection of small cell lung cancer by RT-PCR for neuropeptides, neuropeptide receptors, or a splice variant of the neuron restrictive silencer factor

Dose intensity in small cell lung cancer.

Effects of COX-2 inhibition on expression of vascular endothelial growth factor and interleukin-8 in lung cancer cells

Effects of erythropoietin on mobilisation of haemopoietic progenitor cells

Effects of granulocyte-macrophage colony-stimulating factor and dose intensification of V-ICE chemotherapy in small-cell lung cancer: a prospective randomized study of 300 patients ⬇️

Elevated platelet count appears to be causally associated with increased risk of lung cancer: A Mendelian randomization analysis

Eribulin in soft-tissue sarcoma

Establishment and molecular characterisation of seven novel soft-tissue sarcoma cell lines.

Fine mapping of MHC region in lung cancer highlights independent susceptibility loci by ethnicity

First-line anthracycline-based chemotherapy for angiosarcoma and other soft tissue sarcoma subtypes: pooled analysis of eleven European Organisation for Research and Treatment of Cancer Soft Tissue and Bone Sarcoma Group trials.

First-line erlotinib in patients with advanced non-small-cell lung cancer unsuitable for chemotherapy (TOPICAL): a double-blind, placebo-controlled, phase 3 trial

Further investigation of the role of HLA-DPB1 in adult Hodgkin's disease (HD) suggests an influence on susceptibility to different HD subtypes

Ganetespib in combination with pemetrexed-platinum chemotherapy in patients with pleural Mesothelioma (MESO-02): A phase Ib trial

Gemcitabine and docetaxel versus doxorubicin as first-line treatment in previously untreated advanced unresectable or metastatic soft-tissue sarcomas (GeDDiS): a randomised controlled phase 3 trial

Genetic Risk Can Be Decreased: Quitting Smoking Decreases and Delays Lung Cancer for Smokers With High and Low CHRNA5 Risk Genotypes - A Meta-Analysis

Genetic interaction analysis among oncogenesis-related genes revealed novel genes and networks in lung cancer development

Genome-wide interaction study of smoking behavior and non-small cell lung cancer risk in Caucasian population

Genomic tests: unreliable for cancer? A focus on circulating DNA and lung cancer

Growth factors, antagonists and lung cancer

Guidelines for time-to-event end point definitions in sarcomas and gastrointestinal stromal tumors (GIST) trials: results of the DATECAN initiative (Definition for the Assessment of Time-to-event Endpoints in CANcer trials)†.

Identification of susceptibility pathways for the role of chromosome 15q25.1 in modifying lung cancer risk

Increased risk of lung cancer in individuals with a family history of the disease: a pooled analysis from the International Lung Cancer Consortium

Lactate elimination in man: effects of lactate concentration and hepatic dysfunction ⬇️

Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes

Lung cancer as the presenting feature of AIDS

Maintenance pazopanib versus placebo in Non-Small Cell Lung Cancer patients non-progressive after first line chemotherapy: A double blind randomised phase III study of the lung cancer group, EORTC 08092 (EudraCT: 2010-018566-23, NCT01208064).

Multicyclic, dose-intensive chemotherapy supported by sequential reinfusion of hematopoietic progenitors in whole blood

Neuroendocrine phenotype of small cell lung cancer

New perspectives in lung cancer. 2. Growth factors and lung cancer ⬇️

Obesity, metabolic factors and risk of different histological types of lung cancer: A Mendelian randomization study

Optimizing the yield and utility of circulating cell-free DNA from plasma and serum.

Outcome and Biomarker Analysis from a Multicenter Phase 2 Study of Ipilimumab in Combination with Carboplatin and Etoposide as First-Line Therapy for Extensive-Stage SCLC.

Overall survival improvement in patients with lung cancer and bone metastases treated with denosumab versus zoledronic acid: subgroup analysis from a randomized phase 3 study

Overcoming CYP1A1/1A2 mediated induction of metabolism by escalating erlotinib dose in current smokers

Pegfilgrastim for peripheral CD34+ mobilization in patients with solid tumours

Pericardial effusion complicating breast cancer

Peripheral blood progenitor cell transplantation in lymphoma and leukemia using a single apheresis

Persistent back pain due to malignant lymphadenopathy

Phase II study of liposomal muramyl tripeptide phosphatidylethanolamine (MTP/PE) in advanced soft tissue sarcomas of the adult. An EORTC Soft Tissue and Bone Sarcoma Group study

Phase II study of nimustine in metastatic soft tissue sarcoma. European Organization for Research and Treatment of Cancer Soft Tissue and Bone Sarcoma Group

Phase II trial of raltitrexed ('Tomudex') in advanced small-cell lung cancer ⬇️

Phase II trial of temozolomide in low-grade non-Hodgkin's lymphoma.

Publisher Correction: Shared heritability and functional enrichment across six solid cancers

Quality of life, support and smoking in advanced lung cancer patients: a qualitative study.

Raised serum urea predicts for early death in small cell lung cancer.

Randomized Phase III Trial of Standard Therapy Plus Low Molecular Weight Heparin in Patients With Lung Cancer: FRAGMATIC Trial.

Randomized comparison of progenitor-cell mobilization using chemotherapy, stem-cell factor, and filgrastim or chemotherapy plus filgrastim alone in patients with ovarian cancer ⬇️

Randomized double-blind placebo-controlled trial of thalidomide in combination with gemcitabine and Carboplatin in advanced non-small-cell lung cancer

Randomized phase II study of three doses of the integrin inhibitor cilengitide versus docetaxel as second-line treatment for patients with advanced non-small-cell lung cancer

Randomized phase III trial of dose-dense chemotherapy supported by whole-blood hematopoietic progenitors in better-prognosis small-cell lung cancer

Randomized, double-blind study of denosumab versus zoledronic acid in the treatment of bone metastases in patients with advanced cancer (excluding breast and prostate cancer) or multiple myeloma.

Relative hypocalcaemia and muscle cramps in patients receiving imatinib for gastrointestinal stromal tumour.