List of works - Nigel Garrett

Ability to develop broadly neutralizing HIV-1 antibodies is not restricted by the germline Ig gene repertoire

scientific article published on 30 March 2015

Acceptability of Early Antiretroviral Therapy Among South African Women

scientific article published on 21 February 2017

Antibody Maturation in Women Who Acquire HIV Infection While Using Antiretroviral Preexposure Prophylaxis

scientific article

Assessing the safety and pharmacokinetics of the anti-HIV monoclonal antibody CAP256V2LS alone and in combination with VRC07-523LS and PGT121 in South African women: study protocol for the first-in-human CAPRISA 012B phase I clinical trial

scientific article published on 26 November 2020

Beyond syndromic management: Opportunities for diagnosis-based treatment of sexually transmitted infections in low- and middle-income countries.

scientific article published on 24 April 2018

Cervicovaginal Inflammation Facilitates Acquisition of Less Infectious HIV Variants

scientific article published on 29 September 2016

Challenges of diagnosing acute HIV-1 subtype C infection in African women: performance of a clinical algorithm and the need for point-of-care nucleic-acid based testing ⬇️

scientific article

Characterization of somatic cell nuclear reprogramming by oocytes in which a linker histone is required for pluripotency gene reactivation

scientific article

Clinic flow for STI, HIV, and TB patients in an urban infectious disease clinic offering point-of-care testing services in Durban, South Africa

scientific article

Clinic-Based Evaluation of a Point-of-Care Creatinine Assay to Screen for Renal Impairment Among HIV-Positive Patients Receiving Tenofovir Disoproxil Fumarate

scientific article published on 15 December 2017

Comparative cost analysis of point-of-care versus laboratory-based testing to initiate and monitor HIV treatment in South Africa

scientific article published on 16 October 2019

Comparison of the rate and size of HIV-1 viral load blips with Roche COBAS TaqMan HIV-1 versions 1.0 and 2.0 and implications for patient management ⬇️

scientific article published on January 18, 2012

Computational analysis of antibody dynamics identifies recent HIV-1 infection

scientific article published on 21 December 2017

Cooperation between Strain-Specific and Broadly Neutralizing Responses Limited Viral Escape and Prolonged the Exposure of the Broadly Neutralizing Epitope

scientific article published on 5 July 2017

Correction for Anthony et al., "Cooperation between Strain-Specific and Broadly Neutralizing Responses Limited Viral Escape and Prolonged the Exposure of the Broadly Neutralizing Epitope".

scientific article published on 13 April 2018

Developmental pathway for potent V1V2-directed HIV-neutralizing antibodies

scientific article

Diagnostic accuracy of the Xpert CT/NG and OSOM Trichomonas Rapid assays for point-of-care STI testing among young women in South Africa: a cross-sectional study

Dolutegravir for first-line antiretroviral therapy in low-income and middle-income countries: uncertainties and opportunities for implementation and research

article by Jienchi Dorward et al published July 2018 in The lancet. HIV

Dynamics of raltegravir resistance profile in an HIV type 2-infected patient.

scientific article published in August 2009

Early evolution of human leucocyte antigen-associated escape mutations in variable Gag proteins predicts CD4+ decline in HIV-1 subtype C-infected women

scientific article

Effect of Antiretroviral Therapy on the Memory and Activation Profiles of B Cells in HIV-Infected African Women

scientific article published on 30 December 2016

Efficacy and safety of tenofovir-containing antiretroviral therapy in women who acquired HIV while enrolled in tenofovir gel prophylaxis trials

scientific article published on 4 November 2016

Epigenetic stability of repressed states involving the histone variant macroH2A revealed by nuclear transfer to Xenopus oocytes

scientific article published in November 2011

Functional characterization of Vif proteins from HIV-1 infected patients with different APOBEC3G haplotypes

scientific article published on 08 April 2016

HIRA dependent H3.3 deposition is required for transcriptional reprogramming following nuclear transfer to Xenopus oocytes

scientific article published on 29 October 2012

HIV Superinfection Drives De Novo Antibody Responses and Not Neutralization Breadth

article

HIV disease progression in seroconvertors from the CAPRISA 004 tenofovir gel pre-exposure prophylaxis trial

scientific article

HIV treatment outcomes among people with initiation CD4 counts >500 cells/µL after implementation of Treat All in South African public clinics: a retrospective cohort study

scientific article published on 01 April 2020

HIV-specific Fc effector function early in infection predicts the development of broadly neutralizing antibodies.

scientific article published on 9 April 2018

HPV infection and the genital cytokine milieu in women at high risk of HIV acquisition

scientific article published on 19 November 2019

Health-related quality of life dynamics of HIV-positive South African women up to ART initiation: evidence from the CAPRISA 002 acute infection cohort study

scientific article

Histone variant macroH2A confers resistance to nuclear reprogramming ⬇️

scientific article

IgG3 enhances neutralization potency and Fc effector function of an HIV V2-specific broadly neutralizing antibody

scientific article published on 16 December 2019

Impact of an educational video as a consent tool on knowledge about cure research among patients and caregivers at HIV clinics in South Africa

scientific article published in April 2018

Impact of antiretroviral therapy on health-related quality of life among South African women in the CAPRISA 002 acute infection study

scientific article

Integrin α4β7 expression on peripheral blood CD4+ T cells predicts HIV acquisition and disease progression outcomes.

scientific article published in January 2018

Landscapes of binding antibody and T-cell responses to pox-protein HIV vaccines in Thais and South Africans

scientific article published on 30 January 2020

Low CD4 count and educational status predict abnormal cervical smears amongst HIV-positive women initiating antiretroviral therapy in South Africa

scientific article published on 30 March 2020

Modulation of Female Genital Tract-Derived Dendritic Cell Migration and Activation in Response to Inflammatory Cytokines and Toll-Like Receptor Agonists

scientific article

Multi-Donor Longitudinal Antibody Repertoire Sequencing Reveals the Existence of Public Antibody Clonotypes in HIV-1 Infection.

scientific article published on 31 May 2018

New Member of the V1V2-Directed CAP256-VRC26 Lineage That Shows Increased Breadth and Exceptional Potency

scientific article

Opportunities for earlier diagnosis of HIV in general practice

scientific article

Point-of-Care HIV Viral Load Testing: an Essential Tool for a Sustainable Global HIV/AIDS Response

scientific article published on 15 May 2019

Point-of-care viral load testing and differentiated HIV care

scientific article published in January 2018

Positive Selection at Key Residues in the HIV Envelope Distinguishes Broad and Strain-Specific Plasma Neutralizing Antibodies

article

Protocol for a randomised controlled implementation trial of point-of-care viral load testing and task shifting: the Simplifying HIV TREAtment and Monitoring (STREAM) study

scientific article published on 27 September 2017

Raltegravir treatment response in an HIV-2 infected patient: a case report

scientific article published in May 2008

Rapid disease progression in HIV-1 subtype C-infected South African women

scientific article

Replication Capacity of Viruses from Acute Infection Drives HIV-1 Disease Progression

scientific article published on February 2017

Risk Factors for HIV Acquisition in High Risk Women in a Generalised Epidemic Setting

scientific article published in July 2015

South African HIV-1 subtype C transmitted variants with a specific V2 motif show higher dependence on α4β7 for replication

scientific article published on 24 June 2015

Targeted screening of at-risk adults for acute HIV-1 infection in sub-Saharan Africa

scientific article

The Recent Infection Testing Algorithm (RITA) in clinical practice: a survey of HIV clinicians in England and Northern Ireland ⬇️

scientific article published on March 14, 2012

The Replication-Competent HIV-1 Latent Reservoir is Primarily Established Near the Time of Therapy Initiation: Supplemental Material for Abrahams et al

article

The replication-competent HIV-1 latent reservoir is primarily established near the time of therapy initiation

scientific article published on 01 October 2019

Tpt1 activates transcription of oct4 and nanog in transplanted somatic nuclei

scientific article published on 19 April 2007

Understanding how community antiretroviral delivery influences engagement in HIV care: a qualitative assessment of the Centralised Chronic Medication Dispensing and Distribution programme in South Africa

scientific article published on 15 May 2020

V2-Directed Vaccine-like Antibodies from HIV-1 Infection Identify an Additional K169-Binding Light Chain Motif with Broad ADCC Activity

article

Viral variants that initiate and drive maturation of V1V2-directed HIV-1 broadly neutralizing antibodies

scientific article

Widespread transcription in an amphibian oocyte relates to its reprogramming activity on transplanted somatic nuclei

scientific article published on 15 June 2011

List of works by Nigel Garrett

Ability to develop broadly neutralizing HIV-1 antibodies is not restricted by the germline Ig gene repertoire

Acceptability of Early Antiretroviral Therapy Among South African Women

Antibody Maturation in Women Who Acquire HIV Infection While Using Antiretroviral Preexposure Prophylaxis

Assessing the safety and pharmacokinetics of the anti-HIV monoclonal antibody CAP256V2LS alone and in combination with VRC07-523LS and PGT121 in South African women: study protocol for the first-in-human CAPRISA 012B phase I clinical trial

Beyond syndromic management: Opportunities for diagnosis-based treatment of sexually transmitted infections in low- and middle-income countries.

Cervicovaginal Inflammation Facilitates Acquisition of Less Infectious HIV Variants

Challenges of diagnosing acute HIV-1 subtype C infection in African women: performance of a clinical algorithm and the need for point-of-care nucleic-acid based testing ⬇️

Characterization of somatic cell nuclear reprogramming by oocytes in which a linker histone is required for pluripotency gene reactivation

Clinic flow for STI, HIV, and TB patients in an urban infectious disease clinic offering point-of-care testing services in Durban, South Africa

Clinic-Based Evaluation of a Point-of-Care Creatinine Assay to Screen for Renal Impairment Among HIV-Positive Patients Receiving Tenofovir Disoproxil Fumarate

Comparative cost analysis of point-of-care versus laboratory-based testing to initiate and monitor HIV treatment in South Africa

Comparison of the rate and size of HIV-1 viral load blips with Roche COBAS TaqMan HIV-1 versions 1.0 and 2.0 and implications for patient management ⬇️

Computational analysis of antibody dynamics identifies recent HIV-1 infection

Cooperation between Strain-Specific and Broadly Neutralizing Responses Limited Viral Escape and Prolonged the Exposure of the Broadly Neutralizing Epitope

Correction for Anthony et al., "Cooperation between Strain-Specific and Broadly Neutralizing Responses Limited Viral Escape and Prolonged the Exposure of the Broadly Neutralizing Epitope".

Developmental pathway for potent V1V2-directed HIV-neutralizing antibodies

Diagnostic accuracy of the Xpert CT/NG and OSOM Trichomonas Rapid assays for point-of-care STI testing among young women in South Africa: a cross-sectional study

Dolutegravir for first-line antiretroviral therapy in low-income and middle-income countries: uncertainties and opportunities for implementation and research

Dynamics of raltegravir resistance profile in an HIV type 2-infected patient.

Early evolution of human leucocyte antigen-associated escape mutations in variable Gag proteins predicts CD4+ decline in HIV-1 subtype C-infected women

Effect of Antiretroviral Therapy on the Memory and Activation Profiles of B Cells in HIV-Infected African Women

Efficacy and safety of tenofovir-containing antiretroviral therapy in women who acquired HIV while enrolled in tenofovir gel prophylaxis trials

Epigenetic stability of repressed states involving the histone variant macroH2A revealed by nuclear transfer to Xenopus oocytes

Functional characterization of Vif proteins from HIV-1 infected patients with different APOBEC3G haplotypes

HIRA dependent H3.3 deposition is required for transcriptional reprogramming following nuclear transfer to Xenopus oocytes

HIV Superinfection Drives De Novo Antibody Responses and Not Neutralization Breadth

HIV disease progression in seroconvertors from the CAPRISA 004 tenofovir gel pre-exposure prophylaxis trial

HIV treatment outcomes among people with initiation CD4 counts >500 cells/µL after implementation of Treat All in South African public clinics: a retrospective cohort study

HIV-specific Fc effector function early in infection predicts the development of broadly neutralizing antibodies.

HPV infection and the genital cytokine milieu in women at high risk of HIV acquisition

Health-related quality of life dynamics of HIV-positive South African women up to ART initiation: evidence from the CAPRISA 002 acute infection cohort study

Histone variant macroH2A confers resistance to nuclear reprogramming ⬇️

IgG3 enhances neutralization potency and Fc effector function of an HIV V2-specific broadly neutralizing antibody

Impact of an educational video as a consent tool on knowledge about cure research among patients and caregivers at HIV clinics in South Africa

Impact of antiretroviral therapy on health-related quality of life among South African women in the CAPRISA 002 acute infection study

Integrin α4β7 expression on peripheral blood CD4+ T cells predicts HIV acquisition and disease progression outcomes.

Landscapes of binding antibody and T-cell responses to pox-protein HIV vaccines in Thais and South Africans

Low CD4 count and educational status predict abnormal cervical smears amongst HIV-positive women initiating antiretroviral therapy in South Africa

Modulation of Female Genital Tract-Derived Dendritic Cell Migration and Activation in Response to Inflammatory Cytokines and Toll-Like Receptor Agonists

Multi-Donor Longitudinal Antibody Repertoire Sequencing Reveals the Existence of Public Antibody Clonotypes in HIV-1 Infection.

New Member of the V1V2-Directed CAP256-VRC26 Lineage That Shows Increased Breadth and Exceptional Potency

Opportunities for earlier diagnosis of HIV in general practice

Point-of-Care HIV Viral Load Testing: an Essential Tool for a Sustainable Global HIV/AIDS Response

Point-of-care viral load testing and differentiated HIV care

Positive Selection at Key Residues in the HIV Envelope Distinguishes Broad and Strain-Specific Plasma Neutralizing Antibodies

Protocol for a randomised controlled implementation trial of point-of-care viral load testing and task shifting: the Simplifying HIV TREAtment and Monitoring (STREAM) study

Raltegravir treatment response in an HIV-2 infected patient: a case report

Rapid disease progression in HIV-1 subtype C-infected South African women

Replication Capacity of Viruses from Acute Infection Drives HIV-1 Disease Progression

Risk Factors for HIV Acquisition in High Risk Women in a Generalised Epidemic Setting

South African HIV-1 subtype C transmitted variants with a specific V2 motif show higher dependence on α4β7 for replication

Targeted screening of at-risk adults for acute HIV-1 infection in sub-Saharan Africa

The Recent Infection Testing Algorithm (RITA) in clinical practice: a survey of HIV clinicians in England and Northern Ireland ⬇️

The Replication-Competent HIV-1 Latent Reservoir is Primarily Established Near the Time of Therapy Initiation: Supplemental Material for Abrahams et al

The replication-competent HIV-1 latent reservoir is primarily established near the time of therapy initiation

Tpt1 activates transcription of oct4 and nanog in transplanted somatic nuclei

Understanding how community antiretroviral delivery influences engagement in HIV care: a qualitative assessment of the Centralised Chronic Medication Dispensing and Distribution programme in South Africa

V2-Directed Vaccine-like Antibodies from HIV-1 Infection Identify an Additional K169-Binding Light Chain Motif with Broad ADCC Activity

Viral variants that initiate and drive maturation of V1V2-directed HIV-1 broadly neutralizing antibodies

Widespread transcription in an amphibian oocyte relates to its reprogramming activity on transplanted somatic nuclei