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List of works by Carl D Richards

A model of inflammatory arthritis highlights a role for oncostatin M in pro-inflammatory cytokine-induced bone destruction via RANK/RANKL

scientific article

A mouse model of airway disease: oncostatin M-induced pulmonary eosinophilia, goblet cell hyperplasia, and airway hyperresponsiveness are STAT6 dependent, and interstitial pulmonary fibrosis is STAT6 independent

scientific article published on 15 December 2010

Adenoviral transfer of murine OncostatinM induces inflammation and bone apposition in joints of IL-1, IL-6 and TNF-α deficient mice.

scientific article published on 4 February 2002

Adenoviral transfer of murine oncostatin M elicits periosteal bone apposition in knee joints of mice, despite synovial inflammation and up-regulated expression of interleukin-6 and receptor activator of nuclear factor-kappa B ligand

scientific article published on May 2002

Adenoviral transfer of the murine oncostatin M gene suppresses dextran-sodium sulfate-induced colitis

article

Adenoviral vector-mediated overexpression of IL-4 in the knee joint of mice with collagen-induced arthritis prevents cartilage destruction.

scientific article published in October 1999

Adenovirus vector expressing mouse oncostatin M induces acute-phase proteins and TIMP-1 expression in vivo in mice.

scientific article

Antibodies to rat soluble IL-6 receptor stimulate B9 hybridoma cell proliferation.

scientific article published on May 1997

Bronchial myofibroblasts and tissue remodelling in asthma

scientific article published on January 1, 1998

CD8+ T-cell-mediated suppression of HIV-1 long terminal repeat-driven gene expression is not modulated by the CC chemokines RANTES, macrophage inflammatory protein (MIP)-1 alpha and MIP-1 beta

scientific article published on 01 April 1997

Characterization of Proliferating Lesion-Resident Cells During All Stages of Atherosclerotic Growth

scientific article published on 15 August 2016

Construction of recombinant human type 5 adenoviruses expressing rodent IL-6 genes. An approach to investigate in vivo cytokine function.

scientific article

Cytokines oncostatin M and interleukin 1 regulate the expression of the IL-6 receptor (gp80, gp130).

scientific article published on August 1995

Direct anti-cancer effect of oncostatin M on chondrosarcoma.

scientific article published on 6 January 2011

Fc receptors for IgA and other immunoglobulins on resident and activated alveolar macrophages

scientific article published on 01 September 1983

Genetic partitioning of interleukin-6 signalling in mice dissociates Stat3 from Smad3-mediated lung fibrosis

scientific article

Growth plate damage, a feature of juvenile idiopathic arthritis, can be induced by adenoviral gene transfer of oncostatin M: a comparative study in gene-deficient mice

article

IL-15 can signal via IL-15Rα, JNK, and NF-κB to drive RANTES production by myeloid cells

scientific article published on 23 March 2012

IL-18/IL-15/IL-12 synergy induces elevated and prolonged IFN-γ production by ex vivo expanded NK cells which is not due to enhanced STAT4 activation.

scientific article published on 20 June 2017

IL-33 Mediates Lung Inflammation by the IL-6-Type Cytokine Oncostatin M

scientific article published on 28 November 2020

IL-6 mediates ER expansion during hyperpolarization of alternatively activated macrophages

article

IL6 and the acute phase reaction

scientific article published on September 1, 1992

IgA-mediated phagocytosis by mouse alveolar macrophages

scientific article published in July 1985

Immunomodulatory properties of diazepam-binding inhibitor: effect on human interleukin-6 secretion, lymphocyte proliferation and natural killer cell activity in vitro

scientific article published on 01 September 1993

In vivo initiation of unstimulated in vitro interleukin-1 release by alveolar macrophages

scientific article published on 01 March 1985

Increased expression of activated matrix metalloproteinase-2 by human endothelial cells after sublethal H2O2 exposure

scientific article published on 01 November 1997

Induction of osteogenesis in mesenchymal stem cells by activated monocytes/macrophages depends on oncostatin M signaling

scientific article

Injury measurement properties of serum interleukin-6 following lumbar decompression surgery.

scientific article

Innate Immune Cytokines, Fibroblast Phenotypes, and Regulation of Extracellular Matrix in Lung.

scientific article published on 24 January 2017

Interaction among hepatocyte-stimulating factors, interleukin 1, and glucocorticoids for regulation of acute phase plasma proteins in human hepatoma (HepG2) cells.

scientific article published on December 1987

Interferon beta 2/B-cell stimulatory factor type 2 shares identity with monocyte-derived hepatocyte-stimulating factor and regulates the major acute phase protein response in liver cells

scientific article

Interleukin-15 Contributes to the Regulation of Murine Adipose Tissue and Human Adipocytes

scientific article published on 17 December 2009

Interleukin-15 modulates adipose tissue by altering mitochondrial mass and activity.

scientific article

Interleukins 4 and 13 increase intestinal epithelial permeability by a phosphatidylinositol 3-kinase pathway. Lack of evidence for STAT 6 involvement.

scientific article published on September 2000

Local interleukin-12 gene transfer promotes conversion of an acute arthritis to a chronic destructive arthritis.

scientific article published in May 2002

Mainstream cigarette smoke exposure attenuates airway immune inflammatory responses to surrogate and common environmental allergens in mice, despite evidence of increased systemic sensitization

scientific article published on 01 September 2005

Matrix catabolism in arthritis: priming the guns with oncostatin M

scientific article published on 01 December 2004

Measurement of interleukin 6.

scientific article

Mitogen-activated protein kinases Erk1/2 and p38 are required for maximal regulation of TIMP-1 by oncostatin M in murine fibroblasts.

scientific article published on October 2004

Modulation of the anchorage-independent phenotype of human lung fibroblasts obtained from fibrotic tissue following culture with retinoid and corticosteroid.

scientific article published on March 1996

Multinucleate giant cells in murine and rat lungs during Nippostrongylus brasiliensis infections. A study of the kinetics of the response in vivo, cytochemistry, IgG- and C3-mediated functions.

scientific article

Murine cardiotrophin-1 stimulates the acute-phase response in rat hepatocytes and H35 hepatoma cells.

scientific article

Murine oncostatin M stimulates mouse synovial fibroblasts in vitro and induces inflammation and destruction in mouse joints in vivo.

scientific article published on October 2000

Neuroleptic malignant syndrome and the acute phase response.

scientific article published in August 2008

Novel function of Oncostatin M as a potent tumour-promoting agent in lung.

scientific article

Oncostatin M Stimulates c-Fos to Bind a Transcriptionally Responsive AP-1 Element within the Tissue Inhibitor of Metalloproteinase-1 Promoter

scientific article published in Journal of Biological Chemistry

Oncostatin M and TLR-4 ligand synergize to induce MCP-1, IL-6, and VEGF in human aortic adventitial fibroblasts and smooth muscle cells.

scientific article

Oncostatin M in combination with tumor necrosis factor alpha induces cartilage damage and matrix metalloproteinase expression in vitro and in vivo.

scientific article published in December 2003

Oncostatin M in the Regulation of Connective Tissue Cells and Macrophages in Pulmonary Disease

scientific article published on 05 December 2019

Oncostatin M induces IL-33 expression in liver endothelial cells in mice and expands ST2+CD4+ lymphocytes

scientific article published on 6 August 2015

Oncostatin M induction of eotaxin-1 expression requires the convergence of PI3'K and ERK1/2 MAPK signal transduction pathways.

scientific article

Oncostatin M inhibits IL-1-induced expression of IL-8 and granulocyte-macrophage colony-stimulating factor by synovial and lung fibroblasts

scientific article published on 01 January 1996

Oncostatin M overexpression induces matrix deposition, STAT3 activation, and SMAD1 Dysregulation in lungs of fibrosis-resistant BALB/c mice.

scientific article

Oncostatin M overexpression induces skin inflammation but is not required in the mouse model of imiquimod-induced psoriasis-like inflammation.

scientific article published on 12 May 2016

Oncostatin M regulates eotaxin expression in fibroblasts and eosinophilic inflammation in C57BL/6 mice.

scientific article published on January 2003

Oncostatin M regulates osteogenic differentiation of murine adipose-derived mesenchymal progenitor cells through a PKCdelta-dependent mechanism

scientific article published on 30 January 2015

Oncostatin M stimulates monocyte chemoattractant protein-1- and interleukin-1-induced matrix metalloproteinase-1 production by human synovial fibroblasts in vitro

scientific article published on 01 December 1997

Oncostatin M, but not interleukin-6 or leukemia inhibitory factor, stimulates expression of alpha1-proteinase inhibitor in A549 human alveolar epithelial cells.

scientific article published on June 1997

Oncostatin M-induced IL-6 expression in murine fibroblasts requires the activation of protein kinase Cdelta

scientific article published on 01 December 2006

Oncostatin-M up-regulates VCAM-1 and synergizes with IL-4 in eotaxin expression: involvement of STAT6.

scientific article published on April 2006

Overexpression of OSM and IL-6 impacts the polarization of pro-fibrotic macrophages and the development of bleomycin-induced lung fibrosis

scientific article published on 16 October 2017

Porcine Collagenase from Synovial Fibroblasts: cDNA Sequence and Modulation of Expression of RNA In Vitro by Various Cytokines ⬇️

scientific article published on June 1, 1991

Prostaglandin E2 enhances interleukin 8 (IL-8) and IL-6 but inhibits GMCSF production by IL-1 stimulated human synovial fibroblasts in vitro

scientific article published on 01 May 1996

Prostanoid enhancement of interleukin-6 production by rat peritoneal mast cells.

scientific article published on May 1995

Receptor subunit-specific action of oncostatin M in hepatic cells and its modulation by leukemia inhibitory factor

scientific article published on 01 August 2000

Recombinant oncostatin M stimulates the production of acute phase proteins in HepG2 cells and rat primary hepatocytes in vitro

scientific article published on 01 March 1992

Regulation of IL-17A responses in human airway smooth muscle cells by Oncostatin M.

scientific article

Regulation of IL-33 by Oncostatin M in Mouse Lung Epithelial Cells.

scientific article published on 15 September 2016

Regulation of IL-6 and the hepatic IL-6 receptor in acute inflammation in vivo

scientific article published on 01 January 1993

Regulation of tissue inhibitor of metalloproteinase-1 in fibroblasts and acute phase proteins in hepatocytes in vitro by mouse oncostatin M, cardiotrophin-1, and IL-6 ⬇️

scientific article published on September 1, 1997

Role of STAT6 and SMAD2 in a model of chronic allergen exposure: a mouse strain comparison study

scientific article published on 11 October 2008

Selective regulation of metalloproteinase inhibitor (TIMP-1) by oncostatin M in fibroblasts in culture

scientific article published on 01 June 1993

Separate roles of IL-6 and oncostatin M in mouse macrophage polarization in vitro and in vivo.

scientific article

Spontaneous in vitro release of alveolar-macrophage cytokines after the intratracheal instillation of bleomycin in rats. Characterization and kinetic studies

scientific article published on 01 May 1988

Stimulation of osteoclast differentiation in vitro by mouse oncostatin M, leukaemia inhibitory factor, cardiotrophin-1 and interleukin 6: synergy with dexamethasone.

scientific article

Superantigen immune stimulation activates epithelial STAT-1 and PI 3-K: PI 3-K regulation of permeability.

scientific article

Synergistic interactions of proinflammatory cytokines with oncostatin M: implications for joint destruction

Synoviocyte derived granulocyte macrophage colony stimulating factor mediates the survival of human lymphocytes

scientific article published on 01 July 1992

The enigmatic cytokine oncostatin m and roles in disease

scientific article published on 08 December 2013

The expression of matrix metalloproteinases and their inhibitors by pig synovial cells and their regulation by combinations of cytokines and growth factors

scientific article published on 01 November 1993

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