List of works by Steve Steinhubl

2017 Cardiovascular and Stroke Endpoint Definitions for Clinical Trials.

scientific article published in February 2018

2017 Cardiovascular and Stroke Endpoint Definitions for Clinical Trials.

scientific article published in March 2018

A brief review of the past and future of platelet P2Y12 antagonist

scientific article

A global view of atherothrombosis: baseline characteristics in the Clopidogrel for High Atherothrombotic Risk and Ischemic Stabilization, Management, and Avoidance (CHARISMA) trial

scientific article published in September 2005

A laboratory in your pocket

scientific article

A skin patch for sensing blood pressures

scientific article published on 01 September 2018

Absence of interaction between atorvastatin or other statins and clopidogrel: results from the interaction study

scientific article (publication date: 11 October 2004)

Adenosine diphosphate receptor blockade in coronary intervention

scientific article published on July 2004

An analysis of mortality rates with dual-antiplatelet therapy in the primary prevention population of the CHARISMA trial

scientific article (publication date: September 2007)

Analysis of risk of bleeding complications after different doses of aspirin in 192,036 patients enrolled in 31 randomized controlled trials

scientific article (publication date: 15 May 2005)

Antiplatelet effect of aspirin in patients with cerebrovascular disease

scientific article (publication date: June 2004)

Antiplatelet therapy in prevention of cardio- and venous thromboembolic events

scientific article published on April 2014

Antiplatelet therapy: aspirin

scientific article (publication date: March 2003)

Are antiplatelet effects of clopidogrel inhibited by atorvastatin? A research question formulated but not yet adequately tested

scientific article published in April 2003

Aspirin dose for the prevention of cardiovascular disease: a systematic review

scientific article (publication date: 9 May 2007)

Aspirin following PCI: too much of a good thing?

scientific article published on 17 March 2009

Aspirin to prevent cardiovascular disease: the association of aspirin dose and clopidogrel with thrombosis and bleeding

scientific article published in March 2009

Assessing platelet function during treatment with glycoprotein IIb/IIIa antagonists

scientific article

Atrial fibrillation in the setting of acute myocardial infarction--irregularly irregular treatment

scientific article published on 01 February 2008

Augmenting diagnostic vision with AI

Automatic identification of heart failure diagnostic criteria, using text analysis of clinical notes from electronic health records

scientific article published on 11 January 2013

Being successful at prevention: making it easy to do the right thing: comment on "Improving care after myocardial infarction using a 2-year internet-delivered intervention"

scientific article published on 01 November 2011

Bivalirudin, thrombin and platelets: clinical implications and future directions

scientific article published on August 2003

Bleeding complications with dual antiplatelet therapy among patients with stable vascular disease or risk factors for vascular disease: results from the Clopidogrel for High Atherothrombotic Risk and Ischemic Stabilization, Management, and Avoidance

scientific article

Bleeding events are associated with an increase in markers of inflammation in acute coronary syndromes: an ACUITY trial substudy

scientific article published on 01 February 2011

Bleeding risk associated with 1 year of dual antiplatelet therapy after percutaneous coronary intervention: Insights from the Clopidogrel for the Reduction of Events During Observation (CREDO) trial

scientific article published in November 2008

Bleeding, mortality, and antiplatelet therapy: results from the Clopidogrel for High Atherothrombotic Risk and Ischemic Stabilization, Management, and Avoidance (CHARISMA) trial

scientific article published in July 2011

Bleeding-associated outcomes with preoperative clopidogrel use in on- and off-pump coronary artery bypass

scientific article published on 01 July 2012

Can N-acetylcysteine reverse the antiplatelet effects of clopidogrel? An in vivo and vitro study

scientific article (publication date: October 2005)

Can mobile health technologies transform health care?

scientific article published in December 2013

Cardiovascular and nervous system changes during meditation

scientific article

Cardiovascular devices and platelet interactions: understanding the role of injury, flow, and cellular responses

scientific article published on April 2012

Characteristics of the modern-day physician house call

article by Shannon Fortin Ensign et al published February 2019 in Medicine

Characterizing Physicians Practice Phenotype from Unstructured Electronic Health Records

scientific article published on January 2016

Chronic kidney disease and undiagnosed atrial fibrillation in individuals with diabetes

scientific article published on 30 September 2020

Clinical outcomes according to permanent discontinuation of clopidogrel or placebo in the CHARISMA trial

scientific article published on 11 June 2009

Clinical outcomes of patients with diabetic nephropathy randomized to clopidogrel plus aspirin versus aspirin alone (a post hoc analysis of the clopidogrel for high atherothrombotic risk and ischemic stabilization, management, and avoidance [CHARISM

scientific article published in April 2009

Clopidogrel and aspirin versus aspirin alone for the prevention of atherothrombotic events

scientific article (publication date: 20 April 2006)

Clopidogrel bisulfate: in ST-segment elevation myocardial infarction: a viewpoint by Steven R Steinhubl

scientific article published on 01 January 2006

Clopidogrel for percutaneous coronary revascularization: time for more pretreatment, retreatment, or both?

scientific article

Clopidogrel treatment prior to percutaneous coronary intervention: when enough isn't enough

scientific article published on 13 March 2006

Clopidogrel's role in the management of atherosclerotic disease: a focus on acute coronary syndromes

scientific article (publication date: November 2003)

Clopidogrel-statin interaction: a mountain or a mole hill?

scientific article published on 01 August 2006

Clopidogrel: how good is it and how does it work?

scientific article (publication date: July 2004)

Comparative Effectiveness of Statin Therapy in Chronic Kidney Disease and Acute Myocardial Infarction: A Retrospective Cohort Study

scientific article

Comparison of long-term usefulness of clopidogrel therapy after the first percutaneous coronary intervention or coronary artery bypass grafting versus that after the second or repeat intervention

scientific article published in September 2004

Connected Health Technology for Cardiovascular Disease Prevention and Management

scientific article published on 18 May 2019

Considerable variability in platelet activity among patients with coronary artery disease in response to an increased maintenance dose of clopidogrel

scientific article

Current strategies in antiplatelet therapy--does identification of risk and adjustment of therapy contribute to more effective, personalized medicine in cardiovascular disease?

scientific article published on June 2010

Determination of the naturalhistory of aspirin resistance amongstable patients with cardiovascular disease

scientific article (publication date: October 2003)

Determining the efficacy of antiplatelet therapies for the individual: lessons from clinical trials

scientific article published in November 2007

Development and validation of a bleeding risk model for patients undergoing elective percutaneous coronary intervention.

scientific article published on 17 March 2010

Development of a Weight Loss Mobile App Linked With an Accelerometer for Use in the Clinic: Usability, Acceptability, and Early Testing of its Impact on the Patient-Doctor Relationship.

scientific article published on 31 March 2016

Development of a multi-institutional cohort to facilitate cardiovascular disease biomarker validation using existing biorepository samples linked to electronic health records

scientific article

Digital Medicine in Thyroidology: A New Era of Managing Thyroid Disease

scientific article published on 01 June 2019

Digital clinical trials: creating a vision for the future

scientific article published on 12 December 2019

Digital health care for older adults

scientific article published on 01 April 2019

Digital medical tools and sensors

scientific article published on January 2015

Digital medicine, on its way to being just plain medicine

scientific article published on 15 January 2018

Digital recruitment and enrollment in a remote nationwide trial of screening for undiagnosed atrial fibrillation: Lessons from the randomized, controlled mSToPS trial

Digitising the mind

scientific article published on 11 May 2017

Digitising the way to better sleep health

scientific article published on 14 February 2019

Digitizing clinical trials

scientific article published on 31 July 2020

Early Detection of Heart Failure Using Electronic Health Records: Practical Implications for Time Before Diagnosis, Data Diversity, Data Quantity, and Data Density

scientific article

Early and sustained dual oral antiplatelet therapy following percutaneous coronary intervention: a randomized controlled trial

scientific article (publication date: 20 November 2002)

Early coronary revascularization diminishes the risk of ischemic stroke with acute myocardial infarction

scientific article published on 7 September 2006

Early detection of heart failure with varying prediction windows by structured and unstructured data in electronic health records

scientific article

Effect of a Home-Based Wearable Continuous ECG Monitoring Patch on Detection of Undiagnosed Atrial Fibrillation: The mSToPS Randomized Clinical Trial

scientific article published on 01 July 2018

Effect of genetic variation in P2Y12 on TRAP-stimulated platelet response in healthy subjects

scientific article published on 01 October 2014

Effect of rimonabant on progression of atherosclerosis in patients with abdominal obesity and coronary artery disease: the STRADIVARIUS randomized controlled trial

scientific article published on April 2008

Effectiveness of 6 months of tailored text message reminders for obese male participants in a worksite weight loss program: randomized controlled trial.

scientific article

Effects of clopidogrel and aspirin combination versus aspirin alone on platelet aggregation and major receptor expression in patients with heart failure: the Plavix Use for Treatment Of Congestive Heart Failure (PLUTO-CHF) trial

scientific article (publication date: October 2003)

Effects of unfractionated heparin and glycoprotein IIb/IIIa antagonists versus bivalirdin on myeloperoxidase release from neutrophils

scientific article published on 24 May 2007

Efficacy and safety of clopidogrel pretreatment before percutaneous coronary intervention with and without glycoprotein IIb/IIIa inhibitor use.

scientific article published on 21 February 2008

Enoxaparin versus unfractionated heparin in elective percutaneous coronary intervention

scientific article published in September 2006

Enoxaparin versus unfractionated heparin in elective percutaneous coronary intervention 1-year results from the STEEPLE (SafeTy and efficacy of enoxaparin in percutaneous coronary intervention patients, an international randomized evaluation) trial

scientific article published in November 2009

Enoxaparin vs unfractionated heparin in high-risk patients with non-ST-segment elevation acute coronary syndromes managed with an intended early invasive strategy: primary results of the SYNERGY randomized trial

scientific article

Evaluation and management of thrombocytopenia and suspected heparin-induced thrombocytopenia in hospitalized patients: The Complications After Thrombocytopenia Caused by Heparin (CATCH) registry

scientific article

Expanding the Toolbox for Reversal of Anticoagulation in Chronic Kidney Disease

scientific article published on 01 October 2019

Figure Correction: How Consumers and Physicians View New Medical Technology: Comparative Survey

scientific article published on 18 December 2015

First-in-human experience of an antidote-controlled anticoagulant using RNA aptamer technology: a phase 1a pharmacodynamic evaluation of a drug-antidote pair for the controlled regulation of factor IXa activity

scientific article

Frequency of major noncardiac surgery and subsequent adverse events in the year after drug-eluting stent placement results from the EVENT (Evaluation of Drug-Eluting Stents and Ischemic Events) Registry

scientific article published in September 2010

G-protein-coupled receptors as signaling targets for antiplatelet therapy

scientific article

Glycoprotein IIb/IIIa receptor inhibitor-thrombolytic combination therapy for acute myocardial infarction

scientific article (publication date: July 2002)

Hematomas of at least 5 cm and outcomes in patients undergoing elective percutaneous coronary intervention: insights from the SafeTy and Efficacy of Enoxaparin in PCI patients, an internationaL randomized Evaluation (STEEPLE) trial

scientific article published in January 2010

Heparin-induced thrombocytopenia and cardiovascular diseases

scientific article

High-Definition Medicine

scientific article published on August 2017

High-sensitivity C-reactive protein and clopidogrel treatment in patients at high risk of cardiovascular events: a substudy from the CHARISMA trial

scientific article published on 10 March 2011

Historical observations on the discovery of platelets, platelet function testing and the first antiplatelet agent

scientific article

Home Monitoring of Blood Pressure: Short-Term Changes During Serial Measurements for 56398 Subjects

How Consumers and Physicians View New Medical Technology: Comparative Survey

scientific article

Identification of paroxysmal atrial fibrillation subtypes in over 13,000 individuals

scientific article published on 14 August 2018

Impact of Clopidogrel Therapy on Mortality and Cancer in Patients With Cardiovascular and Cerebrovascular Disease: A Patient-Level Meta-Analysis

scientific article published in January 2018

Impact of anticoagulation levels on outcomes in patients undergoing elective percutaneous coronary intervention: insights from the STEEPLE trial

scientific article

Impact of anticoagulation regimen prior to revascularization in patients with non-ST-segment elevation acute coronary syndromes: The ACUITY trial

scientific article published on 2 September 2015

Impact of anticoagulation regimens on sheath management and bleeding in patients undergoing elective percutaneous coronary intervention in the STEEPLE trial

scientific article published in February 2009

Impact of clopidogrel in patients with acute coronary syndromes requiring coronary artery bypass surgery: a multicenter analysis

scientific article

Impact of drug-eluting stents on outcomes of patients with end-stage renal disease undergoing percutaneous coronary revascularization

scientific article published in September 2006

Impact of genetic polymorphisms on clinical response to antithrombotics

scientific article

Impact of proton pump inhibitor therapy on the efficacy of clopidogrel in the CAPRIE and CREDO trials

scientific article

Implementation of mobile health tools--reply

scientific article published in April 2014

Incidence and clinical consequences of acquired thrombocytopenia after antithrombotic therapies in patients with acute coronary syndromes: results from the Acute Catheterization and Urgent Intervention Triage Strategy (ACUITY) trial

scientific article

Incidence and prevention of ischemic stroke following myocardial infarction: review of current literature

scientific article published on 3 August 2006

Incidence and prognostic significance of thrombocytopenia in patients treated with prolonged heparin therapy

scientific article

Incomplete inhibition of thromboxane biosynthesis by acetylsalicylic acid: determinants and effect on cardiovascular risk

scientific article published on 6 October 2008

Influence of timing of clopidogrel treatment on the efficacy and safety of bivalirudin in patients with non-ST-segment elevation acute coronary syndromes undergoing percutaneous coronary intervention: an analysis of the ACUITY (Acute Catheterization

scientific article

Influence of treatment duration with a 600-mg dose of clopidogrel before percutaneous coronary revascularization

scientific article published in December 2004

Inter- and intraindividual variability in daily resting heart rate and its associations with age, sex, sleep, BMI, and time of year: Retrospective, longitudinal cohort study of 92,457 adults

scientific article published on 05 February 2020

Interventions for Increasing Physical Activity: From "Ingenious Toys" to mHealth

scientific article published on 22 March 2016

Intravenous low-molecular-weight heparins compared with unfractionated heparin in percutaneous coronary intervention: quantitative review of randomized trials

scientific article published on December 2007

Inverse correlation between daily outdoor temperature and blood pressure in six US cities.

scientific article published on 19 April 2018

Is there a clinically significant interaction between calcium channel antagonists and clopidogrel?: results from the Clopidogrel for the Reduction of Events During Observation (CREDO) trial

scientific article

Lack of adverse clopidogrel-atorvastatin clinical interaction from secondary analysis of a randomized, placebo-controlled clopidogrel trial

scientific article (publication date: 26 August 2003)

Lack of evidence of a clopidogrel-statin interaction in the CHARISMA trial

scientific article (publication date: 24 July 2007)

Long data from the electrocardiogram

scientific article published on 01 June 2019

Low-molecular-weight heparins as adjunctive therapy to thrombolytics: extracting the best data

scientific article

Medication burden in patients with acute coronary syndromes

scientific article

Monitoring and Reversal of Anticoagulation and Antiplatelets

scientific article published on 09 July 2013

Monitoring of platelet function in the setting of glycoprotein IIb/IIIa inhibitor therapy

scientific article

Off the cuff: rebooting blood pressure treatment

scientific article

On the Effectiveness of Deep Representation Learning: the Atrial Fibrillation Case

scientific article published on 21 October 2019

Onset and offset of platelet inhibition after high-dose clopidogrel loading and standard daily therapy measured by a point-of-care assay in healthy volunteers.

scientific article published on 7 July 2006

Optimal timing for the initiation of pre-treatment with 300 mg clopidogrel before percutaneous coronary intervention

scientific article published on 9 February 2006

Optimizing antiplatelet therapy for the ACS patient: reacting to clinical trial data from the ISAR-REACT-2 studies

scientific article (publication date: 2006)

Oral antiplatelet therapy for percutaneous coronary revascularization

scientific article (publication date: April 2007)

Oral fluids that detect cardiovascular disease biomarkers

scientific article published on August 2012

Outcomes in adults with acute pulmonary embolism who are discharged from emergency departments: the Cardiovascular Research Network Venous Thromboembolism study

scientific article published on June 2015

PARAMO: a PARAllel predictive MOdeling platform for healthcare analytic research using electronic health records

scientific article

Patients with prior myocardial infarction, stroke, or symptomatic peripheral arterial disease in the CHARISMA trial

scientific article (publication date: 15 May 2007)

Percutaneous coronary interventions in patients with renal insufficiency: a high-risk, under-studied cohort

scientific article published on 01 August 2003

Pharmacodynamic interplay of the P2Y(1), P2Y(12), and TxA(2) pathways in platelets: the potential of triple antiplatelet therapy with P2Y(1) receptor antagonism

scientific article published on 12 December 2012

Pharmacokinetics and pharmacodynamics of a bolus and infusion of cangrelor: a direct, parenteral P2Y12 receptor antagonist

scientific article published on 24 September 2009

Phase 1b randomized study of antidote-controlled modulation of factor IXa activity in patients with stable coronary artery disease

scientific article published on 27 May 2008

Platelet activation and its patient-specific consequences

scientific article published on 22 October 2007

Platelet aggregation and its association with stent thrombosis and bleeding in clopidogrel-treated patients: initial evidence of a therapeutic window

scientific article published on July 2010

Platelet function monitoring in patients with coronary artery disease

scientific article published on 23 October 2007

Platelet-mediated thrombosis and drug-eluting stents

scientific article published on December 2011

Platelets as mediators of inflammation

scientific article published on February 2007

Platelets: developmental biology, physiology, and translatable platforms for preclinical investigation and drug development.

scientific article published on June 2008

Point-of-care determination of baseline platelet function as a predictor of clinical outcomes in patients who present to the emergency department with chest pain

scientific article

Prasugrel may be safe for further testing in people undergoing PCI. Commentary

scientific article published on 2 November 2005

Prescription Extraction from Clinical Notes: Towards Automating EMR Medication Reconciliation

scientific article published on 25 March 2015

Prevalence of heart failure signs and symptoms in a large primary care population identified through the use of text and data mining of the electronic health record

scientific article

Privacy and security in the era of digital health: what should translational researchers know and do about it?

scientific article

Prolonged dual antiplatelet therapy after percutaneous coronary intervention reduces ischemic events without affecting the need for repeat revascularization: insights from the CREDO trial

scientific article (publication date: July 2007)

Rationale and design of a home-based trial using wearable sensors to detect asymptomatic atrial fibrillation in a targeted population: The mHealth Screening To Prevent Strokes (mSToPS) trial

scientific article

Real world usage characteristics of a novel mobile health self-monitoring device: Results from the Scanadu Consumer Health Outcomes (SCOUT) Study

article

Relation of platelet inactivation with intravenous glycoprotein IIb/IIIa antagonists to major bleeding (from the GOLD study)

scientific article published on 01 June 2002

Relationship between activated clotting time and ischemic or hemorrhagic complications: analysis of 4 recent randomized clinical trials of percutaneous coronary intervention

scientific article (publication date: 24 August 2004)

Remote Sensing of Vital Signs: A Wearable, Wireless "Band-Aid" Sensor With Personalized Analytics for Improved Ebola Patient Care and Worker Safety

scientific article

Resistance to antiplatelet resistance is it justified?

scientific article (publication date: 7 June 2005)

Rethinking the medical record

scientific article published on 15 March 2018

Risk reduction with long-term clopidogrel following percutaneous coronary intervention

scientific article published in December 2004

Risk stratification for patients undergoing nonurgent percutaneous coronary intervention using N-terminal pro-B-type natriuretic peptide: a Clopidogrel for the Reduction of Events During Observation (CREDO) substudy

scientific article published in January 2007

Risk stratifying the acute coronary syndrome patient: a focus on treatable risk.

scientific article published on January 2007

Safety and efficacy of aspirin, clopidogrel, and warfarin after coronary stent placement in patients with an indication for anticoagulation

scientific article (publication date: March 2004)

Salivary biomarkers associated with myocardial necrosis: results from an alcohol septal ablation model

scientific article published on 28 September 2012

Self-Monitoring Utilization Patterns Among Individuals in an Incentivized Program for Healthy Behaviors.

scientific article

Smoking, clopidogrel, and mortality in patients with established cardiovascular disease

scientific article

The Healthy Pregnancy Research Program: Transforming Pregnancy Research Through a ResearchKit App

article published in 2018

The Healthy Pregnancy Research Program: transforming pregnancy research through a ResearchKit app

scientific article published on 05 September 2018

The Influence of Wireless Self-Monitoring Program on the Relationship Between Patient Activation and Health Behaviors, Medication Adherence, and Blood Pressure Levels in Hypertensive Patients: A Substudy of a Randomized Controlled Trial

scientific article published on 22 June 2016

The Ultegra rapid platelet-function assay: comparison to standard platelet function assays in patients undergoing percutaneous coronary intervention with abciximab therapy.

scientific article published in April 2002

The digital phenotype of vaccination

scientific article published in 2022

The digitised clinical trial

scientific article published on 9 November 2017

The efficacy and safety of short- and long-term dual antiplatelet therapy in patients with mild or moderate chronic kidney disease: results from the Clopidogrel for the Reduction of Events During Observation (CREDO) trial

scientific article published on 21 February 2008

The emerging field of mobile health

scientific article

The evolving algorithm concerning higher-risk PCI (TEACH-PCI). Introduction.

scientific article published in January 2007

The future of individualized health maintenance

scientific article published on 01 May 2019

The illusion of "optimal" platelet inhibition

scientific article published on 01 March 2012

The influence of body mass index on mortality and bleeding among patients with or at high-risk of atherothrombotic disease

scientific article published on 20 February 2009

The relative efficacy and safety of clopidogrel in women and men a sex-specific collaborative meta-analysis

scientific article

The role of the platelet in the pathogenesis of atherothrombosis

scientific article (publication date: 2005)

The use of anti-inflammatory analgesics in the patient with cardiovascular disease: what a pain

scientific article (publication date: 19 April 2005)

Ticagrelor: the first novel reversible P2Y(12) inhibitor

scientific article published on 27 December 2012

Time to coronary angiography and outcomes among patients with high-risk non ST-segment elevation acute coronary syndromes: results from the SYNERGY trial

scientific article published on 19 November 2007

Towards a smart medical home

scientific article published in January 2017

Transitioning patients from cangrelor to clopidogrel: pharmacodynamic evidence of a competitive effect

scientific article published on 13 July 2007

Usability of a Wrist-Worn Smartwatch in a Direct-to-Participant Randomized Pragmatic Clinical Trial

scientific article published on 01 September 2019

Usefulness of the response to sublingual nitroglycerin as a predictor of ischemic chest pain in the emergency department

scientific article published on 01 December 2002

Validation of a portable, deployable system for continuous vital sign monitoring using a multiparametric wearable sensor and personalised analytics in an Ebola treatment centre

scientific article published on April 2016

Validity of Using Inpatient and Outpatient Administrative Codes to Identify Acute Venous Thromboembolism: The CVRN VTE Study

scientific article

Variability in platelet responsiveness to clopidogrel among 544 individuals.

scientific article published on January 2005

Variable response to antiplatelet therapy: what does it mean to clinicians?

scientific article published on January 2007

Variation in the definitions of bleeding in clinical trials of patients with acute coronary syndromes and undergoing percutaneous coronary interventions and its impact on the apparent safety of antithrombotic drugs

scientific article published on July 2007

Virtual care for improved global health

scientific article

Vulnerable plaque intervention: State of the art.

scientific article published on February 2008

Wearable sensor data and self-reported symptoms for COVID-19 detection

scientific article published on 29 October 2020

Your digital nutritionist.

scientific article published in January 2019