List of works - Magalie Lecourtois

Argyrophilic grain disease: synergistic component of dementia?

scientific article

Both cytoplasmic and nuclear accumulations of the protein are neurotoxic in Drosophila models of TDP-43 proteinopathies.

scientific article published on 14 October 2010

Cytoskeleton proteins are modulators of mutant tau-induced neurodegeneration in Drosophila.

scientific article published on 19 February 2007

Detection of all adult Tau isoforms in a 3D culture model of iPSC-derived neurons

scientific article published on 23 August 2019

Drosophila models of human tauopathies indicate that Tau protein toxicity in vivo is mediated by soluble cytosolic phosphorylated forms of the protein.

scientific article published on 27 February 2010

Enhancing Mitofusin/Marf ameliorates neuromuscular dysfunction in Drosophila models of TDP-43 proteinopathies.

scientific article published on 27 February 2017

FTLD/ALS-linked TDP-43 mutations do not alter TDP-43's ability to self-regulate its expression in Drosophila

scientific article published on 17 May 2018

Filamin-A and Myosin VI colocalize with fibrillary Tau protein in Alzheimer's disease and FTDP-17 brains

scientific article published on 10 May 2010

Human lissencephaly with cerebellar hypoplasia due to mutations in TUBA1A: expansion of the foetal neuropathological phenotype

scientific article published on 8 April 2010

Identification of TCERG1 as a new genetic modulator of TDP-43 production in Drosophila

scientific article published on 12 December 2018

Impaired SorLA maturation and trafficking as a new mechanism for SORL1 missense variants in Alzheimer disease

scientific article published on 18 December 2021

Important neuronal toxicity of microtubule-bound Tau in vivo in Drosophila.

scientific article published on 24 June 2011

Inhibition of proteasome and Shaggy/Glycogen synthase kinase-3beta kinase prevents clearance of phosphorylated tau in Drosophila.

scientific article published in October 2006

Lack of miRNA Misregulation at Early Pathological Stages in Drosophila Neurodegenerative Disease Models.

scientific article

Molecular characterization of human stathmin expressed in Escherichia coli: site-directed mutagenesis of two phosphorylatable serines (Ser-25 and Ser-63)

scientific article

Neuron-to-Neuron Transfer of FUS in Drosophila Primary Neuronal Culture Is Enhanced by ALS-Associated Mutations.

scientific article published on 20 April 2017

Protein kinase CK-1 inhibitors as new potential drugs for amyotrophic lateral sclerosis

scientific article

Regulated endocytic routing modulates wingless signaling in Drosophila embryos.

scientific article published on June 2001

Splicing factors act as genetic modulators of TDP-43 production in a new autoregulatory TDP-43 Drosophila model

scientific article published on September 2017

The activity of Drosophila Hairless is required in pupae but not in embryos to inhibit Notch signal transduction.

scientific article

The neurogenic suppressor of hairless DNA-binding protein mediates the transcriptional activation of the enhancer of split complex genes triggered by Notch signaling.

scientific article published in November 1995

Transcriptional repression by suppressor of hairless involves the binding of a hairless-dCtBP complex in Drosophila.

scientific article published in May 2001

Trisomy for synaptojanin1 in Down syndrome is functionally linked to the enlargement of early endosomes

scientific journal article

Vascular endothelial growth factor and its high-affinity receptor (VEGFR-2) are highly expressed in the human forebrain and cerebellum during development.

scientific article published in February 2010

List of works by Magalie Lecourtois

Argyrophilic grain disease: synergistic component of dementia?

Both cytoplasmic and nuclear accumulations of the protein are neurotoxic in Drosophila models of TDP-43 proteinopathies.

Cytoskeleton proteins are modulators of mutant tau-induced neurodegeneration in Drosophila.

Detection of all adult Tau isoforms in a 3D culture model of iPSC-derived neurons

Drosophila models of human tauopathies indicate that Tau protein toxicity in vivo is mediated by soluble cytosolic phosphorylated forms of the protein.

Enhancing Mitofusin/Marf ameliorates neuromuscular dysfunction in Drosophila models of TDP-43 proteinopathies.

FTLD/ALS-linked TDP-43 mutations do not alter TDP-43's ability to self-regulate its expression in Drosophila

Filamin-A and Myosin VI colocalize with fibrillary Tau protein in Alzheimer's disease and FTDP-17 brains

Human lissencephaly with cerebellar hypoplasia due to mutations in TUBA1A: expansion of the foetal neuropathological phenotype

Identification of TCERG1 as a new genetic modulator of TDP-43 production in Drosophila

Impaired SorLA maturation and trafficking as a new mechanism for SORL1 missense variants in Alzheimer disease

Important neuronal toxicity of microtubule-bound Tau in vivo in Drosophila.

Inhibition of proteasome and Shaggy/Glycogen synthase kinase-3beta kinase prevents clearance of phosphorylated tau in Drosophila.

Lack of miRNA Misregulation at Early Pathological Stages in Drosophila Neurodegenerative Disease Models.

Molecular characterization of human stathmin expressed in Escherichia coli: site-directed mutagenesis of two phosphorylatable serines (Ser-25 and Ser-63)

Neuron-to-Neuron Transfer of FUS in Drosophila Primary Neuronal Culture Is Enhanced by ALS-Associated Mutations.

Protein kinase CK-1 inhibitors as new potential drugs for amyotrophic lateral sclerosis

Regulated endocytic routing modulates wingless signaling in Drosophila embryos.

Splicing factors act as genetic modulators of TDP-43 production in a new autoregulatory TDP-43 Drosophila model

The activity of Drosophila Hairless is required in pupae but not in embryos to inhibit Notch signal transduction.

The neurogenic suppressor of hairless DNA-binding protein mediates the transcriptional activation of the enhancer of split complex genes triggered by Notch signaling.

Transcriptional repression by suppressor of hairless involves the binding of a hairless-dCtBP complex in Drosophila.

Trisomy for synaptojanin1 in Down syndrome is functionally linked to the enlargement of early endosomes

Vascular endothelial growth factor and its high-affinity receptor (VEGFR-2) are highly expressed in the human forebrain and cerebellum during development.