List of works - Catherine H Regnier

2-Amino-aryl-7-aryl-benzoxazoles as potent, selective and orally available JAK2 inhibitors.

scientific article published on 21 January 2010

Characterization of immune functions in TRAF4-deficient mice

scientific article published on 18 February 2008

Deficiency of MALT1 paracaspase activity results in unbalanced regulatory and effector T and B cell responses leading to multiorgan inflammation

scientific article

Discovery and SAR of potent, orally available 2,8-diaryl-quinoxalines as a new class of JAK2 inhibitors

scientific article

Expression of a truncated form of hHb1 hair keratin in human breast carcinomas.

scientific article

Expression of human hair keratin basic 1 in pilomatrixoma. A study of 128 cases

scientific article published on 01 April 1999

Expression pattern of human hair keratin basic 1 (hHbl) in hair follicle and pilomatricoma ⬇️

scientific article published on April 1, 1997

Genetic resistance to JAK2 enzymatic inhibitors is overcome by HSP90 inhibition ⬇️

scientific article published on January 23, 2012

Hereditary complement C7 deficiency in nine families: Subtotal C7 deficiency revisited

scientific article published on 01 May 2007

Hyperfunctional C3 convertase leads to complement deposition on endothelial cells and contributes to atypical hemolytic uremic syndrome

scientific article

Identification and characterization of an IkappaB kinase

scientific article (publication date: 25 July 1997)

Identification of four novel human genes amplified and overexpressed in breast carcinoma and localized to the q11-q21.3 region of chromosome 17

scientific article

Impaired neural tube closure, axial skeleton malformations, and tracheal ring disruption in TRAF4-deficient mice.

scientific article

Improved cancer immunotherapy by a CD25-mimobody conferring selectivity to human interleukin-2.

scientific article published on November 2016

Lasp-1 (MLN 50) defines a new LIM protein subfamily characterized by the association of LIM and SH3 domains

scientific article

Lasp-1, a novel type of actin-binding protein accumulating in cell membrane extensions

scientific article

Mutations in components of complement influence the outcome of Factor I-associated atypical hemolytic uremic syndrome

scientific article

Presence of a new conserved domain in CART1, a novel member of the tumor necrosis factor receptor-associated protein family, which is expressed in breast carcinoma

scientific article

Stromelysin-3 in the biology of the normal and neoplastic mammary gland.

scientific article published in April 1996

TRAF4 overexpression is a common characteristic of human carcinomas

scientific article published on 26 June 2006

The T-cell fingerprint of MALT1 paracaspase revealed by selective inhibition.

scientific article published on 21 December 2017

The identification and characterization of a STAT5 gene signature in hematologic malignancies.

scientific article published on January 2015

The paracaspase MALT1 cleaves HOIL1 reducing linear ubiquitination by LUBAC to dampen lymphocyte NF-κB signalling

scientific article

Transgenes encoding mutant simian virus 40 large T antigens unmask phenotypic and functional constraints in thymic epithelial cells.

scientific article

Tumor necrosis factor (TNF)-mediated kinase cascades: bifurcation of nuclear factor-kappaB and c-jun N-terminal kinase (JNK/SAPK) pathways at TNF receptor-associated factor 2

scientific article

Two Antagonistic MALT1 Auto-Cleavage Mechanisms Reveal a Role for TRAF6 to Unleash MALT1 Activation

scientific article

Two distinct amplified regions at 17q11-q21 involved in human primary breast cancer

scientific article published on 01 September 1996

List of works by Catherine H Regnier

2-Amino-aryl-7-aryl-benzoxazoles as potent, selective and orally available JAK2 inhibitors.

Characterization of immune functions in TRAF4-deficient mice

Deficiency of MALT1 paracaspase activity results in unbalanced regulatory and effector T and B cell responses leading to multiorgan inflammation

Discovery and SAR of potent, orally available 2,8-diaryl-quinoxalines as a new class of JAK2 inhibitors

Expression of a truncated form of hHb1 hair keratin in human breast carcinomas.

Expression of human hair keratin basic 1 in pilomatrixoma. A study of 128 cases

Expression pattern of human hair keratin basic 1 (hHbl) in hair follicle and pilomatricoma ⬇️

Genetic resistance to JAK2 enzymatic inhibitors is overcome by HSP90 inhibition ⬇️

Hereditary complement C7 deficiency in nine families: Subtotal C7 deficiency revisited

Hyperfunctional C3 convertase leads to complement deposition on endothelial cells and contributes to atypical hemolytic uremic syndrome

Identification and characterization of an IkappaB kinase

Identification of four novel human genes amplified and overexpressed in breast carcinoma and localized to the q11-q21.3 region of chromosome 17

Impaired neural tube closure, axial skeleton malformations, and tracheal ring disruption in TRAF4-deficient mice.

Improved cancer immunotherapy by a CD25-mimobody conferring selectivity to human interleukin-2.

Lasp-1 (MLN 50) defines a new LIM protein subfamily characterized by the association of LIM and SH3 domains

Lasp-1, a novel type of actin-binding protein accumulating in cell membrane extensions

Mutations in components of complement influence the outcome of Factor I-associated atypical hemolytic uremic syndrome

Presence of a new conserved domain in CART1, a novel member of the tumor necrosis factor receptor-associated protein family, which is expressed in breast carcinoma

Stromelysin-3 in the biology of the normal and neoplastic mammary gland.

TRAF4 overexpression is a common characteristic of human carcinomas

The T-cell fingerprint of MALT1 paracaspase revealed by selective inhibition.

The identification and characterization of a STAT5 gene signature in hematologic malignancies.

The paracaspase MALT1 cleaves HOIL1 reducing linear ubiquitination by LUBAC to dampen lymphocyte NF-κB signalling

Transgenes encoding mutant simian virus 40 large T antigens unmask phenotypic and functional constraints in thymic epithelial cells.

Tumor necrosis factor (TNF)-mediated kinase cascades: bifurcation of nuclear factor-kappaB and c-jun N-terminal kinase (JNK/SAPK) pathways at TNF receptor-associated factor 2

Two Antagonistic MALT1 Auto-Cleavage Mechanisms Reveal a Role for TRAF6 to Unleash MALT1 Activation

Two distinct amplified regions at 17q11-q21 involved in human primary breast cancer