List of works - Apolinar Maya-Mendoza

A global but stable change in HeLa cell morphology induces reorganization of DNA structural loop domains within the cell nucleus.

scientific article published on September 2005

AMBRA1 regulates cyclin D to guard S-phase entry and genomic integrity

scientific article published on 14 April 2021

Autophagy role(s) in response to oncogenes and DNA replication stress

scientific article published on 14 August 2019

B-Myb is critical for proper DNA duplication during an unperturbed S phase in mouse embryonic stem cells

scientific article

BRCA1-regulated RRM2 expression protects glioblastoma cells from endogenous replication stress and promotes tumorigenicity

scientific article

Chk1 regulates the density of active replication origins during the vertebrate S phase.

scientific article published on 10 May 2007

Chronic p53-independent p21 expression causes genomic instability by deregulating replication licensing

scientific article published on 20 June 2016

Continued stabilization of the nuclear higher-order structure of post-mitotic neurons in vivo

scientific article (publication date: 2011)

Cytoskeletal protein filamin A is a nucleolar protein that suppresses ribosomal RNA gene transcription

scientific article

Differential Activity of ATR and WEE1 Inhibitors in a Highly Sensitive Subpopulation of DLBCL Linked to Replication Stress

scientific article published on 23 May 2019

EdU induces DNA damage response and cell death in mESC in culture.

scientific article published on 6 March 2013

Gene positional changes relative to the nuclear substructure correlate with the proliferating status of hepatocytes during liver regeneration

scientific article (publication date: November 2003)

Gene positional changes relative to the nuclear substructure during carbon tetrachloride-induced hepatic fibrosis in rats.

scientific article published in December 2004

High speed of fork progression induces DNA replication stress and genomic instability

scientific article published in Nature

Immortalised breast epithelia survive prolonged DNA replication stress and return to cycle from a senescent-like state.

scientific article

Innate structure of DNA foci restricts the mixing of DNA from different chromosome territories

scientific article (publication date: 2011)

Interaction with checkpoint kinase 1 modulates the recruitment of nucleophosmin to chromatin.

scientific article

Labeling DNA Replication Foci to Visualize Chromosome Territories In Vivo

scientific article published on 19 June 2017

Mechanisms regulating S phase progression in mammalian cells

scientific article published on January 2009

Myc and Ras oncogenes engage different energy metabolism programs and evoke distinct patterns of oxidative and DNA replication stress

scientific article

Natural ageing in the rat liver correlates with progressive stabilisation of DNA-nuclear matrix interactions and withdrawal of genes from the nuclear substructure

scientific article published on 12 April 2005

Pharmacological activation of a novel p53-dependent S-phase checkpoint involving CHK-1

scientific article

Positional mapping of specific DNA sequences relative to the nuclear substructure by direct polymerase chain reaction on nuclear matrix-bound templates

scientific article published on 01 February 2003

Reduced expression of lamin A/C results in modified cell signaling and metabolism coupled with changes in expression of structural proteins

scientific article published on 01 November 2009

Regulation of replication fork speed: Mechanisms and impact on genomic stability

scientific article published on 08 July 2019

Replication timing: findings from fibers.

scientific article

S phase progression in human cells is dictated by the genetic continuity of DNA foci

scientific article (publication date: April 2010)

S-phase progression in mammalian cells: modelling the influence of nuclear organization.

scientific article published on January 2010

SETD2 loss-of-function promotes renal cancer branched evolution through replication stress and impaired DNA repair

scientific article

SPOP promotes transcriptional expression of DNA repair and replication factors to prevent replication stress and genomic instability

Signal transduction controls heterogeneous NF-κB dynamics and target gene expression through cytokine-specific refractory states

scientific article

TOPBP1 regulates RAD51 phosphorylation and chromatin loading and determines PARP inhibitor sensitivity

scientific article published on 25 January 2016

The integrity of a lamin-B1-dependent nucleoskeleton is a fundamental determinant of RNA synthesis in human cells

scientific article published on 11 March 2008

Visualising chromosomal replication sites and replicons in mammalian cells.

scientific article published on 6 June 2012

p53 at the crossroad of DNA replication and ribosome biogenesis stress pathways

scientific article published in 2022

List of works by Apolinar Maya-Mendoza

A global but stable change in HeLa cell morphology induces reorganization of DNA structural loop domains within the cell nucleus.

AMBRA1 regulates cyclin D to guard S-phase entry and genomic integrity

Autophagy role(s) in response to oncogenes and DNA replication stress

B-Myb is critical for proper DNA duplication during an unperturbed S phase in mouse embryonic stem cells

BRCA1-regulated RRM2 expression protects glioblastoma cells from endogenous replication stress and promotes tumorigenicity

Chk1 regulates the density of active replication origins during the vertebrate S phase.

Chronic p53-independent p21 expression causes genomic instability by deregulating replication licensing

Continued stabilization of the nuclear higher-order structure of post-mitotic neurons in vivo

Cytoskeletal protein filamin A is a nucleolar protein that suppresses ribosomal RNA gene transcription

Differential Activity of ATR and WEE1 Inhibitors in a Highly Sensitive Subpopulation of DLBCL Linked to Replication Stress

EdU induces DNA damage response and cell death in mESC in culture.

Gene positional changes relative to the nuclear substructure correlate with the proliferating status of hepatocytes during liver regeneration

Gene positional changes relative to the nuclear substructure during carbon tetrachloride-induced hepatic fibrosis in rats.

High speed of fork progression induces DNA replication stress and genomic instability

Immortalised breast epithelia survive prolonged DNA replication stress and return to cycle from a senescent-like state.

Innate structure of DNA foci restricts the mixing of DNA from different chromosome territories

Interaction with checkpoint kinase 1 modulates the recruitment of nucleophosmin to chromatin.

Labeling DNA Replication Foci to Visualize Chromosome Territories In Vivo

Mechanisms regulating S phase progression in mammalian cells

Myc and Ras oncogenes engage different energy metabolism programs and evoke distinct patterns of oxidative and DNA replication stress

Natural ageing in the rat liver correlates with progressive stabilisation of DNA-nuclear matrix interactions and withdrawal of genes from the nuclear substructure

Pharmacological activation of a novel p53-dependent S-phase checkpoint involving CHK-1

Positional mapping of specific DNA sequences relative to the nuclear substructure by direct polymerase chain reaction on nuclear matrix-bound templates

Reduced expression of lamin A/C results in modified cell signaling and metabolism coupled with changes in expression of structural proteins

Regulation of replication fork speed: Mechanisms and impact on genomic stability

Replication timing: findings from fibers.

S phase progression in human cells is dictated by the genetic continuity of DNA foci

S-phase progression in mammalian cells: modelling the influence of nuclear organization.

SETD2 loss-of-function promotes renal cancer branched evolution through replication stress and impaired DNA repair

SPOP promotes transcriptional expression of DNA repair and replication factors to prevent replication stress and genomic instability

Signal transduction controls heterogeneous NF-κB dynamics and target gene expression through cytokine-specific refractory states

TOPBP1 regulates RAD51 phosphorylation and chromatin loading and determines PARP inhibitor sensitivity

The integrity of a lamin-B1-dependent nucleoskeleton is a fundamental determinant of RNA synthesis in human cells

Visualising chromosomal replication sites and replicons in mammalian cells.

p53 at the crossroad of DNA replication and ribosome biogenesis stress pathways